Ayano Ogawa, Yasunori Sasaki, Masahiro Naruse
In patients with clefts, the affection of other congenital malformations on the feeding is unclear. We investigated the other congenital malformations and nutritional intake of neonates with cleft lip and/or palate and examined their relationships associated with cleft type and laterality. The participants included 126 infants under treatment with a presurgical naso-alveolar molding (PNAM) or a Hotz-type plate. The survey items were gender, cleft type and side, presence and nature of other congenital malformations, birth weight and nutritional method at age of the fifth day...
January 21, 2023: Congenital Anomalies
Hojin Park, Haneul Kim, Yong-Jae Hwang, Seung-Ha Park
INTRODUCTION: In secondary cleft lip and nasal deformity (CLND) correction, structural grafts are commonly used to control the nasal tip and restore the symmetry of the ala. However, the septal cartilage in Asians often weak and small. Biocompatible absorbable materials are alternatives to autologous grafts. This study assessed the surgical outcomes and complications of poly lactic-co-glycolic acid (PLGA) plate grafts in secondary CLND correction. METHODS: This study was retrospectively analyzed for patients who underwent secondary rhinoplasty for unilateral CLND correction between March 2015 and November 2020...
January 5, 2023: Cleft Palate-craniofacial Journal
Eriya Shimada, Hiroyasu Kanetaka, Kensuke Yamauchi, Tetsu Takahashi, Kotaro Nochioka, Kaoru Igarashi
INTRODUCTION: Bone-anchored maxillary protraction (BAMP) was devised recently as a method of direct maxillary protraction using anchor plates implanted in the maxilla and mandible without involving the teeth. Although several reports have described orthognathic effects of BAMP on patients with cleft lip and palate (CLP) with skeletal crossbite, none has described a study of Japanese patients with CLP or of BAMP treatment effects on speech in patients with CLP. This study, by performing BAMP treatment, and by evaluating speech function and skeletal and soft tissues, is intended to clarify BAMP efficacy and safety for patients with unilateral CLP (UCLP) who have skeletal crossbite...
September 1, 2022: BMJ Open
Wen-Yu Meng, Yan-Qing Ma, Bing Shi, Ren-Kai Liu, Xiao-Ming Wang
BACKGROUND: Patients with unilateral cleft lip and palate were associated with different nasomaxillary complex from the normal population. Although the biomechanical effects of conventional rapid palatal expansion (Hyrax expansion) and bone-borne rapid palatal expansion (micro-implant-assisted expansion) in non-cleft patients have been identified by multiple studies, little is known in patients with unilateral cleft lip and palate. The purpose of this study was to investigate and compare the biomechanical effects of the conventional and bone-borne palatal expanders in a late adolescence with unilateral cleft lip and palate...
December 13, 2022: BMC Oral Health
Shayna P Avinoam, Haley R Kowalski, Bachar F Chaya, Pradip R Shetye
Presurgical infant orthopedic (PSIO) therapy has evolved in both its popularity and focus of treatment since its advent. Nasoalveolar molding, nasal elevators, the Latham appliance, lip taping, and passive plates are the modern treatment options offered by cleft teams. Many cleft surgeons also employ postsurgical nasal stenting (PSNS) after the primary lip repair procedure. The purpose of this study is to examine trends in current PSIO care as well as PSNS for the management of patients with cleft lip and palate...
November 2022: Journal of Craniofacial Surgery
Sofia Ahsanuddin, Mairaj Ahmed, Leslie Slowikowski, Jenna Heitzler
Presurgical Nasoalveolar Molding (NAM) is an adjunctive treatment modality designed to reorient misaligned tissue structures and nasal cartilage in cleft lip and/or palate (CL/P) patients. Recent advances in NAM therapy focus on modifications to the intraoral molding plate or nasal stent intended to improve treatment outcomes, ease of use, compliance, and cost-effectiveness. Notably, 3D technological advancements have been employed to design NAM devices more efficiently and create objective, standardized means of measuring progressive morphological changes during therapy...
December 2022: Craniomaxillofacial Trauma & Reconstruction
Peiyang Zhang, Haizhou Tong, Yujie Chen, Binyi Zhou, Lin Fang, Zhenmin Zhao
Bone-borne trans-sutural distraction osteogenesis (TSDO) is widely used to treat midfacial hypoplasia in children with cleft lip and palate; however, its effects on the cranial base are still poorly understood. The authors aimed to study morphological changes in the cranial base after TSDO. Pre and postoperative computed tomography (CT) images of cleft lip and palate children with midfacial skeleton dysplasia who underwent TSDO were collected retrospectively, and their corresponding 3-dimensional models were measured...
October 31, 2022: Journal of Craniofacial Surgery
Vanessa de Couto Nascimento, Mariana Martins E Martins, Beatriz de Souza Vilella, Renato Faco, Hilde Timmerman, Hugo De Clerck, Daniela Garib, Oswaldo de Vasconcellos Vilella
INTRODUCTION: This study aimed to evaluate the influence of bone-anchored maxillary protraction (BAMP) on the oral health-related quality of life (OHRQOL) in subjects with complete unilateral cleft lip and palate (UCLP) and moderate-to-severe maxillary deficiency. METHODS: A longitudinal observational study was conducted with a sample of 20 patients (13 males, 7 females) aged 10-14 years (mean age, 11.8 years) with Goslon 3, 4, and 5. To assess the patient's perception of their OHRQOL, the Quality of Life Questionnaire for Orthosurgical Patients was administered in 2 stages: after the installation of the protraction plates (T1) and 18 months after the protraction therapy started (T2)...
October 12, 2022: American Journal of Orthodontics and Dentofacial Orthopedics
Parichehr Zarean, Paridokht Zarean, Florian M Thieringer, Andreas A Mueller, Sabine Kressmann, Martin Erismann, Neha Sharma, Benito K Benitez
Cleft lip and palate are one of the most common congenital craniofacial malformations. As an initial treatment, presurgical orthopedics is considered standard treatment at many cleft centers. Digital impressions are becoming feasible in cleft care. Computer-aided design (CAD) and three-dimensional (3D) printing are manufacturing standards in dentistry. The assimilation of these technologies has the potential to alter the traditional workflow for the fabrication of customized presurgical orthopedic plates. We present a digital workflow comprising three steps: 3D digital image acquisition with an intraoral scanner, open-source CAD modeling, and point-of-care 3D printing for the fabrication of personalized passive presurgical plates for newborns with cleft lip and palate...
August 20, 2022: Children
Sara Sabir, Hasnaa Rokhssi, Noureddine Famma, Mohamed Azhari, Oussama Bentahar
OBJECTIVE: This study aimed to propose digitally designed impression trays, for newborns with cleft lip and palate (CLP) defects, using the computer-assisted design and manufacturing (CAD/CAM) technique, based on measurements of width, length, and height made on processed and scanned plaster models. Thus, we will describe the different software and concepts that can be used for the design of these impression trays. DESIGN: A total of 59 plaster casts of newborn patients with CLP were collected and then scanned...
August 9, 2022: Cleft Palate-craniofacial Journal
Jenn J Park, Ricardo Rodriguez Colon, Fernando D Arias, Matteo Laspro, Bachar F Chaya, Danielle H Rochlin, David A Staffenberg, Roberto L Flores
OBJECTIVE: Primary cleft nasal repair can include septal reconstruction. We hypothesize that primary cleft septoplasty and adult septoplasty have fundamental differences that render these procedures as distinct surgical entities. DESIGN: Systematic review of the PubMed, Cochrane, and Embase databases performed on pediatric cleft and general adult septoplasty techniques through December 2021. (PROSPERO ID CRD42022295763). MAIN OUTCOME MEASURES: Collected data included information on septal dissection, septal detachment, and management of the bony and cartilaginous septum...
July 15, 2022: Cleft Palate-craniofacial Journal
Prabhat Kumar Chaudhari, Kunaal Dhingra, Harnoor Dhillon, Edlira Zere, Jitender Sharan, Amit Kumar, Mohammad Khursheed Alam, Anand Marya
OBJECTIVE: This review will compare the efficacy of nasoalveolar molding plates fabricated using a digital workflow and compare these with conventional fabrication methods or no intervention in infants with cleft lip or palate. INTRODUCTION: Nasoalveolar molding reduces the severity of the orofacial defect in infants with cleft lip or palate using a series of adaptable plates for the maxillary arch. The conventional method needs multiple patient visits at short intervals for treatment...
June 10, 2022: JBI evidence synthesis
Andrea Rei Estacio Salazar, Yasumitsu Kodama, Ryutaro Yuki, Rei Ominato, Takahiro Nagai, Momoko Watanabe, Akane Yamada, Ryota Kobayashi, Kaya Ichikawa, Jun Nihara, Akihiko Iida, Kazuhiro Ono, Isao Saito, Ritsuo Takagi
OBJECTIVE: This study aimed to determine if the change in technique of soft palate closure or timing of hard palatal repair induced occlusal changes in patients with complete unilateral cleft lip and palate (CUCLP). DESIGN: Retrospective study. SETTINGS: A medical and dental hospital in Japan. SUBJECTS: A total of 96 patients with CUCLP treated with 2-stage palatoplasty were included in the study and categorized into 3 groups (G1, G2, and G3) according to the protocol used...
April 25, 2022: Cleft Palate-craniofacial Journal
HyeRan Choo, Seong-Hun Kim, Hyo-Won Ahn, Christian F Poets, Kyu-Rhim Chung
Since the emergence of neonatal infant orthodontics for treatments of cleft lip and palate with or without Robin sequence (RS) in Europe in the 1950s, advancements in design and scope of its application have been remarkable. As the first institution to adopt orthodontic airway plate (OAP) treatment in the United States in 2019, we saw a need for innovation of the original design to streamline the most labor-intensive and time-consuming aspects of OAP utilization. A solution is introduced using a systematic split expansion mechanism to re-size the OAP periodically to accommodate the neonate's maxillary growth...
July 25, 2022: Korean Journal of Orthodontics
Noha A El-Ashmawi, Mona M Salah Fayed, Amr El-Beialy, Ahmed E Fares, Khaled H Attia
OBJECTIVE: The aim is to compare the facial esthetics following nasoalveolar molding (NAM) versus computer-aided design NAM (CAD/NAM) in patients with bilateral cleft lip/palate (CLP). DESIGN: The trial is a randomized comparative trial with a 1:1 allocation ratio. PARTICIPANTS: Thirty infants with bilateral complete cleft lip and palate were recruited. INTERVENTIONS: Patients were randomized between NAM and CAD/NAM groups...
April 14, 2022: Cleft Palate-craniofacial Journal
Sreeya Shankari Kandaswamy, Shanmugasundaram Somasundaram, Sneha Pendem, V B Krishna Kumar Raja
Aim: The aim of this study was to evaluate the maxillary anatomy in patients with cleft maxillary hypoplasia using computed tomogram. Materials and Methods: A cross-sectional observational study was carried out in all cleft patients reporting to our department for the correction of secondary cleft deformities. A preoperative computed tomogram of the midface (from the superior orbital rim to the maxillary occlusal plane) was recorded to assess the parameters which evaluate the maxillary and pterygomaxillary anatomy in cleft maxillary hypoplasia patients...
March 2022: Journal of Maxillofacial and Oral Surgery
Seema Deshmukh, Prashanth Sadashiva Murthy, Birti Singh, Inshiya Contractor
AIM: To assess the influence of virtual reality (VR) in parent acceptance of the pre-surgical nasoalveolar molding (PNAM) as a pre surgical care to the cleft lip and palate affected infants. MATERIAL AND METHODS: Descriptive Cross sectional pilot study design was planned to assess the pre surgical management of the cleft lip and palate. Twenty parents/caregivers of the infants were randomly divided into two groups. Twelve participants received education through conventional education module (Group I) using verbal explanation supported by the photographs...
April 9, 2022: Special Care in Dentistry
Taimoor Al Balushi, Meera Sahib, Zahra Al Abduwani, P S Viswapurna, Mohammad Zeinalddin
Cleft lip and/or palate are one of the most common birth defects around the world. This cross sectional study aimed to study characteristic of cleft lip and plate cases attended Khaula Hospital Cleft Center. METHODS: The data were collected from Plastic Surgery Department of Khaula Hospital Muscat, Oman, between years 2010 and 2019. Data was collected using a form that included demographic distribution of patients, gender, age, birth weight, region, age when first attended hospital, associated congenital anomalies and syndromes, type of delivery, mother consumption of Folic Acid, types of cleft lip/palate, and surgeries done...
March 2022: Journal of Craniofacial Surgery
Jacob I Reynolds, Ross A Vitek, Peter G Geiger, Brian P Johnson
Intercellular signaling drives human development, but there is a paucity of in vitro models that recapitulate important tissue architecture while remaining operationally simple and scalable. As an example, formation of the upper lip and palate requires the orchestrated proliferation and fusion of embryonic facial growth centers and is dependent on paracrine epithelial-mesenchymal signaling through multiple pathways including the Sonic Hedgehog (SHH), transforming growth factor-beta (Tgf-β), bone morphogenic protein (BMP), and epidermal growth factor (EGF) pathways...
2022: Methods in Molecular Biology
Benito K Benitez, Andrzej Brudnicki, Zbigniew Surowiec, Ravi K Singh, Prasad Nalabothu, Dieter Schumann, Andreas A Mueller
The study aims at assessing wound healing and safety of single-stage two-layers continuous closure in patients with unilateral cleft lip and palate (UCLP). In this retrospective, descriptive cohort study, we assessed wound healing without fistula formation at 1, 3, and 6 months after a single-stage two-layer UCLP repair, in which the midline suture is continuously circular all along the oral and nasal sides. We examined lengths of hospital stay and the incidence of intra- and postoperative adverse events. Furthermore, we compared the cleft width at birth and on the day of surgery, after presurgical orthopaedics...
August 3, 2021: Journal of Cranio-maxillo-facial Surgery
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