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Walid Blaiech, Mouna Ben Othmen, Ines Ouahchi, Meriam Alaya, Oussama Belkacem, Wissem Hmida, Mehdi Jaidane
INTRODUCTION AND IMPORTANCE: Paratesticular liposarcoma (PTL) is a rare condition, with fewer than 200 cases reported worldwide. It is a malignant tumor that originates from fat tissue with high risk of recurrence. Herein, the authors present a contralateral recurrence of a treated PTL. To the best of the authors' knowledge, in the current literature, there are few cases reported with recurrent PTL. CASE PRESENTATION: The authors report the case of a 62-year-old man who presented with a rapidly growing painless right hemiscrotal swelling...
May 2024: Annals of Medicine and Surgery
#2
Xiu-Qin Luo, Wan-Lin Qi, Qian Liu, Qing-Yun Zeng, Zhe-Huang Luo
INTRODUCTION: Angiomatoid fibrous histiocytoma (AFH) is a borderline tumor usually affecting the the children or young adults. 18F-Fluorodexoyglucose (FDG) positron emission tomography/computed tomography (PET/CT) investigations of pulmonary AFH are rare, and there are currently no reports of intense FDG uptake in AFH. CASE REPORT: We report an AFH that occurred in the lung of a 57-year-old woman. She presented with paroxysmal cough and occasional bloodshot sputum...
April 30, 2024: Current medical imaging
#3
JOURNAL ARTICLE
Patrick Silveira, Aria Razmaria, Randy Yeh
A 62-year-old man with de novo large volume metastatic prostate cancer to the bone, liver, and nodes status post multiple lines of therapy including external beam radiation to T12-L2 approximately 13 months prior underwent 68Ga-PSMA PET/CT to determine eligibility for 177Lu-PSMA therapy. 68Ga-PSMA PET/CT demonstrated tracer-avid osseous and nodal lesions consistent with metastases. In addition, regional geographic tracer avidity was seen in the midline left hepatic lobe associated with capsular retraction and demonstrated no FDG avidity on subsequent imaging, probably inflammatory related to prior radiation to T12-L2...
May 2, 2024: Clinical Nuclear Medicine
#4
EDITORIAL
David Groheux, Sofia C Vaz, Gary A Ulaner, Gary J R Cook, John Patrick Pilkington Woll, Ritse M Mann, Philip Poortmans, Fatima Cardoso, Heather Jacene, Stephanie L Graff, Isabel T Rubio, Marie-Jeanne Vrancken Peeters, Elizabeth H Dibble, Lioe-Fee de Geus-Oei
No abstract text is available yet for this article.
May 2, 2024: European Journal of Nuclear Medicine and Molecular Imaging
#5
Shagun, Alex Kim, Victoria Koshevarova, Payam Mohammadinejad, Micah Murphy, Peeyush Bhargava
This case report follows a 66-year-old female who originally presented with malignant melanoma in the left knee and recurrence in the left inguinal region. This prompted a whole body FDG PET/CT scan which showed incidental focal hypermetabolism in the uterus. The diagnosis of endometrial cancer was confirmed at biopsy, and the patient was treated with total abdominal hysterectomy. Melanoma patients are at increased risk of second primary malignancy, and endometrial cancer is a common second primary often diagnosed in cancer survivors...
July 2024: Radiology Case Reports
#6
JOURNAL ARTICLE
Ru Wang, Haidong Cai, Changcun Liu, Zhongwei Lv, Chao Ma
The concurrence of Hodgkin lymphoma and papillary thyroid carcinoma is a rare clinical event. Two women presented with a painless mass in the neck that was suspected malignancy by ultrasonography. Both cases shown in the 18F-FDG PET/CT images demonstrated multiple foci of increased FDG uptake in the neck, mimicking thyroid carcinoma with contralateral cervical lymph node metastases. Unexpectedly, the postoperative pathologies confirmed the thyroid lesion of papillary carcinoma and contralateral cervical lymph nodes of classical Hodgkin lymphoma...
May 1, 2024: Clinical Nuclear Medicine
#7
JOURNAL ARTICLE
Aurélie Moreau, Charlotte Chaouat, Thomas Walter, Aurélien Dupré, David Kryza
We report the case of a 25-year-old man who was undergoing follow-up for neurofibromatosis type 1. The man underwent 68Ga-DOTATOC PET/CT for a suspected well-differentiated duodenal neuroendocrine tumor. This examination did not reveal any significant uptake, whereas complementary 18F-FDG PET/CT showed moderate 18F-FDG uptake in the primary tumor as well as the adenopathy. Histology, a well-differentiated duodenal neuroendocrine tumor was confirmed, consistent with the diagnosis of somatostatinoma. Although rare, this well-differentiated neuroendocrine tumor should be kept in mind as a possible source of false-negative somatostatin receptor PET/CT findings...
May 1, 2024: Clinical Nuclear Medicine
#8
JOURNAL ARTICLE
Xuhe Liao, Hongwei Sun, Xueqi Chen, Yan Fan, Jianhua Zhang
Dedifferentiated liposarcoma is an extremely rare and highly malignant tumor. We demonstrated a case of a 75-year-old man with significantly PSMA-avid and mildly FDG uptake-dedifferentiated liposarcoma in the retroperitoneal area. The double-tracer (PSMA and FDG) PET scans could further contribute to differential diagnosis and the following treatment strategy for patients who were suspected with prostate cancer metastases and other malignant tumors simultaneously.
May 1, 2024: Clinical Nuclear Medicine
#9
REVIEW
Diana Paez, Francesco Giammarile, Anita Brink, Osvaldo García-Pérez, Enrique Estrada-Lobato
Spondylodiscitis, characterized by inflammation of the intervertebral disc and adjacent vertebral bodies, presents a diagnostic challenge due to its nonspecific clinical manifestations and variable imaging findings. This review examines the role of PET-CT with FDG, in the evaluation of spondylodiscitis, focusing on its utility in diagnosis, assessment of disease extent, treatment response monitoring, and prognostication. FDG PET-CT, by combining metabolic and anatomical imaging modalities, offers superior sensitivity and specificity compared to conventional imaging techniques in detecting infectious foci, distinguishing between infection and post-treatment changes, and identifying occult sources of infection...
April 29, 2024: Seminars in Nuclear Medicine
#10
REVIEW
Kip E Guja, Gerald Behr, Akshay Bedmutha, Marlena Kuhn, Helen R Nadel, Neeta Pandit-Taskar
Molecular imaging has emerged as an integral part of oncologic imaging. Given the physiologic changes that precede anatomic changes, molecular imaging can enable early detection of disease and monitoring of response. [18F] Fluorodeoxyglucose (FDG) Positron emission tomography (PET) is the predominant molecular imaging modality used in oncologic assessment and can be performed using PET/CT or PET/MR. In pediatric patients, PET/MRI imaging is generally preferred due to low radiation exposure and PET/MRI is particularly advantageous for imaging musculoskeletal (MSK) diseases, as MRI provides superior characterization of tissue changes as compared to CT...
April 29, 2024: Seminars in Nuclear Medicine
#11
JOURNAL ARTICLE
Yu Yu, Jing Zhu, Shibiao Sang, Yi Yang, Bin Zhang, Shengming Deng
OBJECTIVE: It is crucially essential to differentially diagnose single-nodule pulmonary metastases (SNPMs) and second primary lung cancer (SPLC) in patients with colorectal cancer (CRC), which has important clinical implications for treatment strategies. In this study, we aimed to establish a feasible differential diagnosis model by combining 18F-fluorodeoxyglucose positron-emission tomography (18F-FDG PET) radiomics, computed tomography (CT) radiomics, and clinical features. MATERIALS AND METHODS: CRC patients with SNPM or SPLC who underwent 18F-FDG PET/CT from January 2013 to July 2022 were enrolled in this retrospective study...
April 1, 2024: Journal of Cancer Research and Therapeutics
#12
JOURNAL ARTICLE
Yash Jain, Archi Agrawal, Amit Joshi, Santosh Menon, Gagan Prakash, Vedang Murthy, Nilendu Purandare, Sneha Shah, Ameya Puranik, Sayak Choudhury, Varun Shukla, Indraja Dev, Kumar Prabhash, Vanita Noronha, Venkatesh Rangarajan
AIM: To evaluate relationship between metabolic PET metabolic parameters and size of the primary tumor, various histopathological subtypes of renal cell carcinoma (RCC) and Fuhrman grade of the tumors. MATERIAL AND METHODS: Retrospective analysis of 93 biopsy-proven RCC patients who underwent pretreatment flourine 18 flourodeoxyglucose PET/computed tomography (18F FDG PET/CT) was performed. Quantitative PET parameters, size of the primary tumor, histopathological subtypes and Fuhrman grades of the tumor were extracted...
April 30, 2024: Nuclear Medicine Communications
#13
JOURNAL ARTICLE
Bin Wang, Xinming Zhao, Yunuan Liu, Zhaoqi Zhang, Xiaoshan Chen, Fenglian Jing, Xiaolin Chen, Yu Hua, Jianqiang Zhao
OBJECTIVE: The objective of this study is to evaluate the effectiveness of 68Ga-FAPI-04 PET/computed tomography (CT) for the diagnosis of primary and metastatic gastric cancer and colorectal cancer lesions as compared with 18F-FDG PET/CT. MATERIALS AND METHODS: Fifty-nine patients who underwent both 18F-FDG and 68Ga-FAPI-04 for initial staging or restaging were enrolled. Histopathological findings and clinical imaging follow-up were used as the reference standard...
April 29, 2024: Nuclear Medicine Communications
#14
Airi Miyazaki, Keishi Makino, Naoki Shinojima, Shinji Yamashita, Yoshiki Mikami, Akitake Mukasa
Pineal parenchymal tumors (PPTs) are rare, accounting for less than 0.3% of all primary central nervous system (CNS) tumors. Pineal parenchymal tumors of intermediate differentiation (PPTID) (WHO grade 2 or 3) show an intermediate prognosis between pineocytoma and pineoblastoma. The clinical course is unknown, and the optimal treatment for PPTID, especially for recurrence, has not been determined. We report a case of PPTID with spinal dissemination over 10 years after treatment and survival for four years. A 56-year-old woman presented with headaches and diplopia...
March 2024: Curēus
#15
REVIEW
Yaniv Yechiel, Alexandre Chicheportiche, Zohar Keidar, Simona Ben-Haim
Prostate cancer is the most common malignancy in men worldwide, with an estimated 174,650 new cases per year in the United States, and the second cancer-related cause of death, after lung cancer, with 31,620 deaths per year. While the 5 year survival rate for prostate cancer in patients without metastatic spread is nearly 100%, those with distant metastases have 5 year survival rates of approximately 30%. Initial diagnosis and assessment are based on PSA levels, Gleason score (derived from prostate biopsy), and advanced imaging modalities, including prostate MR imaging and PSMA-PET/computed tomography in patients with high-risk features...
April 27, 2024: PET Clinics
#16
JOURNAL ARTICLE
Barbara Hasse, Bruno Ledergerber, Mathias Van Hemelrijck, Michelle Frank, Martin W Huellner, Urs J Muehlematter, Ronny R Buechel, Lars Husmann
BACKGROUND: To identify FDG uptake patterns in PET/CT caused by infection, inflammation, surgical material and/or graft coating. METHODS AND RESULTS: Of 610 consecutive patients with thoracic aortic graft surgery, 60 patients with 187 PET/CT were retrospectively included. We quantified FDG uptake in all grafts, using maximum standardized uptake value (SUVmax) alone and in relation to liver background (SUVratio), and determined the uptake pattern. Mixed linear regression models with random slope and intercept were applied for the analysis of SUVratio over time and generalized estimating equations to analyze the associations with anastomosis uptake...
April 26, 2024: Journal of Nuclear Cardiology
#17
JOURNAL ARTICLE
Tiuri E Kroese, Sebastiaan Bronzwaer, Peter S N van Rossum, Sebastian F Schoppman, Pieter R A J Deseyne, Eric van Cutsem, Karin Haustermans, Philippe Nafteux, Melissa Thomas, Radka Obermannova, Hanna R Mortensen, Marianne Nordsmark, Per Pfeiffer, Anneli Elme, Antoine Adenis, Guillaume Piessen, Christiane J Bruns, Florian Lordick, Ines Gockel, Markus Moehler, Cihan Gani, Theodore Liakakos, John V Reynolds, Alessio G Morganti, Riccardo Rosati, Carlo Castoro, Francesco Cellini, Domenico D'Ugo, Franco Roviello, Maria Bencivenga, Giovanni de Manzoni, Mark I van Berge Henegouwen, Maarten C C M Hulshoff, Jolanda van Dieren, Marieke Vollebergh, Johanna W van Sandick, Paul Jeene, Christel Muijs, Marije Slingerland, Francine E M Voncken, Henk Hartgrink, Geert-Jan Creemers, Maurice J C van der Sangen, Grard A P Nieuwenhuijzen, Maaike Berbee, Marcel Verheij, Bas Wijnhoven, Laurens V Beerepoot, Nadia Haj Mohammad, Stella Mook, Jelle P Ruurda, Piotr Kolodziejczyk, Wojciech P Polkowski, Lucjan Wyrwicz, Maria Alsina, Josep Tabernero, Manuel Pera, Tania F Kanonnikoff, Andrés Cervantes, Magnus Nilsson, Stefan Monig, Anna D Wagner, Matthias Guckenberger, Ewen A Griffiths, Elizabeth Smyth, George B Hanna, Sheraz Markar, M Asif Chaudry, Maria A Hawkins, Edward Cheong, Hanneke W M van Laarhoven, Richard van Hillegersberg
INTRODUCTION: The OligoMetastatic Esophagogastric Cancer (OMEC) project aims to provide clinical practice guidelines for the definition, diagnosis, and treatment of esophagogastric oligometastatic disease (OMD). METHODS: Guidelines were developed according to AGREE II and GRADE principles. Guidelines were based on a systematic review (OMEC-1), clinical case discussions (OMEC-2), and a Delphi consensus study (OMEC-3) by 49 European expert centers for esophagogastric cancer...
April 16, 2024: European Journal of Cancer
#18
JOURNAL ARTICLE
Feng Liang, Guanxi Li, Junhong Guo, Wei Zhang, Xueli Chang
OBJECTIVE: Recent studies have utilized fluorine-18-fluorodeoxyglucose (18 F-FDG) positron emission tomography/computed tomography (PET/CT) specifically to diagnose cases of idiopathic inflammatory myopathies (IIM), excluding inclusion body myositis (IBM). Conversely, carbon-11 (11 C) labeled Pittsburgh compound B (PIB)-PET imaging is exclusively used for the detection of IBM. This research is designed to evaluate the diagnostic accuracy of PET/CT in identifying IIM by employing rigorous diagnostic accuracy testing methodologies...
2024: Hellenic Journal of Nuclear Medicine
#19
JOURNAL ARTICLE
Yukinori Okada, Tatsuhiko Zama, Tomohiro Itonaga, Ryuji Mikami, Mitsuru Okubo, Shinji Sugahara, Masahiko Kurooka, Motoki Nakai, Koichiro Abe, Mana Yoshimura, Kazuhiro Saito
OBJECTIVE: To investigate the positron emission tomography/computed tomography (PET/CT) findings of T1/T2N0M0 glottic cancer (hereafter referred to as T1/T2) and dose distribution in radiotherapy. SUBJECTS AND METHODS: We retrospectively collected data from patients diagnosed with T1/T2N0M0 glottic cancer who received radiotherapy. The extent of fluorine-18-fluorodeoxyglucose (18 F-FDG) accumulation in primary tumors, maximum standardized uptake value (SUVmax), total lesion glycolysis (TLG), tumor volume of primary tumors on PET/CT were compared...
2024: Hellenic Journal of Nuclear Medicine
#20
JOURNAL ARTICLE
Hikari Ota, Satoshi Nakayama, Hiroaki Takeo, Sadahiro Watanabe, Kazuhiro Masuoka
BACKGROUND Intravascular large B-cell lymphoma (IVLBCL) is a rare extranodal large B-cell lymphoma characterized by the selective growth of lymphoma cells within vasculature. This presents a diagnostic challenge due to non-specific symptoms and lack of tumor formation. 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) provides useful information in diagnosing FDG-avid lymphoma, but is not specific to IVLBCL. Contrast-enhanced ultrasonography (CEUS) is useful in evaluating focal liver lesions; however, its efficacy in diagnosing IVLBCL involving the liver remains unknown...
April 28, 2024: American Journal of Case Reports
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