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REVIEW
August A Longino, Katharine C Martin, Ivor S Douglas
PURPOSE OF REVIEW: Venous pressure is an often-unrecognized cause of patient morbidity. However, bedside assessment of PV is challenging. We review the clinical significance of venous pressure measurement, existing techniques, and introduce the Venous Excess Ultrasound (VExUS) Score as a novel approach using doppler ultrasound to assess venous pressure. RECENT FINDINGS: Studies show clear associations between elevated venous pressure and adverse outcomes in critically ill patients...
June 1, 2024: Current Opinion in Critical Care
#62
REVIEW
Fernando Suarez Sipmann, Juan Antonio Sanchez Giralt, Gerardo Tusman
PURPOSE OF REVIEW: To describe current and near future developments and applications of CO2 kinetics in clinical respiratory and cardiovascular monitoring. RECENT FINDINGS: In the last years, we have witnessed a renewed interest in CO2 kinetics in relation with a better understanding of volumetric capnography and its derived parameters. This together with technological advances and improved measurement systems have expanded the monitoring potential of CO2 kinetics including breath by breath continuous end-expiratory lung volume and continuous noninvasive cardiac output...
June 1, 2024: Current Opinion in Critical Care
#63
REVIEW
Sanjay Subramanian, Jeremy C Pamplin
PURPOSE OF REVIEW: This article summarizes recent developments in the application of telemedicine, specifically tele-critical care (TCC), toward enhancing patient care during various types of emergencies and patient rescue scenarios when there are limited resources in terms of staff expertise (i.e., knowledge, skills, and abilities), staffing numbers, space, and supplies due to patient location (e.g., a non-ICU bed, the emergency department, a rural hospital) or patient volume as in pandemic surges...
June 1, 2024: Current Opinion in Critical Care
#64
EDITORIAL
Heatherlee Bailey
No abstract text is available yet for this article.
June 1, 2024: Current Opinion in Critical Care
#65
JOURNAL ARTICLE
August L Longino, Katharine Martin, Ivor J Douglas
PURPOSE OF REVIEW: Venous pressure is an often-unrecognized cause of patient morbidity. However, bedside assessment of PV is challenging. We review the clinical significance of venous pressure measurement, existing techniques, and introduce the Venous Excess Ultrasound (VExUS) Score as a novel approach using doppler ultrasound to assess venous pressure. RECENT FINDINGS: Studies show clear associations between elevated venous pressure and adverse outcomes in critically ill patients...
March 29, 2024: Current Opinion in Critical Care
#66
JOURNAL ARTICLE
Sanjay Subramanian, Jeremy C Pamplin
PURPOSE OF REVIEW: This article summarizes recent developments in the application of telemedicine, specifically tele-critical care (TCC), toward enhancing patient care during various types of emergencies and patient rescue scenarios when there are limited resources in terms of staff expertise (i.e., knowledge, skills, and abilities), staffing numbers, space, and supplies due to patient location (e.g., a non-ICU bed, the emergency department, a rural hospital) or patient volume as in pandemic surges...
April 15, 2024: Current Opinion in Critical Care
#67
JOURNAL ARTICLE
Fernando Suarez Sipmann, Juan Antonio Sanchez Giralt, Gerardo Tusman
PURPOSE OF REVIEW: To describe current and near future developments and applications of CO2 kinetics in clinical respiratory and cardiovascular monitoring. RECENT FINDINGS: In the last years, we have witnessed a renewed interest in CO2 kinetics in relation with a better understanding of volumetric capnography and its derived parameters. This together with technological advances and improved measurement systems have expanded the monitoring potential of CO2 kinetics including breath by breath continuous end-expiratory lung volume and continuous noninvasive cardiac output...
March 29, 2024: Current Opinion in Critical Care
#68
JOURNAL ARTICLE
Jeremy P Gygi, Cole Maguire, Ravi K Patel, Pramod Shinde, Anna Konstorum, Casey P Shannon, Leqi Xu, Annmarie Hoch, Naresh Doni Jayavelu, Elias K Haddad, Elaine F Reed, Monica Kraft, Grace A McComsey, Jordan P Metcalf, Al Ozonoff, Denise Esserman, Charles B Cairns, Nadine Rouphael, Steven E Bosinger, Seunghee Kim-Schulze, Florian Krammer, Lindsey B Rosen, Harm van Bakel, Michael Wilson, Walter L Eckalbar, Holden T Maecker, Charles R Langelier, Hanno Steen, Matthew C Altman, Ruth R Montgomery, Ofer Levy, Esther Melamed, Bali Pulendran, Joann Diray-Arce, Kinga K Smolen, Gabriela K Fragiadakis, Patrice M Becker, Rafick P Sekaly, Lauren Ir Ehrlich, Slim Fourati, Bjoern Peters, Steven H Kleinstein, Leying Guan
BACKGROUNDPatients hospitalized for COVID-19 exhibit diverse clinical outcomes, with outcomes for some individuals diverging over time even though their initial disease severity appears similar to that of other patients. A systematic evaluation of molecular and cellular profiles over the full disease course can link immune programs and their coordination with progression heterogeneity.METHODSWe performed deep immunophenotyping and conducted longitudinal multiomics modeling, integrating 10 assays for 1,152 Immunophenotyping Assessment in a COVID-19 Cohort (IMPACC) study participants and identifying several immune cascades that were significant drivers of differential clinical outcomes...
May 1, 2024: Journal of Clinical Investigation
#69
COMPARATIVE STUDY
Mojtaba Hedayati-Ch, Hadi Sedigh Ebrahim-Saraie, Arash Bakhshi
INTRODUCTION: Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which appeared in 2019, has been classified as critical and non-critical according to clinical signs and symptoms. Critical patients require mechanical ventilation and intensive care unit (ICU) admission, whereas non-critical patients require neither mechanical ventilation nor ICU admission. Several factors have been recently identified as effective factors, including blood cell count, enzymes, blood markers, and underlying diseases...
2024: Frontiers in Immunology
#70
JOURNAL ARTICLE
Tipwarin Phongmekhin, Ray Wang
No abstract text is available yet for this article.
March 2024: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
#71
JOURNAL ARTICLE
Philip Emerson, Arthas Flabouris, Josephine Thomas, Jeremy Fernando, Siva Senthuran, Serena Knowles, Naomi Hammond, Krish Sundararajan
OBJECTIVE: We aimed to describe the characteristics, outcomes and resource utilisation of patients being cared for in an ICU after undergoing elective surgery in Australia and New Zealand (ANZ). METHODS: This was a point prevalence study involving 51 adult ICUs in ANZ in June 2021. Patients met inclusion criteria if they were being treated in a participating ICU on he study dates. Patients were categorised according to whether they had undergone elective surgery, admitted directly from theatre or unplanned from the ward...
March 2024: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
#72
JOURNAL ARTICLE
Meghan C Gray, Chani Traube, Taylor B Sewell, Andrew S Geneslaw
OBJECTIVE: Delirium is an under-recognized problem in critically ill children. Although delirium is common in adults hospitalized with COVID-19, the relationship between pediatric COVID-19 and delirium has not been described. To address this gap, we characterized delirium in critically ill children with different manifestations of COVID-19 and investigated associations among demographic, disease, and treatment factors. We hypothesized that multisystem inflammatory syndrome in children (MIS-C) would be associated with a higher incidence of delirium given its underlying pathophysiology of hyperinflammation...
April 30, 2024: Journal of Intensive Care Medicine
#73
JOURNAL ARTICLE
Huw R Woodbridge, Christopher J McCarthy, Mandy Jones, Matthew Willis, David B Antcliffe, Caroline M Alexander, Anthony C Gordon
BACKGROUND: Physical rehabilitation of critically ill patients is implemented to improve physical outcomes from an intensive care stay. However, before rehabilitation is implemented, a risk assessment is essential, based on robust safety data. To develop this information, a uniform definition of relevant adverse events is required. The assessment of cardiovascular stability is particularly relevant before physical activity as there is uncertainty over when it is safe to start rehabilitation with patients receiving vasoactive drugs...
April 30, 2024: Critical Care: the Official Journal of the Critical Care Forum
#74
RANDOMIZED CONTROLLED TRIAL
Eliisa Nissilä, Marja Hynninen, Ville Jalkanen, Anne Kuitunen, Minna Bäcklund, Outi Inkinen, Johanna Hästbacka
BACKGROUND: Screening for hazardous alcohol use and performing brief interventions (BIs) are recommended to reduce alcohol-related negative health consequences. We aimed to compare the effectiveness (defined as an at least 10% absolute difference) of BI with usual care in reducing alcohol intake in intensive care unit survivors with history of hazardous alcohol use. METHODS: We used Alcohol Use Disorder Identification Test-Consumption (AUDIT-C) score to assess history of alcohol use...
April 30, 2024: Critical Care: the Official Journal of the Critical Care Forum
#75
JOURNAL ARTICLE
J A Sanchez Giralt, G Tusman, M Wallin, M Hallback, A Perez Lucendo, M Sanchez Galindo, B Abad Santamaria, E Paz Calzada, P Garcia Garcia, D Rodriguez Huerta, A Canabal Berlanga, Fernando Suarez-Sipmann
RATIONALE: End-expiratory lung volume (EELV) is reduced in mechanically ventilated patients, especially in pathologic conditions. The resulting heterogeneous distribution of ventilation increases the risk for ventilation induced lung injury. Clinical measurement of EELV however, remains difficult. OBJECTIVE: Validation of a novel continuous capnodynamic method based on expired carbon dioxide (CO2 ) kinetics for measuring EELV in mechanically ventilated critically-ill patients...
April 30, 2024: Critical Care: the Official Journal of the Critical Care Forum
#76
JOURNAL ARTICLE
Sarina A Fazio, Irene Cortés-Puch, Jacqueline C Stocking, Amy L Doroy, Hugh Black, Anna Liu, Sandra L Taylor, Jason Y Adams
BACKGROUND: Early mobility interventions in intensive care units (ICUs) are safe and improve outcomes in subsets of critically ill adults. However, implementation varies, and the optimal mobility dose remains unclear. OBJECTIVE: To test for associations between daily dose of out-of-bed mobility and patient outcomes in different ICUs. METHODS: In this retrospective cohort study of electronic records from 7 adult ICUs in an academic quarternary hospital, multivariable linear regression was used to examine the effects of out-of-bed events per mobility-eligible day on mechanical ventilation duration and length of ICU and hospital stays...
May 1, 2024: American Journal of Critical Care
#77
JOURNAL ARTICLE
Amanda C Moale, Erica M Motter, Peter Eisenhauer, Nimit Gandhi, S Peter Kim, Tim D Girard, Charles F Reynolds, Natalie E Leland, Judy C Chang, Leslie P Scheunemann
BACKGROUND: To date, no intervention has definitively improved outcomes for families of critical illness survivors. An integrated perspective on caregivers' needs after critical illness could help identify high-priority intervention targets and improve outcomes. OBJECTIVES: To obtain diverse perspectives on the needs, barriers and facilitators, and social determinants of health associated with family caregiving across the critical illness continuum and assess the extent to which successful caregiving interventions in other populations may be adapted to the critical illness context...
May 1, 2024: American Journal of Critical Care
#78
JOURNAL ARTICLE
Rebecca L Rich, Jennifer M Montero, Kyle E Dillon, Patrick Condon, Mathew Vadaparampil
BACKGROUND: Sepsis alerts commonly used for intensive care unit (ICU) patients can lead to alert fatigue because these patients generally meet 1 or more of the criteria for systemic inflammatory response syndrome. To identify ICU patients at greatest risk for sepsis-related consequences, an ICU-specific sepsis alert was implemented. OBJECTIVE: To evaluate an ICU sepsis alert based on modified criteria for systemic inflammatory response syndrome among critically ill medical patients...
May 1, 2024: American Journal of Critical Care
#79
JOURNAL ARTICLE
Anna Robinson, Michelle A Mathiason, Carol Manchester, Mary Fran Tracy
BACKGROUND: Intensive care unit (ICU) patients experience hypoglycemia at nearly 4 times the rate seen in non-ICU counterparts. Although inpatient hypoglycemia management relies on nurse-driven protocols, protocol adherence varies between institutions and units. OBJECTIVE: To compare hypoglycemia management between ICU and non-ICU patients in an institution with high adherence to a hypoglycemia protocol. METHODS: This secondary analysis used retrospective medical record data...
May 1, 2024: American Journal of Critical Care
#80
JOURNAL ARTICLE
Somnath Bose, Danielle Groat, Joanna L Stollings, Patrick Barney, Victor D Dinglas, Valerie M Goodspeed, Harris Carmichael, Mustafa Mir-Kasimov, James C Jackson, Dale M Needham, Samuel M Brown, Carla M Sevin
BACKGROUND: Among survivors of critical illness, prescription of potentially inappropriate medications (PIM) at hospital discharge is thought to be an important, modifiable patient safety concern. To date, there are little empirical data evaluating this issue. RESEARCH QUESTION: The objective of this study was to determine the frequency of PIM prescribed to survivors of acute respiratory failure (ARF) at hospital discharge and explore their association with readmissions or death within 90 days of hospital discharge...
April 29, 2024: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
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