keyword
https://read.qxmd.com/read/38708735/fast-track-interventions-for-hiv-and-aids-epidemic-control-among-key-populations-a-rapid-review
#1
REVIEW
Zamasomi P B Luvuno, Ebenezer Wiafe, NomaKhosi Mpofana, Makgobole M Urusla, Celenkosini T Nxumalo
BACKGROUND: Targeted interventions for key populations remain critical for realisation of epidemic control for human immunodeficiency virus (HIV) infection because of the causal relationship between HIV infection in the general population and among key population groups. AIM: To consolidate evidence on the fast-track interventions towards achieving HIV epidemic control among key populations. METHODS: A rapid scoping review was conducted using the methodological framework by Arksey and O' Malley...
April 8, 2024: African Journal of Primary Health Care & Family Medicine
https://read.qxmd.com/read/38702944/a-short-review-on-deciphering-vyadhikshamatva-insights-from-hla-b27-ankylosing-spondylitis-relation
#2
JOURNAL ARTICLE
Athul T P, Meena S Deogade, Tanuja M Nesari, Athira Ramachandran
OBJECTIVES: Various aspects of the concept of Vyadhikshamatva have been thoroughly explored, highlighting its profound significance in resisting disease manifestation, particularly in the context of Ankylosing spondylitis. Investigated the relationship between HLA-B27 and Ankylosing spondylitis (AS) by examining current knowledge and hypotheses Furthermore, efforts were made to portray the influence of prakruti (constitution) and balam (strength) on disease manifestation and progression...
May 6, 2024: Journal of Complementary & Integrative Medicine
https://read.qxmd.com/read/38702164/the-relevance-of-naturopathy-as-a-therapeutic-tool-in-the-modern-era-a-narrative-review
#3
JOURNAL ARTICLE
Sumnalata Ma Dewangan, Braj Bhushan Kumar
BACKGROUND: There are numerous reports of remarkable recoveries from diseases through drugless healing systems. In an effort to enhance the understanding of naturopathic therapies, the author, a renowned BNYS doctor specializing in naturopathy, yoga, nutrition, and wellness, aims to explain the importance of drugless therapies in various disease conditions. OBJECTIVE: To provide a comprehensive overview of the relevance and efficacy of naturopathy as a therapeutic tool in modern healthcare...
May 3, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38700927/enhancing-control-over-nitric-oxide-photorelease-via-a-molecular-keypad-lock
#4
JOURNAL ARTICLE
Hani M Elbeheiry, Martin Schulz
Based on Boolean logic, molecular keypad locks secure molecular information, typically with an optical output. Here we investigate a rare example of a molecular keypad lock with a chemical output. To this end, the light-activated release of biologically important nitric oxide from a ruthenium complex is studied, using proton concentration and photon flux as inputs. In a pH-dependent equilibrium, a nitritoruthenium(II) complex is turned into a nitrosylruthenium(II) complex, which releases nitric oxide under irradiation with visible light...
May 3, 2024: Chemistry: a European Journal
https://read.qxmd.com/read/38695420/quality-of-life-after-necrotizing-enterocolitis-an-integrative-review
#5
REVIEW
Breno Oliveira Marques, Ana Beatriz Ferreira Gusmão, Luana Leal Gonzaga, Gabriela Garcia de Carvalho Laguna, Níkolas Brayan da Silva Bragas, Camila da Palma Maltez Monção, Natália Oliveira E Silva
OBJECTIVE: To describe the long-term health outcomes of neonates affected by necrotizing enterocolitis (NEC) and its implications for quality of life. DATA SOURCE: This is an integrative review, conducted by searching the literature in the following databases: Virtual Health Library (BVS), Latin American and Caribbean Health Sciences Literature (LILACS), Medical Literature Analysis and Retrieval System Online (MEDLINE), and PubMed, using Health Sciences Descriptors (DeCS): "necrotizing enterocolitis," "quality of life," and "prognosis" combined with the Boolean operators AND and OR: "quality of life" OR "prognosis...
2024: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://read.qxmd.com/read/38691548/a-network-based-modeling-framework-reveals-the-core-signal-transduction-network-underlying-high-carbon-dioxide-induced-stomatal-closure-in-guard-cells
#6
JOURNAL ARTICLE
Xiao Gan, Palanivelu Sengottaiyan, Kyu Hyong Park, Sarah M Assmann, Réka Albert
Stomata are pores on plant aerial surfaces, each bordered by a pair of guard cells. They control gas exchange vital for plant survival. Understanding how guard cells respond to environmental signals such as atmospheric carbon dioxide (CO2) levels is not only insightful to fundamental biology but also relevant to real-world issues of crop productivity under global climate change. In the past decade, multiple important signaling elements for stomatal closure induced by elevated CO2 have been identified. Yet, there is no comprehensive understanding of high CO2-induced stomatal closure...
May 1, 2024: PLoS Biology
https://read.qxmd.com/read/38690007/theories-determinants-and-intervention-models-and-approaches-on-inequalities-of-undernutrition-amongst-under-fives-a-literature-review
#7
JOURNAL ARTICLE
Kehinde Kazeem Kanmodi, Jimoh Amzat, Kafayat Aminu
BACKGROUND AND AIMS: One of the greatest public health problems of the 21st century is undernutrition in children under the age of 5 years (CAUFY). Globally, over 232 million CUAFY are undernourished and approximately 45% of mortality in this population are undernutrition-induced. This paper reviewed and critically explained the factors perpetuating undernutrition in CUAFY in the global space. It further explained the multi-level determinants that influence health inequalities and consequently exacerbate undernutrition amongst CUAFY globally...
May 2024: Health Science Reports
https://read.qxmd.com/read/38689747/relative-carcinogenicity-of-tacrolimus-vs-mycophenolate-after-solid-organ-transplantation-and-its-implications-for-liver-transplant-care
#8
JOURNAL ARTICLE
Dorothy Liu, Mark M Youssef, Josephine A Grace, Marie Sinclair
BACKGROUND: De novo malignancy is a leading cause of late morbidity and mortality in liver transplant recipients. Cumulative immunosuppression has been shown to contribute to post-transplant malignancy (PTM) risk. There is emerging evidence on the differential carcinogenic risk profile of individual immunosuppressive drugs, independent of the net effect of immunosuppression. Calcineurin inhibitors such as tacrolimus may promote tumourigenesis, whereas mycophenolic acid (MPA), the active metabolite of mycophenolate mofetil, may limit tumour progression...
April 27, 2024: World Journal of Hepatology
https://read.qxmd.com/read/38689618/analysis-of-the-virtual-healthcare-model-in-latin-america-a-systematic-review-of-current-challenges-and-barriers
#9
REVIEW
Alejandro De La Torre, Peter Diaz, Rafael Perdomo
BACKGROUND: The virtual care model can be used in all aspects of healthcare, such as prevention, diagnosis, treatment, and follow-up of most medical and surgical conditions. The objective of this study was to identify the current barriers to implementing and consolidating the virtual healthcare model, of "telemedicine", in Latin American countries. METHODS: A systematic review was conducted through four databases: PubMed, Scopus, Web of Science, and Virtual Health, including articles in Spanish, Portuguese, and English...
2024: MHealth
https://read.qxmd.com/read/38685841/the-confounding-role-of-graft-versus-host-disease-in-animal-models-of-cancer-immunotherapy-a-systematic-review
#10
JOURNAL ARTICLE
Hami Ashraf, Mohammad Heydarnejad, Farid Kosari
BACKGROUND: Cancer immunotherapy has emerged as a transformative approach for treating various malignancies, including melanoma, lung cancer, breast cancer, and leukemia. Animal models have been instrumental in elucidating the mechanisms and potential of these therapies. However, graft-versus-host disease (GVHD) is an inherent challenge in these studies, primarily because the introduction of foreign immune cells or tissues often triggers immune responses. METHODS: A detailed systematic search was conducted across various scientific databases, including PubMed, Scopus, Embase, and Web of Science...
March 1, 2024: Archives of Iranian Medicine
https://read.qxmd.com/read/38680158/current-trends-and-spatial-temporal-dynamics-of-veterinary-dentistry-research-a-scientometric-study
#11
JOURNAL ARTICLE
Daniel Alvitez-Temoche, Elca Del Aguila, Diego Galarza-Valencia, Iván Calderón, Fran Espinoza-Carhuancho, Josmel Pacheco-Mendoza, Frank Mayta-Tovalino
BACKGROUND AND AIM: Understanding dental care in dogs has made remarkable progress in veterinary medicine. Therefore, this study aimed to analyze the academic literature published in veterinary dentistry from 1990 to 2023. MATERIALS AND METHODS: A descriptive study was conducted using a scientometric approach and metadata from the Web of Science database. A search strategy adapted for this database was developed using MeSH and Emtree terms and the Boolean operators AND and OR...
March 2024: Veterinary World
https://read.qxmd.com/read/38677355/unlocking-hope-anti-vegfr-inhibitors-and-their-potential-in-glioblastoma-treatment
#12
REVIEW
Ali Berro, Ahmad Assi, Mohamad Farhat, Lea Hatoum, Jean-Pierre Saad, Rami Mohanna, Anna Maria Antoun Bechara, Gilles Prince, Maria Catherine Rita Hachem, Ziad Zalaquett, Hampig-Raphael Kourie
PURPOSE: This systematic review summarizes evidence of VEGFR gene mutations and VEGF/VEGFR protein expression in glioblastoma multiforme (GBM) patients, alongside the efficacy and safety of anti-VEGFR tyrosine kinase inhibitors (TKIs) for GBM treatment. METHODS: A comprehensive literature review was conducted using PubMed up to August 2023. Boolean operators and MeSH term "glioma," along with specific VEGFR-related keywords, were utilized following thorough examination of existing literature...
April 25, 2024: Critical Reviews in Oncology/hematology
https://read.qxmd.com/read/38676342/time-controlled-authentication-strategies-for-molecular-information-transfer
#13
JOURNAL ARTICLE
Minghao Hu, Mengyao Yang, Xianzhi Cheng, Tongbo Wu
Modern cryptography based on computational complexity theory is mainly constructed with silicon-based circuits. As DNA nanotechnology penetrates the molecular domain, utilizing molecular cryptography for data access protection in the biomolecular domain becomes a unique approach to information security. However, building security devices and strategies with robust security and compatibility is still challenging. Here, this study reports a time-controlled molecular authentication strategy using DNAzyme and DNA strand displacement as the basic framework...
April 26, 2024: Small
https://read.qxmd.com/read/38674317/microbiota-transplantation-as-an-adjunct-to-standard-periodontal-treatment-in-periodontal-disease-a-systematic-review
#14
REVIEW
Cherry Erlin Lindo, James Sebastian, Karina Natalie Kuntjoro, Valencia Audrey Halim, Fatimah Maria Tadjoedin, Sandra Olivia Kuswandani, Benso Sulijaya
Periodontitis is a disease linked to severe dysbiosis of the subgingival microbiome. The treatment of periodontitis aims to change the dysbiosis environment to a symbiosis environment. We hypothesized that oral microbiota transplantation can lead to a significant improvement in periodontitis. Therefore, the aim of this study was to determine the effectiveness of microbiota transplantation after standard periodontal treatment in periodontitis patients. The search strategy was carried out by using the Boolean term "AND" to combine the keywords, which were "periodontitis AND microbiota transplantation"...
April 21, 2024: Medicina
https://read.qxmd.com/read/38673404/world-trends-in-dental-ergonomics-research-a-bibliometric-analysis
#15
REVIEW
Wita Anggraini, Dewi Ranggaini, Annisaa Putri Ariyani, Indrani Sulistyowati
Dental ergonomics provides an overview of dentists' work efficiency. The objective of this study was to obtain quantitative information and produce a visualization of the network of scientific publications on the topic of ergonomics and dentistry using bibliometric analysis. Data mining was conducted using the Scopus database and Boolean expressions (ergonom* AND dentist*) on 14 April 2023. Data extraction and analysis were performed using Open Refine version 3.5.2., VOSviewer version 1.6.17., VOSviewer thesaurus, Microsoft Excel, and Tableau Professional version 2020...
April 17, 2024: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/38669691/linear-codes-for-hyperdimensional-computing
#16
JOURNAL ARTICLE
Netanel Raviv
Hyperdimensional computing (HDC) is an emerging computational paradigm for representing compositional information as high-dimensional vectors and has a promising potential in applications ranging from machine learning to neuromorphic computing. One of the long-standing challenges in HDC is factoring a compositional representation to its constituent factors, also known as the recovery problem. In this letter, we take a novel approach to solve the recovery problem and propose the use of random linear codes. These codes are subspaces over the Boolean field and are a well-studied topic in information theory with various applications in digital communication...
April 17, 2024: Neural Computation
https://read.qxmd.com/read/38667452/accuracy-of-artificial-intelligence-models-in-dental-implant-fixture-identification-and-classification-from-radiographs-a-systematic-review
#17
REVIEW
Wael I Ibraheem
Background and Objectives : The availability of multiple dental implant systems makes it difficult for the treating dentist to identify and classify the implant in case of inaccessibility or loss of previous records. Artificial intelligence (AI) is reported to have a high success rate in medical image classification and is effectively used in this area. Studies have reported improved implant classification and identification accuracy when AI is used with trained dental professionals. This systematic review aims to analyze various studies discussing the accuracy of AI tools in implant identification and classification...
April 11, 2024: Diagnostics
https://read.qxmd.com/read/38665843/a-concept-of-dual-responsive-prodrugs-based-on-oligomerization-controlled-reactivity-of-ester-groups-an-improvement-of-cancer-cells-versus-neutrophils-selectivity-of-camptothecin
#18
JOURNAL ARTICLE
Insa Klemt, Viktor Reshetnikov, Subrata Dutta, Galyna Bila, Rostyslav Bilyy, Itziar Cossío Cuartero, Andrés Hidalgo, Adrian Wünsche, Maximilian Böhm, Marit Wondrak, Leoni A Kunz-Schughart, Rainer Tietze, Frank Beierlein, Petra Imhof, Sabrina Gensberger-Reigl, Monika Pischetsrieder, Marlies Körber, Tina Jost, Andriy Mokhir
Many known chemotherapeutic anticancer agents exhibit neutropenia as a dose-limiting side effect. In this paper we suggest a prodrug concept solving this problem for camptothecin (HO-cpt). The prodrug is programmed according to Boolean "AND" logic. In the absence of H2 O2 (trigger T1), e.g. in the majority of normal cells, it exists as an inactive oligomer. In cancer cells and in primed neutrophils (high H2 O2 ), the oligomer is disrupted forming intermediate (inactive) lipophilic cationic species. These are accumulated in mitochondria (Mit) of cancer cells, where they are activated by hydrolysis at mitochondrial pH 8 (trigger T2) with formation of camptothecin...
April 24, 2024: RSC medicinal chemistry
https://read.qxmd.com/read/38658267/hyperspectral-and-multispectral-imaging-in-neurosurgery-a-systematic-literature-review-and-meta-analysis
#19
REVIEW
Giulio Anichini, Maria Leiloglou, Zepeng Hu, Kevin O'Neill, Daniel Elson
INTRODUCTION: The neuro-surgical community is witnessing a rising interest for surgical application of multispectral/hyperspectral imaging. Several potential technical applications of this optical imaging are reported, but the set-up is variable and so are the processing methods. We present a systematic review of the relevant literature on the topic. MATERIALS AND METHODS: A literature search based on the PRISMA principles was performed on PubMed, SCOPUS, and Web of Science, using MESH terms and Boolean operators...
April 12, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38656822/heteromultivalent-dna-enhances-the-assembly-yield-of-hybrid-nanoparticles-and-facilitates-dynamic-disassembly-for-bioanalysis-using-icp-ms
#20
JOURNAL ARTICLE
Lijie Du, Peng Yang, Lingying Xia, Changjia Hu, Fengyi Yang, Junbo Chen, Xiandeng Hou
To obtain enhanced physical and biological properties, various nanoparticles are typically assembled into hybrid nanoparticles through the binding of multiple homologous DNA strands to their complementary counterparts, commonly referred to as homomultivalent assembly. However, the poor binding affinity and limited controllability of homomultivalent disassembly restrict the assembly yield and dynamic functionality of the hybrid nanoparticles. To achieve a higher binding affinity and flexible assembly choice, we utilized the paired heteromultivalency DNA to construct hybrid nanoparticles and demonstrate their excellent assembly characteristics and dynamic applications...
April 24, 2024: Analytical Chemistry
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