Claire Edmondson, Nicole Westrupp, Christopher Short, Paul Seddon, Catherine Olden, Colin Wallis, Malcolm Brodlie, Francis Baxter, Jonathan McCormick, Susan MacFarlane, Richard Brooker, Margaret Connon, Salim Ghayyda, Lesley Blaikie, Rebecca Thursfield, Lynsey Brown, April Price, Erin Fleischer, Daniel Hughes, Christine Donnelly, Mark Rosenthal, John Wallenburg, Keith Brownlee, Eric W F W Alton, Andrew Bush, Jane C Davies
BACKGROUND: Handheld spirometry allows monitoring of lung function at home, of particular importance during the COVID-19 pandemic. Pediatric studies are unclear on whether values are interchangeable with traditional, clinic-based spirometry. We aimed to assess differences between contemporaneous, home (unsupervised) and clinic (supervised) spirometry and the variability of the former. The accuracy of the commercially available spirometer used in the study was also tested. METHODS: Data from participants in the Clinical Monitoring and Biomarkers to stratify severity and predict outcomes in children with cystic fibrosisc (CLIMB-CF) Study aged ≥ 6 years who had paired (±1 day) clinic and home forced expiratory volume in 1 s (FEV1 ) readings were analyzed...
July 28, 2023: Pediatric Pulmonology