Arvin Arani, Matthew C Murphy, Huzefa Bhopalwala, Shivaram P Arunachalam, Phillip J Rossman, Joshua D Trzasko, Kevin Glaser, Yi Sui, Tina Gunderson, Adelaide M Arruda-Olson, Armando Manduca, Kejal Kantarci, Richard L Ehman, Philip A Araoz
Purpose To investigate the feasibility of using quantitative MR elastography (MRE) to characterize the influence of aging and sex on left ventricular (LV) shear stiffness. Materials and Methods In this prospective study, LV myocardial shear stiffness was measured in 109 healthy volunteers (age range: 18-84 years; mean age, 40 years ± 18 [SD]; 57 women, 52 men) enrolled between November 2018 and September 2019, using a 5-minute MRE acquisition added to a clinical MRI protocol. Linear regression models were used to estimate the association of cardiac MRI and MRE characteristics with age and sex; models were also fit to assess potential age-sex interaction...
June 2024: Radiology. Cardiothoracic imaging