Ophélie Coiffier, Pasquale Tondo, Marie Joyeux-Faure, Renaud Tamisier, Khier Amrani, Jean-Claude Cornu, Robin Terrail, Christian Caussé, Sebastien Bailly, Jean-Louis Pépin
OBJECTIVE/BACKGROUND: Chronic obstructive pulmonary disease (COPD), obstructive sleep apnea (OSA) and their comorbid association called Overlap Syndrome (OS) are frequent chronic diseases with high individual and societal burdens. Precise descriptions of the respective symptoms, comorbidities, and medications associated with these three conditions are lacking. We used a multidimensional phenotyping approach to identify relevant phenotypes characterizing these 3 disorders. PATIENTS/METHODS: 308 patients with OSA, COPD and OS were prospectively assessed using a combination of body shape measurements and multidimensional questionnaires evaluating sleep, fatigue, depression and respiratory symptoms...
May 3, 2024: Sleep Medicine