Jeongmin Han, Sumi Choi, Jinwoo Hong, Dayeong Gang, Seunghoon Lee, Kwangsoo Shin, Junghyeon Ko, Jeong-Uk Kim, Nathaniel S Hwang, Young-Hyeon An, Minsu Gu, Su-Hwan Kim
Polyphenols have been investigated for their potential to mitigate inflammation in the context of atopic dermatitis (AD). In this study, epigallocatechin-3-gallate (EGCG)-based carbon dots (EGCG@CDs) were developed to enhance transdermal penetration, reduce inflammation, recapitulate superoxide dismutase (SOD) activity, and provide antimicrobial effects for AD treatment. The water-soluble EGCG@CDs in a few nanometers size exhibit a negative zeta potential, making them suitable for effective transdermal penetration...
April 30, 2024: ACS Applied Materials & Interfaces