Avrom S Caplan, Gabrielle C Todd, YanChun Zhu, Michelle Sikora, Christine C Akoh, Jeannette Jakus, Shari R Lipner, Kayla Babbush, Karen P Acker, Ayana E Morales, Rebecca M Marrero Rolón, Lars F Westblade, Maira Fonseca, Abigail Cline, Jeremy A W Gold, Shawn R Lockhart, Dallas J Smith, Tom Chiller, William G Greendyke, Swati R Manjari, Nilesh K Banavali, Sudha Chaturvedi
IMPORTANCE: Trichophyton indotineae is an emerging dermatophyte causing outbreaks of extensive tinea infections often unresponsive to terbinafine. This species has been detected worldwide and in multiple US states, yet detailed US data on infections with T indotineae are sparse and could improve treatment practices and medical understanding of transmission. OBJECTIVE: To correlate clinical features of T indotineae infections with in vitro antifungal susceptibility testing results, squalene epoxidase gene sequence variations, and isolate relatedness using whole-genome sequencing...
May 15, 2024: JAMA Dermatology