Evangelos Daskalakis, Boyang Huang, Mohamed H Hassan, Abdalla M Omar, Cian Vyas, Anil A Acar, Ali Fallah, Glen Cooper, Andrew Weightman, Gordon Blunn, Bahattin Koç, Paulo Bartolo
The demand for biomimetic and biocompatible scaffolds in equivalence of structure and material composition for the regeneration of bone tissue is relevantly high. This article is investigating a novel three-dimensional (3D) printed porous structure called bone bricks with a gradient pore size mimicking the structure of the bone tissue. Poly-ɛ-caprolactone (PCL) combined with ceramics such as hydroxyapatite (HA), β-tricalcium phosphate (TCP), and bioglass 45S5 were successfully mixed using a melt blending method and fabricated with the use of screw-assisted extrusion-based additive manufacturing system...
April 1, 2024: 3D Printing and Additive Manufacturing