Yanjing Huang, Runan Hu, Zhuo Liu, Yuli Geng, Fan Li, Yufan Song, Wenwen Ma, Haoxu Dong, Lijun Xu, Mingmin Zhang, Kunkun Song
BACKGROUND: Premature ovarian insufficiency (POI) is a tricky puzzle in the field of female reproductive medicine. Bushen Huoxue recipe (BHR), a traditional Chinese medicine compound based on the combination of kidney-tonifying and blood-activating functions, has shown excellent efficacy in improving female irregular menstruation, POI, and infertility. However, the potential mechanism of BHR in POI treatment has not yet been elucidated. Bone marrow mesenchymal stem cells (BMSCs), a type of pluripotent stem cells, have received increasing attention for their significant role in improving ovarian function and restoring fertility in women with POI...
April 24, 2024: Phytomedicine