Priyadarshi Prajjwal, Mohammed Dheyaa Marsool Marsool, Vikas Yadav, Ramya S D Kanagala, Yeruva Bheemeswara Reddy, Jobby John, Justin Riley Lam, Nanditha Karra, Bita Amiri, Moiz Ul Islam, Venkatesh Nithya, Ali Dheyaa Marsool Marsool, Srikanth Gadam, Neel Vora, Omniat Amir Hussin
BACKGROUND: Scleroderma, also referred to as systemic sclerosis, is a multifaceted autoimmune condition characterized by abnormal fibrosis and impaired vascular function. Pathologically, it encompasses the persistent presence of inflammation, abnormal collagen buildup, and restructuring of blood vessels in various organs, resulting in a wide range of clinical symptoms. This review incorporates the most recent scientific literature on scleroderma, with a particular emphasis on its pathophysiology, clinical manifestations, diagnostic approaches, and treatment options...
April 2024: Health Science Reports