Stephen C Moye, Sumanth Kidambi, James Y Lee, Teaghan H Cowles, Shane D Gilligan-Steinberg, Amelia Y Bryan, Rob Wilkerson, Y Joseph Woo, Michael R Ma
Single ventricle physiology (SVP) is used to describe any congenital heart lesion that is unable to support independent pulmonary and systemic circulations. Current treatment strategies rely on a series of palliation surgeries that culminate in the Fontan physiology, which relies on the single functioning ventricle to provide systemic circulation while passively routing venous return through the pulmonary circulation. Despite significant reductions in early mortality, the presence of atrioventricular valve (AVV) regurgitation is a key predictor of heart failure in these patients...
March 25, 2023: Annals of Biomedical Engineering