keyword
https://read.qxmd.com/read/38672974/multidimensional-impact-of-dupilumab-on-chronic-rhinosinusitis-with-nasal-polyps-a-complete-health-technology-assessment-of-clinical-economic-and-non-clinical-domains
#1
JOURNAL ARTICLE
Ignazio La Mantia, Giancarlo Ottaviano, Martina Ragusa, Matteo Trimarchi, Emanuela Foglia, Fabrizio Schettini, Daniele Bellavia, Elena Cantone
Chronic RhinoSinusitis with Nasal Polyps (CRSwNP) represents a condition mainly caused by the type 2 inflammation presence and marked by the existence of polyps within the nasal and paranasal sinuses. The standard of care includes intranasal steroids, additional burst of systemic steroids, if needed, and surgery. However, recurrence is common, especially among patients with comorbid type 2 inflammatory diseases. Recently, biological drugs, addressing the underlying cause of the disease, have been approved in Italy (dupilumab, omalizumab, and mepolizumab)...
March 27, 2024: Journal of Personalized Medicine
https://read.qxmd.com/read/38671385/nanofiber-hydrogel-drug-delivery-system-for-prevention-of-postsurgical-intestinal-adhesion
#2
JOURNAL ARTICLE
Bei Zhao, Panyong Zhu, Hongyu Zhang, Yaoran Gao, Ling Zha, Lin Jin, Lei Zhang
Intestinal adhesion is one of the complications that occurs more frequently after abdominal surgery. Postsurgical intestinal adhesion (PIA) can lead to a series of health problems, including abdominal pain, intestinal obstruction, and female infertility. Currently, hydrogels and nanofibrous films as barriers are often used for preventing PIA formation; however, these kinds of materials have their intrinsic disadvantages. Herein, we developed a dual-structure drug delivery patch consisting of poly lactic- co -glycolic acid (PLGA) nanofibers and a chitosan hydrogel (NHP)...
April 26, 2024: ACS Biomaterials Science & Engineering
https://read.qxmd.com/read/38669783/implementing-change-sustaining-enhanced-recovery-after-surgery-protocols-in-pediatric-surgery-using-iterative-assessments
#3
JOURNAL ARTICLE
Allison R Thompson, Jack P Vernamonti, Paris Rollins, K Elizabeth Speck
INTRODUCTION: While Enhanced Recovery After Surgery (ERAS) protocols are becoming more common in pediatric surgery, there is still little published about protocol compliance and sustainability. METHODS: This is a prospective observational study to evaluate the compliance of an ERAS protocol for pectus repair at a large academic children's hospital. Our primary outcome was overall protocol compliance at 1-y postimplementation of the ERAS protocol. Our comparison group included all pectus repairs for 2 y before protocol implementation...
April 25, 2024: Journal of Surgical Research
https://read.qxmd.com/read/38669473/contemporary-management-of-obesity-a-comparison-of-bariatric-metabolic-surgery-and-novel-incretin-mimetic-drugs
#4
JOURNAL ARTICLE
Abhayjit Singh, Steven E Nissen
The global prevalence of obesity has risen sharply during the past half-century, reaching pandemic proportions and creating a public health crisis. Obesity is a recognized risk factor for the development of diabetes, atherosclerosis, hypertension, hepatic steatosis, and many other cardiometabolic disorders with significant resultant morbidity and mortality. Though treatment of obesity can prevent or slow the progression of these aforementioned illnesses, efforts to help patients achieve reliable and sustainable weight loss have had limited success...
April 26, 2024: Diabetes Technology & Therapeutics
https://read.qxmd.com/read/38669349/correction-of-equinus-deformity-by-ilizarov-frame-using-the-matsushita-method-and-achilles-tendon-lengthening-a-case-report
#5
JOURNAL ARTICLE
Komei Kanetani, Tadashi Kimura, Nori Yamashita, Kazuki Kisamori, Mitsuru Saito, Makoto Kubota
CASE: The patient was an 18-year-old man who had sustained diaphyseal fractures of the left femur and tibia in a traffic accident and underwent surgery at another hospital. A severe left foot equinovarus deformity developed in the early after surgery. The patient's left foot deformity was addressed using unconstrained gradual external fixator correction (the Matsushita method) in combination with soft-tissue contracture through Achilles tendon lengthening and was maintained after removing the external fixation...
April 1, 2024: JBJS Case Connector
https://read.qxmd.com/read/38669104/women-in-facial-plastic-and-reconstructive-surgery-the-state-of-the-academy-and-why-it-matters
#6
JOURNAL ARTICLE
Myriam Loyo, Natalie A Krane, Candace M Waters, Theda C Kontis
Facial plastic and reconstructive surgery has historically been a male-dominated field. It is critical to assess the current state of female representation within our Society to better gauge how we reflect the changing needs of our community and our patients. Although we have made headway in fostering a community ripe for progress, we must continue to create and promote equal opportunities, dissuade microaggressions, address burnout, and capitalize on the innate strengths of our female constituents. With the data presented in this study, we hope to further illuminate the benefits of women engagement in our Academy while recommending sustainable actions to create a culture of allyship...
April 26, 2024: Facial plastic surgery & aesthetic medicine
https://read.qxmd.com/read/38669047/bile-duct-injuries-during-urgent-cholecystectomy-at-a-safety-net-teaching-hospital-attending-experience-and-time-of-day-may-matter
#7
JOURNAL ARTICLE
Chaiss Ugarte, Shannon Zielsdorf, Ramsey Ugarte, Odeya Kagan, Ryan Murphy, Matthew J Martin, Kenji Inaba, Morgan Schellenberg
Background: Bile duct injury (BDI) is one of the most severe complications during cholecystectomy. Early identification of risk factors for BDI may permit risk reduction strategies and inform patient consent. Objective: This study aimed to define patient, provider, and systemic factors associated with BDI; BDI incidence; and short-term outcomes of BDI after urgent cholecystectomy. Methods: Patients who underwent urgent cholecystectomy for acute cholecystitis were retrospectively screened (2020-2022). All patients who sustained BDI were included without exclusions...
April 26, 2024: American Surgeon
https://read.qxmd.com/read/38666178/a-comparative-study-of-key-quality-performance-indicators-in-anesthesia-and-surgery-in-operation-theatre-at-a-tertiary-care-hospital-in-rishikesh
#8
JOURNAL ARTICLE
Bhavna Gupta, Sanjay Agrawal, Anubha Agarwal
BACKGROUND AND AIMS: A Key Performance Indicator (KPI) is a critical metric measuring organizational success or specific activities, reflecting the periodic achievement of operational goals aligned with strategic objectives. MATERIAL AND METHODS: A retrospective cross-sectional study of key quality performance indicators, (CQI-NABH) concerning anesthesia and surgical services was conducted at a tertiary care hospital after taking institutional ethical clearance (AIIMS/IEC/21/150)...
2024: Journal of Anaesthesiology, Clinical Pharmacology
https://read.qxmd.com/read/38666006/novel-chimney-balloon-technique-to-safeguard-cerebral-blood-flow-during-total-endovascular-aortic-arch-repair
#9
JOURNAL ARTICLE
Yu Lun, Han Jiang, Jian Zhang
During endovascular total aortic arch repair by in situ fenestration, extra procedures are needed to sustain cerebral blood flow when targeting all three supra-aortic branches. Recently, our group successfully interposed a chimney balloon between the greater curvature of the aortic arch and an aortic stent to safeguard cerebral blood flow during total endovascular aortic arch repair.
June 2024: Journal of Vascular Surgery Cases and Innovative Techniques
https://read.qxmd.com/read/38661998/what-are-the-predisposing-factors-for-periprosthetic-fractures-following-total-hip-arthroplasty-a-national-inpatient-sample-based-study
#10
JOURNAL ARTICLE
Vibhu Krishnan Viswanathan, Surabhi Subramanian, Varatharaj Mounasamy, Senthil Sambandam
INTRODUCTION: With a progressive rise in the number of total hip arthroplasties (THA) over the past decades, the proportion of patients sustaining peri-prosthetic fractures (PPF) has been substantially increasing. In this context, the need for clearly understanding the factors predisposing patients to PPF following THA and the impact of these adverse complications on the overall healthcare burden cannot be understated. MATERIALS AND METHODS: Based upon the Nationwide Inpatient Sample (NIS) database, the patients who underwent THA in the United States between 2016 and2019 (with ICD-10 CMP code) were identified...
April 25, 2024: Archives of Orthopaedic and Trauma Surgery
https://read.qxmd.com/read/38660025/emergency-resuscitative-thoracotomy-in-severe-trauma-analysis-of-the-nation-wide-registry-data-in-japan
#11
JOURNAL ARTICLE
Hiromu Okano, Takero Terayama, Hiroshi Okamoto, Tsutomu Yamazaki
AIM: Emergency resuscitative thoracotomy is a potentially lifesaving procedure for patients with cardiac pulmonary arrest and profound circulatory failure resulting from a severe injury. However, survival rate post-emergency resuscitative thoracotomy shows considerable variation, with many studies constrained by limited sample sizes and ambiguous criteria for inclusion. Herein, we assessed the outcomes of emergency resuscitative thoracotomy and identified predictors of futility using Japan Trauma Data Bank data...
2024: Acute Medicine & Surgery
https://read.qxmd.com/read/38658057/physiotherapy-for-continence-and-muscle-function-in-prostatectomy-a-randomised-controlled-trial
#12
JOURNAL ARTICLE
Mifuka Ouchi, Takeya Kitta, Hiroki Chiba, Madoka Higuchi, Yui Abe-Takahashi, Mio Togo, Naohisa Kusakabe, Sachiyo Murai, Hiroshi Kikuchi, Ryuji Matsumoto, Takahiro Osawa, Takashige Abe, Nobuo Shinohara
OBJECTIVE: To assess the effectiveness of pre- and postoperative supervised pelvic floor muscle training (PFMT) on the recovery of continence and pelvic floor muscle (PFM) function after robot-assisted laparoscopic radical prostatectomy (RARP). PATIENTS AND METHODS: We carried out a single-blind randomised controlled trial involving 54 male patients scheduled to undergo RARP. The intervention group started supervised PFMT 2 months before RARP and continued for 12 months after surgery with a physiotherapist...
April 24, 2024: BJU International
https://read.qxmd.com/read/38657667/the-evolution-of-my-extended-smas-biplanar-deep-plane-facelift-to-a-composite-tissue-deep-plane-face-and-neck-lift-similarities-and-differences
#13
JOURNAL ARTICLE
Stephen W Perkins, Alexander Caniglia
Dr. Stephen Perkins, a seasoned facial plastic surgeon, presents his refined techniques in facelift surgery developed over four decades of practice. His evolution from traditional methods to the current composite tissue deep plane facelift is elucidated. His composite tissue deep plane facelift involves meticulous dissection and repositioning of the superficial musculoaponeurotic system (SMAS) and platysma in the deep plane, as well as incorporating his innovative "Perkins' Kelly clamp anterior platysmaplasty...
April 24, 2024: Facial Plastic Surgery: FPS
https://read.qxmd.com/read/38656340/long-gap-esophageal-atresia-gastric-transposition-or-esophageal-lengthening-with-delayed-primary-anastomosis-a-systematic-review
#14
REVIEW
Omar Nasher, Nigel J Hall, Rajnikant Mehta, Yousef El-Gohary, Marian Knight
PURPOSE: This study aims to evaluate different surgical approaches to long-gap esophageal atresia (LGEA) with or without tracheoesophageal fistula (TEF) is unclear. METHODS: A systematic literature review was done comparing gastric transposition versus esophageal lengthening with delayed primary anastomosis in infants with LGEA+/-TEF. The primary outcome was time to full oral feeds. Secondary outcomes were time to full enteric feeds, need for further surgery, growth, mortality, and postoperative adverse events...
April 24, 2024: Pediatric Surgery International
https://read.qxmd.com/read/38655121/harnessing-the-power-of-artificial-intelligence-and-robotics-impact-on-attaining-competitive-advantage-for-sustainable-development-in-hospitals-with-conclusions-for-future-research-approaches
#15
JOURNAL ARTICLE
Narasingappa Pavithra, Noor Afza
Artificial intelligence (AI) and robotics have emerged as game-changing technologies with the potential to revolutionize the healthcare industry. In the context of hospitals, their integration holds the promise of not only improving patient care but also driving competitive advantage and fostering sustainable development. This review paper aims to explore and evaluate the impact of AI and robotics applications on attaining competitive advantage and promoting sustainable development in hospitals, examines the current landscape of AI and robotics adoption in healthcare settings and delve into their specific applications within hospitals, including AI-assisted diagnosis, robotic surgery, patient monitoring, and data analytics...
2024: GMS Hygiene and Infection Control
https://read.qxmd.com/read/38655116/spine-injuries-sustained-after-falls-while-crossing-the-u-s-mexico-border
#16
JOURNAL ARTICLE
Hannah R Riva, Michael M Polmear, Cyrena Petersen, June Y Guillet, Taylor M Yong, Adam H Adler, Rajiv Rajani, Vishwajeet Singh, David Chin Sing Wang
This study is to report the demographics, incidence, and patterns of spinal injuries associated with border crossings resulting from a fall from a significant height. A retrospective cohort study was performed at a Level I trauma center from January 2016 to December 2021 to identify all patients who fell from a significant height while traversing the U.S.-Mexico border and were subsequently admitted. A total of 448 patients were identified. Of the 448 patients, 117 (26.2%) had spine injuries and 39 (33.3%) underwent operative fixation...
2024: Neurotrauma reports
https://read.qxmd.com/read/38652817/a-ropivacaine-eluting-poly-lactide-co-caprolactone-wound-dressing-provided-enhanced-analgesia-in-partial-thickness-porcine-injuries
#17
JOURNAL ARTICLE
Stefan Niederauer, Mike Beeman, Andrew Cleveland, Susan Wojtalewicz, Sierra Erickson, Christopher A Reilly, Joseph E Rower, Caroline Garrett, Candace Floyd, Jill Shea, Jay Agarwal, Caleb Lade, Brett Davis
BACKGROUND: Partial-thickness skin wounds are some of the most painful injuries due to large areas of exposed nerve endings. These injuries often require systemic opioid treatments to manage pain adequately. However, in 2021 alone, the CDC reported nearly 17,000 prescription opioid-related deaths in the USA, highlighting the ongoing need for non-opioid treatment strategies. In this manuscript, we developed a novel single-application ropivacaine-eluting primary wound dressing that could provide sustained ropivacaine delivery to partial-thickness wounds and assessed its in vivo feasibility for prolonged non-opioid analgesia...
April 23, 2024: Plastic and Reconstructive Surgery
https://read.qxmd.com/read/38652655/career-trajectory-after-general-surgery-residency-do-academic-program-graduates-pursue-academic-surgery
#18
JOURNAL ARTICLE
Allen Green, Elijah R Sommer, Max R Johnson, Hector Gonzalez, Twan Sia, David A Spain, Jeff Choi
OBJECTIVE: Determine the proportion of contemporary US academic general surgery residency program graduates who pursue academic careers and identify factors associated with pursuing academic careers. SUMMARY BACKGROUND DATA: Many academic residency programs aim to cultivate academic surgeons, yet the proportion of contemporary graduates who choose academic careers is unclear. The potential determinants that affect graduates' decisions to pursue academic careers remain underexplored...
April 23, 2024: Annals of Surgery
https://read.qxmd.com/read/38652257/mesenteric-sparing-approach-for-advanced-nodal-extent-in-small-intestinal-neuroendocrine-tumors-is-there-a-limit-to-the-vascular-resection-in-order-to-avoid-creating-a-short-small-bowel-syndrome-an-anatomic-research-study
#19
JOURNAL ARTICLE
Paul Bufacchi, Mathys Gomes-Jorge, Thomas Walter, Gilles Poncet, Arnaud Pasquer
PURPOSE: By selectively perfusing the first three jejunal arteries (JA), we aim to assess the individual perfusion length of small bowel (SB) and its impact on nodal resection in stage III-up small-intestinal neuroendocrine tumors (SI-NET). METHODS: Our anatomical research protocol implies a midline laparotomy and three measures of the SB length. We then perform a classical anterior approach of the superior mesenteric vessels. We carry on with the complete dissection and checking of the superior mesenteric artery (SMA) in order to identify the first three JA...
April 23, 2024: Surgical and Radiologic Anatomy: SRA
https://read.qxmd.com/read/38652245/long-stem-revision-versus-short-stem-revision-with-plate-osteosynthesis-for-vancouver-type-b2-periprosthetic-femoral-fracture-a-comparative-study-of-eighty-five-cases
#20
JOURNAL ARTICLE
Jian-Jiun Chen, Shih-Hsin Hung, Jia-You Liou, Wen-Chieh Chang, Kuei-Hsiang Hsu, Yu-Pin Su, Fang-Yao Chiu, Ming-Fai Cheng
PURPOSE: Periprosthetic femoral fractures (PPFs) around the hip are challenging complications in orthopaedic surgery, particularly Vancouver type B2 (VTB2) fractures. The surgical management of these fractures is crucial and depends on various factors. Cementless short taper stem with plate osteosynthesis is an alternative surgical technique. This study aims to compare the outcomes of this surgical technique with revision arthroplasty (RA) with long stem in the treatment of VTB2 PPFs...
April 23, 2024: International Orthopaedics
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