Cristina Milillo, Eleonora Aruffo, Piero Di Carlo, Antonia Patruno, Marco Gatta, Annalisa Bruno, Melania Dovizio, Lisa Marinelli, Marilisa Pia Dimmito, Viviana Di Giacomo, Cecilia Paolini, Mirko Pesce, Patrizia Ballerini
BACKGROUND: Nanoplastics, an emerging form of pollution, are easily consumed by organisms and pose a significant threat to biological functions due to their size, expansive surface area, and potent ability to penetrate biological systems. Recent findings indicate an increasing presence of airborne nanoplastics in atmospheric samples, such as polystyrene (PS), raising concerns about potential risks to the human respiratory system. METHODS: This study investigates the impact of 800 nm diameter-PS nanoparticles (PS-NPs) on A549, a human lung adenocarcinoma cell line, examining cell viability, redox balance, senescence, apoptosis, and internalization...
2024: Frontiers in Public Health