keyword
https://read.qxmd.com/read/38637129/participant-recruitment-and-attrition-in-surgical-randomised-trials-with-placebo-controls-versus-non-operative-controls-a-meta-epidemiological-study-and-meta-analysis
#41
JOURNAL ARTICLE
Pragadesh Natarajan, Spiro Menounos, Laura Harris, Masiath Monuja, Alexandra Gorelik, Teemu Karjalainen, Rachelle Buchbinder, Ian A Harris, Justine M Naylor, Sam Adie
OBJECTIVE: To compare differences in recruitment and attrition between placebo control randomised trials of surgery, and trials of the same surgical interventions and conditions that used non-operative (non-placebo) controls. DESIGN: Meta-epidemiological study. DATA SOURCES: Randomised controlled trials were identified from an electronic search of MEDLINE, EMBASE and Cochrane Central Register of Controlled Trials from their inception date to 21 November 2018...
April 18, 2024: BMJ Open
https://read.qxmd.com/read/38637127/cavitron-ultrasonic-surgical-aspirator-cusa-compared-with-conventional-pancreatic-transection-in-distal-pancreatectomy-study-protocol-for-the-randomised-controlled-cusa-1-pilot-trial
#42
JOURNAL ARTICLE
Magdalena Holze, Martin Loos, Felix Hüttner, Solveig Tenckhoff, Manuel Feisst, Phillip Knebel, Rosa Klotz, Arianeb Mehrabi, Christoph Michalski, Frank Pianka
BACKGROUND: Postoperative pancreatic fistula (POPF) remains the most common and serious complication after distal pancreatectomy. Many attempts at lowering fistula rates have led to unrewarding insignificant results as still up to 30% of the patients suffer from clinically relevant POPF. Therefore, the development of new innovative methods and procedures is still a cornerstone of current surgical research.The cavitron ultrasonic surgical aspirator (CUSA) device is a well-known ultrasound-based parenchyma transection method, often used in liver and neurosurgery which has not yet been thoroughly investigated in pancreatic surgery, but the first results seem very promising...
April 18, 2024: BMJ Open
https://read.qxmd.com/read/38636985/trainees-are-removed-from-london-surgery-department-after-findings-of-bullying-and-poor-supervision
#43
JOURNAL ARTICLE
Abi Rimmer
No abstract text is available yet for this article.
April 18, 2024: BMJ: British Medical Journal
https://read.qxmd.com/read/38631829/shared-decision-making-for-non-operative-management-versus-operative-management-of-hip-fractures-in-selected-frail-older-adults-with-a-limited-life-expectancy-a-protocol-for-a-nationwide-implementation-study
#44
JOURNAL ARTICLE
Miliaan L Zeelenberg, Paulieke C Oosterwijk, Hanna C Willems, Taco Gosens, Dennis Den Hartog, Pieter Joosse, Sverre A I Loggers, Thomas Mp Nijdam, Ruth E Pel-Littel, Suzanne Polinder, Henk Jan Schuijt, Hugo H Wijnen, Detlef Van der Velde, Esther M M Van Lieshout, Michael H J Verhofstad
BACKGROUND AND PURPOSE: Recent research has highlighted non-operative management (NOM) as a viable alternative for frail older adults with hip fractures in the final phase of life. This study aims to guide Dutch physicians and hospitals nationwide in a standardised implementation of shared decision-making regarding surgery or NOM in selected frail older adults with a hip fracture. METHODS AND ANALYSIS: The patient population for implementation includes frail older adults aged ≥70 years with an acute proximal femoral fracture, nursing home care or a similar level of care elsewhere and at least one additional criterion (ie, malnutrition, severe mobility impairment or ASA≥4)...
April 17, 2024: BMJ Open
https://read.qxmd.com/read/38631815/vallecular-cyst-causing-sleep-disordered-breathing-in-an-older-child
#45
JOURNAL ARTICLE
Dylan J Cooper, Ron Mitzner, Eric A Gantwerker
Consensus-based recommendations are needed to better guide paediatric otolaryngologists in providing standardised care to children with sleep-disordered breathing (SDB). Here we present a unique case of vallecular cyst found during SDB workup in a patient in their middle childhood (6-12 years old). While the patient underwent successful cyst resection, he was noted to have a suspected recurrence 6 months later. Immediately prior to revision excision, repeat awake flexible fibre-optic laryngoscopy revealed complete resolution of the suspected recurrence...
April 17, 2024: BMJ Case Reports
https://read.qxmd.com/read/38627058/fertility-sparing-approach-in-concurrent-gliomatosis-peritonei-and-growing-teratoma-syndrome-in-a-young-woman
#46
JOURNAL ARTICLE
Siti Nawwal Ahmad Nasfy, Habibah Abdul Hamid, Azalea Md Khairuddin, Maryam Kameelah Mohamad Fauzi
Gliomatosis peritonei (GP) and Growing Teratoma Syndrome (GTS) are rare and clinically significant conditions often associated with ovarian teratomas. GP involves the development of benign glial implants on the peritoneal surface, while GTS is characterised by the growth of benign, yet enlarging peritoneal implants following chemotherapy for malignant germ cell tumours. These implants are typically histologically mature teratomas devoid of malignancy. Our report documents a unique case where both GP and GTS manifested in a patient undergoing treatment for an immature ovarian teratoma...
April 16, 2024: BMJ Case Reports
https://read.qxmd.com/read/38627055/acute-diverticulitis-of-the-appendix
#47
JOURNAL ARTICLE
Ahmed Abdelrahim, Yusuf Yusuf, Omer Ali, Haytham Abudeeb
Acute diverticulitis of the appendix (ADA), though uncommon, often presents similarly to acute appendicitis but carries a higher risk of complications such as perforation and malignancy. We report the case of a male patient in his 50s with acute right iliac fossa abdominal pain, diagnosed via CT scan with ADA. Urgent laparoscopic appendicectomy was performed, and the patient was discharged without further issues. This case highlights the importance of promptly identifying and managing such conditions to minimise complications and improve outcomes...
April 16, 2024: BMJ Case Reports
https://read.qxmd.com/read/38627049/megacystis-microcolon-intestinal-hypoperistalsis-syndrome-mmihs-challenges-in-diagnosis-and-management
#48
JOURNAL ARTICLE
Keerthika Murali, Anjan Kumar Dhua
Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is a rare, congenital functional intestinal obstruction, characterised by megacystis (bladder distention in the absence of mechanical obstruction), microcolon and intestinal hypoperistalsis (dysmotility).We are reporting a case of a female child with normal antenatal course who presented with recurrent episodes of abdominal distension since the second day of life and underwent negative exploratory laparotomy on multiple occasions. She also had urinary retention with a grossly distended bladder, requiring drainage by clean intermittent catheterisation...
April 16, 2024: BMJ Case Reports
https://read.qxmd.com/read/38626980/the-impact-of-delayed-diagnosis-and-treatment-due-to-covid-19-on-australian-thyroid-cancer-patients-a-qualitative-interview-study
#49
JOURNAL ARTICLE
Bianka D'souza, Anthony Glover, Claire Bavor, Benjamin Brown, Rachael H Dodd, James C Lee, Jeremy Millar, Julie A Miller, John R Zalcberg, Jonathan Serpell, Liane J Ioannou, Brooke Nickel
OBJECTIVES: The study aims to investigate the perceptions of patients with thyroid cancer on the potential impact of diagnosis and treatment delays during the COVID-19 pandemic. DESIGN: This study involved qualitative semi-structured telephone interviews. The interviews were transcribed verbatim, analysed using the thematic framework analysis method and reported using the Consolidated Criteria for Reporting Qualitative Research. SETTING: Participants in the study were treated and/or managed at hospital sites across New South Wales and Victoria, Australia...
April 15, 2024: BMJ Open
https://read.qxmd.com/read/38626979/protocol-for-an-independent-patient-data-meta-analysis-of-prophylactic-mesh-placement-for-incisional-hernia-prevention-after-abdominal-aortic-aneurysm-surgery-a-collaborative-european-hernia-society-project-i-prevent-aaa
#50
JOURNAL ARTICLE
Rudolf van den Berg, Floris P J den Hartog, Christina Bali, Miltiadis Matsagkas, Paul M Bevis, Jonothan J Earnshaw, Eike S Debus, Susanne Honig, Frederik Berrevoet, Olivier Detry, Cesare Stabilini, Filip Muysoms, Pieter J Tanis
INTRODUCTION: Incisional hernia (IH) is a prevalent and potentially dangerous complication of abdominal surgery, especially in high-risk groups. Mesh reinforcement of the abdominal wall has been studied as a potential intervention to prevent IHs. Randomised controlled trials (RCTs) have demonstrated that prophylactic mesh reinforcement after abdominal surgery, in general, is effective and safe. In patients with abdominal aortic aneurysm (AAA), prophylactic mesh reinforcement after open repair has not yet been recommended in official guidelines, because of relatively small sample sizes in individual trials...
April 16, 2024: BMJ Open
https://read.qxmd.com/read/38626967/the-n-lva-study-effectiveness-and-cost-effectiveness-of-lymphaticovenous-anastomosis-lva-for-patients-with-cancer-who-suffer-from-chronic-peripheral-lymphoedema-study-protocol-of-a-multicentre-randomised-sham-controlled-trial
#51
JOURNAL ARTICLE
Alieske Kleeven, Yasmine M J Jonis, Hanneke Tielemans, Sander van Kuijk, Merel Kimman, René van der Hulst, Dalibor Vasilic, Stefan Hummelink, Shan Shan Qiu
INTRODUCTION: Cancer-related lymphoedema is one of the most debilitating side-effects of cancer treatment with an overall incidence of 15.5%. Patients may suffer from a variety of symptoms, possibly resulting in a diminished health-related quality of life (HRQoL). A microsurgical technique known as lymphaticovenous anastomosis (LVA) might be a promising treatment option. The objective of this study is to evaluate whether LVA is effective and cost-effective compared with sham surgery in improving the HRQoL...
April 15, 2024: BMJ Open
https://read.qxmd.com/read/38626960/functional-therapy-and-adenotonsillectomy-clinical-trial-for-class-ii-malocclusion-fact-ii-protocol-for-a-randomised-controlled-trial
#52
JOURNAL ARTICLE
Feiyang Guo, Chenxing Lv, Bojun Tang, Lizhuo Lin, Chen Zhang, Jie Zheng, Tingting Zhao, Hong He
INTRODUCTION: Class II malocclusion with mandibular retrognathia is a common complication of paediatric obstructive sleep apnoea (OSA), often accompanied by transverse maxillary deficiency. In early orthodontic treatment, a twin block (TB) is a regular functional appliance for correcting this malocclusion. For paediatric OSA, the most common risk factor is adenotonsillar hypertrophy (AHT). Untreated AHT may lead to the persistence and worsening of obstructive sleep-disordered breathing traits, including habitual mouth breathing...
April 16, 2024: BMJ Open
https://read.qxmd.com/read/38626932/efficacy-and-safety-of-first-line-or-second-line-selective-laser-trabeculoplasty-for-normal-tension-glaucoma-a-multicentre-cohort-study
#53
JOURNAL ARTICLE
Koji Nitta, Kae Sugihara, Akiko Narita, Tomoko Naito, Takako Miki, Maki Katai, Shiro Mizoue, Keiji Yoshikawa, Masaki Tanito, Kazuhisa Sugiyama
BACKGROUND/AIMS: This study aimed to investigate and compare the efficacy and safety of first-line and second-line selective laser trabeculoplasty (SLT) in Japanese patients with normal-tension glaucoma (NTG). METHODS: 100 patients with NTG were enrolled in this study. Patients were treated with SLT as a first-line or second-line treatment for NTG. Main outcome measures were intraocular pressure (IOP) reduction rate, outflow pressure improvement rate (ΔOP), success rate at 1 year and complications...
April 15, 2024: BMJ Open Ophthalmology
https://read.qxmd.com/read/38618151/demographics-of-focused-ultrasound-thalamotomy-for-essential-tremor-and-trends-in-deep-brain-stimulation-surgery-after-its-introduction-in-the-usa
#54
JOURNAL ARTICLE
Diwas Gautam, Vishal Venkatraman, Joshua Horns, Lexie Zidanyue Yang, Hui-Jie Lee, Panagiotis Kassavetis, Jumana Alshaikh, Paolo Moretti, Ben Shofty, Shervin Rahimpour
BACKGROUND: Essential tremor (ET) is a movement disorder that affects 4%-5% of adults >65 years. For patients with medically refractory ET, neurosurgical interventions such as deep brain stimulation (DBS) and unilateral MR-guided focused ultrasound thalamotomy (MRgFUS) are available. In this retrospective cohort study, we examined the demographics of patients with ET who have received MRgFUS and evaluated trends in DBS usage in the USA after the introduction of MRgFUS in 2016. METHODS: We used multiple databases to examine the demographics of patients who received DBS and MRgFUS, and trends in DBS...
2024: BMJ neurology open
https://read.qxmd.com/read/38604740/dermatofibrosarcoma-protuberans-of-the-breast
#55
JOURNAL ARTICLE
Muskaan Qadir, Saira Fatima, Safdar Shaikh, Sana Zeeshan
Dermatofibrosarcoma protuberans (DFSP) of the breast is an infrequent soft tissue sarcoma that usually affects young to middle-aged women. Our case report describes a unique occurrence of DFSP of the breast in an adolescent girl, which was initially being managed as a keloid for 2 years under dermatology despite being refractory to treatment. Once the diagnosis of DFSP was confirmed through punch biopsy, our patient underwent surgical excision of the lesion under general anaesthesia. Our patient was at an increased risk of damage to the ductal system due to proximity of the lesion to the nipple-areolar complex, warranting the need for early recognition and treatment...
April 11, 2024: BMJ Case Reports
https://read.qxmd.com/read/38601122/recruitment-and-baseline-characteristics-of-young-adults-at-risk-of-early-onset-knee-osteoarthritis-after-acl-reconstruction-in-the-super-knee-trial
#56
JOURNAL ARTICLE
Adam G Culvenor, Thomas J West, Andrea M Bruder, Mark J Scholes, Christian J Barton, Ewa M Roos, Edwin H G Oei, Steven M McPhail, Richard B Souza, Jusuk Lee, Brooke E Patterson, Michael A Girdwood, Jamon L Couch, Kay M Crossley
OBJECTIVES: The study aims to (1) report the process of recruiting young adults into a secondary knee osteoarthritis prevention randomised controlled trial (RCT) after anterior cruciate ligament reconstruction (ACLR); (2) determine the number of individuals needed to be screened to include one participant (NNS) and (3) report baseline characteristics of randomised participants. METHODS: The SUpervised exercise-therapy and Patient Education Rehabilitation (SUPER)-Knee RCT compares SUPER and minimal intervention for young adults (aged 18-40 years) with ongoing symptoms (ie, mean score of <80/100 from four Knee injury and Osteoarthritis Outcome Score subscales (KOOS4 )) 9-36 months post-ACLR...
2024: BMJ Open Sport & Exercise Medicine
https://read.qxmd.com/read/38599794/transient-severe-haemodynamic-disturbance-during-radical-nephrectomy-a-probable-catecholamine-surge
#57
JOURNAL ARTICLE
Sripriya Ramalingam, Parthasarathy Srinivasan
Catecholamine surge and haemodynamic derangements are normally expected during the surgery for pheochromocytoma and benign functioning adrenal tumours. This male patient in his 50s underwent radical nephrectomy for renal cell carcinoma. The patient had no comorbidities. Three hours into the surgery, during electrocauterisation of the upper pole of the kidney, the patient's blood pressure unexpectedly spiked to 180/110 mm Hg, which was immediately followed by a decrease in heart rate to 35-38 beats/min...
April 10, 2024: BMJ Case Reports
https://read.qxmd.com/read/38599767/reducing-wait-times-and-medical-costs-for-patients-the-physiotherapy-led-spine-triage-and-rehabilitation-star-clinic
#58
JOURNAL ARTICLE
Walter-Soon-Yaw Wong, Cara Min Sun, Hun Yi Koh, Linus Ren Hao Tan, Yilun Huang
The Sengkang General Hospital Orthopaedic Spine Outpatient Service is facing a growing challenge of increasing number of referrals and waiting times, placing a significant burden on the system. Primary care referrals have an average wait time of 61.1 days, with 34.5%f patients waiting longer than 60 days from referral to appointment, to see a spine physician.Back pain is a very common presentation, with the vast majority resolving after conservative management which commonly includes analgesia, physiotherapy and reassurance...
April 10, 2024: BMJ Open Quality
https://read.qxmd.com/read/38596254/project-prevent-a-randomized-controlled-trial-of-preoperative-vaginal-metronidazole-to-decrease-patient-issues-and-infections-after-hysterectomy
#59
JOURNAL ARTICLE
Tana Pradhan, Helen Zhang, Amanda Kadesh, Ama Buskwofie, Sonali Patankar, Sharifa Menon, Timothy Ryntz, Cara L Grimes
OBJECTIVES: To evaluate if vaginal metronidazole for 5 days before hysterectomy decreases postoperative infections and patient issues. DESIGN: This randomized trial compared vaginal metronidazole for 5 days before a scheduled hysterectomy to no intervention. Sample size calculation was based on a 20% difference in issues and infection (30% incidence and 10% in the intervention arm) with 80% power and an alpha error of 0.05 and indicated 62 subjects needed in each arm...
2024: BMJ surgery, interventions, & health technologies
https://read.qxmd.com/read/38594201/ocular-manifestations-suggest-osteogenesis-imperfecta-in-a-previously-undiagnosed-adult-following-polytrauma
#60
JOURNAL ARTICLE
Christopher P Bunting, James F Green
No abstract text is available yet for this article.
April 9, 2024: BMJ Case Reports
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