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Brain Gym

Maell Cullen, Ben Davey, Karl J Friston, Rosalyn J Moran
BACKGROUND: Artificial intelligence has recently attained humanlike performance in a number of gamelike domains. These advances have been spurred by brain-inspired architectures and algorithms such as hierarchical filtering and reinforcement learning. OpenAI Gym is an open-source platform in which to train, test, and benchmark algorithms-it provides a range of tasks, including those of classic arcade games such as Doom. Here we describe how the platform might be used as a simulation, test, and diagnostic paradigm for psychiatric conditions...
September 2018: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
Felix R Day, Ken K Ong, John R B Perry
The negative impacts of social isolation and loneliness on health are well documented. However, little is known about their possible biological determinants. In up to 452,302 UK Biobank study participants, we perform genome-wide association study analyses for loneliness and regular participation in social activities. We identify 15 genomic loci (P < 5 × 10-8 ) for loneliness, and demonstrate a likely causal association between adiposity and increased susceptibility to loneliness and depressive symptoms...
July 3, 2018: Nature Communications
Frédérique Poncet, Pascale Pradat-Diehl, Marie-Eve Lamontagne, Anne Alifax, Pascaline Fradelizi, Maude Barette, Bonnie Swaine
BACKGROUND: A holistic, intensive and interdisciplinary rehabilitation program for people with acquired brain injury (ABI) was developed at the Pitié-Salpêtrière Hospital, France (5 days/week for 7 weeks). This program, recently demonstrated effective, aimed to optimize the ability of people with ABI to perform activities and improve their participation by using individual and group interventions involving ecologically valid activities inside (e.g., in the gym and kitchen) and outside the hospital...
September 2017: Annals of Physical and Rehabilitation Medicine
Tao Zhang, Chung-Chih Lin, Tsang-Chu Yu, Jing Sun, Wen-Chuin Hsu, Alice May-Kuen Wong
The aim of this study is to design and develop a fun cube (FC) based brain gym (BG) cognitive function assessment system using the wireless sensor network and multimedia technologies. The system comprised (1) interaction devices, FCs and a workstation used as interactive tools for collecting and transferring data to the server, (2) a BG information management system responsible for managing the cognitive games and storing test results, and (3) a feedback system used for conducting the analysis of cognitive functions to assist caregivers in screening high risk groups with mild cognitive impairment...
May 1, 2017: Computers in Biology and Medicine
Kyo-Man Koo, Chun-Jong Kim, Chae-Hee Park, Jung-Kyun Byeun, Geon-Woo Seo
Older adults with disability might have been increasing due to the rapid aging of society. Many studies showed that physical activity is an essential part for improving quality of life in later lives. Regular physical activity is an efficient means that has roles of primary prevention and secondary prevention. However, there were few studies regarding older adults with disability and physical activity participation. The purpose of this current study was to investigate restriction factors to regularly participate older adults with disability in physical activity by employing keyword network analysis...
August 2016: Journal of Exercise Rehabilitation
Perry Else
While "outside of society" for much of the last sixty years, adolescents have attracted attention in recent times because of perceptions of their anti-social and, in some cases, violent behaviour. Teenagers face many challenges on their journey to adulthood; growth spurts, hormone developments and changes in the structure of the brain. These biological challenges have been affected since around 1990 by the impact of technology and the subsequent cultural changes. Activities, like the technology-driven, socially-networked pastime, Neknomination, amongst others, meet basic drives that gym-based activities do not...
2014: Children
Tabitha A Cheng, Jeneita M Bell, Tadesse Haileyesus, Julie Gilchrist, David E Sugerman, Victor G Coronado
OBJECTIVE: To describe the circumstances, characteristics, and trends of emergency department (ED) visits for nonfatal, playground-related traumatic brain injury (TBI) among persons aged ≤14 years. METHODS: The National Electronic Injury Surveillance System-All Injury Program from January 1, 2001, through December 31, 2013, was examined. US Census bridged-race population estimates were used as the denominator to compute rates per 100 000 population. SAS and Joinpoint linear weighted regression analyses were used to analyze the best-fitting join-point and the annual modeled rate change...
June 2016: Pediatrics
Giuseppina Sgandurra, Laura Bartalena, Francesca Cecchi, Giovanni Cioni, Matteo Giampietri, Gorm Greisen, Anna Herskind, Emanuela Inguaggiato, Jakob Lorentzen, Jens Bo Nielsen, Martina Orlando, Paolo Dario
BACKGROUND: CareToy is an intelligent system, inspired by baby gyms, aimed to provide an intensive, individualized, home-based and family-centred early intervention (EI) program. AIMS: A pilot study was carried out to explore the feasibility of CareToy intervention in preterm infants, aged 3-9 months of corrected age. METHODS: Twenty low-risk preterm infants, without brain lesion or other clinical complications (14 allocated to CareToy intervention and 6 to Standard Care) were recruited...
June 2016: Research in Developmental Disabilities
Tara Rezapour, Javad Hatami, Ali Farhoudian, Mehmet Sofuoglu, Alireza Noroozi, Reza Daneshmand, Ahmadreza Samiei, Hamed Ekhtiari
Despite extensive evidence for cognitive deficits associated with drug use and multiple publications supporting the efficacy of cognitive rehabilitation treatment (CRT) services for drug addictions, there are a few well-structured tools and organized programs to improve cognitive abilities in substance users. Most published studies on cognitive rehabilitation for drug dependent patients used rehabilitation tools, which have been previously designed for other types of brain injuries such as schizophrenia or traumatic brain injuries and not specifically designed for drug dependent patients...
October 2015: Basic and Clinical Neuroscience
Ulrike Morgenstern, Kerstin Ketelhut, Diana Rösler
BACKGROUND: Dementia is characterized by reduced memory and concentration abilities leading to a decrease in activities of daily living. Various studies have shown that various forms of physical exercise have a positive therapeutic effect at an early stage of dementia. OBJECTIVE: In the present study the effects of an exercise-based Brain-Gym concept on the concentration and routine daily competences were evaluated in dementia patients. MATERIAL AND METHODS: During a 4-month intervention period specially trained nursing staff and healthcare students put this exercise program into practice...
January 2017: Zeitschrift Für Gerontologie und Geriatrie
Liu Zhuang, Shi Shenxun, Liu Xingdang, Zhao Menglong, Liu Congjin, Wang Yuankai, Liu Miao
OBJECTIVE: To assess the perfusion changes in brains of patients with varying levels of generalized anxiety disorder (GAD). METHODS: A total of 38 GAD outpatients of Department of Psychiatry at our hospital from February to August, 2014 and 10 healthy controls received a 99mTC-ECD SPECT/CT scan with scenium analysis. Differences between brain perfusion and anxiety levels were analyzed by SPSS 16. 0 with one-way ANOVA, Pearson's Chi-square, t test and Spearman's correlation...
April 7, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
José M Cancela, Ma Helena Vila Suárez, Jamine Vasconcelos, Ana Lima, Carlos Ayán
This study evaluates the impact of Brain Gym (BG) training in active older adults. Eighty-five participants were assigned to four training groups: BG (n = 18), BG plus water-based exercise (n = 18), land-based exercise (n = 30), and land plus water-based exercise (n = 19). The effects of the programs on the attention and memory functions were assessed by means of the symbol digit modality test. The two-min step and the eight-foot up-and-go tests were used to evaluate their impact on fitness level. No program had a significant influence on the participant's cognitive performance, while different effects on the sample' fitness levels were observed...
October 2015: Journal of Aging and Physical Activity
Jeffrey P Cuthbert, Kristi Staniszewski, Kaitlin Hays, Don Gerber, Audrey Natale, Denise O'Dell
OBJECTIVE: To evaluate the feasibility and safety of utilizing a commercially available virtual reality gaming system as a treatment intervention for balance training. DESIGN: A randomized controlled trial in which assessment and analysis were blinded. SETTING: An inpatient rehabilitation facility. INTERVENTION: Interventions included balance-based physical therapy using a Nintendo Wii, as monitored by a physical therapist, and receipt of one-on-one balance-based physical therapy using standard physical therapy modalities available for use in the therapy gym...
2014: Brain Injury: [BI]
Na Zhang, Qiang Ma, Xue-Wei Chen, Chuan-Xiang Xu, Gai-Hong An, Bo Cui, Xiao-Jun She
OBJECTIVE: To explore the effects of retinol acid (RA) and triiodothyronine (T3) on alleviating the impairment of cognitive function by sleep deprivation (SD). METHODS: Male Wistar rats were divided into 4 groups: control group (C group), sleep deprivation group (SD group), sleep deprivation + RA group (SD + RA group) and sleep deprivation + T3 group (SD + T3 group). Open field test (OFT) was used to observe the nervous behavior of the rats after SD and electrophysiological brain stereotactic method was used to test long-term potentiation (LTP) in dentate gyms (DG) of the rats...
July 2013: Chinese Journal of Applied Physiology
Roger Zemek, Chantalle Clarkin, Ken J Farion, Michael Vassilyadi, Peter Anderson, Brendan Irish, Kristian Goulet, Nick Barrowman, Martin H Osmond
OBJECTIVES: Anxiety modulates symptom perception in adults following concussion, prolonging the time to full recovery. The authors sought to determine whether parental anxiety was associated with persistent postconcussive symptoms (PCS) in their children following concussion. METHODS: A prospective observational cohort with 98 children aged 5 to 17 years following concussion participated from a tertiary pediatric emergency department (ED). The main exposure was parental anxiety at the time of acute presentation following pediatric concussion, measured using the self-administered, validated Spielberger State-Trait Anxiety Inventory-State Anxiety Scale (STAI-S)...
October 2013: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
Samuele Cortese
No abstract text is available yet for this article.
September 2013: Journal of the American Academy of Child and Adolescent Psychiatry
N Kanwisher, R P Woods, M Iacoboni, J C Mazziotta
Positron emission tomography (PET) was used to locate an area in human extrastriate cortex that subserves a specific component process of visual object recognition. Regional blood flow increased in a bilateral extrastriate area on the inferolateral surface of the brain near the border between the occipital and temporal lobes (and a smaller area in the right fusiform gyms) when subjects viewed line drawings of 3-dimensional objects compared to viewing scrambled drawings with no clear shape interpretation. Responses were Seen for both novel and familiar objects, implicating this area in the bottom-up (i...
January 1997: Journal of Cognitive Neuroscience
R Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Lee Walus, Xinhua Lee, Yinghui Hu, Christilyn Graff, Ellen Garber, Werner Meier, Sha Mi
LINGO-1 (leucine-rich repeat and Ig domain containing NOGO receptor interacting protein-1) is a negative regulator of myelination and repair of damaged axons in the central nervous system (CNS). Blocking LINGO-1 function leads to robust remyelination. The anti-LINGO-1 Li81 antibody is currently being evaluated in clinical trials for multiple sclerosis (MS) and is the first MS therapy that directly targets myelin repair. LINGO-1 is selectively expressed in brain and spinal cord but not in peripheral tissues...
November 2011: Journal of Pharmacology and Experimental Therapeutics
Sheila Reid, Jean M Held, Suzanne Lawrence
OBJECTIVE: To assess the intra-/interrater reliability and the validity of the free web-based Shaw Gait Assessment Tool (with visual and numerical output) for assessing speed, cadence, step length, and limb advance time in people with hemiplegic gait. DESIGN: Intra-/interrater reliability and concurrent validity with 2 raters using the Shaw Gait Assessment Tool and 1 rater using a multimemory stopwatch. SETTING: Busy outpatient rehabilitation gym at a tertiary care medical center...
July 2011: Archives of Physical Medicine and Rehabilitation
Goran Spasojević, Zlatan Stojanović, Dusan Susćević, Slobodan Malobabić, Saso Rafajlovski, Vujadin Tatiić
BACKGROUND/AIM: Studies of visible (extrasulcal) surface of the brain hemispheres are not feasible for measurements of the brain size, but are valuable for analysis and quantification of sexual dimorphism and/or asymmetries of the human brain. Morphological and morphometric investigations of the brain may contribute in genetic studies of the human nervous system. The aim of this study was to determine and to quantify sexual dimorphism and the right/left morphological asymmetry of the visible surface of medial frontal gyms (gyrus frontalis medialis - GFM)...
February 2010: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
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