Thang S Han, Leen Antonio, György Bartfai, Terence W O'Neill, Margus Punab, Giulia Rastrelli, Mario Maggi, Jolanta Słowikowska-Hilczer, Jos Tournoy, Dirk Vanderschueren, Michael E J Lean, Ilpo T Huhtaniemi, Frederick C W Wu, Ana I Castro, Marcos C Carreira, Felipe F Casanueva
Empirical evidence for a low normal or reference interval for serum prolactin (PRL) is lacking for men, while the implications of very low PRL levels for human health have never been studied. A clinical state of "PRL deficiency" has not been defined except in relation to lactation. Using data from the European Male Ageing Study (EMAS), we analyzed the distribution of PRL in 3,369 community-dwelling European men, aged 40-80 years at phase-1 and free from acute illnesses. In total, 2,948 and 2,644 PRL samples were collected during phase-1 and phase-2 (3 to 5...
June 3, 2024: Reviews in Endocrine & Metabolic Disorders