keyword
https://read.qxmd.com/read/38731859/dolutegravir-and-folic-acid-interaction-during-neural-system-development-in-zebrafish-embryos
#41
JOURNAL ARTICLE
Daniela Zizioli, Eugenia Quiros-Roldan, Sara Ferretti, Luca Mignani, Giorgio Tiecco, Eugenio Monti, Francesco Castelli, Isabella Zanella
Dolutegravir (DTG) is one of the most prescribed antiretroviral drugs for treating people with HIV infection, including women of child-bearing potential or pregnant. Nonetheless, neuropsychiatric symptoms are frequently reported. Early reports suggested that, probably in relation to folic acid (FA) shortage, DTG may induce neural tube defects in infants born to women taking the drug during pregnancy. Subsequent reports did not definitively confirm these findings. Recent studies in animal models have highlighted the association between DTG exposure in utero and congenital anomalies, and an increased risk of neurologic abnormalities in children exposed during in utero life has been reported...
April 24, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38730563/the-social-aspects-of-illness-children-s-and-parents-explanations-of-the-relation-between-social-categories-and-illness-in-a-predominantly-white-u-s-sample
#42
JOURNAL ARTICLE
David Menendez, Danielle Labotka, Valerie A Umscheid, Susan A Gelman
The COVID-19 pandemic in the United States has had a disproportionate impact on Black, low-income, and elderly individuals. We recruited 175 predominantly white children ages 5-12 and their parents (N = 112) and asked which of two individuals (differing in age, gender, race, social class, or personality) was more likely to get sick with either COVID-19 or the common cold and why. Children and parents reported that older adults were more likely to get sick than younger adults, but reported few differences based on gender, race, social class, or personality...
May 10, 2024: Child Development
https://read.qxmd.com/read/38730502/exploring-the-changing-association-between-parental-and-adolescent-fruit-and-vegetable-intakes-from-age-10-to-30%C3%A2-years
#43
JOURNAL ARTICLE
Tanya Braune, Jean Adams, Eleanor M Winpenny
BACKGROUND: Adolescence is a pivotal developmental stage, where escalating rates of overweight and obesity have raised concerns about diet quality and its association with adverse health outcomes. Parents are known to have considerable influence on childhood diet, but how this influence changes as adolescents mature is unknown. This study investigates the association between parental fruit and vegetable (FV) intake and adolescent FV consumption, exploring how this changes across adolescence and when adolescents leave home...
May 10, 2024: International Journal of Behavioral Nutrition and Physical Activity
https://read.qxmd.com/read/38730438/comparison-of-dmft-and-behavior-rating-scores-between-children-with-systemic-disease-and-healthy-children-at-the-first-dental-visit
#44
COMPARATIVE STUDY
Gizem Erbas Unverdi, Beste Ozgur, Hamdi Cem Gungor, Paul S Casamassimo
PURPOSE: To evaluate and compare oral health and behavior scores at the first dental visit and dental treatment need using general anesthesia/sedation (GA/S) of children with systemic diseases (SD) and healthy children. METHODS: Data were obtained from healthy children (n = 87) and children with SD (n = 79), aged 4 to 6 years, presenting to a hospital dental clinic for a first dental examination. The total number of decayed, missing and filled teeth (dmft), dental behavior score using Frankl Scale, and dental treatment need using GA/S were recorded...
May 10, 2024: BMC Oral Health
https://read.qxmd.com/read/38730407/evaluation-of-a-walking-school-bus-program-a-cluster-randomized-controlled-trial
#45
RANDOMIZED CONTROLLED TRIAL
Ashleigh M Johnson, Chuan Zhou, Miriam Haviland, Jason A Mendoza
BACKGROUND: The purpose of this study was to investigate the effects of a walking school bus intervention on children's active commuting to school. METHODS: We conducted a randomized controlled trial (RCT) in Houston, Texas (Year 1) and Seattle, Washington (Years 2-4) from 2012 to 2016. The study had a two-arm, cluster randomized design comparing the intervention (walking school bus and education materials) to the control (education materials) over one school year October/November - May/June)...
May 10, 2024: International Journal of Behavioral Nutrition and Physical Activity
https://read.qxmd.com/read/38730350/clinical-genetic-and-cognitive-correlates-of-seizure-occurrences-in-phelan-mcdermid-syndrome
#46
JOURNAL ARTICLE
Tess Levy, Jacob Gluckman, Paige M Siper, Danielle Halpern, Jessica Zweifach, Rajna Filip-Dhima, J Lloyd Holder, M Pilar Trelles, Kristina Johnson, Jonathan A Bernstein, Elizabeth Berry-Kravis, Craig M Powell, Latha Valluripalli Soorya, Audrey Thurm, Joseph D Buxbaum, Mustafa Sahin, Alexander Kolevzon, Siddharth Srivastava
BACKGROUND: Phelan-McDermid syndrome (PMS) is a genetic neurodevelopmental disorder caused by SHANK3 haploinsufficiency and is associated with an increased risk for seizures. Previous literature indicates that around one third of individuals with PMS also have epilepsy or seizures, with a wide range of types and ages of onset. Investigating the impact of seizures on intellectual and adaptive functioning for PMS is a primary concern for caregivers and is important to understanding the natural history of this syndrome...
May 10, 2024: Journal of Neurodevelopmental Disorders
https://read.qxmd.com/read/38729603/transdiagnostic-sleep-and-circadian-intervention-in-youth-long-term-follow-up-of-a-randomized-controlled-trial
#47
JOURNAL ARTICLE
Eli S Susman, Estephania Ovalle Patino, Sondra S Tiab, Lu Dong, Nicole B Gumport, Laurel D Sarfan, Stephen P Hinshaw, Allison G Harvey
OBJECTIVE: This preregistered study compared the effects of the Transdiagnostic Sleep and Circadian Intervention (TranS-C) to Psychoeducation about sleep, health, yoga, meditation, and outdoor appreciation activities (PE) on sleep and circadian functioning, health risk, and sleep-health behaviors, at long-term follow-up (LTFU), an average of 8 years following treatment. We also examined if more sleep-health behaviors at LTFU were associated with better sleep and circadian functioning at LTFU and if better sleep and circadian functioning were associated with lower health risk at LTFU...
May 6, 2024: Journal of the American Academy of Child and Adolescent Psychiatry
https://read.qxmd.com/read/38729060/children-s-animistic-beliefs-toward-a-humanoid-robot-and-other-objects
#48
JOURNAL ARTICLE
Kosuke Taniguchi, Mako Okanda
This study examined children's beliefs about a humanoid robot by examining their behavioral and verbal responses. We investigated whether 3- and 5-year-old children would treat the humanoid robot gently along with other objects and tools with and without a face and whether 3- and 5-year-olds would attribute moral, perceptual, and psychological properties to these targets. Although 3-year-olds did not treat objects gently or rudely, they were likely to affirm that hitting targets was acceptable despite targets having psychological and perceptual properties...
May 9, 2024: Journal of Experimental Child Psychology
https://read.qxmd.com/read/38728264/the-milk-study-protocol-a-longitudinal-prospective-cohort-study-of-the-relationship-between-human-milk-metabolic-hormone-concentration-maternal-body-composition-and-early-growth-and-satiety-development-in-samoan-infants-aged-1-4-months
#49
JOURNAL ARTICLE
Victoria Harries, Jyothi Abraham, Lupesina Vesi, Aniva Reupena, Kima Faaselele-Savusa, Rachel L Duckham, Richard Bribiescas, Nicola Hawley
BACKGROUND: Current research suggests that energy transfer through human milk influences infant nutritional development and initiates metabolic programming, influencing eating patterns into adulthood. To date, this research has predominantly been conducted among women in high income settings and/or among undernourished women. We will investigate the relationship between maternal body composition, metabolic hormones in human milk, and infant satiety to explore mechanisms of developmental satiety programming and implications for early infant growth and body composition in Samoans; a population at high risk and prevalence for overweight and obesity...
2024: PloS One
https://read.qxmd.com/read/38728075/a-digital-cognitive-physical-intervention-for-attention-deficit-hyperactivity-disorder-randomized-controlled-trial
#50
RANDOMIZED CONTROLLED TRIAL
Licong Zhao, Heather Agazzi, Yasong Du, Hongdao Meng, Renya Maku, Ke Li, Peter Aspinall, Cynthia Wilson Garvan, Shuanfeng Fang
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders among children. Pharmacotherapy has been the primary treatment for ADHD, supplemented by behavioral interventions. Digital and exercise interventions are promising nonpharmacologic approaches for enhancing the physical and psychological health of children with ADHD. However, the combined impact of digital and exercise therapies remains unclear. OBJECTIVE: The aim of this study was to determine whether BrainFit, a novel digital intervention combining gamified cognitive and exercise training, is efficacious in reducing ADHD symptoms and executive function (EF) among school-aged children with ADHD...
May 10, 2024: Journal of Medical Internet Research
https://read.qxmd.com/read/38728029/chronic-health-conditions-and-longitudinal-employment-in-survivors-of-childhood-cancer
#51
JOURNAL ARTICLE
Neel S Bhatt, Pamela Goodman, Wendy M Leisenring, Gregory T Armstrong, Eric J Chow, Melissa M Hudson, Kevin R Krull, Paul C Nathan, Kevin C Oeffinger, Leslie L Robison, Anne C Kirchhoff, Daniel A Mulrooney
IMPORTANCE: Employment is an important factor in quality of life and provides social and economic support. Longitudinal data on employment and associations with chronic health conditions for adult survivors of childhood cancer are lacking. OBJECTIVE: To evaluate longitudinal trends in employment among survivors of childhood cancer. DESIGN, SETTING, AND PARTICIPANTS: Retrospective cohort study of 5-year cancer survivors diagnosed at age 20 years or younger between 1970 and 1986 enrolled in the multi-institutional Childhood Cancer Survivor Study (CCSS)...
May 1, 2024: JAMA Network Open
https://read.qxmd.com/read/38728003/deliberate-and-self-conscious-adaptation-of-eye-contact-by-autistic-adults
#52
JOURNAL ARTICLE
Alison Garvey, Christian Ryan, Mike Murphy
Eye gaze is widely recognised as an important element in managing social interactions, receiving information from others and communicating information about ourselves. Atypical eye gaze is one of the characteristic hallmarks of autism. Experimental research has contributed significantly to our knowledge of eye-gaze in autism, however, there is a lack of research exploring how autistic individuals describe and understand the phenomenological experience of eye-gaze and eye-contact. The current study explores the subjective experience of deliberate and self-conscious adaptation of eye-contact by autistic adults...
May 10, 2024: Journal of Autism and Developmental Disorders
https://read.qxmd.com/read/38727440/exploring-the-threefold-viewpoint-on-children-s-oral-health-in-a-cross-sectional-study
#53
JOURNAL ARTICLE
Anca-Cristina Perpelea, Ruxandra Sfeatcu, Mihail Tușaliu, Mihaela Tănase, Marina Meleșcanu Imre, Alexandra Ripszky Totan, Cristian Funieru, Dragoș Nicolae Nicolescu, Silviu-Mirel Pițuru
Oral health is situated within the framework of the global health agenda, addressing facets pertaining to well-being and quality of life. The research is based on the need to address variables at the community level to improve schoolchildren's oral health and promote healthy behaviors and aims to carry out an in-depth analysis from the perspective of the factors that influence children's oral health. Step 1, designed by the World Health Organization, was utilized. An easy-to-use web interface was created for data collection...
April 24, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38726908/eeg-functional-connectivity-as-a-riemannian-mediator-an-application-to-malnutrition-and-cognition
#54
JOURNAL ARTICLE
Carlos Lopez Naranjo, Fuleah Abdul Razzaq, Min Li, Ying Wang, Jorge F Bosch-Bayard, Martin A Lindquist, Anisleidy Gonzalez Mitjans, Ronaldo Garcia, Arielle G Rabinowitz, Simon G Anderson, Giuseppe A Chiarenza, Ana Calzada-Reyes, Trinidad Virues-Alba, Janina R Galler, Ludovico Minati, Maria L Bringas Vega, Pedro A Valdes-Sosa
Mediation analysis assesses whether an exposure directly produces changes in cognitive behavior or is influenced by intermediate "mediators". Electroencephalographic (EEG) spectral measurements have been previously used as effective mediators representing diverse aspects of brain function. However, it has been necessary to collapse EEG measures onto a single scalar using standard mediation methods. In this article, we overcome this limitation and examine EEG frequency-resolved functional connectivity measures as a mediator using the full EEG cross-spectral tensor (CST)...
May 2024: Human Brain Mapping
https://read.qxmd.com/read/38726835/do-caring-teachers-protect-african-american-youth-with-adverse-adolescent-experiences-from-risky-behaviors
#55
JOURNAL ARTICLE
Jun Sung Hong, Dong Ha Kim, Hilde Colpin, Vicente J Llorent, Dexter R Voisin, Shantalea Johns
The current study aims to fill the existing research gaps by investigating the role of teacher care in protecting African American adolescents in under-resourced neighborhoods from negative outcomes of adverse life events. The study included 638 adolescents from four under-resourced neighborhoods in Chicago's Southside who were assessed to determine the moderating role of caring teachers on the relationship between adverse adolescent experiences and risky sexual behaviors, substance use, bullying perpetration, and violent behaviors...
May 10, 2024: Clinical Child Psychology and Psychiatry
https://read.qxmd.com/read/38726593/emotion-regulation-and-organizational-skills-in-children-with-adhd-symptoms-are-associated-with-behavioral-parent-training-adherence
#56
JOURNAL ARTICLE
Elizabeth J Hawkey, Aya I Williams, Sara Chung, Elizabeth B Owens, Linda J Pfiffner
OBJECTIVE: Behavioral parent training (BPT) is a well-established treatment for ADHD; however, treatment response is variable. Consistency in parent skill use during BPT is known to influence child outcomes post-treatment, while less research has focused on specific child factors that may be impacting parent skill utilization during treatment. The current study examined associations between child organizational skills and emotion dysregulation (ED) with parent treatment adherence during BPT and post-treatment child impairment...
May 10, 2024: Journal of Attention Disorders
https://read.qxmd.com/read/38726118/mercury-exposure-in-the-norwegian-mother-father-and-child-cohort-study-measured-and-predicted-blood-concentrations-and-associations-with-birth-weight
#57
JOURNAL ARTICLE
Kristine Vejrup, Anne Lise Brantsæter, Ida H Caspersen, Line S Haug, Gro D Villanger, Heidi Aase, Helle K Knutsen
BACKGROUND: Blood total mercury concentration (BTHg) predominantly contains methyl Hg from seafood, and less inorganic Hg. Measured BTHg is often available only in a small proportion of large cohort study samples. Associations between estimated dietary intake of total Hg (THg) and lower birth weight within strata of maternal seafood intake was previously reported in the Norwegian Mother, Father, and Child Cohort Study (MoBa). However, maternal seafood consumption was associated with increased birth weight, indicating negative confounding by seafood in the association between THg intake and birth weight...
May 15, 2024: Heliyon
https://read.qxmd.com/read/38726084/peer-influence-and-its-impact-on-behavior-among-south-indian-adolescents-a-descriptive-cross-sectional-study
#58
JOURNAL ARTICLE
Jisha M Alexander, Renjulal Yesodharan, Malathi G Nayak
BACKGROUND: Peer influence, the development of attitudes, and behavioral changes are some of the phenomenal changes that happen in adolescence. MATERIALS AND METHODS: A descriptive cross-sectional study was undertaken to find out the association between peer influence and behavior among 355 adolescents within the age group of 16 to 18 years, randomly chosen from Pre-university schools of Udupi district, Karnataka using the Peer Influence Scale (PIS) and Strengths and Difficulties Questionnaire (SDQ)...
2024: Journal of Education and Health Promotion
https://read.qxmd.com/read/38726069/determinants-of-health-literacy-and-its-impact-on-glycemic-control-among-women-with-gestational-diabetes-mellitus-in-a-tertiary-care-hospital-puducherry-a-cross-sectional-analytical-study
#59
JOURNAL ARTICLE
Naveen Kumar Veerasetty, J Venkatachalam, Murali Subbaiah, Kalaiselvy Arikrishnan, Bhanushree Soni
BACKGROUND: Health literacy is vital during pregnancy, as maternal health knowledge and behavior have a significant impact on the health of both mother and child. Hence, this study aimed to assess the health literacy status of pregnant women diagnosed with gestational diabetes mellitus (GDM), as well as its associated factors and impact on glycemic control. MATERIALS AND METHODS: The facility-based Cross-sectional analytical study was conducted among 200 pregnant women with GDM in a tertiary care hospital...
2024: Journal of Education and Health Promotion
https://read.qxmd.com/read/38725717/when-a-sibling-has-autism-narrative-review-of-interventions-for-typically-developing-siblings
#60
REVIEW
Karishma Godara, Vaibhav Patil, Nisha Phakey
Being a typically developing sibling to a child with autism spectrum disorder (ASD-Sib) can be associated with several behavioral and mental health problems. With this understanding, researchers are beginning to focus on sibling-oriented interventions. This review seeks to evaluate the current literature on such interventions. We searched digital databases and identified eight relevant studies. The sample (n = 247) had an age range of 4-16 years. The outcomes were generally positive, with improvements in different facets of ASD-Sibs...
March 2024: Indian Journal of Psychological Medicine
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