Zhihao Huang, Zhongqi Zhou, Qiaoyuan Ye, Xiaoyan Li, Tao Wang, Jiaqi Li, Wenjiao Dong, Rui Guo, Yuanlin Ding, Hongman Xue, Haifeng Ding, Cia-Hin Lau
Physicochemical properties of nanoparticles, such as particle size, surface charge, and particle shape, have a significant impact on cell activities. However, the effects of surface functionalization of nanoparticles with small chemical groups on stem cell behavior and function remain understudied. Herein, we incorporated different chemical functional groups (amino, DETA, hydroxyl, phosphate, and sulfonate with charges of +9.5, + 21.7, -14.1, -25.6, and -37.7, respectively) to the surface of inorganic silica nanoparticles...
May 3, 2024: ACS Applied Bio Materials