Alexandra N Demetriou, Frances Chow, David W Craig, Michelle G Webb, D Ryan Ormond, James Battiste, Arnab Chakravarti, Howard Colman, John L Villano, Bryan P Schneider, James K C Liu, Michelle L Churchman, Gabriel Zada
BACKGROUND: Glioblastoma exhibits aggressive growth and poor outcomes despite treatment, and its marked variability renders therapeutic design and prognostication challenging. The Oncology Research Information Exchange Network (ORIEN) database contains complementary clinical, genomic, and transcriptomic profiling of 206 glioblastoma patients, providing opportunities to identify novel associations between molecular features and clinical outcomes. METHODS: Survival analyses were performed using the Logrank test, and clinical features were evaluated using Wilcoxon and chi-squared tests with q -values derived via Benjamini-Hochberg correction...
2024: Neuro-oncology advances