Kozo Kataoka, Akira Ouchi, Yusuke Suwa, Hidekazu Hirano, Toshifumi Yamaguchi, Yasuyuki Takamizawa, Marie Hanaoka, Kenta Iguchi, Shogen Boku, Ken Nagata, Taiji Koyama, Yasuhiro Shimada, Masafumi Inomata, Yusuke Sano, Junki Mizusawa, Tetsuya Hamaguchi, Yasumasa Takii, Shunsuke Tsukamoto, Atsuo Takashima, Yukihide Kanemitsu
Although phase III randomized controlled trials (RCTs) represent the most robust statistical approach for answering clinical questions, they require massive expenditures in terms of time, labor, and funding. Ancillary and supplementary analyses using RCTs are sometimes conducted as alternative approaches to answering clinical questions, but the available integrated databases of RCTs are limited. In this background, the Colorectal Cancer Study Group (CCSG) of the Japan Clinical Oncology Group (JCOG) established a database of ancillary studies integrating four phase III RCTs (JCOG0212, JCOG0404, JCOG0910 and JCOG1006) conducted by the CCSG to investigate specific clinicopathological factors in pStage II/III colorectal cancer (JCOG2310A)...
April 18, 2024: European Journal of Surgical Oncology