Bianca de Melo Santana, Giovana Marchini Armentano, Dayana Agnes Santos Ferreira, Camila Simões de Freitas, Marcela Sorelli Carneiro-Ramos, Amedea Barozzi Seabra, Myron Christodoulides
Resistance to antibiotics and antimicrobial compounds is a significant problem for human and animal health globally. The development and introduction of new antimicrobial compounds are urgently needed, and copper oxide nanoparticles (CuO NPs) have found widespread application across various sectors including biomedicine, pharmacy, catalysis, cosmetics, and many others. What makes them particularly attractive is the possibility of their synthesis through biogenic routes. In this study, we synthesized biogenic green tea (GT, Camellia sinensis )-derived CuO NPs (GT CuO NPs) and examined their biophysical properties, in vitro toxicity for mammalian cells in culture, and then tested them against Neisseria gonorrhoeae , an exemplar Gram-negative bacterium from the World Health Organization's Priority Pathogen List...
April 17, 2024: ACS Applied Materials & Interfaces