keyword
Keywords estimated glomerular filtratio...

estimated glomerular filtration rate

https://read.qxmd.com/read/38690898/risk-of-recurrent-stroke-and-dementia-following-acute-stroke-by-changes-in-kidney-function-results-from-the-perindopril-protection-against-recurrent-stroke-study
#41
JOURNAL ARTICLE
Toshiki Maeda, Mark Woodward, Min Jun, Yuki Sakamoto, Xiaoying Chen, Kunihiro Matsushita, Guiseppe Mancia, Hisatomi Arima, Craig S Anderson, John Chalmers, Katie Harris
BACKGROUND: Limited data exist on the relationship between declining kidney function and cardiovascular events, dementia, and mortality in patients with a history of stroke.Thus the aims of the study were to investigate functional relationships between dynamic kidney function change and cardiovascular outcomes, and clarify whether adding kidney parameters to conventional cardiovascular risk factors improves model discrimination. METHODS: Post hoc analysis of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS) clinical trial of blood pressure lowering for the secondary prevention of stroke...
March 11, 2024: Journal of Hypertension
https://read.qxmd.com/read/38690711/switching-from-tenofovir-disoproxil-fumarate-to-tenofovir-alafenamide-in-virologically-suppressed-patient-with-chronic-hepatitis-b
#42
JOURNAL ARTICLE
Heechul Nam, Ji Won Han, Soon Kyu Lee, Hyun Yang, Hae Lim Lee, Pil Soo Sung, Myeong Jun Song, Jung Hyun Kwon, Jeong Won Jang, U-Im Chang, Chang Wook Kim, Soon Woo Nam, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Jin Mo Yang, Hee Yeon Kim
BACKGROUND AND AIM: Our study evaluated the outcomes of switching from tenofovir disoproxil fumarate (TDF) to tenofovir alafenamide (TAF) in patients with chronic hepatitis B (CHB). We assessed viral and biochemical responses as well as changes in the estimated glomerular filtration rate (eGFR) and bone mineral density (BMD). METHODS: This retrospective multicenter study included CHB patients who achieved virologic response (VR) (HBV DNA < 20 IU/mL) while on TDF and were subsequently switched to TAF between April 2018 and October 2021...
May 1, 2024: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/38690617/risk-factors-for-pneumocystis-jirovecii-pneumonia-after-kidney-transplantation-a-systematic-review-and-meta-analysis
#43
REVIEW
Bingjie Cheng, Chang Qi, Senlin Zhang, Xiaowen Wang
BACKGROUND AND OBJECTIVE: Pneumocystis jirovecii pneumonia (PJP), an opportunistic infection, often leads to an increase in hospitalization time and mortality rates in kidney transplant (KT) recipients. However, the risk factors associated with PJP in KT recipients remain debatable. Therefore, we conducted this meta-analysis to identify risk factors for PJP, which could potentially help to reduce PJP incidence and improve outcome of KT recipients. METHODS: We systematically retrieved relevant studies in PubMed, EMBASE, and the Cochrane Library up to November 2023...
May 2024: Clinical Transplantation
https://read.qxmd.com/read/38689836/the-10-year-effects-of-intensive-lifestyle-intervention-on-kidney-outcomes
#44
JOURNAL ARTICLE
Linda-Marie U Lavenburg, Douglas E Schaubel, Ariana M Chao, Peter P Reese, Jordana B Cohen
RATIONALE & OBJECTIVE: Limited data exist on longitudinal kidney outcomes after nonsurgical obesity treatments. We investigated the effects of intensive lifestyle intervention on kidney function over 10 years. STUDY DESIGN: Post hoc analysis of Action for Health in Diabetes (Look AHEAD) randomized controlled trial. SETTING & PARTICIPANTS: We studied 4,901 individuals with type 2 diabetes and body mass index of ≥25 kg/m2 enrolled in Look AHEAD (2001-2015)...
May 2024: Kidney medicine
https://read.qxmd.com/read/38689835/pain-and-health-related-quality-of-life-in-autosomal-dominant-polycystic-kidney-disease-results-from-a-national-patient-powered-registry
#45
JOURNAL ARTICLE
Elise Hoover, Vanessa Holliday, Nicole Merullo, Dorothee Oberdhan, Ronald D Perrone, Chris Rusconi, Meyeon Park, Milind A Phadnis, Nadeesha Thewarapperuma, Neera K Dahl
RATIONALE & OBJECTIVE: Autosomal dominant polycystic kidney disease (ADPKD) affects health-related quality of life (HRQoL) including pain, discomfort, fatigue, emotional distress, and impaired mobility. Stakeholders prioritized kidney cyst-related pain as an important core outcome domain in clinical trials, leading to the development of disease-specific assessment tools. STUDY DESIGN: The ADPKD Registry is hosted online with multiple disease-specific patient-reported outcomes modules to characterize the patient experience in the United States...
May 2024: Kidney medicine
https://read.qxmd.com/read/38689834/external-validation-of-the-kidney-failure-risk-equation-among-urban-community-based-chinese-patients-with-ckd
#46
JOURNAL ARTICLE
Ling Pan, Jinwei Wang, Yang Deng, Yexiang Sun, Zhenyu Nie, Xiaoyu Sun, Chao Yang, Guohui Ding, Ming-Hui Zhao, Yunhua Liao, Luxia Zhang
RATIONALE & OBJECTIVE: The Kidney Failure Risk Equations have been proven to perform well in multinational databases, whereas validation in Asian populations is lacking. This study sought to externally validate the equations in a community-based chronic kidney disease cohort in China. STUDY DESIGN: A retrospective cohort study. SETTING & PARTICIPANTS: Patients with and estimated glomerular filtration rate (eGFR) < 60 mL/min/1...
May 2024: Kidney medicine
https://read.qxmd.com/read/38689511/the-association-between-blood-pressure-variability-and-renal-damage-in-patients-with-primary-aldosteronism
#47
JOURNAL ARTICLE
Siying Wu, Sen Li, Jing Huang, Jie Yu, Chaoping Wei, Lixia Wei, Shuangbei Zhu, Shanshan Chen, Meilan Chen, Jianling Li
This research examines the association between blood pressure variability (BPV) and renal damage in a cohort of 129 primary aldosteronism (PA) patients, employing ambulatory blood pressure monitoring (ABPM) for comparative analysis with individuals diagnosed with essential hypertension (EH). The study reveals that PA patients exhibited significantly elevated levels of cystatin C and urine microalbumin/creatinine ratio (UACR). Additionally, a higher prevalence of non-dipping blood pressure patterns in PA patients suggests an increased risk of circadian blood pressure regulation disturbances...
April 30, 2024: Journal of Clinical Hypertension
https://read.qxmd.com/read/38688809/efficacy-and-safety-of-yiqi-peiyuan-granules-for-improving-the-short-term-prognosis-of-patients-with-acute-kidney-injury-a-multicenter-double-blind-placebo-controlled-randomized-trial
#48
JOURNAL ARTICLE
Jia-Jia Wu, Tian-Yi Zhang, Ying-Hui Qi, Min-Yan Zhu, Yan Fang, Chao-Jun Qi, Li-Ou Cao, Ji-Fang Lu, Bo-Han Lu, Lu-Min Tang, Jian-Xiao Shen, Shan Mou
BACKGROUND: Yiqi Peiyuan (YQPY) prescription, a composite prescription of traditional Chinese medicine, has been used to prevent or delay the continued deterioration of renal function after acute kidney injury (AKI) in some institutions and has shown considerable efficacy. OBJECTIVE: This is the first randomized controlled trial to assess efficacy and safety of YQPY for improving short-term prognosis in adult patients with AKI. DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS: This is a prospective, double-blind, multicenter, randomized, and placebo-controlled clinical trial...
April 23, 2024: Journal of Integrative Medicine
https://read.qxmd.com/read/38686902/initial-egfr-changes-with-sglt2-inhibitor-in-patients-with-type-2-diabetes-and-associations-with-the-risk-of-abnormal-serum-potassium-level
#49
JOURNAL ARTICLE
Yi-Wei Kao, Tze-Fan Chao, Shao-Wei Chen, Yu-Wen Cheng, Yi-Hsin Chan, Pao-Hsien Chu
BACKGROUND: Both high and low levels of serum potassium measurements are linked with a higher risk of adverse clinical events among patients with type 2 diabetes. The study was aimed at evaluating the implications of the various degrees of initial estimated glomerular filtration rate (eGFR) change on subsequent serum potassium homeostasis following sodium-glucose cotransporter-2 inhibitor (SGLT2i) initiation among patients with type 2 diabetes. METHODS AND RESULTS: We used medical data from a multicenter health care provider in Taiwan and recruited 5529 patients with type 2 diabetes with baseline/follow-up eGFR data available after 4 to 12 weeks of SGLT2i treatment from June 1, 2016, to December 31, 2018...
April 30, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38685954/association-between-dietary-inflammation-index-and-albuminuria-results-from-the-national-health-and-nutrition-examination-survey
#50
JOURNAL ARTICLE
Ling Ding, Haipeng Guo, Chao Zhang, Bo Jiang, Shuo Zhang, Jian Zhang
BACKGROUND: The Dietary Inflammation Index (DII) is a tool for evaluating the potential for dietary inflammation, and inflammation is a major cause of exacerbation in chronic kidney disease. Our study aimed to investigate the relationship between DII and albuminuria. METHODS: Data were obtained from the 2005-2018 National Health and Nutrition Examination Survey (NHANES) after excluding pregnant, minors, and missing data of urinary albumin-creatinine ratio (ACR), estimated glomerular filtration rate (eGFR), and DII were enrolled in our study...
2024: Frontiers in Nutrition
https://read.qxmd.com/read/38685603/prognostic-impact-of-heart-failure-admission-in-survivors-of-acute-myocardial-infarction
#51
JOURNAL ARTICLE
Satoshi Takeuchi, Satoshi Honda, Kensaku Nishihira, Sunao Kojima, Misa Takegami, Yasuhide Asaumi, Mike Saji, Jun Yamashita, Kiyoshi Hibi, Jun Takahashi, Yasuhiko Sakata, Morimasa Takayama, Tetsuya Sumiyoshi, Hisao Ogawa, Kazuo Kimura, Satoshi Yasuda
AIMS: The incidence and prognosis of symptomatic heart failure following acute myocardial infarction (AMI) in the primary percutaneous coronary intervention era have rarely been reported in the literature. This study aimed to (i) determine the incidence of heart failure admission among AMI survivors, (ii) compare 1 year outcomes between patients with heart failure admission and those without, and (iii) identify the independent risk factors associated with heart failure admission...
April 29, 2024: ESC Heart Failure
https://read.qxmd.com/read/38685197/favorable-outcome-after-single-kidney-transplantation-from-small-donors-in-children-a-match-controlled-certain-registry-study
#52
JOURNAL ARTICLE
Raphael Schild, Karla Carvajal Abreu, Anja Büscher, Nele Kanzelmeyer, Susanne Lezius, Kai Krupka, Marcus Weitz, Agnieszka Prytula, Nikoleta Printza, László Berta, Seha Kamil Saygılı, Anne-Laure Sellier-Leclerc, Giuseppina Spartà, Stephen D Marks, Markus J Kemper, Sabine König, Rezan Topaloglu, Dominik Müller, Günter Klaus, Stefanie Weber, Jun Oh, Uta Herden, Andrea Carraro, Luca Dello Strologo, Gema Ariceta, Peter Hoyer, Burkhard Tönshoff, Lars Pape
BACKGROUND: Kidney transplantation (KTx) from small donors is associated with inferior graft survival in registry studies, whereas single-center studies show favorable results. METHODS: We compared 175 pediatric KTx from small donors ≤20 kg (SDKTx) with 170 age-matched recipients from adult donors (ADKTx) from 20 centers within the Cooperative European Paediatric Renal Transplant Initiative registry. Graft survival and estimated glomerular filtration rate (eGFR) were analyzed by Cox regression and mixed models...
April 30, 2024: Transplantation
https://read.qxmd.com/read/38685196/antecedent-cardiac-arrest-status-of-donation-after-circulatory-determination-of-death-dcdd-kidney-donors-and-the-risk-of-delayed-graft-function-after-kidney-transplantation-a-cohort-study
#53
JOURNAL ARTICLE
Adam Philipoff, Yingxin Lin, Armando Teixeira-Pinto, Ryan Gately, Jonathan C Craig, Helen Opdam, Jeremy C Chapman, Henry Pleass, Natasha M Rogers, Christopher E Davies, Stephen McDonald, Jean Yang, Pedro Lopez, Germaine Wong, Wai H Lim
BACKGROUND: The number of donors from donation after circulatory determination of death (DCDD) has increased by at least 4-fold over the past decade. This study evaluated the association between the antecedent cardiac arrest status of controlled DCDD donors and the risk of delayed graft function (DGF). METHODS: Using data from the Australia and New Zealand Dialysis and Transplant, the associations between antecedent cardiac arrest status of DCDD donors before withdrawal of cardiorespiratory support, DGF, posttransplant estimated glomerular filtration rate (eGFR), and allograft loss were examined using adjusted logistic, linear mixed modeling, and cox regression, respectively...
April 30, 2024: Transplantation
https://read.qxmd.com/read/38684099/sodium-glucose-cotransporter-2-inhibitors-and-the-risk-for-dialysis-and-cardiovascular-disease-in-patients-with-stage-5-chronic-kidney-disease
#54
JOURNAL ARTICLE
Fu-Shun Yen, Chii-Min Hwu, Jia-Sin Liu, Yi-Ling Wu, Keong Chong, Chih-Cheng Hsu
BACKGROUND: No studies have reported the long-term outcomes of initiating sodium-glucose cotransporter-2 inhibitors (SGLT2is) in patients with estimated glomerular filtration rates less than 20 mL/min/1.73 m2 to predialysis. OBJECTIVE: To compare the risk for dialysis, cardiovascular events, and death between SGLT2i users and nonusers in patients with type 2 diabetes (T2D) and stage 5 chronic kidney disease (CKD). DESIGN: Target trial emulation study...
April 30, 2024: Annals of Internal Medicine
https://read.qxmd.com/read/38681898/reasons-efficacy-and-safety-of-switching-to-dolutegravir-based-regimens-among-virologically-suppressed-plwh-a-retrospective-cohort-study-of-96-weeks
#55
JOURNAL ARTICLE
Meiju Deng, Na Chen, Xiaojie Lao, Xiaolei Wang, Jiantao Fu, Lulu Xing, Hongxin Zhao
PURPOSE: The study aimed to explore the reasons, efficacy, and safety of switching to dolutegravir (DTG) based regimens in virologically suppressed people living with HIV (PLWH) in tertiary hospitals in China. Therefore, the study could provide a valuable reference for the rational clinical use of DTG. METHODS: PLWH's basic information, treatment details, and reasons for switching were collected, through the electrical clinical medical record system and telephone follow-up...
2024: Infection and Drug Resistance
https://read.qxmd.com/read/38680581/changes-in-renal-function-and-morphological-variations-of-kidney-diseases-in-rheumatoid-arthritis-patients
#56
JOURNAL ARTICLE
Yan Tang, Yuliya Varavko, Raisa Aringazina, Irina Menshikova
OBJECTIVE: Rheumatoid nephropathy is one of the most severe extra-articular manifestations of rheumatoid arthritis (RA) associated with a very unfavorable prognosis. This study aimed to identify changes in renal function and morphological variations of kidney diseases in RA patients. METHODS: The study enrolled patients (126 patients) between 18 and 55 years of age with a confirmed active RA of more than 12 months. Each patient underwent the following range of laboratory and instrumental research methods: general clinical analysis of blood and urine, performing urinalysis according to Nechiporenko method; determining daily proteinuria; determining the blood content of glucose, urea, creatinine, uric acid, total bilirubin, liver transaminase level, ionogram, lipidogram, and coagulogram; determining the blood content of rheumatoid factor, anti-streptolysin O, and C-reactive protein; and X-ray of the joints of hands and feet...
April 2024: Asian Journal of Urology
https://read.qxmd.com/read/38680116/empagliflozin-in-type-2-diabetes-with-and-without-ckd-and-non-diabetic-ckd-protocol-for-3-randomized-double-blind-placebo-controlled-cross-over-trials
#57
JOURNAL ARTICLE
Steffen Flindt Nielsen, Camilla Lundgreen Duus, Niels Henrik Buus, Jesper Nørgaard Bech, Frank Holden Mose
BACKGROUND: Sodium-Glucose-Cotransporter 2 inhibitors (SGLT2i) have revolutionized treatment of type 2 diabetes mellitus (DM2) and chronic kidney disease (CKD), reducing risk of cardiovascular and renal endpoints by up to 40%. The underlying mechanisms are not fully understood. OBJECTIVE: To examine the effects of empagliflozin versus placebo on renal hemodynamics, sodium balance, vascular function, and markers of the innate immune system in patients with DM2, DM2 and CKD and non-diabetic CKD...
April 25, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38680053/real-world-effectiveness-of-sodium-glucose-cotransporter-2-inhibitors-on-the-progression-of-chronic-kidney-disease-in-patients-without-diabetes-with-and-without-albuminuria
#58
JOURNAL ARTICLE
Afif Nakhleh, Muhammad Abdul-Ghani, Sivan Gazit, Adi Gross, Idit Livnat, Maya Greenbloom, Adva Yarden, Khaled Khazim, Naim Shehadeh, Cheli Melzer Cohen
AIM: To examine the renal effects of sodium-glucose cotransporter-2 (SGLT2) inhibition among non-diabetic individuals with chronic kidney disease (CKD) in a real-world setting. METHODS: We collected de-identified data on adults without diabetes and with an estimated glomerular filtration rate (eGFR) of 25-60 mL/min/1.73 m2 , who initiated the SGLT2 inhibitors dapagliflozin or empagliflozin between September 2020 and November 2022 at Maccabi Healthcare Services, an Israeli health maintenance organization...
April 28, 2024: Diabetes, Obesity & Metabolism
https://read.qxmd.com/read/38679665/chronic-kidney-disease-and-risk-of-bloodstream-infections-and-sepsis-a-17-year-follow-up-of-the-population-based-tr%C3%A3-ndelag-health-study-in-norway
#59
JOURNAL ARTICLE
Kristin Vardheim Liyanarachi, Randi Marie Mohus, Tormod Rogne, Lise Tuset Gustad, Bjørn Olav Åsvold, Solfrid Romundstad, Erik Solligård, Stein Hallan, Jan Kristian Damås
PURPOSE: Bloodstream infections (BSI) and sepsis are important causes of hospitalization, loss of health, and death globally. Targetable risk factors need to be identified to improve prevention and treatment. In this study, we aimed to evaluate the association of chronic kidney disease (CKD) and risk of and mortality from BSI and sepsis in the general population during a 22-year period. METHODS: We conducted a prospective cohort study among participants in the population-based Norwegian HUNT Study, where 68,438 participated...
April 29, 2024: Infection
https://read.qxmd.com/read/38679212/dose-effect-relationship-of-kidney-function-after-stereotactic-ablative-body-radiotherapy-for-primary-renal-cell-carcinoma-trog-15-03-fastrack-ii
#60
JOURNAL ARTICLE
Mathieu Gaudreault, Nicholas Hardcastle, Price Jackson, Lachlan McIntosh, Braden Higgs, David Pryor, Mark Sidhom, Rachael Dykyj, Alisha Moore, Tomas Kron, Shankar Siva
BACKGROUND: Stereotactic ablative body radiotherapy (SABR) is a novel option to treat primary renal cell carcinoma (RCC). However, a high radiation dose may be received by the treated kidney, which may affect its function post-treatment. This study investigates the dose-effect relationship of kidney SABR with posttreatment renal function. METHODS: This was a prespecified secondary endpoint of the multicenter FASTRACK II clinical trial (NCT02613819). Patients received either 26 Gy in a single fraction (SF) for tumors with a maximal diameter of 4 cm or less, or 42 Gy in three fractions (multi-fraction (MF)) for larger tumors...
April 26, 2024: International Journal of Radiation Oncology, Biology, Physics
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