keyword
https://read.qxmd.com/read/38704280/painful-raynaud-s-mimics
#1
REVIEW
Carleigh Zahn, Cindy Puga, Aroosa Malik, Dinesh Khanna
Raynaud's syndrome is a common finding in many autoimmune conditions. Accurately diagnosing Raynaud's, and differentiating it from mimicking conditions, is imperative in rheumatologic diseases. Raynaud's syndrome and Raynaud's mimickers, especially painful Raynaud's mimickers, can prove a diagnostic challenge for the practicing rheumatologist. Painful Raynaud's mimickers can lead to increased patient stress and unnecessary medical work up; Healthcare providers need to be aware of Raynaud's mimickers when evaluating patient concerns of skin color changes and pain...
May 3, 2024: Best Practice & Research. Clinical Rheumatology
https://read.qxmd.com/read/38703970/the-cardiovascular-pathologist-in-the-aortic-team
#2
REVIEW
Angela Pucci, Martina Rossetti, Chiara Lenzi, L Maximilian Buja
Aortic diseases require a multidisciplinary management for diagnosis, treatment and follow-up with better outcomes in referral centers using a team-based approach. The setting up of a multi-disciplinary aortic team for the discussion of complex cases has been already proposed; it is also supported by the ACC/AHA. Surgeons and radiologists, more or less other physicians such as cardiologists, geneticists, rheumatologists/internal medicine specialists and pathologists are involved into such a team. The role of the cardiovascular pathologist is to examine the aortic specimens, to diagnose and classify the aortic lesions...
May 2, 2024: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://read.qxmd.com/read/38698101/guidelines-for-fracture-risk-assessment-and-management-of-osteoporosis-in-postmenopausal-women-and-men-above-the-age-of-50-in-qatar
#3
JOURNAL ARTICLE
Fiaz Alam, Omar Alsaed, Nabeel Abdulla, Ibrahim Abdulmomen, Abdo Lutf, Samar Al Emadi
UNLABELLED: We present comprehensive guidelines for osteoporosis management in Qatar. Formulated by the Qatar Osteoporosis Association, the guidelines recommend the age-dependent Qatar fracture risk assessment tool for screening, emphasizing risk-based treatment strategies and discouraging routine dual-energy X-ray scans. They offer a vital resource for physicians managing osteoporosis and fragility fractures nationwide. PURPOSE: Osteoporosis and related fragility fractures are a growing public health issue with an impact on individuals and the healthcare system...
May 2, 2024: Archives of Osteoporosis
https://read.qxmd.com/read/38693734/saudi-national-clinical-practice-guidelines-for-management-of-adult-systemic-lupus-erythematosus
#4
JOURNAL ARTICLE
Ahmed H Al-Jedai, Hajer Y Almudaiheem, Ibrahim A Al-Homood, Ibrahim Almaghlouth, Sami M Bahlas, Abdulaziz Mohammed Alolaiw, Mohammad Fatani, Maysa Tariq Eshmawi, Bedor A AlOmari, Khalidah Ahmed Alenzi, Rayan G Albarakat, Nayef Al Ghanim
OBJECTIVE: To provide evidence-based clinical practice recommendations for managing Systemic Lupus Erythematosus (SLE) in Saudi Arabia. METHODS: This EULAR-adapted national guideline in which a multidisciplinary task force utilized the modified Delphi method to develop 31 clinical key questions. A systematic literature review was conducted to update the evidence since the EULAR publication. After reaching a consensus agreement, two rounds of voting and group discussion were conducted to generate consolidated recommendations/statements...
April 30, 2024: Current Rheumatology Reviews
https://read.qxmd.com/read/38693680/patients-and-rheumatologists-perceptions-on-dose-reduction-of-rituximab-in-rheumatoid-arthritis
#5
JOURNAL ARTICLE
Delphine Bertrand, Anke Deprez, Michaël Doumen, Diederik De Cock, Sofia Pazmino, Anja Marchal, Marc Thelissen, Johan Joly, Elias De Meyst, Barbara Neerinckx, René Westhovens, Patrick Verschueren
OBJECTIVE: The recommended dose of a rituximab course for the treatment of Rheumatoid Arthritis (RA) consists of two infusions of 1000 mg with a 2-week interval. Evidence is growing that a lower dose could be as effective. We aimed to investigate patients' and rheumatologists' perceptions on dose reduction of rituximab. METHODS: Patients with RA treated with rituximab, and rheumatologists were invited for a qualitative study via individual semi-structured interviews...
June 2024: Musculoskeletal Care
https://read.qxmd.com/read/38693507/correlation-between-benign-joint-hypermobility-syndrome-and-headache-in-children-and-adolescents
#6
JOURNAL ARTICLE
Mohsen Jari, Sogol Alesaeidi
BACKGROUND: Benign Joint Hypermobility Syndrome (BJHS) is a most common hereditary connective tissue disorders in children and adolescents. This study aimed to investigate the prevalence and subtypes of headache in children with BJHS. METHODS: This observational-analytical study was conducted in a case-control setting on school children aged 7 to 16 years in 2021-2023 in Isfahan, Iran. Students were examined for BJHS using Beighton criteria by a pediatric rheumatologist...
May 2, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38692915/a-preliminary-survey-of-rheumatologists-on-the-management-of-late-onset-rheumatoid-arthritis-in-japan
#7
JOURNAL ARTICLE
Satoshi Takanashi, Yuko Kaneko, Yutaka Kawahito, Takashi Kida, Takahiko Sugihara, Toshihisa Kojima, Ryozo Harada, Michinori Ishitoku, Shintaro Hirata, Motomu Hashimoto, Toshihiko Hidaka, Asami Abe, Hajime Ishikawa, Hiromu Ito, Mitsumasa Kishimoto, Kazuo Matsui, Toshihiro Matsui, Isao Matsushita, Akira Onishi, Akio Morinobu, Keiichiro Nishida, Shuji Asai, Eiichi Tanaka, Masayoshi Harigai, Masayo Kojima
Objectives We investigated the current perspectives regarding the management of late-onset rheumatoid arthritis (LORA) among rheumatologists in clinical practice. Methods This study was performed in October 2021, and included 65 rheumatologists certified by the Japan College of Rheumatology, who were administered questionnaires (including multiple choice and descriptive formulae) regarding the management of LORA. We aggregated and analyzed the responses. Results All 65 rheumatologists responded to the survey; 47 (72%) answered that >50% of newly diagnosed patients were aged ≥65 years, 42 (65%) answered that achievement of remission or low disease activity was the treatment goal, and 40 (62%) considered patient safety to be the highest priority...
May 2, 2024: Internal Medicine
https://read.qxmd.com/read/38691248/rheumatoid-arthritis-associated-complications-during-pregnancy-and-its-effect-on-offspring-comprehensive-review
#8
REVIEW
S Rohini, Uday Raj Sharma, M Vinutha, D Shreelaxmi, Surendra Vada, Suresh Janandri, T Haribabu, Nageena Taj, S V Gayathri, Abhishek Ghara, Manjunatha P Mudagal
This study comprehensively explores the complexities of rheumatoid arthritis during pregnancy and its impact on offspring. Through an extensive review of existing literature, we investigate maternal and fetal risks, including adverse pregnancy outcomes and developmental issues in offspring. Utilizing reputable databases such as PubMed, Google Scholar, and Science Direct, we meticulously examined studies exploring the connection between rheumatoid arthritis and pregnancy complications, with a focus on outcomes for offspring...
April 30, 2024: Inflammopharmacology
https://read.qxmd.com/read/38690543/development-of-a-shape-based-algorithm-for-identification-of-asymptomatic-vertebral-compression-fractures-a-proof-of-principle-study
#9
JOURNAL ARTICLE
Huy G Nguyen, Hoa T Nguyen, Linh T T Nguyen, Thach S Tran, Lan T Ho-Pham, Sai H Ling, Tuan V Nguyen
OBJECTIVES: Vertebral fracture is both common and serious among adults, yet it often goes undiagnosed. This study aimed to develop a shape-based algorithm (SBA) for the automatic identification of vertebral fractures. METHODS: The study included 144 participants (50 individuals with a fracture and 94 without a fracture) whose plain thoracolumbar spine X-rays were taken. Clinical diagnosis of vertebral fracture (grade 0 to 3) was made by rheumatologists using Genant's semiquantitative method...
March 2024: Osteoporosis and Sarcopenia
https://read.qxmd.com/read/38687285/sacroiliitis-in-inflammatory-bowel-disease
#10
JOURNAL ARTICLE
Fardina Malik, Michael H Weisman
PURPOSE OF REVIEW: This review summarizes the recent evidence regarding the epidemiology of inflammatory bowel disease (IBD) associated sacroiliitis, including the prevalence, pathogenesis, role of imaging, and therapeutic challenges. RECENT FINDINGS: Sacroiliitis is an underappreciated musculoskeletal manifestation of IBD, a chronic inflammatory condition of the gut affecting the younger population. Untreated sacroiliitis can lead to joint destruction and chronic pain, further adding to morbidity in IBD patients...
May 1, 2024: Current Opinion in Rheumatology
https://read.qxmd.com/read/38687221/case-328
#11
JOURNAL ARTICLE
Cristina Agostinis, Elide Lupi
A 45-year-old female patient with diffuse osteoarticular pain, particularly low back pain, was referred by a rheumatologist for an updated radiologic evaluation. The patient had experienced these symptoms for many years and was diagnosed with human leukocyte antigen B27-negative spondyloarthritis approximately 11 years prior, based on findings of bilateral erosive sacroiliitis at pelvic radiography (Fig 1A) and bone scintigraphy with technetium 99m methylene diphosphonate (Fig 1B). After 3 years of treatment with a tumor necrosis factor-α inhibitor (adalimumab), which was effective for pain, the patient was lost to follow-up...
April 2024: Radiology
https://read.qxmd.com/read/38682570/defining-criteria-for-disease-activity-states-in-systemic-juvenile-idiopathic-arthritis-based-on-the-systemic-juvenile-arthritis-disease-activity-score
#12
JOURNAL ARTICLE
Silvia Rosina, Ana I Rebollo-Gimenez, Letizia Tarantola, Angela Pistorio, Yulia Vyzhga, Yasser El Miedany, Hala M Lotfy, Hend Abu-Shady, Mervat Eissa, Naglaa S Osman, Waleed Hassan, Marwa Y Mahgoub, Nermeen A Fouad, Doaa M Mosa, Yasmin Adel, Sheren E M Mohamed, Ahmed R Radwan, Mohamed H Abu-Zaid, Samar A A Tabra, Radwa H Shalaby, Samah I Nasef, Raju Khubchandani, Archana Khan, Naziya P Maldar, Seza Ozen, Yagmur Bayindir, Motasem Alsuweiti, Raed Alzyoud, Hiba Almaaitah, Soamarat Vilaiyuk, Butsabong Lerkvaleekul, Ekaterina Alexeeva, Tatyana Dvoryakovskaya, Ivan Kriulin, Claudia Bracaglia, Manuela Pardeo, Fabrizio De Benedetti, Francesco Licciardi, Davide Montin, Francesca Robasto, Francesca Minoia, Giovanni Filocamo, Martina Rossano, Gabriele Simonini, Edoardo Marrani, Sarah Abu-Rumeleih, Mikhail M Kostik, Konstantin E Belozerov, Priyankar Pal, Jigna N Bathia, María M Katsicas, Giselle Villarreal, Achille Marino, Stefania Costi, Flavio Sztajnbok, Rodrigo M Silva, Maria C Maggio, Dalia H El-Ghoneimy, Rasha El Owaidy, Adele Civino, Federico Diomeda, Sulaiman M Al-Mayouf, Fuad Al-Sofyani, Zane Dāvidsone, Elisa Patrone, Claudia Saad-Magalhães, Alessandro Consolaro, Angelo Ravelli
OBJECTIVE: To develop and validate cutoff values in the systemic Juvenile Arthritis Disease Activity Score 10 (sJADAS10) that distinguish the states of inactive disease (ID), minimal disease activity (MiDA), moderate disease activity (MoDA), and high disease activity (HDA) in children with systemic juvenile idiopathic arthritis (sJIA), based on subjective disease state assessment by the treating pediatric rheumatologist. METHODS: The cutoffs definition cohort was composed of 400 patients enrolled at 30 pediatric rheumatology centers in 11 countries...
April 29, 2024: Arthritis & Rheumatology
https://read.qxmd.com/read/38676142/design-of-a-self-measuring-device-based-on-bioelectrical-impedance-analysis-for-regular-monitoring-of-rheumatoid-arthritis
#13
JOURNAL ARTICLE
JuYoung Jeong, Yun Soo Park, Eunchae Lee, SeoYoun Choi, Dokshin Lim, Jiho Kim
Rheumatoid arthritis (RA) is a chronic disease, in which permanent joint deformation is largely preventable with the timely introduction of appropriate treatment strategies. However, there is no consensus for patients with RA to monitor their progress and communicate it to the rheumatologist till the condition progresses to remission. In response to this unmet need, we proposed the design of a self-measuring device based on bioelectrical impedance analysis (BIA) for regular monitoring of inflammation levels...
April 15, 2024: Sensors
https://read.qxmd.com/read/38674242/influence-of-the-covid-19-pandemic-on-medical-management-and-on-healthcare-delivery-of-immune-mediated-rheumatic-and-musculoskeletal-diseases-during-the-first-pandemic-period-february-to-july-2020-a-systematic-review
#14
REVIEW
Marco Schlegel, Stefan Bachmann
(1) Background and Objectives : The COVID-19 pandemic influenced the management of patients with immune-mediated rheumatic and musculoskeletal diseases (imRMDs) in various ways. The goal of our systematic review was to determine the influence of the first period of the COVID-19 pandemic (February 2020 to July 2020) on the management of imRMDs regarding the availability of drugs, adherence to therapy and therapy changes and on healthcare delivery. (2) Materials and Methods : We conducted a systematic literature search of PubMed, Cochrane and Embase databases (carried out 20-26 October 2021), including studies with adult patients, on the influence of the COVID-19 pandemic on the management of imRMDs...
April 4, 2024: Medicina
https://read.qxmd.com/read/38671475/to-be-or-not-to-b27-positive-implications-for-the-phenotypes-of-axial-spondyloarthritis-outcomes-data-from-a-large-multiracial-cohort-from-the-brazilian-registry-of-spondyloarthritis
#15
MULTICENTER STUDY
Gustavo Gomes Resende, Carla Goncalves Schahin Saad, Claudia Diniz Lopes Marques, Sandra Lúcia Euzébio Ribeiro, Maria Bernadete Renoldi de Oliveira Gavi, Michel Alexandre Yazbek, Adriana de Oliveira Marinho, Rita de Cássia Menin, Manuella Lima Gomes Ochtrop, Andressa Miozzo Soares, Nara Gualberto Cavalcanti, Jamille Nascimento Carneiro, Glaucio Ricardo Werner de Castro, José Mauro Carneiro Fernandes, Elziane da Cruz Ribeiro E Souza, Corina Quental de Menezes Alvarenga, Rejane Maria Rodrigues de Abreu Vieira, Natalia Pereira Machado, Antônio Carlos Ximenes, Morgana Ohira Gazzeta, Cleandro Pires de Albuquerque, Thelma Larocca Skare, Mauro Waldemar Keiserman, Charles Lubianca Kohem, Gabriel Sarkis Benacon, Vítor Florêncio Santos Rocha, Ricardo da Cruz Lage, Olivio Brito Malheiro, Rywka Tenenbaum Medeiros Golebiovski, Thauana Luiza Oliveira, Ruben Horst Duque, Ana Carolina Londe, Marcelo de Medeiros Pinheiro, Percival Degrava Sampaio-Barros
BACKGROUND: There is a remarkable variability in the frequency of HLA-B27 positivity in patients with spondyloarthritis (SpA), which may be associated with different clinical presentations worldwide. However, there is a lack of data considering ethnicity and sex on the evaluation of the main clinical and prognostic outcomes in mixed-race populations. The aim of this study was to evaluate the frequency of HLA-B27 and its correlation with disease parameters in a large population of patients from the Brazilian Registry of Spondyloarthritis (RBE)...
April 26, 2024: Advances in Rheumatology
https://read.qxmd.com/read/38668398/the-value-of-ultrasound-for-detecting-and-following-subclinical-interstitial-lung-disease-in-systemic-sclerosis
#16
JOURNAL ARTICLE
Marwin Gutierrez, Chiara Bertolazzi, Edgar Zozoaga-Velazquez, Denise Clavijo-Cornejo
BACKGROUND: Interstitial lung disease (ILD) is a complication in patients with systemic sclerosis (SSc). Accurate strategies to identify its presence in early phases are essential. We conducted the study aiming to determine the validity of ultrasound (US) in detecting subclinical ILD in SSc, and to ascertain its potential in determining the disease progression. METHODS: 133 patients without respiratory symptoms and 133 healthy controls were included. Borg scale, Rodnan skin score (RSS), auscultation, chest radiographs, and respiratory function tests (RFT) were performed...
April 3, 2024: Tomography: a Journal for Imaging Research
https://read.qxmd.com/read/38664779/unraveling-the-genetic-collagen-connection-clinical-and-therapeutic-insights-on-genetic-connective-tissue-disorders
#17
REVIEW
Nilton Salles Rosa Neto, Ivânio Alves Pereira, Flávio Roberto Sztajnbok, Valderílio Feijó Azevedo
Hereditary connective tissue disorders include more than 200 conditions affecting different organs and tissues, compromising the biological role of the extracellular matrix through interference in the synthesis, development, or secretion of collagen and/or its associated proteins. The clinical phenotype includes multiple signs and symptoms, usually nonspecific but of interest to rheumatologists because of musculoskeletal involvement. The patient´s journey to diagnosis is long, and physicians should include these disorders in their differential diagnoses of diseases with systemic involvement...
April 25, 2024: Advances in Rheumatology
https://read.qxmd.com/read/38663881/optimising-gout-treatment-insights-from-a-nurse-led-cohort-study
#18
JOURNAL ARTICLE
Claus Rasmussen, Jesper Walther Larsen, Heidi Mächler Christensen, Monica Bak Larsen, Anna Marie Thomsen, Tinna Leishmann, Jette Kragh, Gunnar Lauge Nielsen
OBJECTIVES: Currently, gout management, particularly urate-lowering therapy (ULT), is often suboptimal. Nurses successfully manage various diseases including gout. As gout prevalence is rising, and rheumatologists and general practitioners face shortages, a new approach is imperative. This real-life prospective cohort study evaluated the effectiveness of nurse-led care employing a treat-to-target strategy for gout management over a 2-year period. METHODS: All consecutively confirmed gout patients were included...
April 24, 2024: RMD Open
https://read.qxmd.com/read/38653847/the-power-of-us-breaking-barriers-and-bridging-the-gap-of-ultrasound-in-rheumatology-to-empower-a-new-generation
#19
JOURNAL ARTICLE
Mario R Garcia-Pompermayer, Sarah G Ayton, Juan Molina-Collada, Giorgio Tamborrini, María Eugenia Díaz Sanchez, Karina Silva Luna, Mario Alberto Garza Elizondo
OBJECTIVE: This study assesses musculoskeletal ultrasound (MSUS) knowledge, attitudes, and practices among young rheumatologists in Mexico, aiming to identify barriers and facilitators to its clinical use. METHODS: An online survey distributed to a network of young rheumatologists captured demographics, institutional, and personal MSUS information. Multivariable analysis identified factors associated with positive MSUS attitudes. RESULTS: Ninety-six rheumatologists (39...
April 23, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38652403/antiphospholipid-patients-admitted-in-the-intensive-care-unit-what-must-the-rheumatologist-know
#20
REVIEW
Quentin Moyon, Alexis Mathian, Matthias Papo, Alain Combes, Zahir Amoura, Marc Pineton de Chambrun
PURPOSE OF THE REVIEW: Antiphospholipid syndrome (APS) is a rare systemic autoimmune disorder that can escalate into a 'thrombotic storm' called the catastrophic antiphospholipid syndrome (CAPS), frequently requiring ICU admission for multiple organ failure. This review aims to offer insight and recent evidence on critically-ill APS patients. RECENT FINDINGS: The CAPS classification criteria define this condition as the involvement of at least three organs/systems/tissues within less than a week, caused by small vessel thrombosis, in patients with elevated antiphospholipid antibodies levels...
April 23, 2024: Current Rheumatology Reports
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