Dario Arnaldi, Pietro Mattioli, Matteo Pardini, Silvia Morbelli, Elena Capriglia, Annalisa Rubino, Valter Rustioni, Michele Terzaghi, Elisa Casaglia, Alessandra Serra, Michela Figorilli, Claudio Liguori, Mariana Fernandes, Fabio Placidi, Luca Baldelli, Federica Provini, Luigi Ferini-Strambi, Sara Marelli, Giuseppe Plazzi, Elena Antelmi, Valerio Brunetti, Enrica Bonanni, Monica Puligheddu
INTRODUCTION: Idiopathic/isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is considered the prodromal stage of alpha-synucleinopathies. Thus, iRBD patients are the ideal target for disease-modifying therapy. The risk FActoRs PREdictive of phenoconversion in iRBD Italian STudy (FARPRESTO) is an ongoing Italian database aimed at identifying risk factors of phenoconversion, and eventually to ease clinical trial enrollment of well-characterized subjects. METHODS: Polysomnography-confirmed iRBD patients were retrospectively and prospectively enrolled...
July 27, 2023: European Journal of Neurology