Ting Cheng, Jia-Lin Hou, Zi-Yi Han, Xing-Lei Geng, Yao-Chen Zhang, Ke-Yi Fan, Liu Liu, He-Yi Zhang, Yue-Hong Huo, Xiao-Feng Li, Sheng-Xiao Zhang
BACKGROUND: Observational evidence suggests that type 1 diabetes mellitus (T1DM) is associated with the risk of osteoporosis (OP). Nevertheless, it is not apparent whether these correlations indicate a causal relationship. To elucidate the causal relationship, a two-sample Mendelian randomization (MR) analysis was performed. METHODS: T1DM data was obtained from the large genome-wide association study (GWAS), in which 6683 cases and 12,173 controls from 12 European cohorts were involved...
April 16, 2024: Experimental Gerontology