Md Faysal, Zerrouki Dehbia, Mehrukh Zehravi, Sherouk Hussein Sweilam, M Akiful Haque, Kusuma Praveen Kumar, Rita D Chakole, Satish P Shelke, Swapna Sirikonda, Mohamed H Nafady, Sharuk L Khan, Firzan Nainu, Irfan Ahmad, Talha Bin Emran
Neurodegeneration, the decline of nerve cells in the brain, is a common feature of neurodegenerative disorders (NDDs). Oxidative stress, a key factor in NDDs such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and Huntington's disease can lead to neuronal cell death, mitochondria impairment, excitotoxicity, and Ca2+ stress. Environmental factors compromising stress response lead to cell damage, necessitating novel therapeutics for preventing or treating brain disorders in older individuals and an aging population...
June 1, 2024: Neurochemical Research