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JOURNAL ARTICLE
Siyu Luo, Xiaochong Song, Jingjuan Wang, Xiaojia Huang
On-site specific capture is a critical step in accurate analysis of trace Pb(II) in environmental waters. In this connection, a new Pb(II)-imprinted polymer-based adsorbent (LIPA) was in-situ prepared in pipette tip and used as the extraction medium of laboratory-made portable three channels in-tip microextraction apparatus (TIMA). Density function theory was employed to verify the selection of functional monomers for the preparation of LIPA. The physical and chemical properties of the prepared LIPA were inspected with various characterization techniques...
May 19, 2023: Talanta
#22
JOURNAL ARTICLE
Zhuo Zhang, Duoli Zhang, Fang Wang, Jiao Liu, Yuhong Sun, Songyot Anuchapreeda, Singkome Tima, Zhangang Xiao, Suwit Duangmano
Melanoma is a common skin tumor that causes a high rate of mortality, especially in Europe, North America and Oceania. Immunosuppressants such as anti-PD-1 have been used in the treatment of malignant melanoma, however, nearly 60% of patients do not respond to these treatments. Sema4D, also called CD100, is expressed in T cells and tumor tissues. Sema4D and its receptor, Plexin-B1, play crucial roles in the process of immune regulation, angiogenesis, and tumor progression. The role of Sema4D in melanoma with anti-PD-1 resistance is poorly understood...
2023: PeerJ
#23
JOURNAL ARTICLE
Wei Zhang, Daphne P Guh, Tima Mohammadi, Reka E Pataky, Alexander C T Tam, Larry D Lynd, Annalijn I Conklin
We aimed to estimate the total health care costs attributable to prostate cancer (PCa) during care phases by age, cancer stage, tumor grade, and primary treatment in the first year in British Columbia (BC), Canada. Using linked administrative health data, we followed a cohort of men aged ≥ 50 years at diagnosis with PCa between 2010 and 2017 (Cohort 1) from the diagnosis date until the date of death, the last date of observation, or 31 December 2019. Patients who died from PCa after 1 January 2010, were selected for Cohort 2...
March 8, 2023: Current Oncology
#24
JOURNAL ARTICLE
Shengli Wan, Qingze Fan, Yuesong Wu, Jingqing Zhang, Gan Qiao, Nan Jiang, Jie Yang, Yuanzhi Liu, Jingyan Li, Sawitree Chiampanichayakul, Singkome Tima, Fei Tong, Songyot Anuchapreeda, Jianming Wu
Cancer is a serious threat to human health, and chemotherapy for cancer is limited by severe side effects. Curcumin (CUR) is a commonly used natural product for antitumor treatment without safety concerns. However, low bioavailability and poor tumor accumulation are great obstacles for its clinical application. Our previous research has demonstrated that platelet membrane-camouflaged nanoparticles can efficiently ameliorate the in vivo kinetic characteristics and enhance the tumor affinity of payloads. Nevertheless, the antitumor efficiency of this formulation still needs to be thoroughly investigated, and its drug release behavior is limited...
February 13, 2023: Pharmaceutics
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JOURNAL ARTICLE
Cecilia T Costiniuk, Joel Singer, Judy Needham, Yanbo Yang, Hong Qian, Catharine Chambers, Ann N Burchell, Hasina Samji, Ines Colmegna, Sugandhi Del Canto, Guy-Henri Godin, Muluba Habanyama, Christian Hui, Abigail Kroch, Enrico Mandarino, Shari Margolese, Carrie Martin, Maureen Owino, Tima Mohammadi, Wei Zhang, Sandra Pelaez, Colin Kovacs, Erika Benko, Branka Vulesevic, Curtis L Cooper, Aslam H Anis
Understanding the roots of Covid-19 vaccine hesitancy in at-risk groups, such as persons living with HIV (PLWH), is of utmost importance. We developed a modified Vaccine Hesitancy Scale (VHS) questionnaire using items from the National Advisory Committee on Immunization Acceptability Matrix. To examine factors associated with receiving COVID-19 vaccine and the link between vaccine attitudes and beliefs with vaccine behavior, PLWH were recruited via social media and community-based organizations (February-May 2022)...
February 4, 2023: AIDS and Behavior
#26
JOURNAL ARTICLE
Yael Eshet, Noam Tau, Sara Apter, Noam Nissan, Keren Levanon, Rinat Bernstein-Molho, Ofer Globus, Amit Itay, Tal Shapira, Cecilie Oedegaard, Malka Gorfine, Michal Eifer, Tima Davidson, Einav Gal-Yam, Liran Domachevsky
PURPOSE: Invasive lobular breast cancer (ILC) may be hard to detect using conventional imaging modalities and usually shows less avidity to 18F-FDG PET/CT. 68Ga-fibroblast activation protein inhibitor (FAPI) PET/CT has shown promising results in detecting non-18F-FDG-avid cancers. We aimed to assess the feasibility of detecting metastatic disease in patients with non-18F-FDG-avid ILC. METHODS: This prospective study included patients with metastatic ILC, infiltrative to soft tissues, which was not 18F-FDG avid...
January 16, 2023: Clinical Nuclear Medicine
#27
JOURNAL ARTICLE
Jennifer Ben Shimol, Ron Lewin, Zvi Symon, Barak Rosenzweig, Raya Leibowitz-Amit, Yael Eshet, Liran Domachevsky, Tima Davidson
BACKGROUND: Numerous papers have described 68Ga-prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT)'s sensitivity in identifying prostate cancer (PCa) recurrence. This study aimed to characterize the role of 68Ga-PSMA PET/CT in deciding to re-irradiate pelvic structures. METHODS: 68Ga-PSMA PET/CT scans performed at Sheba Medical Center over seven years in 113 men were reviewed. All had undergone radiation to the prostate (70, 61...
December 29, 2022: International Journal of Environmental Research and Public Health
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JOURNAL ARTICLE
Shengli Wan, Yuesong Wu, Qingze Fan, Gang Yang, Haiyang Hu, Singkome Tima, Sawitree Chiampanichayakul, Songyot Anuchapreeda, Jianming Wu
Cancer is a major threat to the health of humans. Recently, various natural products including curcumin (CCM) have attracted enormous interest for efficacious cancer therapy. However, natural therapeutic agents still encounter certain challenges such as rapid clearance, low bioavailability, and poor tumor targeting. Recently, the platelet membrane (PM) camouflaged nanoparticle has provided a promising solution for cancer targeting therapy. Nevertheless, only limited efforts have been dedicated to systematically explore the mechanism of affinity between PM bioinspired nanoparticles and various tumor cells...
November 26, 2022: Pharmaceutics
#29
Fátima Ladeira Mendes Duarte, Bárbara Pereira da Silva, Mariana Grancieri, Cíntia Tomaz Sant'Ana, Renata Celi Lopes Toledo, Vinícius Parzanini Brilhante de São José, Sidney Pacheco, Hércia Stampini Duarte Martino, Frederico Augusto Ribeiro de Barros
Correction for 'Macauba ( Acrocomia aculeata ) kernel has good protein quality and improves the lipid profile and short chain fatty acids content in Wistar rats' by Fátima Ladeira Mendes Duarte et al. , Food Funct. , 2022, 13 , 11342-11352, https://doi.org/10.1039/D2FO02047E.
December 15, 2022: Food & Function
#30
JOURNAL ARTICLE
Ohnmar Myint, Sakornniya Wattanapongpitak, Suchart Kothan, Chatchanok Udomtanakunchai, Singkome Tima, Montree Tungjai
The objective was to investigate the effect of 4-hydroxybenzoic acid (4-HBA) and 4-hydroxy-3-methoxybenzoic acid (Vanillic acid, VA) on p-glycoprotein (P-gp) activity in multidrug-resistant K562/Dox cancer cells. The cytotoxic and co-treatment with pirarubicin (Pira) were analyzed using a resazurin assay. A noninvasive functional spectrofluorometric technique was used to determine the kinetics of Pira uptake in living multidrug-resistant K562/Dox cancer cells. The three biological endpoints for determination of cellular energetic state included the activity of mitochondria, mitochondrial membrane potential (ΔΨm), and ATP levels...
2022: Toxicology Reports
#31
Yuanzhi Liu, Yilan Huang, Jingyan Li, Shengli Wan, Nan Jiang, Jie Yang, Sawitree Chiampanichayakul, Singkome Tima, Songyot Anuchapreeda, Jianming Wu
Background: The Platinum-based combination has been proven to have an outstanding effect on patients with platinum-sensitive recurrent ovarian cancer (PSROC), but the best scientific combination has not been established yet. The present study is aimed to seek the best treatment plan for PSROC. Methods: We did a systematic review and Bayesian network meta-analysis, during which lite before March 2022 were retrieved on PubMed, Embase, Web of Science, and Cochrane Central Registry of Controlled databases. We included randomized controlled clinical trials comparing chemotherapy combinations with other treatments for patients with PSROC...
2022: Frontiers in Pharmacology
#32
JOURNAL ARTICLE
Fah Chueahongthong, Singkome Tima, Sawitree Chiampanichayakul, Pornngarm Dejkriengkraikul, Siriporn Okonogi, Mathurada Sasarom, Soraya Rodwattanagul, Cory Berkland, Songyot Anuchapreeda
Doxorubicin (Dox) is the standard chemotherapeutic agent for acute myeloblastic leukemia (AML) treatment. However, 40% of Dox-treated AML cases relapsed due to the presence of leukemic stem cells (LSCs). Thus, poloxamer 407 and CKR- and EVQ-FLT3 peptides were used to formulate Dox-micelles (DMs) and DM conjugated with peptides (CKR and EVQ) for improving AML-LSC treatment. Results indicated that DMs with a weight ratio of Dox to P407 of 1:200 had a particle size of 23.3 ± 1.3 nm with a high percentage of Dox entrapment...
October 4, 2022: Pharmaceutics
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JOURNAL ARTICLE
Pilanee Vaithanomsat, Nutthamon Boonlum, Wantida Chaiyana, Singkome Tima, Songyot Anuchapreeda, Chanaporn Trakunjae, Waraporn Apiwatanapiwat, Phornphimon Janchai, Antika Boondaeng, Hataitip Nimitkeatkai, Amnat Jarerat
Mushrooms are incredibly valuable macro fungi that are an important and integral part of the ecosystem. In addition to being used as cuisine, mushrooms have been used for medicinal purposes for many centuries. This research applied a process for recovering β-glucan (BG) from the antler-type fruiting body of Ganoderma lucidum as well as tested the biological activities related to cosmeceutical applications. The characterization of complex structure was performed by fourier-transform infrared (FTIR) and nuclear magnetic resonance (MNR) spectroscopies...
October 7, 2022: Polymers
#34
JOURNAL ARTICLE
Khin TheNu Aye, Sakornniya Wattanapongpitak, Benjamaporn Supawat, Suchart Kothan, Chatchanok Udomtanakunchai, Singkome Tima, Montree Tungjai
The aim of this study was to determine the effects of pre-low-dose irradiation followed by gallic acid (GA) on cell viability and cellular energetic state of leukemic K562 and K562/Dox cells. The cells were irradiated with 0.02, 0.05, and 0.1 Gy of X-rays. For determining cell viability, pre-low-dose irradiation was followed by 10 or 100 µM GA at 24 h post-irradiation, and the cell viability was then determined at 48 h post-irradiation. For cellular energetic state, pre-low-dose irradiation was followed by 10 or 100 µM GA at 1...
September 29, 2022: Medical Oncology
#35
JOURNAL ARTICLE
Moran Gadot, Ido Arad, Eshetu G Atenafu, Meital Levartovsky, Orith Portnoy, Tima Davidson, Rachel Schor-Bardach, Raanan Berger, Raya Leibowitz
Immune checkpoint inhibitors (ICIs) are now the standard of care for metastatic urothelial carcinoma (mUC) patients. Our aim was to describe the activity of ICIs in mUC and find the clinical parameters associated with response. This is a retrospective, single-center chart review of mUC patients receiving ICIs. The overall survival (OS) was plotted using the Kaplan-Meier method and was compared using a log-rank test. Associations between the variables and responses were analyzed by univariate and multivariable analyses, using either logistic regression or a Chi-square/Fisher's exact test...
September 16, 2022: Pharmaceuticals
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JOURNAL ARTICLE
Shaimaa M Badr-Eldin, Hibah M Aldawsari, Usama A Fahmy, Osama A A Ahmed, Nabil A Alhakamy, Omar D Al-Hejaili, Alhanoof A Alhassan, Ghadeer A Ammari, Shouq I Alhazmi, Raghad M Alawadi, Rana Bakhaidar, Abdulmohsen J Alamoudi, Thikryat Neamatallah, Singkome Tima
Ellagic acid has recently attracted increasing attention regarding its role in the prevention and treatment of cancer. Surface functionalized nanocarriers have been recently studied for enhancing cancer cells' penetration and achieving better tumor-targeted delivery of active ingredients. Therefore, the present work aimed at investigating the potential of APA-functionalized emulsomes (EGA-EML-APA) for enhancing cytototoxic activity of EGA against human breast cancer cells. Phospholipon® 90 G: cholesterol molar ratio (PC: CH; X1 , mole/mole), Phospholipon® 90 G: Tristearin weight ratio (PC: TS; X2 , w / w ) and apamin molar concentration (APA conc...
August 21, 2022: International Journal of Molecular Sciences
#37
JOURNAL ARTICLE
Natsima Viriyaadhammaa, Suwit Duangmano, Aroonchai Saiai, Montree Tungjai, Pornngarm Dejkriengkraikul, Singkome Tima, Sawitree Chiampanichayakul, Jeffrey Krise, Songyot Anuchapreeda
Curcuma comosa has been used in traditional Thai medicine to treat menstrual cycle-related symptoms in women. This study aims to evaluate the diarylheptanoid drug modulator, t rans -1,7-diphenyl-5-hydroxy-1-heptene (DHH), in drug-resistant K562/ADR human leukemic cells. This compound was studied due to its effects on cell cytotoxicity, multidrug resistance (MDR) phenotype, P-glycoprotein (P-gp) expression, and P-gp function. We show that DHH itself is cytotoxic towards K562/ADR cells. However, DHH did not impact P-gp expression...
August 12, 2022: International Journal of Molecular Sciences
#38
JOURNAL ARTICLE
Louise G Køhler, Bastian Huwer, José Martín Pujolar, Malin Werner, Karolina Wikström, Anders Wernbo, Maria Ovegård, Cornelia Jaspers
This data article includes a qualitative and quantitative description of the gelatinous macrozooplankton community of the North Sea during January-February 2021. Sampling was conducted during the 1st quarter International Bottom Trawl Survey (IBTS) on board the Danish R/V DANA (DTU Aqua Denmark) and the Swedish R/V Svea (SLU Sweden), as part of the ichthyoplankton investigation during night-time. A total of 147 stations were investigated in the western, central and eastern North Sea as well as the Skagerrak and Kattegat...
October 2022: Data in Brief
#39
JOURNAL ARTICLE
Fabio Botelho, Karen Gripp, Natalie Yanchar, Abbie Naus, Dan Poenaru, Robert Baird, Eliane Reis, Leonildo Farias, Ana Gabriely Silva, Francisco Viana, José Armando Pessoa Neto, Sidney Silva, Karen Ribeiro, Luana Gatto, Matheus Daniel Faleiro, Miguel Godeiro Fernandez, Lucas Sousa Salgado, Natália Zaneti Sampaio, Matheus Daniel Faleiro, Anna Luiza Mendes, Rodrigo Vaz Ferreira, Luiz Marcião, Gabriel Canto, José Borges, Victor Araújo, Gabrielly Andrade, Joyce Braga, Lívia Bentes, Luís Pinto, Henry T Ndasi, Lahin M Amlani, Ghislain Aminake, Xavier Penda, Serge Tima, Aron Lechtig, Kiran J Agarwal-Harding, Marta Whyte, Melinda Fowler-Woods, Amanda Fowler-Woods, Geraldine Shingoose, Andrew Hatala, Felicia Daeninck, Ashley Vergis, Kathleen Clouston, Krista Hardy, Laure Djadje, Olga Mbougo Djoutsop, Adrien Tangmi Djabo, Ulrick Sidney Kanmounye, Vanessa Nono Youmbi, Patricia Kakobo, Olga Mbougo Djoutsop, Adrien Tangmi Djabo, Ulrick Sidney Kanmounye, Surafeal Tafesse, Bisrat Tamene, Zelalem Chimdesa, Eden Alemayehu, Birhanu Abera, Dawit Yifru, Fitsum Kifle Belachew, Abenezer Tirsit, Negussie Deyassa, Bente E Moen, Terje Sundstrøm, Morten Lund-Johansen, Mersha Abebe, Rabia Khan, Amha Mekasha, Sophie Soklaridis, Faizal Haji, Juventine Asingei, Eric P O'Flynn, Diarmuid T O'Donovan, Sophia C Masuka, Doreen Mashava, Faith V Akello, Mpoki M Ulisubisya, Helena Franco, Abdoulie Njai, Samuel Simister, Micelle Joseph, Pierre Woolley, Deeptiman James, Faye M Evans, Ekta Rai, Nobhojit Roy, Varun Bansal, Jyoti Kamble, Anna Aroke, Siddarth David, Deepa Veetil, Kapil Dev Soni, Martin Gerdin Wärnberg, Siddhesh Zadey, João Ricardo Nickenig Vissoci, Himanshu Iyer, Siddhesh Zadey, Ritika Shetty, Siddhesh Zadey, Anushka Jindal, Himanshu Iyer, Gabriel Ouma, Sayed Shah Nur Hussein Shah, Carrie Hinchman, Isaiah Michael Rayel, Myles Dworkin, Kiran J Agarwal-Harding, Elijah Mlinde, Lahin M Amlani, Collin J May, Leonard N Banza, Linda Chokotho, Kiran J Agarwal-Harding, Myles Dworkin, Foster Mbomuwa, Paul Chidothi, Claude Martin, William James Harrison, Kiran J Agarwal-Harding, Linda Chokotho, Samuel Paek, Lahin Amlani, Foster Mbomuwa, Paul Chidothi, Claude Martin, William James Harrison, Kiran J Agarwal-Harding, Linda Chokotho, Togo Adégné, Poudiougo Abdoulmouinou, Traoré Amadou, Traoré Youssouf, Konaté Madiassa, Dicko Moussa Younoussa, Samaké Moussa, Bah Amadou, Touré Hawa, Abramowitz Laurent, Damilola Alexander Jesuyajolu, Charles Arinze Okeke, Otomi Obuh, Damilola A Jesuyajolu, Peace E Ehizibue, Nnamdi E Ikemefula, Jamike O Ekennia-Ebeh, Abdulqudus A Ibraham, Obinna E Ikegwuonu, Thomas M Diehl, Gisèle Juru Bunogerane, Dan Neal, Alain Jules Ndibanje, Robin T Petroze, Edmond Ntaganda, Laurie Milligan, Lydia Cairncross, Francois Malherbe, Liana Roodt, Daniel K Kyengera, Nathan N O'Hara, David Stockton, Alemayehu Bedada, Marvin Hsiao, Unami Chilisa, Brianne Yarranton, Nkhabe Chinyepi, Georges Azzie, Jeongyoon Moon, Zachary Rehany, Mehrshad Bakhshi, Amy Bergeron, Nathalie Boulanger, Larry Watt, Evan G Wong, Natalie Pawlak, Christine Bierema, Emmanuel Ameh, Abebe Bekele, Maria F Jimenez, Kokila Lakhoo, Nobhojit Roy, Hernan Sacato, Girma Tefera, Doruk Ozgediz, Sudha Jayaraman, Ines Peric, George Youngson, Emmanuel Ameh, Eric Borgstein, Eric O'Flynn, Joana Simoes, Pamela A Kingsley, Lior Sasson, Hagi Dekel, Alona Raucher Sternfeld, Sagi Assa, Racheli Sion Sarid, Naizihijwa Joel Mnong'one, Godwin Godfrey Sharau, Stella Mihayo Mongella, William Goldstein Caryl, Bernard Goldman, Rajan Bola, Joseph Ngonzi, Fanan Ujoh, Raymond Bernard Kihumuro, Ronald Lett, Amanda Torquato, Clara Tavares, Gabriele Lech, Anja Džunic, Fanan Ujoh, Victoria Gusa, Rosemary Apeaii, Rafat Noor, Rajan Bola, Isaac Ohene Guyan, Jan Christilaw, Stephen Hodgins, Ronald Lett, Catherine Binda, Kayoung Heo, Samuel Cheng, Hannah Foggin, Grace Hu, Sheila Lam, Lydia Feng, Alisha Labinaz, Jayd Adams, Rachel Livergant, Sacha Williams, Tamilarasy Vasanthakumaran, Youcef Lounes, Juan Mata, Philip Hache, Christian Schamberg-Bahadori, Adaw Monytuil, Emmanuel Mayom, Shahrzad Joharifard, Émilie Joos, Amy Paterson, Salome Maswime, Anneli Hardy, Rupert M Pearse, Bruce M Biccard, Mina Salehi, Irena Zivkovic, Sukhdeep Jatana, Shahrzad Joharifard, Émilie Joos, Michael J Flores, Kelsey E Brown, Heather J Roberts, Claire A Donnelley, Ericka P von Kaeppler, Edmund Eliezer, Billy Haonga, Saam Morshed, David W Shearer
No abstract text is available yet for this article.
July 2022: Canadian Journal of Surgery. Journal Canadien de Chirurgie
#40
JOURNAL ARTICLE
Fang Wang, Liqiong Yang, Mintao Xiao, Zhuo Zhang, Jing Shen, Songyot Anuchapreeda, Singkome Tima, Sawitree Chiampanichayakul, Zhangang Xiao
As immune checkpoint inhibitors (ICIs) continue to advance, more evidence has emerged that anti-PD-1/PD-L1 immunotherapy is an effective treatment against cancers. Known as the programmed death ligand-1 (PD-L1), this co-inhibitory ligand contributes to T cell exhaustion by interacting with programmed death-1 (PD-1) receptor. However, cancer-intrinsic signaling pathways of the PD-L1 molecule are not well elucidated. Therefore, the present study aimed to evaluate the regulatory network of PD-L1 and lay the basis of successful use of anti-PD-L1 immunotherapy in acute myeloid leukemia (AML)...
July 6, 2022: Scientific Reports
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