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JOURNAL ARTICLE
Dolores González de Llano, Mikel Roldán, Diego Taladrid, Edgard Relaño de la Guía, M Victoria Moreno-Arribas, Begoña Bartolomé
This work seeks to generate new knowledge about the mechanisms underlying the protective effects of cranberry against urinary tract infections (UTI). Using Caco-2 cells grown in Transwell inserts as an intestinal barrier model, we found that a cranberry-derived digestive fluid (containing 135 ± 5 mg of phenolic compounds/L) increased transepithelial electrical resistance with respect to control (ΔTEER = 54.5 Ω cm2 ) and decreased FITC-dextran paracellular transport by about 30%, which was related to the upregulation of the gene expression of tight junction (TJ) proteins (i...
April 23, 2024: Journal of Agricultural and Food Chemistry
#2
JOURNAL ARTICLE
Abel A Pavía-López, José A Magaña-Serrano, José A Cigarroa-López, Adolfo Chávez-Mendoza, José L Mayorga-Butrón, Diego Araiza-Garaygordobil, Juan B Ivey-Miranda, Gustavo F Méndez-Machado, Héctor González-Godínez, Luisa F Aguilera-Mora, Antonio Jordán-Ríos, Luis Olmos-Domínguez, Marcos J Olalde-Román, Emma M Miranda-Malpica, Zuilma Vázquez-Ortiz, Jorge Rayo-Chávez, Alexandra A Mendoza, Manlio F Márquez-Murillo, Sergio A Chávez-Leal, Amada Álvarez-San Gabriel, Marissa A Silva-García, Alex D Pacheco-Bouthiller, Jorge A Aldrete-Velazco, Carlos A Guizar-Sánchez, Efraín Gaxiola-López, Arturo Guerra-López, Lourdes Figueiras-Graillet, Gustavo Sánchez-Miranda, Genaro H Mendoza-Zavala, Moisés Aceves-García, Adolfo Chávez-Negrete, Marisol Arroyo-Hernández, Bertha B Montaño-Velázquez, Luis F Romero-Moreno, María M Baquero-Hoyos, Liliana Velasco-Hidalgo, Ana L Rodríguez-Lozano, Nancy E Aguilar-Gómez, Mario Rodríguez-Vega, Jorge E Cossío-Aranda
Chronic heart failure continues to be one of the main causes of impairment in the functioning and quality of life of people who suffer from it, as well as one of the main causes of mortality in our country and around the world. Mexico has a high prevalence of risk factors for developing heart failure, such as high blood pressure, diabetes, and obesity, which makes it essential to have an evidence-based document that provides recommendations to health professionals involved in the diagnosis and treatment of these patients...
2024: Archivos de Cardiología de México
#3
D López, F Espinel, E Andrade, A S Aguirre
In pediatric patients, an acute altered mental status refers to a sudden and significant change in a child's brain function and level of consciousness. It may manifest as confusion, disorientation, agitation, lethargy or even a loss of consciousness. This condition is a medical emergency, and requires immediate evaluation and attention. There are several causes of acute altered mental status in children, including infections of the central nervous system such as meningitis or encephalitis, traumatic brain injury, metabolic disorders, seizures and poisoning, among others...
April 16, 2024: Revista de Neurologia
#4
Guilherme Vilhais, Diogo Alpuim Costa, Mário Fontes-Sousa, Pedro Casal Ribeiro, Filipa Martinho, Carolina Botelho de Sousa, Catarina Rodrigues Santos, Ida Negreiros, Ana Canastra, Paula Borralho, Ana Guia Pereira, Cristina Marçal, José Germano Sousa, Renata Chaleira, Júlio César Rocha, Conceição Calhau, Ana Faria
Locally advanced breast cancer poses significant challenges to the multidisciplinary team, in particular with hormone receptor (HR) positive, HER2-negative tumors that classically yield lower pathological complete responses with chemotherapy. The increasingly significant use of CDK 4/6 inhibitors (CDK4/6i) plus endocrine therapy (ET) in different breast cancer settings has led to clinical trials focusing on this strategy as a primary treatment, with promising results. The impact of the microbiota on cancer, and vice-versa, is an emerging topic in oncology...
2024: Frontiers in Oncology
#5
Javier Delgado-Lista, Jose M Mostaza, Teresa Arrobas-Velilla, Francisco Blanco-Vaca, Luis Masana, Juan Pedro-Botet, Pablo Perez-Martinez, Fernando Civeira, Jose I Cuende-Melero, Jose J Gomez-Barrado, Carlos Lahoz, Xavier Pintó, Manuel Suarez-Tembra, Jose Lopez-Miranda, Carlos Guijarro
The irruption of lipoprotein(a) (Lp(a)) in the study of cardiovascular risk factors is perhaps, together with the discovery and use of proprotein convertase subtilisin/kexin type 9 (iPCSK9) inhibitor drugs, the greatest novelty in the field for decades. Lp(a) concentration (especially very high levels) has an undeniable association with certain cardiovascular complications, such as atherosclerotic vascular disease (AVD) and aortic stenosis. However, there are several current limitations to both establishing epidemiological associations and specific pharmacological treatment...
April 9, 2024: Clínica e Investigación en Arteriosclerosis
#6
JOURNAL ARTICLE
Eva Muñoz, Javier Cañueto Álvarez, Josep Oriol Bermejo Segú, Almudena García Castaño, Vanessa Gabriela Jerviz Guía, Ana María López López, Susana Puig Sardá, Onofre Sanmartín Jiménez, Ainara Soria Rivas, Paula Gratal, Teresa Pardo, Alvaro Rogado, Alfonso Berrocal
No abstract text is available yet for this article.
April 5, 2024: Journal of the National Comprehensive Cancer Network: JNCCN
#7
JOURNAL ARTICLE
Antonio Tello Montoliu, Agustín Olea González, Ángel Pujante Escudero, María Martínez Del Villar, Fernando de la Guía Galipienso, Leonel Díaz González, Rosa Fernández Olmo, Román Freixa-Pamias, David Vivas Balcones
The practice of recreational scuba diving has increased worldwide, with millions of people taking part each year. The aquatic environment is a hostile setting that requires human physiology to adapt by undergoing a series of changes that stress the body. Therefore, physical fitness and control of cardiovascular risk factors are essential for practicing this sport. Medical assessment is not mandatory before participating in this sport and is only required when recommended by a health questionnaire designed for this purpose...
April 3, 2024: Revista Española de Cardiología
#8
JOURNAL ARTICLE
Felipe Díez-Delhoyo, María T López Lluva, Pedro Cepas-Guillén, Alfonso Jurado-Román, Pablo Bazal-Chacón, Martín Negreira-Caamaño, Iván Olavarri-Miguel, Ane Elorriaga, Jose A Fernández-Sánchez, David Escribano, Pablo Salinas, Jessica Vaquero-Luna, Alicia Prieto-Lobato, Lucía Pérez-Cebey, Anna Carrasquer, Isaac Llaóo, Fernando J Torres Mezcúa, Teresa Giralt-Borrell, María Abellas, Sergio García-Blas, Lucía Matute-Blanco, Carolina Robles-Gamboa, Antonio Martínez-Guisado, Clara Fernández-Cordón, Clea González-Maniega, Pablo Díez-Villanueva
INTRODUCTION AND OBJECTIVES: The optimal timing of coronary angiography in patients admitted with non-ST-segment elevation acute coronary syndrome (NSTEACS) as well as the need for pretreatment are controversial. The main objective of the IMPACT-TIMING-GO registry was to assess the proportion of patients undergoing an early invasive strategy (0-24hours) without dual antiplatelet therapy (no pretreatment strategy) in Spain. METHODS: This observational, prospective, and multicenter study included consecutive patients with NSTEACS who underwent coronary angiography that identified a culprit lesion...
March 2024: Revista Española de Cardiología
#9
REVIEW
Fernando de la Guía-Galipienso, Patricia Palau, Alejandro Berenguel-Senen, Carme Perez-Quilis, Jeffrey W Christle, Jonathan Myers, François Haddad, Aaron Baggish, Flavio D'Ascenzi, Carl J Lavie, Giuseppe Lippi, Fabian Sanchis-Gomar
Endurance and resistance physical activity have been shown to stimulate the production of immunoglobulins and boost the levels of anti-inflammatory cytokines, natural killer cells, and neutrophils in the bloodstream, thereby strengthening the ability of the innate immune system to protect against diseases and infections. Coronavirus disease 19 (COVID-19) greatly impacted people's cardiorespiratory fitness (CRF) and health worldwide. Cardiopulmonary exercise testing (CPET) remains valuable in assessing physical condition, predicting illness severity, and guiding interventions and treatments...
March 5, 2024: Progress in Cardiovascular Diseases
#10
JOURNAL ARTICLE
Andréia Maria Silva Vilela Terra, Paulo Duarte Guia Santos, Miguel Gomes, Adriana Teresa Silva Santos, Pedro Pezarat-Correia
OBJECTIVE: This study aimed investigate the effect of auriculotherapy on exercise-induced muscle fatigue, isometric torque production, and surface electromyographic activity (EMG). METHODS: Design: Randomized Crossover Trial. The sample consisted of 18 males' volunteers who exercised at least twice a week. THE SAMPLE WAS RANDOMLY ASSIGNED TO TWO GROUPS: Placebo Group (n = 9) and Treated Group (n = 9), and after seven days, the groups were crossed...
January 2024: Journal of Bodywork and Movement Therapies
#11
JOURNAL ARTICLE
José María García-Alberca, Itziar de Rojas, Elisabeth Sanchez-Mejias, Diego Garrido-Martín, Laura Gonzalez-Palma, Sebastian Jimenez, Almudena Pino-Angeles, Jose Manuel Cruz-Gamero, Silvia Mendoza, Emilio Alarcón-Martín, Clara Muñoz-Castro, Luis Miguel Real, Juan Jesus Tena, Rocio Polvillo, Fernando Govantes, Aroa Lopez, Jose Luis Royo-Aguado, Victoria Navarro, Irene Gonzalez, Maximiliano Ruiz, Armando Reyes-Engel, Esther Gris, Maria Jose Bravo, Lidia Lopez-Gutierrez, Marina Mejias-Ortega, Paz De la Guía, María López de la Rica, Olga Ocejo, Javier Torrecilla, Carmen Zafra, María Dolores Nieto, Concepción Urbano, Rocío Jiménez-Sánchez, Nuria Pareja, Macarena Luque, María García-Peralta, Rosario Carrillejo, María Del Carmen Furniet, Lourdes Rueda, Ana Sánchez-Fernández, Tomás Mancilla, Isabel Peña, Natalia García-Casares, Sonia Moreno-Grau, Isabel Hernández, Laura Montrreal, Inés Quintela, Antonio González-Pérez, Miguel Calero, Emilio Franco-Macías, Juan Macías, Manuel Menéndez-González, Ana Frank-García, Raquel Huerto Vilas, Mónica Diez-Fairen, Carmen Lage, Sebastián García-Madrona, Pablo García-González, Sergi Valero, Oscar Sotolongo-Grau, Alba Pérez-Cordón, Alberto Rábano, Alfonso Arias Pastor, Ana Belén Pastor, Ana Espinosa, Anaïs Corma-Gómez, Ángel Martín Montes, Ángela Sanabria, Carmen Martínez Rodríguez, Dolores Buiza-Rueda, Eloy Rodriguez-Rodriguez, Gemma Ortega, Ignacio Alvarez, Irene Rosas Allende, Juan A Pineda, Maitée Rosende-Roca, María Bernal Sánchez-Arjona, Marta Fernández-Fuertes, Montserrat Alegret, Natalia Roberto, Teodoro Del Ser, Guillermo Garcia-Ribas, Pascual Sánchez-Juan, Pau Pastor, Gerard Piñol-Ripoll, María José Bullido, Victoria Álvarez, Pablo Mir, Miguel Medina, Marta Marquié, María Eugenia Sáez, Ángel Carracedo, Marina Laplana, Laura Tomas-Gallardo, Adelina Orellana, Lluís Tárraga, Mercè Boada, Joan Fibla Palazon, Javier Vitorica, Agustín Ruiz, Roderic Guigo, Antonia Gutierrez, Jose Luis Royo
BACKGROUND: Microglial dysfunction plays a causative role in Alzheimer's disease (AD) pathogenesis. Here we focus on a germline insertion/deletion variant mapping SIRPβ1, a surface receptor that triggers amyloid-β(Aβ) phagocytosis via TYROBP. OBJECTIVE: To analyze the impact of this copy-number variant in SIRPβ1 expression and how it affects AD molecular etiology. METHODS: Copy-number variant proxy rs2209313 was evaluated in GERALD and GR@ACE longitudinal series...
February 26, 2024: Journal of Alzheimer's Disease: JAD
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JOURNAL ARTICLE
Soraya Patricia Salas-Romero, Zorayda Barrios-Puerta, Kendy Paola Madero-Zambrano, Ana María Bello-Trujillo
OBJETIVOS: describir los conocimientos, la idoneidad y las prácticas respecto a la "Guía de práctica clínica (GPC) basada en la evidencia para la atención integral de la sífilis gestacional (SG) y congénita (SC)". Materiales y métodos: estudio descriptivo de corte transversal. Incluyó médicos generales, especialistas y enfermeras que laboraban en 52 instituciones de salud en el departamento de Bolívar (Colombia) y realizan el control prenatal o la atención al neonato en el 2020...
December 30, 2023: Revista Colombiana de Obstetricia y Ginecología
#13
JOURNAL ARTICLE
[Evaluación de la implementación de las Guías de Práctica Clínica. Una tarea pendiente en Colombia].
Hernando Gaitán-Duarte
No abstract text is available yet for this article.
December 30, 2023: Revista Colombiana de Obstetricia y Ginecología
#14
JOURNAL ARTICLE
Berta Rodoreda-Pallàs, Eva Torra Escarrer, Jaume Sanahuja Juncadella, Teresa Pampalona Cardona, Nuria Solanas Bacardit, Montserrat Vilarrubias Calaf
OBJECTIVE: To evaluate a coding guide for social determinants of health in primary care consultations as an effective tool in the professional's daily workflow. DESIGN: Mixed sequential explanatory study. Formed by a quantitative part (experimental) and a qualitative part (descriptive-evaluative). LOCATION: All the primary care teams of the Central Catalonia Management (32 teams). PARTICIPANTS AND SETTING: All nursing, social work and medical professionals working in the 32 primary care teams of the Catalan Institute of Health in Central Catalonia from February 2023 to July 2023...
February 23, 2024: Atencion Primaria
#15
M Sandoval-Garcés, A Wang, A Martin-Gorgojo
No abstract text is available yet for this article.
February 20, 2024: Actas Dermo-sifiliográficas
#16
EDITORIAL
Javier Bracchiglione, Pablo Alonso-Coello
No abstract text is available yet for this article.
February 19, 2024: Medicina Clínica
#17
JOURNAL ARTICLE
Arren Christian M de Guia, Mary Rose D Uy-de Guia, Juvy J Monserate, Joel R Salazar, Ravelina R Velasco, Claro N Mingala, Karl Marx A Quiazon
OBJECTIVE: The aerolysin (aerA) is a virulence indicator used to identify the pathogenicity of the Aeromonas strain. Targeting a pathogen's crucial virulence gene for detection is essential, as it determines the potential threat to the host. This study aimed to develop a gold nanoparticle (AuNP) probe for detecting the gene aer A in Aeromonas hydrophila among field samples. MATERIALS AND METHODS: Kidney samples among both healthy and sick Nile tilapias in five provinces of Luzon Island were collected for bacterial analysis...
December 2023: Journal of Advanced Veterinary and Animal Research
#18
JOURNAL ARTICLE
Martín Alejandro Urtasun, Cristian Dorati, Martín Cañás, María Silvina Bruzzone, Gustavo H Marín, Nasim Iusef Venturini, Perla Mordujovich Buschiazzo
OBJECTIVE: Conduct an analysis to determine the existence and updating of national essential medicines lists (EMLs) and clinical practice guidelines (CPGs) for the treatment of diabetes in Latin America and the Caribbean (LAC); and compare the medicines included in each country's list and guidelines both with each other and with those of the World Health Organization (WHO). METHODS: Cross-sectional study. EMLs and CPGs for diabetes were found on the websites of the Pan American Health Organization and national health authorities...
2024: Pan American Journal of Public Health
#19
M Á Gómez-Ríos, J A Sastre, X Onrubia-Fuertes, T López, A Abad-Gurumeta, R Casans-Frances, D Gómez-Ríos, J C Garzón, V Martínez-Pons, M Casalderrey-Rivas, M Á Fernández-Vaquero, E Martínez-Hurtado, R Martín-Larrauri, L Reviriego-Agudo, U Gutierrez-Couto, J García-Fernández, A Serrano-Moraza, L J Rodríguez Martín, C Camacho Leis, S Espinosa Ramírez, J M Fandiño Orgeira, M J Vázquez Lima, M Mayo-Yáñez, P Parente-Arias, J A Sistiaga-Suárez, M Bernal-Sprekelsen, P Charco-Mora
The Airway Management section of the Spanish Society of Anesthesiology, Resuscitation, and Pain Therapy (SEDAR), the Spanish Society of Emergency Medicine (SEMES), and the Spanish Society of Otorhinolaryngology and Head and Neck Surgery (SEORL-CCC) present the Guide for the comprehensive management of difficult airway in adult patients. Its principles are focused on the human factor, cognitive processes for decision-making in critical situations, and optimization in the progression of strategies application to preserve adequate alveolar oxygenation in order to enhance safety and the quality of care...
February 8, 2024: Revista española de anestesiología y reanimación
#20
M Á Gómez-Ríos, J A Sastre, X Onrubia-Fuertes, Teresa López, A Abad-Gurumeta, R Casans-Frances, D Gómez-Ríos, J C Garzón, V Martínez-Pons, M Casalderrey-Rivas, M Á Fernández-Vaquero, E Martínez-Hurtado, R Martín-Larrauri, L Reviriego-Agudo, U Gutierrez-Couto, J García-Fernández, A Serrano-Moraza, L J Rodríguez Martín, C Camacho Leis, S Espinosa Ramírez, J M Fandiño Orgeira, M J Vázquez Lima, M Mayo-Yáñez, P Parente-Arias, J A Sistiaga-Suárez, M Bernal-Sprekelsen, P Charco-Mora
The Airway Management section of the Spanish Society of Anesthesiology, Resuscitation, and Pain Therapy (SEDAR), the Spanish Society of Emergency Medicine (SEMES), and the Spanish Society of Otorhinolaryngology and Head and Neck Surgery (SEORL-CCC) present the Guide for the comprehensive management of difficult airway in adult patients. Its principles are focused on the human factor, cognitive processes for decision-making in critical situations, and optimization in the progression of strategies application to preserve adequate alveolar oxygenation in order to enhance safety and the quality of care...
February 8, 2024: Revista española de anestesiología y reanimación
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