Elisa Gouvea Gutman, Andreza Lemos Salvio, Renan Amphilophio Fernandes, Larissa Araujo Duarte, Jessica Vasques Raposo-Vedovi, Helena França Alcaraz, Milene Ataíde Teixeira, Giselle Fazzioni Passos, Karoline Queiroz Muniz de Medeiros, Mariana Beiral Hammerle, Karina Lebeis Pires, Claudia Cristina Ferreira Vasconcelos, Luciane Almeida Amado Leon, Cláudia Pinto Figueiredo, Soniza Vieira Alves-Leon
It is well known the potential of severe acute respiratory coronavirus type 2 (SARS-CoV-2) infection to induce post-acute sequelae, a condition called Long COVID. This syndrome includes several symptoms, but the central nervous system (CNS) main one is neurocognitive dysfunction. Recently it has been demonstrated the relevance of plasma levels of neurofilament light chain (pNfL), as a biomarker of early involvement of the CNS in COVID-19. The aim of this study was to investigate the relationship between pNfL in patients with post-acute neurocognitive symptoms and the potential of NfL as a prognostic biomarker in these cases...
April 27, 2024: Molecular Psychiatry