keyword
https://read.qxmd.com/read/38794790/gross-morphologic-features-of-surgical-specimen-in-rectal-cancer-patients-with-pathological-complete-response-following-neoadjuvant-chemoradiotherapy-a-cross-sectional-study
#21
JOURNAL ARTICLE
Amir Reza Fazeli, Kiana Tadbir Vajargah, Mohammad Sadegh Fazeli, Behnam Behboudi, Seyed Mohsen Ahmadi-Tafti, Alireza Kazemeini, Amir Keshvari, Mohammad Reza Keramati
BACKGROUND: pathological complete response (pCR) is achieved in 10%-30% of rectal cancer patients following neoadjuvant chemoradiotherapy and surgery. Residual mucosal abnormalities, which make patients ineligible for nonoperative management, may not be an accurate indicator of the pCR. The purpose of this study was to report the gross findings of rectal cancer patients with pathological complete responses. METHODS: This study was conducted at Tehran University of Medical Sciences, Tehran, Iran...
May 24, 2024: World Journal of Surgery
https://read.qxmd.com/read/38789169/achilles-tendon-rupture
#22
REVIEW
Mark Bullock, Zachary Pierson
There are many high-level studies comparing nonoperative treatment, open repair, and minimally invasive repair for Achilles tendon ruptures. This article summarizes the most up-to-date literature comparing these treatment options. The authors' preferred protocol for nonoperative treatment is discussed. Preferred techniques for open repair and chronic Achilles repair are discussed with reference to the literature.
July 2024: Clinics in Podiatric Medicine and Surgery
https://read.qxmd.com/read/38789168/current-concepts-in-ankle-fracture-management
#23
REVIEW
Sandeep Patel, Shontal Behan Dionisopoulos
Ankle fractures are one of the more common musculoskeletal injuries that are treated by foot and ankle specialists. A thorough understanding of managing these injuries requires the ability to differentiate between stable and unstable fractures. The current literature supports the nonoperative management of stable Weber B ankle fractures, whereas unstable fractures have much better outcomes with surgical intervention. Specifically, we review the fixation strategies for the lateral, medial, and posterior malleolar fractures respectively...
July 2024: Clinics in Podiatric Medicine and Surgery
https://read.qxmd.com/read/38789160/fifth-metatarsal-fractures
#24
REVIEW
Michael Keller, Brett Saltrick, Logan Gull, Brian Reade
Fifth metatarsal features are the most common fractures in the foot. They have a long history that has resulted in many classification systems and little consensus on appropriate treatment. Although there is some agreement among experts, there are also many questions yet to be answered. There is a general consensus that dancer's fractures and zone 1 fractures can generally be treated nonoperatively. There is much more debate about zone 2 and 3 fractures and appropriate treatment guidelines. The authors review the current literature and give the recommendation for treatment based on their experience in a community-based private practice...
July 2024: Clinics in Podiatric Medicine and Surgery
https://read.qxmd.com/read/38789159/metatarsal-fractures
#25
REVIEW
Samuel A Straus, James Daniel Henry, John Randolph Clements
Metatarsal fractures are some of the most common fractures reported in the human body. Recent advances in surgical techniques and fixation have helped facilitate healing and improved outcomes for our patients. The treatment goals of metatarsal fractures are to maintain the metatarsal parabola, sagittal position of the metatarsal heads, and a congruent metatarsophalangeal joint. Most of these injuries can be treated nonoperatively, but displaced fractures require surgical intervention to preserve normal gait biomechanics...
July 2024: Clinics in Podiatric Medicine and Surgery
https://read.qxmd.com/read/38788469/benefits-of-rib-fixation-utilizing-low-cost-materials-a-randomized-pilot-trial
#26
JOURNAL ARTICLE
Joses Dany James, Narendra Choudhary, Dinesh Bagaria, Jogendra Boddeda, Abhinav Kumar, Pratyusha Priyadarshini, Biplab Mishra, Sushma Sagar, Subodh Kumar, Amit Gupta
INTRODUCTION: Surgical stabilization of rib fractures (SSRF) using standard rib plating systems has become a norm in developed countries. However, the procedure has not garnered much interest in low-middle-income countries, primarily because of the cost. METHODS: This was a single-center pilot randomized trial. Patients with severe rib fractures were randomized into two groups: SSRF and nonoperative management. SSRF arm patients underwent surgical fixation in addition to the tenets of nonoperative management...
May 23, 2024: Journal of Surgical Research
https://read.qxmd.com/read/38787554/adaptation-of-the-risk-analysis-index-for-frailty-assessment-using-diagnostic-codes
#27
JOURNAL ARTICLE
Alis J Dicpinigaitis, Yekaterina Khamzina, Daniel E Hall, Hasan Nassereldine, Jason Kennedy, Christopher W Seymour, Meic Schmidt, Katherine M Reitz, Christian A Bowers
IMPORTANCE: Frailty is associated with adverse outcomes after even minor physiologic stressors. The validated Risk Analysis Index (RAI) quantifies frailty; however, existing methods limit application to in-person interview (clinical RAI) and quality improvement datasets (administrative RAI). OBJECTIVE: To expand the utility of the RAI utility to available International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) administrative data, using the National Inpatient Sample (NIS)...
May 1, 2024: JAMA Network Open
https://read.qxmd.com/read/38787286/selective-nonoperative-versus-operative-management-of-liver-gunshot-injuries-a-retrospective-cohort-study
#28
JOURNAL ARTICLE
R R Dalcin, Ytm Petrillo, Lac Alves, M K Fonseca, A S Almeida, C O Corso
INTRODUCTION: Experience accumulated over the last decades suggests nonoperative management (NOM) of civilian gunshot liver injuries can be safely applied in selected cases. This study aims to compare the outcomes of selective NOM versus operative management (OM) of patients sustaining gunshot wounds (GSW) to the liver. METHODS: A registry-based retrospective cohort analysis was performed for the period of 2008 to 2016 in a Brazilian trauma referral. Patients aged 16-80 years sustaining civilian GSW to right-sided abdominal quadrants and liver injury were included...
May 24, 2024: Annals of the Royal College of Surgeons of England
https://read.qxmd.com/read/38782510/surgical-outcomes-in-charcot-arthropathy
#29
REVIEW
William C Skinner, Naveen Pattisapu, Jane Yeoh, Benjamin J Grear, David R Richardson, Garnett A Murphy, Clayton C Bettin
Treatment of Charcot neuroarthropathy (CN) of the foot and ankle remains challenging for both patients and surgeons. Nonoperative treatment with cast/orthosis immobilization has long been the mainstay of treatment, but surgical intervention has gained interest to improve poor long-term outcomes. A review of existing data on the operative management of CN demonstrates the potential benefits but also the continued risks associated with treatment. Additionally, a retrospective review of cohorts managed with limited surgical interventions (wound debridements, exostectomies, and other surgical procedures) compared to reconstructive procedures provides additional insight into the surgical management of CN...
July 2024: Orthopedic Clinics of North America
https://read.qxmd.com/read/38782409/palliative-intervention-for-malignant-bowel-obstruction-comes-at-a-cost-a-national-inpatient-study
#30
JOURNAL ARTICLE
Beatrice J Sun, Lakshika Tennakoon, David A Spain, Byrne Lee
Background: Malignant bowel obstruction (MBO) due to peritoneal carcinomatosis (PC) is associated with poor outcomes. Optimal management for palliation remains unclear. This study aims to characterize nonoperative, procedural, and operative management strategies for MBO and evaluate its association with mortality and cost. Materials and Methods: ICD-10 coding identified patient admissions from the 2018 to 2019 National Inpatient Sample (NIS) for MBO with PC from gastrointestinal or ovarian primary cancers. Management was categorized as nonoperative, procedural, or surgical...
May 23, 2024: American Surgeon
https://read.qxmd.com/read/38770924/national-analysis-of-clinical-outcomes-associated-with-cirrhotic-blunt-trauma-patients-undergoing-emergency-laparotomy-versus-non-operative-management-a-propensity-case-matched-analysis
#31
JOURNAL ARTICLE
Adel Elkbuli, Nikita Bundschu, Hazem Nasef, Brian Chin, David L McClure, Heather X Rhodes-Lyons
INTRODUCTION: This study aims to evaluate clinical outcomes among severely injured trauma patients presenting with isolated blunt abdominal solid organ injuries with a pre-diagnosis of liver cirrhosis (LC) undergoing emergency laparotomy vs nonoperative management (NOM). METHODS: This retrospective cohort study utilized the American College of Surgeons Trauma Quality Program Participant Use File (ACS-TQIP-PUF) dataset from 2017 to 2021. Adults (≥18 years) with a pre-existing diagnosis of LC who presented with severe blunt (ISS ≥ 16) isolated solid organ abdominal injuries and underwent laparotomy or NOM were included...
May 21, 2024: American Surgeon
https://read.qxmd.com/read/38770447/comparing-the-clinical-and-radiographic-outcomes-of-humeral-shaft-fractures-by-treatment-type
#32
JOURNAL ARTICLE
Chrystina L James, Jager Haan, Susan G Wager, Yash Hegde, Trevor D Wolterink, Stephanie Muh
PURPOSE: Humeral shaft fractures are common orthopedic injuries, representing 1-5% of all fractures. There is conflicting literature regarding the superiority of operative versus nonoperative treatment of these fractures. The purpose of this study was to examine functional outcomes and time to radiographic union in humeral shaft fractures with the hypothesis that both would be improved in patients treated operatively relative to those treated nonoperatively. METHODS: This retrospective cohort study examined patients with humeral shaft fractures treated at a single large healthcare system between 2010 and 2020...
April 2024: Curēus
https://read.qxmd.com/read/38769789/survival-predictive-nomograms-for-non-surgical-brain-metastases-patients-from-non-small-cell-lung-cancer-receiving-radiotherapy-a-population-based-study
#33
JOURNAL ARTICLE
Peng Li, Jie Luo, Zilong Zheng, Lu Meng, Anqi Zhang, Wei Cao, Xiaomei Gong
OBJECTIVE: A high number of Non-Small Cell Lung Cancer (NSCLC) patients with brain metastasis who have not had surgery often have a negative outlook. Radiotherapy remains a most common and effective method. Nomograms were developed to forecast the cancer-specific survival (CSS) and overall survival (OS) in NSCLC individuals with nonoperative brain metastases who underwent radiotherapy. METHODS: Information was gathered from the Surveillance, Epidemiology, and End Results (SEER) database about patients diagnosed with NSCLC who had brain metastases not suitable for surgery...
2024: Cancer Control: Journal of the Moffitt Cancer Center
https://read.qxmd.com/read/38768426/evolving-standards-of-care-in-the-management-of-localized-colorectal-cancer
#34
REVIEW
Benjamin A Weinberg, Paul E Sackstein, James Yu, Richard D Kim, Joshua Sommovilla, Sudha R Amarnath, Smitha S Krishnamurthi
The treatment of patients with localized rectal cancer is complex and requires input from a multidisciplinary team. Baseline local staging and mismatch repair protein testing are vital to develop individualized treatment plans. There are multiple options in terms of treatment modalities and sequencing, including transanal excision, short-course radiation, long-course chemoradiation, chemotherapy doublet or triplet, nonoperative management, and immune checkpoint blockade for patients with mismatch repair deficient tumors...
June 2024: American Society of Clinical Oncology Educational Book
https://read.qxmd.com/read/38767385/surgical-management-of-persistent-or-new-symptoms-after-hiatal-hernia-repair
#35
JOURNAL ARTICLE
Raul Caso, Puja G Khaitan
Following a hiatal hernia repair, patients can present with recurrent or new symptoms. Symptoms can occur anywhere from weeks to years after surgery. These may include recurrent reflux, dysphagia, regurgitation, weight loss, or deteriorating quality of life. While nonoperative management can be pursued in some patients, reoperation may be the only option in select patients. A thorough preoperative workup, including a repeat esophagram, upper endoscopy, +/- chest computed tomography (CT) scan, manometry, pH probe, and/or gastric emptying study, is warranted to better understand the pathophysiology of the presenting symptoms...
May 3, 2024: Journal of Visualized Experiments: JoVE
https://read.qxmd.com/read/38767222/operative-versus-non-operative-management-of-isolated-ulnar-diaphyseal-fractures-opera-ulna-protocol-for-a-randomized-controlled-trial
#36
JOURNAL ARTICLE
Prism Schneider, Sohail Bajammal, Ross Leighton, Kelcie Witges, Kimberly Rondeau, Paul Duffy
AIMS: Isolated fractures of the ulnar diaphysis are uncommon, occurring at a rate of 0.02 to 0.04 per 1,000 cases. Despite their infrequency, these fractures commonly give rise to complications, such as nonunion, limited forearm pronation and supination, restricted elbow range of motion, radioulnar synostosis, and prolonged pain. Treatment options for this injury remain a topic of debate, with limited research available and no consensus on the optimal approach. Therefore, this trial aims to compare clinical, radiological, and functional outcomes of two treatment methods: open reduction and internal fixation (ORIF) versus nonoperative treatment in patients with isolated ulnar diaphyseal fractures...
May 20, 2024: Bone & joint open
https://read.qxmd.com/read/38765339/outcomes-of-nonoperative-management-of-penetrating-abdominal-trauma-injury-a-retrospective-study
#37
JOURNAL ARTICLE
Yasser A Obadiel, Ali Albrashi, Noman Allahabi, Mutahhar Sharafaddeen, Faisal Ahmed
BACKGROUND: The treatment of penetrating abdominal injuries has changed in recent years with more focus on "nonoperative management" (NOM) to avoid unnecessary laparotomies while identifying injuries early. Although the NOM approach is widely used for stab wounds, its effectiveness in managing abdominal gunshot wounds is controversial. NOM of penetrating abdominal injuries is becoming more dependent on hemodynamic stability and improved noninvasive radiological interventions. The role of NOM is significantly underreported and underestimated in developing countries, particularly in fragile and conflict-affected states such as Yemen...
April 2024: Curēus
https://read.qxmd.com/read/38761237/acetabular-fractures-in-geriatric-patients-epidemiology-pathomechanism-classification-and-treatment-options
#38
JOURNAL ARTICLE
Dietmar Krappinger, Thomas Freude, Fabian Stuby, Richard A Lindtner
The incidence of geriatric acetabular fractures has shown a sharp increase in the last decades. The majority of patients are male, which is different to other osteoporotic fractures. The typical pathomechanism generally differs from acetabular fractures in young patients regarding both the direction and the amount of force transmission to the acetabulum via the femoral head. Geriatric fractures very frequently involve anterior structures of the acetabulum, while the posterior wall is less frequently involved...
May 18, 2024: Archives of Orthopaedic and Trauma Surgery
https://read.qxmd.com/read/38759240/ongoing-decision-making-dilemma-for-treatment-of-de-novo-spinal-infections-a-comparison-of-the-spinal-infection-treatment-evaluation-score-with-the-spinal-instability-spondylodiscitis-score-and-spine-instability-neoplastic-score
#39
JOURNAL ARTICLE
Jonathan Pluemer, Yevgeniy Freyvert, Nathan Pratt, Periklis Godolias, Hamzah A Al-Awadi, Mitchell H Young, Amir Abdul-Jabbar, Thomas A Schildhauer, Jens R Chapman, Rod J Oskouian
OBJECTIVE: De novo spinal infections are an increasing medical problem. The decision-making for surgical or nonsurgical treatment for de novo spinal infections is often a non-evidence-based process and commonly a case-by-case decision by single physicians. A scoring system based on the latest evidence might help improve the decision-making process compared with other purely radiology-based scoring systems or the judgment of a single senior physician. METHODS: Patients older than 18 years with an infection of the spine who underwent nonsurgical or surgical treatment between 2019 and 2021 were identified...
May 17, 2024: Journal of Neurosurgery. Spine
https://read.qxmd.com/read/38758928/transiliac-shortening-osteotomy-to-treat-ischial-pressure-injury-due-to-fixed-pelvic-obliquity-a-case-report
#40
JOURNAL ARTICLE
Richard M Schwend, Brandon T Nguyen, McKenna C Noe, John T Anderson, Shao Jiang
CASE: A 17-year-old adolescent boy with Gross Motor Function Classification System 5 cerebral palsy and neuromuscular scoliosis underwent posterior spinal fusion and segmental spinal instrumentation from T3 to the pelvis. He developed a right ischial pressure injury a few months postoperatively, which persisted despite nonoperative measures. He subsequently underwent an ipsilateral transiliac-shortening osteotomy 16 months after spinal surgery to treat his residual pelvic obliquity and the ischial pressure injury, which healed completely...
April 1, 2024: JBJS Case Connector
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