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JOURNAL ARTICLE
Jean-Baptiste Delaye, Olivier Le Tilly, Emmanuel Enard, Christine Collet, Patrick Emond, Diane Dufour-Rainfray
We performed a method comparison between the Fujirebio® Lumipulse G AMH assay and the Roche® Elecsys AMH assay using the same pediatric samples. We described full pediatric gender and age-specific reference ranges for AMH using the Fujirebio® AMH assay on the Lumipulse G 600 II. The study was performed on 281 plasma samples collected in tubes with lithium heparin. The samples were from patients (135 males and 146 females) aged from 3 days to 22 years collected at the University Hospital Center of Tours...
April 19, 2024: Annales de Biologie Clinique
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JOURNAL ARTICLE
Sébastien Mateo, Aymeric Guillot, Sonia Henkous, Anthony Gelis, Sébastien Daligault, Gilles Rode, Christian Collet, Franck Di Rienzo
Cervical spinal cord injury (SCI) causes dramatic sensorimotor deficits that restrict both activity and participation. Restoring activity and participation requires extensive upper limb rehabilitation focusing elbow and wrist movements, which can include motor imagery. Yet, it remains unclear whether MI ability is impaired or spared after SCI. We investigated implicit and explicit MI ability in individuals with C6 or C7 SCI (SCIC6 and SCIC7 groups), as well as in aged- and gender-matched controls without SCI...
April 9, 2024: Brain Research
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JOURNAL ARTICLE
Vanessa Costa de Sousa, Fátima Regina Nunes Sousa, Raquel Felipe Vasconcelos, Gisele Angelino Barreto, Conceição S Martins, Nilson Romero Dias, Sislana Costa, Maria Jennifer Chaves Bernardino, George de Almeida Silva, Nadine Linhares, Delane Gondim, Mirna Marques, Helliada Chaves, Karuza Alves, Renata Leitão, Gerly A C Brito, Maria Elenir Nobre Pinho Ribeiro, Paula Goes
To investigate de effect of PAb gel on the bone tissue of rats submitted to Bisphosphonate-related osteonecrosis of the jaws (BRONJ). Initially, 54 animals were submitted to BRONJ model by Zoledronic Acid (ZA) (0.1 mg/kg 3x/wk for 9 wk, ip), followed by the 1st upper left molar extraction at the 8th wk. After tooth removal, the animals were divided into 3 groups, ZA that received placebo gel or PAb gel that received 1% PAb gel, inside the dental alveolus. The control Group (CONTROL) received 0.1 mg/kg of 0...
April 8, 2024: Scientific Reports
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JOURNAL ARTICLE
Marie Herbein, Susana Barbosa, Ophélie Collet, Olfa Khalfallah, Marie Navarro, Marion Bailhache, Nicolas Iv, Bruno Aouizerate, Anne-Laure Sutter-Dallay, Muriel Koehl, Lucile Capuron, Pierre Ellul, Hugo Peyre, Judith Van der Waerden, Maria Melchior, Sylvana Côté, Barbara Heude, Nicolas Glaichenhaus, Laetitia Davidovic, Cedric Galera
There is growing evidence that in utero imbalance immune activity plays a role in the development of neurodevelopmental and psychiatric disorders in children. Mood dysregulation (MD) is a debilitating transnosographic syndrome whose underlying pathophysiological mechanisms could be revealed by studying its biomarkers using the Research Domain Criteria (RDoC) model. Our aim was to study the association between the network of cord serum cytokines, and mood dysregulation trajectories in offsprings between 3 and 8 years of age...
July 2024: Brain, behavior, & immunity health
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JOURNAL ARTICLE
Bruno Henrique Alvarenga, Izabel Cristina Rios, Francisco de Salles Collet E Silva, Edivaldo Massazo Utiyama
OBJECTIVE: To evaluate whether the rate of surgical complications is higher during the first semester of the General Surgery residency in the largest hospital complex in Latin America. During this period, students are expected to have less experience in carrying out procedures. METHODS: During a period of two years, all General Surgery resident doctors at the Hospital das Clínicas of the Faculty of Medicine of the University of São Paulo, made a notification of all the procedures they performed (n = 14...
April 3, 2024: Clinics
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JOURNAL ARTICLE
Camille O Muller, Angèle Metais, Nawale Boublay, Caroline Breuil, Sébastien Deligault, Franck Di Rienzo, Aymeric Guillot, Christian Collet, Pierre Krolak-Salmon, Arnaud Saimpont
When applied over the primary motor cortex (M1 ), anodal transcranial direct current stimulation (a-tDCS) could enhance the effects of a single motor imagery training (MIt) session on the learning of a sequential finger-tapping task (SFTT). This study aimed to investigate the effect of a-tDCS on the learning of an SFTT during multiple MIt sessions. Two groups of 16 healthy young adults participated in three consecutive MIt sessions over 3 days, followed by a retention test 1 week later. They received active or sham a-tDCS during a MIt session in which they mentally rehearsed an eight-item complex finger sequence with their left hand...
April 4, 2024: Journal of Sports Sciences
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JOURNAL ARTICLE
Koshiro Sakai, Tatyana Storozhenko, Takuya Mizukami, Hirofumi Ohashi, Frederic Bouisset, Atomu Tajima, Lieven van Hoe, Emanuele Gallinoro, Giulia Botti, Thabo Mahendiran, Sofie Pardaens, Sofie Brouwers, Samer Fawaz, Thomas R Keeble, John R Davies, Jeroen Sonck, Bernard De Bruyne, Carlos Collet
BACKGROUND: Two invasive methods are available to estimate microvascular resistance: bolus and continuous thermodilution. Comparative studies have revealed a lack of concordance between measurements of microvascular resistance obtained through these techniques. AIMS: This study aimed to examine the influence of vessel volume on bolus thermodilution measurements. METHODS: We prospectively included patients with angina with non-obstructive coronary arteries (ANOCA) undergoing bolus and continuous thermodilution assessments...
April 2, 2024: Catheterization and Cardiovascular Interventions
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JOURNAL ARTICLE
Anaïs Bertaud, Thierry Cens, Alain Chavanieu, Sébastien Estaran, Matthieu Rousset, Lisa Soussi, Claudine Ménard, Akelsso Kadala, Claude Collet, Sébastien Dutertre, Patrick Bois, Pascal Gosselin-Badaroudine, Jean-Baptiste Thibaud, Julien Roussel, Michel Vignes, Mohamed Chahine, Pierre Charnet
DSC1, a Drosophila channel with sequence similarity to the voltage-gated sodium channel (NaV), was identified over 20 years ago. This channel was suspected to function as a non-specific cation channel with the ability to facilitate the permeation of calcium ions (Ca2+). A honeybee channel homologous to DSC1 was recently cloned and shown to exhibit strict selectivity for Ca2+, while excluding sodium ions (Na+), thus defining a new family of Ca2+ channels, known as CaV4. In this study, we characterize CaV4, showing that it exhibits an unprecedented type of inactivation, which depends on both an IFM motif and on the permeating divalent cation, like NaV and CaV1 channels, respectively...
May 6, 2024: Journal of General Physiology
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REVIEW
Marie-Elise Martel, Amélie Leurs, David Launay, Hélène Behal, Aurélien Chepy, Aurore Collet, Sébastien Sanges, Eric Hachulla, Sylvain Dubucquoi, Luc Dauchet, Vincent Sobanski
OBJECTIVES: Estimate the global prevalence of anti-Ro52-kDa/SSA (TRIM21) autoantibodies in systemic sclerosis (SSc), and describe the associated clinical phenotype, through a systematic review and meta-analysis of published reports and new data from our French cohort. METHODS: Anti-TRIM21 seropositivity and associated SSc characteristics were assessed in a cross-sectional study including 300 patients of Lille University Hospital. A systematic review of the literature was performed in Pubmed and Embase, followed by a meta-analysis, using data on prevalence, clinical/demographical/biological characteristics of SSc patients and the type of assay used for anti-TRIM21 antibodies detection (PROSPERO n° CRD42021223719)...
March 28, 2024: Autoimmunity Reviews
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JOURNAL ARTICLE
Derk Frank, Eric Durand, Sandra Lauck, Douglas F Muir, Mark Spence, Mariuca Vasa-Nicotera, David Wood, Francesco Saia, Cristóbal A Urbano-Carrillo, Damien Bouchayer, Vlad Anton Iliescu, Christophe Saint Etienne, Florence Leclercq, Vincent Auffret, Lluis Asmarats, Carlo Di Mario, Aurelie Veugeois, Jiri Maly, Andreas Schober, Luis Nombela-Franco, Nikos Werner, Joan Antoni Gómez-Hospital, Julia Mascherbauer, Giuseppe Musumeci, Nicolas Meneveau, Thibaud Meurice, Felix Mahfoud, Federico De Marco, Tim Seidler, Florian Leuschner, Patrick Joly, Jean-Philippe Collet, Ferdinand Vogt, Emilio Di Lorenzo, Elmar Kuhn, Vicente Peral Disdier, Violetta Hachaturyan, Claudia M Lüske, Radka Rakova, Wilbert Wesselink, Jana Kurucova, Peter Bramlage, Gemma McCalmont
BACKGROUND AND AIMS: There is significant potential to streamline the clinical pathway for patients undergoing transcatheter aortic valve implantation (TAVI). The purpose of this study was to evaluate the effect of implementing BENCHMARK best practices on the efficiency and safety of TAVI in 28 sites in 7 European countries. METHODS: This was a study of patients with severe symptomatic aortic stenosis (AS) undergoing TAVI with balloon-expandable valves before and after implementation of BENCHMARK best practices...
March 30, 2024: European Heart Journal
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REVIEW
Laetitia Collet, Brunhilde Hanvic, Margherita Turinetto, Isabelle Treilleux, Nicolas Chopin, Olivia Le Saux, Isabelle Ray-Coquard
BRCA1/2 genes are part of homologous recombination (HR) DNA repair pathways in charge of error-free double-strand break (DSB) repair. Loss-of-function mutations of BRCA1/2 genes have been associated for a long time with breast and ovarian cancer hereditary syndrome. Recently, polyadenosine diphosphate-ribose polymerase inhibitors (PARPi) have revolutionized the therapeutic landscape of BRCA1/2 -mutated tumors, especially of BRCA1/2 high-grade serous ovarian cancer (HGSC), taking advantage of HR deficiency through the synthetic lethality concept...
2024: Frontiers in Oncology
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JOURNAL ARTICLE
Nastassja Burrini, Arnaud Pâris, Guillaume Collet, Pierre Lafite, Richard Daniellou
This study unveils an innovative method for synthesizing coumarin S -glycosides, employing original biocatalysts able to graft diverse carbohydrate structures onto 7-mercapto-4-methyl-coumarin in one-pot reactions. The fluorescence properties of the generated thio-derivatives were assessed, providing valuable insights into their potential applications in biological imaging or sensing. In addition, the synthesized compounds exhibited no cytotoxicity across various human cell lines. This research presents a promising avenue for the development of coumarin S -glycosides, paving the way for their application in diverse biomedical research areas...
March 16, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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JOURNAL ARTICLE
Domenico Piccolo, Irene Fusco, Giuliana Crisman, Tiziano Zingoni, Claudio Conforti
Background : Facial hypermelanosis is a major cosmetic issue that causes severe social embarrassment and psychological pain, particularly among Asians and dark-skinned individuals. Aim : This study assesses the safety and effectiveness of Q-switched 1064/532 nm nanosecond/picosecond lasers in removing benign hypermelanosis in dark-skinned individuals, evaluating the possible associated side effects. Material and methods : A total of 30 participants (80% females and 20% males) with Fitzpatrick skin types IV-V-VI who presented superficial benign hypermelanoses on the facial and décolleté area were enrolled...
March 12, 2024: Journal of Clinical Medicine
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JOURNAL ARTICLE
Pierre Sabouret, Emanuele Barbato, Gilles Montalescot, Giuseppe Biondi-Zoccai, Stéphane Manzo-Silberman
No abstract text is available yet for this article.
March 27, 2024: Minerva cardiology and angiology
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JOURNAL ARTICLE
Karine Amorim Fladzinski, Lorene Armstrong, Cintia Aparecida Dos Anjos, Leandro Taborda da Rocha, Obdulio Gomes Miguel, Marilis Dallarmi Miguel, Deise Prehs Montrucchio, Josiane de Fátima Gaspari Dias
The order Sapindales is comprised of nine families and in Brazil it is represented by six, including Rutaceae Juss., which constitutes the largest group of this order. A variety of species of Zanthoxylum L. are distributed throughout the country, and among them is the species Zanthoxylum kleinii (R.S. Cowan) P.G. Waterman, which is found in the states of Brazil. This study aimed to characterize the morphoanatomy of the leaf, petiole, rachis, and stem of the species Z. kleinii. Histochemical tests were performed, and the sections were visualized under optical and scanning electron microscopy...
March 27, 2024: Microscopy Research and Technique
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JOURNAL ARTICLE
Hong Anh Nguyen, Pierre Martre, Clothilde Collet, Xavier Draye, Christophe Salon, Christian Jeudy, Renaud Rincent, Bertrand Muller
In line with the growing demand for characterizing root system architecture (RSA) for genetic analyses and the difficulty to access plant roots in situ, high throughput root phenotyping (HTRP) platforms under controlled conditions are developed. However, an evaluation of their capacity to provide the same estimates of strictly identical root traits across platforms has never been achieved. We performed such an evaluation based on six major parameters of a RSA model, ArchiSimple using a diversity panel of 14 bread wheat cultivars in two HTRP platforms that use different growth media and non-destructive imaging systems and a conventional setup that use solid medium and destructive sampling...
March 23, 2024: Journal of Experimental Botany
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JOURNAL ARTICLE
Émile Dupuy, Jean-François Collet
No abstract text is available yet for this article.
March 2024: Médecine Sciences: M/S
#18
REVIEW
Veleka Allen, Aymeric Mahieu, Ellen Kasireddy, Walid Shouman, Mir-Masoud Pourrahmat, Jean-Paul Collet, Andriy Cherkas
BACKGROUND: Diagnosis of children with type 1 diabetes (T1D) imposes an unprecedented burden on children and their caregivers. OBJECTIVE: To assess the burden of T1D on children and their informal caregivers, both after a recent diagnosis or after a longer duration of disease. METHODS: A series of systematic literature reviews were performed to explore the burden of T1D on children with the disease and their primary informal caregivers, based on the time of diagnosis...
March 21, 2024: Diabetology & Metabolic Syndrome
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JOURNAL ARTICLE
Nicolas Richard, Antonin Derinck, Valérie Bridoux, Cloé Charpentier, Céline Savoye Collet, Guillaume Savoye
PURPOSE: Perianal fistulae are disabling complications of Crohn's Disease. Magnetic resonance imaging features could predict treatment response. This study aimed to determine which magnetic resonance imaging features were predictive of long-term clinical outcome in real life. METHODS: Consecutive patients with magnetic resonance imaging performed in a tertiary center were retrospectively analyzed. Clinical outcome was defined as a need for surgical drainage of perianal fistulae or hospitalization...
March 21, 2024: Abdominal Radiology
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REVIEW
Hejdi Gamst-Jensen, Lone Dragnes Brix, Marie Oxenbøll Collet, Anne Højager Nielsen
BACKGROUND: Traditional research methods often involve a lengthy process, but the emergence of flash mobs as an innovative data collection method offers the potential to gather substantial data within a short time frame. Flash mobs draw inspiration from the concept of large groups organizing through the internet or mobile devices to perform a prearranged action in public. In healthcare research, flash mobs serve as research organizing method to investigate clinically relevant questions on a large scale within a limited period...
March 21, 2024: Acta Anaesthesiologica Scandinavica
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