Binswanger

Background and Purpose: The clinical diagnosis of Binswanger's disease (BD), a chronic progressive form of subcortical vascular dementia, remains challenging. 3D pseudo-continuous arterial-spin-labeling (pcASL) and diffusion kurtosis imaging (DKI) can quantitatively reveal the microcirculation changes and heterogeneity of white matter (WM), respectively. We thus aimed to determine the diagnostic value of the combined 3D-pcASL and DKI in BD. Materials and Methods: A total of 35 patients with BD and 33 healthy controls underwent 3D-ASL and DKI experiments...

BACKGROUND AND AIMS: Buprenorphine is an effective medication for opioid use disorder that reduces mortality; however, many patients are not retained in buprenorphine treatment, and an optimal length of treatment after which patients can safely discontinue treatment has not been identified. This study measured the association between buprenorphine treatment duration and all-cause mortality among patients who discontinued treatment. Secondary objectives were to measure the association between treatment duration and drug overdose and opioid-related overdoses...

OBJECTIVE: The authors sought to characterize the 3-year prevalence of mental disorders and nonnicotine substance use disorders among male and female primary care patients with documented opioid use disorder across large U.S. health systems. METHODS: This retrospective study used 2014-2016 data from patients ages ≥16 years in six health systems. Diagnoses were obtained from electronic health records or claims data; opioid use disorder treatment with buprenorphine or injectable extended-release naltrexone was determined through prescription and procedure data...

Objective: Develop and implement a prescription opioid registry in 10 diverse health systems across the US and describe trends in prescribed opioids between 2012 and 2018. Materials and Methods: Using electronic health record and claims data, we identified patients who had an outpatient fill for any prescription opioid, and/or an opioid use disorder diagnosis, between January 1, 2012 and December 31, 2018. The registry contains distributed files of prescription opioids, benzodiazepines and other select medications, opioid antagonists, clinical diagnoses, procedures, health services utilization, and health plan membership...

Importance: Patients who use cannabis for medical reasons may benefit from discussions with clinicians about health risks of cannabis and evidence-based treatment alternatives. However, little is known about the prevalence of medical cannabis use in primary care and how often it is documented in patient electronic health records (EHR). Objective: To estimate the primary care prevalence of medical cannabis use according to confidential patient survey and to compare the prevalence of medical cannabis use documented in the EHR with patient report...

INTRODUCTION: Cognitive function is an important factor that affects functional recovery after hip fracture (HipFx) surgery. The literature on the pathophysiology of dementia in HipFx patients is scarce. We performed a differential diagnosis of dementia in HipFx patients using clinical and brain MRI findings. METHODS: This is a prospective study in which brain MRI was evaluated for patients with HipFx for research purposes. One-hundred-and-five HipFx patients (85 females and 20 males) who underwent surgery and were subsequently able to undergo brain MRI at our hospital were evaluated...

BACKGROUND: Although naloxone prevents opioid overdose deaths, few patients prescribed opioids receive naloxone, limiting its effectiveness in real-world settings. Barriers to naloxone prescribing include concerns that naloxone could increase risk behavior and limited time to provide necessary patient education. OBJECTIVE: To determine whether pharmacy-based naloxone co-dispensing affected opioid risk behavior. Secondary objectives were to assess if co-dispensing increased naloxone acquisition, increased patient knowledge about naloxone administration, and affected opioid dose and other substance use...

BACKGROUND: During differential diagnosis of various types of dementia, there are certain difficulties in determining disorders of cerebral angioarchitectonics and microcirculation. We present the features of cerebrovascular and microcirculatory disorders in Alzheimer's disease (AD) and Binswanger's disease (BD). METHOD: The research included 120 patients, of whom: (1) 93 aged 34-80 (average age 67.5), 32 (34.40%) men and 61 (65.59%) women, suffering from AD. According to dementia severity, the patients were subdivided: (TDR-0) - 10, (TDR-1) - 29, (TDR-2) - 36, (TDR-3) - 18 people; (2) 27 aged 58-81 (average age 78), 17 (62...

Background Studies have consistently found high rates of unintended pregnancy among women with opioid use disorder (OUD). Few interventions have been developed to specifically engage and address the family planning (FP) needs of women in substance use disorder treatment. Objectives : Our goal was to collect formative qualitative data to identify the FP experiences, needs and service preferences of women receiving medications for OUD and to use these data to develop a FP education and navigation intervention that could be tested in diverse, resource-limited treatment settings...

No abstract text is available yet for this article.

BACKGROUND: Hospitalizations related to opioid use disorder (OUD) are rising. Addiction consultation services (ACS) increasingly provide OUD treatment to hospitalized patients, but barriers to initiating and continuing medications for OUD remain. We examined facilitators and barriers to hospital-based OUD treatment initiation and continuation from the perspective of patients and healthcare workers in the context of an ACS. METHODS: In this qualitative study, we sought input using key informant interviews and focus groups from patients who received care from an ACS during their hospitalization and from hospitalists, pharmacists, social workers, and nurses who work in the hospital setting...

BACKGROUND: The research investigates stimulation of cerebral angiogenesis and neurogenesis with Transcatheter Intracerebral Laser Photobiomodulation Therapy (PBMT) in patients with dementia with Alzheimer's disease (AD) and Binswanger's disease (BD). MATERIALS & METHODS: Examined 120 patients suffering from dementia. Accomplished: CDR assessment, Tomography Dementia Rating scale (TDR), MMSE, cerebral CT, MRI, SG, rheoencephalography (REG), cerebral MUGA. We chose 48 patients suffering from AD aged 34-80 (mean age 67...

This article presents an introduction to Ludwig Binswanger's Comments on Hermann Rorschach's Psychodiagnostik , published in the International Journal of Psychoanalysis in 1923, after Rorschach's death in 1922. Binswanger, one of the most distinguished psychiatrists of the twentieth century and a close professional colleague and compatriot in the Swiss Psychiatric and Psychoanalytic Societies, was blazing new trails by incorporating turn-of-the-century phenomenology and experimental psychology into Swiss psychiatry...

Medications for opioid use disorder (MOUD) are clinically effective at treating OUD among legal-involved populations. However, research shows that legal-involved veterans who receive care through the VHA have lower rates of MOUD use compared to non-legal-involved veterans. Education may be a key factor in intervention strategies to improve MOUD access. This study was a national survey of VHA staff to identify barriers to and facilitators of MOUD, as well as MOUD-related education needs for VHA staff, community partners, criminal justice partners, and legal-involved veterans...

BACKGROUND: Youth are vulnerable to opioid use initiation and its complications. With growing rates of opioid overdose, strategies to identify youth at risk of opioid use disorder (OUD) to efficiently focus prevention interventions are needed. This study developed and validated a prediction model of OUD in youth aged 14-18 years. METHODS: The model was developed in a Colorado healthcare system (derivation site) using Cox proportional hazards regression analysis...

Jakub Frostig (1896-1959) was one of the most active Polish psychiatrists of the interwar period, with broad scientific interests, maintaining close scientific contacts with the leading specialists of world psychiatry, from the German -and English-language areas. This aspect of his activity is presented in the two-part publication based on new sources, which have never been used before, especially on the correspondence with Ludwig Binswanger (1881-1966), Max Müller (1894-1980) and Adolf Meyer (1866-1955), spanning several years...

Drug overdose is the leading cause of death among formerly incarcerated people. Distribution of the opioid overdose medication naloxone to people who use drugs reduces overdose mortality, and officials in many jurisdictions are now considering or implementing programs to offer naloxone to people exiting jails and prisons. The principles and practices of harm reduction programs such as naloxone distribution conflict with those of penal institutions, raising the question of how organizations based on opposing institutional logics can collaborate on lifesaving programs...

PURPOSE: Little is known about prevalence and treatment of OUD among youth engaged in primary care (PC). Medications are the recommended treatment of opioid use disorder (OUD) for adolescents and young adults (youth). This study describes the prevalence of OUD, the prevalence of medication treatment for OUD, and patient characteristics associated with OUD treatment among youth engaged in PC. METHODS: This cross-sectional study includes youth aged 16-25 years engaged in PC...

BACKGROUND AND AIMS: To estimate during pregnancy correlations between frequency of self-reported use of marijuana, and quantified marijuana metabolite in biospecimens including urine, sera, and umbilical cord homogenate. DESIGN: Prospective cohort SETTING: Two urban hospitals in Colorado with legal recreational and medicinal marijuana PARTICIPANTS: Pregnant women (<16 weeks' gestation) self-reporting marijuana use MEASUREMENTS: Participants completed a written self-report survey and provided biospecimens at <16 weeks' gestation (n=46), 18-22 weeks' gestation (n=43), 32-36 weeks' gestation (n=39) and delivery (n=37)...

OBJECTIVE: High rates of unintended pregnancy occur among women with opioid use disorder (OUD). OUD treatment settings may provide an ideal opportunity to address the family planning needs of patients. However, few studies have rigorously evaluated interventions designed to address family planning needs in the OUD treatment setting. This study assessed the feasibility, acceptability, and preliminary efficacy of a peer-led navigation intervention designed to educate and link women receiving medications for OUD to family planning services...