Alexander Gelbard, Celestine Wanjalla, Christopher T Wootten, Wonder P Drake, Anne S Lowery, David A Wheeler, Maria F Cardenas, Andrew G Sikora, Ravi R Pathak, Wyatt McDonnell, Simon Mallal, Mark Pilkinton
OBJECTIVES/HYPOTHESIS: Characterization of the localized adaptive immune response in the airway scar of patients with idiopathic subglottic stenosis (iSGS). STUDY DESIGN: Basic Science. METHODS: Utilizing 36 patients with subglottic stenosis (25 idiopathic subglottic stenosis [iSGS], 10 iatrogenic post-intubation stenosis [iLTS], and one granulomatosis with polyangiitis [GPA]) we applied immunohistochemical and immunologic techniques coupled with RNA sequencing...
June 30, 2020: Laryngoscope