Ashraf H F Abd El-Wahab, Rita M Borik, Al-Anood M Al-Dies, Ahmed M Fouda, Hany M Mohamed, Raafat A El-Eisawy, Mohamed H Sharaf, Abdullah Y A Alzahrani, Ahmed A Elhenawy, Ahmed M El-Agrody
The process of creating a series of 3-amino-1-aryl-8-methoxy-1H-benzo[f]chromene-2-carbonitriles (4a-q) involved reacting 6-methoxynaphthalen-2-ol (1), the appropriate aromatic aldehydes (2a-q), and malononitrile (3) in an absolute ethanol/piperidine solution under Ultrasonic irradiation. However, the attempt to create 3-amino-1-aryl-1H-benzo[f]chromene-2,8-dicarbonitrile (6a, d, e) was unsuccessful when 6-cyanonaphthalen-2-ol (5) was stirred at room temperature, reflux, Microwave irradiation, or Ultrasonic irradiation...
April 29, 2024: Scientific Reports