Dawei Liao, Ke Peng, Yang Zhang, Huayue Liu, Zhongyuan Xia, Jian Guo, Fujiang Wei, Chen Chen, Xin Lv, Jianhua Tong, Xiaoshuang Li, Xianfeng Qu, Xiaobin Wang, Yingbin Wang, Shanshan Ou, Hong Liu, Xisheng Shan, Fuhai Ji
BACKGROUND: There is still a controversy about the superiority of liposomal bupivacaine (LB) over traditional local anesthetics in postoperative analgesia after thoracic surgery. This study aims to determine the effect of LB versus bupivacaine hydrochloride (HCl) for preoperative ultrasound-guided erector spinae plane block (ESPB) on postoperative acute and chronic pain in patients undergoing video-assisted thoracoscopic lung surgery. METHODS: This multicenter, randomized, double-blind, controlled trial will include 272 adult patients scheduled for elective video-assisted thoracoscopic lung surgery...
2024: Frontiers in Medicine