keyword
https://read.qxmd.com/read/38166623/genomic-evaluation-for-breeding-and-genetic-management-in-cordia-africana-a-multipurpose-tropical-tree-species
#41
JOURNAL ARTICLE
Kedra M Ousmael, Eduardo P Cappa, Jon K Hansen, Prasad Hendre, Ole K Hansen
BACKGROUND: Planting tested forest reproductive material is crucial to ensure the increased resilience of intensively managed productive stands for timber and wood product markets under climate change scenarios. Single-step Genomic Best Linear Unbiased Prediction (ssGBLUP) analysis is a cost-effective option for using genomic tools to enhance the accuracy of predicted breeding values and genetic parameter estimation in forest tree species. Here, we tested the efficiency of ssGBLUP in a tropical multipurpose tree species, Cordia africana, by partial population genotyping...
January 2, 2024: BMC Genomics
https://read.qxmd.com/read/38166525/genome-wide-association-study-of-agronomic-traits-related-to-nitrogen-use-efficiency-in-henan-wheat
#42
JOURNAL ARTICLE
Zaicheng Zhang, Chaojun Peng, Weigang Xu, Yan Li, Xueli Qi, Mingzhong Zhao
BACKGROUND: Nitrogen use efficiency (NUE) is closely related to crop yield and nitrogen fertilizer application rate. Although NUE is susceptible to environments, quantitative trait nucleotides (QTNs) for NUE in wheat germplasm populations have been rarely reported in genome-wide associated study. RESULTS: In this study, 244 wheat accessions were phenotyped by three NUE-related traits in three environments and genotyped by 203,224 SNPs. All the phenotypes for each trait were used to associate with all the genotypes of these SNP markers for identifying QTNs and QTN-by-environment interactions via 3VmrMLM...
January 2, 2024: BMC Genomics
https://read.qxmd.com/read/38149679/identification-of-ago2-and-plec-genes-polymorphisms-in-hu-sheep-and-their-relationship-with-body-size-traits
#43
JOURNAL ARTICLE
Jia Liu, Wenxin Zheng, Weimin Wang, Xiaobin Yang, Yongliang Huang, Panpan Cui, Zongwu Ma, Xiwen Zeng, Rui Zhai, Xiuxiu Weng, Weiwei Wu, Xiaoxue Zhang
The body size traits are major traits in livestock, which intuitively displays the development of the animal's bones and muscles. This study used PCR amplification, Sanger sequencing, KASPar genotyping, and quantitative real-time reverse transcription PCR (qRT-PCR) to analyze the Single-nucleotide polymorphism and expression characteristics of Argonaute RISC catalytic component 2 ( AGO2 ) and Plectin ( PLEC ) genes in Hu sheep. Two intron mutations were found in Hu sheep, which were AGO2 g.51700 A > C and PLEC g...
December 27, 2023: Animal Biotechnology
https://read.qxmd.com/read/38142253/identification-of-a-novel-snp-in-the-mir172-binding-site-of-q-homoeolog-ap2l-d5-is-associated-with-spike-compactness-and-agronomic-traits-in-wheat-triticum-aestivum-l
#44
JOURNAL ARTICLE
Victoria Zeng, Cristobal Uauy, Yi Chen
This study found that the compact spike locus of ANK-15 is on chromosome 5D instead of 2B. We have identified a new allele of AP2L-D5 as the candidate causal polymorphism. Spike architecture is a key determinant of wheat yield, a crop which supports much of the human diet but whose yield gains are stagnating. Spike architecture mutants offer opportunities to identify genetic factors contributing to inflorescence development. Here, we investigate the locus underlying the compact spike phenotype of mutant line ANK-15 by conducting mRNA-sequencing and genetic mapping using ANK-15 and its non-compact spike near-isogenic line Novosibirskaya 67 (N67)...
December 23, 2023: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://read.qxmd.com/read/38136962/functional-characterization-of-the-almstn2-gene-and-its-association-with-growth-traits-in-the-yellowfin-seabream-acanthopagrus-latus-hottuyn-1782
#45
JOURNAL ARTICLE
Jianyi Guo, Huayang Guo, Chuanghua Chen, Fangzhao Yu, Baosuo Liu, Nan Zhang, Lin Xian, Zhiping Luo, Wen Liu, Kecheng Zhu, Dianchang Zhang
Myostatin (mstn), also known as GDF8, is a growth and differentiation factor of the transforming growth factor-β (TGF-β) superfamily and plays a key inhibitory effect in the regulation of skeletal muscle development and growth in vertebrates. In the present study, to comprehend the role of the mstn2 gene of the yellowfin seabream Acanthopagrus latus ( Almstn2b ), the genomic sequence of Almstn2b is 2359 bp, which encodes 360 amino acids and is composed of three exons and two introns, was obtained...
November 27, 2023: Genes
https://read.qxmd.com/read/38135043/genome-wide-association-study-of-age-at-puberty-and-its-co-variances-with-fertility-and-stature-in-growing-and-lactating-holstein-friesian-dairy-cattle
#46
JOURNAL ARTICLE
M A Stephen, C R Burke, N Steele, J E Pryce, S Meier, P R Amer, C V C Phyn, D J Garrick
Reproductive performance is a key determinant of cow longevity in a pasture-based, seasonal dairy system. Unfortunately, direct fertility phenotypes such as inter-calving interval or pregnancy rate tend to have low heritabilities and occur relatively late in an animal's life. In contrast, age at puberty (AGEP) is a moderately heritable, early-in-life trait, that may be estimated using an animal's age at first measured elevation in blood plasma progesterone (AGEP4) concentrations. Understanding the genetic architecture of AGEP4 in addition to genetic relationships between AGEP4 and fertility traits in lactating cows is important, as is its relationship with body size in the growing animal...
December 20, 2023: Journal of Dairy Science
https://read.qxmd.com/read/38111387/inheritance-of-body-size-and-ultrasound-carcass-traits-in-yearling-anatolian-buffalo-calves
#47
JOURNAL ARTICLE
Samet Çinkaya, Mustafa Tekerli
The body size and ultrasound carcass traits are related to the growth and muscling of animals. These characters promise future improvement through genetic selection in animal breeding. In breeding programs, knowing the (co)variance components serves to reveal the performance differences among animals and detection of suitable traits for selection. The research was carried out with 313 Anatolian buffalo calves born in 2019 at 36 farm operations. The least-square means for body weight (BW), wither height (WH), rump height (RH), body length (BL), chest width (CW), hip width (HW), chest circumference (CC), cannon-bone circumference (CBC), longissimus muscle area (LMA), longissimus muscle depth (LMD), and subcutaneous fat thickness (SFT) in yearling calves were 175...
2023: Archives animal breeding
https://read.qxmd.com/read/38110866/ridge-regression-and-deep-learning-models-for-genome-wide-selection-of-complex-traits-in-new-mexican-chile-peppers
#48
JOURNAL ARTICLE
Dennis N Lozada, Karansher Singh Sandhu, Madhav Bhatta
BACKGROUND: Genomewide prediction estimates the genomic breeding values of selection candidates which can be utilized for population improvement and cultivar development. Ridge regression and deep learning-based selection models were implemented for yield and agronomic traits of 204 chile pepper genotypes evaluated in multi-environment trials in New Mexico, USA. RESULTS: Accuracy of prediction differed across different models under ten-fold cross-validations, where high prediction accuracy was observed for highly heritable traits such as plant height and plant width...
December 18, 2023: BMC genomic data
https://read.qxmd.com/read/38110604/the-polymorphism-of-the-ovine-insulin-like-growth-factor-2-igf2-gene-and-their-associations-with-growth-related-traits-in-tibetan-sheep
#49
JOURNAL ARTICLE
Xianlin Zhao, Jinyun Yan, Hanping Chu, Zhenling Wu, Wendi Li, Qing Zhang, Yu Zhang, Yanmin Guo, Zhaobin Fan
In the current study, the role of the ovine IGF2 as a potential candidate gene was investigated as though marker-assisted selection in Chinese Tibetan sheep. The Sanger DNA sequencing method explored five single nucleotide polymorphisms (SNPs) in 5'UTR of the ovine IGF2 gene (C15640T, G15801A, G15870A, C15982G and G15991A) in Chinese Tibetan sheep. The frequencies of four SNPs were within the Hardy-Weinberg Equilibrium (chi-square test) except C15982G. The statistical analysis indicated that the C15640T and G15801A were significantly associated with body height, body length, chest circumference, and body weight (P < 0...
December 18, 2023: Tropical Animal Health and Production
https://read.qxmd.com/read/38081914/pilot-scale-genome-wide-association-mapping-in-diverse-sorghum-germplasms-identified-novel-genetic-loci-linked-to-major-agronomic-root-and-stomatal-traits
#50
JOURNAL ARTICLE
Ajay Prasanth Ramalingam, Williams Mohanavel, Rohit Kambale, Veera Ranjani Rajagopalan, Sandeep R Marla, P V Vara Prasad, Raveendran Muthurajan, Ramasamy Perumal
This genome-wide association studies (GWAS) used a subset of 96 diverse sorghum accessions, constructed from a large collection of 219 accessions for mining novel genetic loci linked to major agronomic, root morphological and physiological traits. The subset yielded 43,452 high quality single nucleotide polymorphic (SNP) markers exhibiting high allelic diversity. Population stratification showed distinct separation between caudatum and durra races. Linkage disequilibrium (LD) decay was rapidly declining with increasing physical distance across all chromosomes...
December 8, 2023: Scientific Reports
https://read.qxmd.com/read/38075675/unveiling-the-common-loci-for-six-body-measurement-traits-in-chinese-wenshan-cattle
#51
JOURNAL ARTICLE
Honghui Ren, Xiaoming He, Ying Lu, Dan Yue, Xingneng Liu, Dongwang Wu, Junhong Zhu, Zhendong Gao, Dongmei Xi, Weidong Deng
Introduction: Body measurement traits are integral in cattle production, serving as pivotal criteria for breeding selection. Wenshan cattle, a local breed in China's Yunnan province, exhibit remarkable genetic diversity. However, the molecular mechanisms regulating body measurement traits in Wenshan cattle remain unexplored. Methods: In this study, we performed a genome-wide association method to identify genetic architecture for body height body length hip height back height (BAH), waist height and ischial tuberosity height using the Bovine 50 K single nucleotide polymorphism Array in 1060 Wenshan cattles...
2023: Frontiers in Genetics
https://read.qxmd.com/read/38066979/genome-wide-association-study-reveals-novel-loci-associated-with-body-conformation-traits-in-qinchuan-cattle
#52
JOURNAL ARTICLE
Hengwei Yu, Shengchen Yu, Juntao Guo, Gong Cheng, Chugang Mei, Linsen Zan
A genome-wide association study (GWAS) is an effective tool for identifying the dominant genes of complex economic traits in livestock by statistical analysis of genotype data and measured phenotype data. In this study, we rigorously measured 14 body conformation traits in 254 Qinchuan cattle, comprising body weight (BW), body height (BOH), back height (BAH), buttock height (BUH), chest depth (CD), chest width (CW), hip cross height (HCH), body length (BL), hip width (HW), rump length (RL), pin bone width (PBW), chest girth (CG), abdomen circumference (AG), and calf circumference (CC)...
November 23, 2023: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38065030/systematic-evaluation-of-the-precision-id-globalfiler%C3%A2-ngs-str-panel-v2-using-single-source-samples-of-various-quantity-and-quality-and-mixed-dna-samples
#53
JOURNAL ARTICLE
Vishakha Sharma, Elisa Wurmbach
Massively parallel sequencing (MPS) techniques were developed approximately 15 years ago. Meanwhile, several MPS kits for forensic identification, phenotypic information, ancestry, and mitochondrial DNA analysis have been developed and their use has been established. Sequencing short tandem repeats (STRs) has certain advantages over the currently used length-based genotyping methods, which are based on PCR amplification followed by capillary electrophoresis (CE). MPS is more discriminative and includes the possibility of testing high numbers of targets (> 100), different types of markers [STRs and single nucleotide polymorphisms (SNPs)], as well as the use of smaller amplicons (< 300 bp)...
December 2, 2023: Forensic Science International. Genetics
https://read.qxmd.com/read/38024957/high-resolution-genetic-linkage-map-and-height-related-qtls-in-an-oil-palm-elaeis-guineensis-family-planted-across-multiple-sites
#54
JOURNAL ARTICLE
Ngoot-Chin Ting, Pek-Lan Chan, Jaap Buntjer, Jared M Ordway, Corey Wischmeyer, Leslie Cheng-Li Ooi, Eng Ti Leslie Low, Marhalil Marjuni, Ravigadevi Sambanthamurthi, Rajinder Singh
UNLABELLED: A refined SNP array containing 92,459 probes was developed and applied for chromosome scanning, construction of a high-density genetic linkage map and QTL analysis in a selfed Nigerian oil palm family (T128). Genotyping of the T128 mapping family generated 76,447 good quality SNPs for detailed scanning of aberration and homozygosity in the individual pseudo-chromosomes. Of them, 25,364 polymorphic SNPs were used for linkage analysis resulting in an 84.4% mapping rate. A total of 21,413 SNPs were mapped into 16 linkage groups (LGs), covering a total map length of 1364...
September 2023: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
https://read.qxmd.com/read/38023878/comparing-modeling-methods-of-genomic-prediction-for-growth-traits-of-a-tropical-timber-species-shorea-macrophylla
#55
JOURNAL ARTICLE
Haruto Akutsu, Mohammad Na'iem, Widiyatno, Sapto Indrioko, Sawitri, Susilo Purnomo, Kentaro Uchiyama, Yoshihiko Tsumura, Naoki Tani
INTRODUCTION: Shorea macrophylla is a commercially important tropical tree species grown for timber and oil. It is amenable to plantation forestry due to its fast initial growth. Genomic selection (GS) has been used in tree breeding studies to shorten long breeding cycles but has not previously been applied to S. macrophylla . METHODS: To build genomic prediction models for GS, leaves and growth trait data were collected from a half-sib progeny population of S. macrophylla in Sari Bumi Kusuma forest concession, central Kalimantan, Indonesia...
2023: Frontiers in Plant Science
https://read.qxmd.com/read/38003024/development-of-high-yielding-upland-cotton-genotypes-with-reduced-regrowth-after-defoliation-using-a-combination-of-molecular-and-conventional-approaches
#56
JOURNAL ARTICLE
Salman Naveed, Johnson Toyinbo, Hrishikesh Ingole, Prasanna Valavanur Shekar, Michael Jones, B Todd Campbell, Sachin Rustgi
Cotton is an economically important crop. However, the yield gain in cotton has stagnated over the years, probably due to its narrow genetic base. The introgression of beneficial variations through conventional and molecular approaches has helped broaden its genetic base to some extent. The growth habit of cotton is one of the crucial factors that determine crop maturation time, yield, and management. This study used 44 diverse upland cotton genotypes to develop high-yielding cotton germplasm with reduced regrowth after defoliation and early maturity by altering its growth habit from perennial to somewhat annual...
November 15, 2023: Genes
https://read.qxmd.com/read/37989964/rht12b-a-widely-used-ancient-allele-of-taga2oxa13-reduces-plant-height-and-enhances-yield-potential-in-wheat
#57
JOURNAL ARTICLE
Yingjie Bian, Lingli Li, Xiuling Tian, Dengan Xu, Mengjing Sun, Faji Li, Lina Xie, Siyang Liu, Bingyan Liu, Xianchun Xia, Zhonghu He, Shuanghe Cao
We identified a new wheat dwarfing allele Rht12b conferring reduced height and higher grain yield, pinpointed its causal variations, developed a breeding-applicable marker, and traced its origin and worldwide distribution. Plant height control is essential to optimize lodging resistance and yield gain in crops. RHT12 is a reduced height (Rht) locus that is identified in a mutationally induced dwarfing mutant and encodes a gibberellin 2-oxidase TaGA2oxA13. However, the artificial dwarfing allele is not used in wheat breeding due to excessive height reduction...
November 21, 2023: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://read.qxmd.com/read/37927339/shared-genetic-architecture-of-covid-19-and-alzheimer-s-disease
#58
REVIEW
Natalia Matveeva, Ivan Kiselev, Natalia Baulina, Ekaterina Semina, Viktor Kakotkin, Mikhail Agapov, Olga Kulakova, Olga Favorova
The severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) and the сoronavirus disease 2019 (COVID-19) have become a global health threat. At the height of the pandemic, major efforts were focused on reducing COVID-19-associated morbidity and mortality. Now is the time to study the long-term effects of the pandemic, particularly cognitive impairment associated with long COVID. In recent years much attention has been paid to the possible relationship between COVID-19 and Alzheimer's disease, which is considered a main cause of age-related cognitive impairment...
2023: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/37905391/higher-atherogenic-risk-in-schoolchildren-is-associated-with-mtmr9-rs2293855-gene-polymorphism-and-genetic-score
#59
JOURNAL ARTICLE
Mariane Alves Silva, Cristina Maria Mendes Resende, Maíra Barros Louro, Sarah Aparecida Vieira Ribeiro, Sylvia do Carmo Castro Franceschini, Gustavo Velasquez-Melendez, Jacqueline Isaura Alvarez-Leite, Danielle Fernandes Durso, Juliana Farias de Novaes
Childhood dyslipidaemia is associated with the occurrence of cardiovascular diseases in adulthood, so evaluating whether an individual has a genetic predisposition to this pathology is of great importance for early action of prevention and treatment. This study aimed to evaluate the association between the FTO (rs9939609), MC4R (rs17782313) and MTMR9 (rs2293855) polymorphisms, the obesity-related genetic risk score and atherogenic risk in Brazilian children. This is a cross-sectional study conducted in 544 children aged 4-9 years in the city of Viçosa, Minas Gerais state, Brazil...
October 31, 2023: Nutrition Bulletin
https://read.qxmd.com/read/37893961/genome-wide-association-and-pathway-analysis-of-carcass-and-meat-quality-traits-in-karachai-young-goats
#60
JOURNAL ARTICLE
Marina Selionova, Magomet Aibazov, Alexander Sermyagin, Anna Belous, Tatiana Deniskova, Tatiana Mamontova, Ekaterina Zharkova, Natalia Zinovieva
Goats with diverse economic phenotypic traits play an important role in animal husbandry. However, the genetic mechanisms underlying complex phenotypic traits are unclear in goats. Genomic studies of variations provided a lens to identify functional genes. The work aimed to search for candidate genes related to body measurements and body weight of Karachai goats and develop an experimental PCR-RV test system for genotyping significant SNPs. Comparison of GWAS results for ages 4 and 8 months revealed 58 common SNPs for significant genotypes...
October 17, 2023: Animals: An Open Access Journal From MDPI
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