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JOURNAL ARTICLE
Yu Song, Xiao-Yan Yuan, Hai-Yan Cong, Yuan Liu, Peng Liu, Ming-Yi Wang, Zong-Jun Du
A Gram-negative, facultative anaerobic, non-motile and rod-shaped bacterium, designated 10c7w1T , was isolated from a human gastrointestinal tract. Colonies on agar plates were small, circular, smooth and beige. The optimal growth conditions were determined to be 37 °C, pH 7.0-7.5 and 0 % (w/v) NaCl. Comparative analysis of complete 16S rRNA gene sequences revealed that strain 10c7w1T showed the highest sequence similarity of 95.8 % to Ottowia beijingensis MCCC 1A01410T , followed by Ottowia thiooxydans (95...
May 2024: International Journal of Systematic and Evolutionary Microbiology
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JOURNAL ARTICLE
Natalia E Powers-Riggs, Benedikt O Birgisson, Sumana L Raj, Elisa Biasin, Philipp Lenzen, Diana Bregenholt Zederkof, Morten Haubro, Dagrún K V Tveiten, Robert W Hartsock, Tim B van Driel, Kristjan Kunnus, Matthieu Chollet, Joseph S Robinson, Silke Nelson, Ruaridh Forbes, Kristoffer Haldrup, Kasper S Pedersen, Gianluca Levi, Asmus Ougaard Dohn, Hannes Jónsson, Klaus Braagaard Mo Ller, Adi Natan, Martin Meedom Nielsen, Kelly J Gaffney
Dimeric complexes composed of d8 square planar metal centers and rigid bridging ligands provide model systems to understand the interplay between attractive dispersion forces and steric strain in order to assist the development of reliable methods to model metal dimer complexes more broadly. [Ir2 (dimen)4 ]2+ (dimen = para -diisocyanomenthane) presents a unique case study for such phenomena, as distortions of the optimal structure of a ligand with limited conformational flexibility counteract the attractive dispersive forces from the metal and ligand to yield a complex with two ground state deformational isomers...
May 10, 2024: Journal of the American Chemical Society
#23
JOURNAL ARTICLE
Y Feng, C Zhao, T Li, M Wang, B R Serrano, A R Barcenas, L Qu, W Zhao, M Shen
1. The accumulation of excessive fat plays a role in the development of non-alcoholic fatty liver disease (NAFLD) and phytogenic feed additives have the potential to ameliorate this. This study involved the isolation and culture of primary hepatocytes from chicken embryos to establish a model of hepatic steatosis induced by oleic acid/dexamethasone (OA/DEX). Lipid accumulation and cell viability were assessed using Nile Red staining, Oil Red O staining and cell count Kit -8 (CCK8) following treatment with varying concentrations of quercetin (Que)...
May 10, 2024: British Poultry Science
#24
JOURNAL ARTICLE
Sarah O Ludwig, Melissa W Cater, Georgianna Tuuri
PURPOSE: The purpose of the study was to develop and validate a food literacy instrument specific to individuals with type 2 diabetes mellitus (T2DM). METHODS: Twelve T2DM-specific, food literacy-related statements underwent content validity and face validity testing, and exploratory factor analysis (EFA) was conducted (phase 1). The 6 statements remaining after EFA testing were added to an existing food literacy questionnaire called the Eating and Food Literacy Behaviors Questionnaire (EFLBQ)...
May 10, 2024: The science of diabetes self-management and care
#25
JOURNAL ARTICLE
Salma M Khaled, Iman Amro, Menatalla Abdelkader, Dalia Al Bahari, Mahmoud Al Shawwaf, Majid Alabdulla, Ahmed Alhassan, Amal Ali, Sheeren Aly, Asmaa Amin, Wai Tat Chiu, James Currie, Hana El Fakki, Michael B First, Mohammed H O Hassan, Zainab Hijawi, Rumaisa Mohammed, Marwa Nofal, Salma Salman, Nancy A Sampson, Peter W Woodruff, Ronald C Kessler
OBJECTIVES: Lifetime DSM-5 diagnoses generated by the lay-administered Composite International Diagnostic Interview for DSM-5 (CIDI) in the World Mental Health Qatar (WMHQ) study were compared to diagnoses based on blinded clinician-administered reappraisal interviews. METHODS: Telephone follow-up interviews used the non-patient edition of the Structured Clinician Interview for DSM-5 (SCID) oversampling respondents who screened positive for five diagnoses in the CIDI: major depressive episode, mania/hypomania, panic disorder, generalized anxiety disorder, and obsessive-compulsive disorder...
May 2024: International Journal of Methods in Psychiatric Research
#26
JOURNAL ARTICLE
Sebastian C Coleman, Zelekha A Seedat, Daisie O Pakenham, Andrew J Quinn, Matthew J Brookes, Mark W Woolrich, Karen J Mullinger
The post-movement beta rebound has been studied extensively using magnetoencephalography (MEG) and is reliably modulated by various task parameters as well as illness. Our recent study showed that rebounds, which we generalise as "post-task responses" (PTRs), are a ubiquitous phenomenon in the brain, occurring across the cortex in theta, alpha, and beta bands. Currently, it is unknown whether PTRs following working memory are driven by transient bursts, which are moments of short-lived high amplitude activity, similar to those that drive the post-movement beta rebound...
May 2024: Human Brain Mapping
#27
Yvemarie B O Somsen, Sina Porouchani, Ruben W de Winter, Harmen R Zandbergen, Evert K Jansen, Alexander Nap, Hans W M Niessen, Paul Knaapen
A young female patient presenting with a non-ST-segment elevation myocardial infarction underwent invasive coronary angiography, revealing a total occlusion of the right coronary artery. During percutaneous coronary intervention with dual catheter access, a retrograde tip injection and peculiar retrograde wiring unmasked a giant coronary aneurysm, which noninvasive imaging confirmed.
June 5, 2024: JACC. Case reports
#28
JOURNAL ARTICLE
Min Deng, Jianhua Cao, Gregory van der Kroft, David P J van Dijk, Merel R Aberle, Andrej Grgic, Ulf P Neumann, Georg Wiltberger, Benjamin Balluff, Frank G Schaap, Ron M A Heeren, Steven W M Olde Damink, Sander S Rensen
BACKGROUND: Cancer cachexia is a multifactorial metabolic syndrome characterized by systemic inflammation and ongoing skeletal muscle loss resulting in weakness, poor quality of life, and decreased survival. Whereas lipid accumulation in skeletal muscle is associated with cancer cachexia as well as the prognosis of cancer patients, surprisingly little is known about the nature of the lipids that accumulate in the muscle during cachexia, and whether this is related to inflammation. We aimed to identify the types and distributions of intramyocellular lipids in patients with and without cancer cachexia...
May 9, 2024: Journal of Cachexia, Sarcopenia and Muscle
#29
JOURNAL ARTICLE
Dinesh Kumar, Vandana Kumari, Dinesh Kumar
Trillium govanianum is traditionally used to treat innumerable alignments like sexual disorders, cancer, inflammation etc. Mainly rhizomes of T. govanianum have been explored for phytochemical profiling but comprehensive metabolomics of other parts has not been yet deeply investigated. Thus, current study was aimed for organs-specific (roots, rhizomes, rhizomatous buds, stems, leaves, and fruits) phytochemical profiling of T. govanianum via metabolomics approach. Targeted (steroidal saponins and free sugars) and non-targeted metabolomics were performed by UPLC-PDA/ELSD & UHPLC-Q-TOF-IMS...
May 9, 2024: Scientific Reports
#30
MULTICENTER STUDY
Murat Bardakci, Hilal Karakas, Dogan Bayram, Nilufer Avci, Sait Kitapli, Mirac Ozen, Ferit Aslan, Caglar Koseoglu, Ahmet Kadioglu, Ilknur D Onur, Teoman Sakalar, Mahmut Buyuksimsek, Ali Alkan, Yakup Ergun, Ali O Kaya, Burak Bilgin, Bulent Yalcin
While some clinics have adopted abbreviated neoadjuvant treatment for HER2-positive breast cancer, there remains a shortage of comprehensive clinical data to support this practice. This is a retrospective, multicenter study. A total of 142 patients were included in the study who are HER2-positive breast cancer, aged ≤ 65 years, with left ventricular ejection fraction ≥ 50%, received neoadjuvant chemotherapy and underwent surgery at 10 different oncology centers in Türkiye between October 2016 and December 2022...
May 9, 2024: Scientific Reports
#31
JOURNAL ARTICLE
Elizabeth N Paddy, Oluwasola O D Afolabi, M Sohail
Bioaerosols generated during toilet flushing can contribute to the spread of airborne pathogens and cross-contamination in indoor environments. This presents an increased risk of fomite-mediated or aerosol disease transmission. This study systematically investigated the factors contributing to increased bioaerosol exposure following toilet flushing and developed an empirical model for predicting the exposure-relevant bioaerosol concentration. Air in a toilet cubicle was sampled by impaction after seeding with Clostridium difficile spores...
May 9, 2024: Scientific Reports
#32
JOURNAL ARTICLE
Roel Hoek, Pepijn A van Diemen, Pieter G Raijmakers, Roel S Driessen, Yvemarie B O Somsen, Ruben W de Winter, Ruurt A Jukema, Jos W R Twisk, Lourens F H J Robbers, Pim van der Harst, Antti Saraste, Mark Lubberink, Jens Sörensen, Paul Knaapen, Juhani Knuuti, Ibrahim Danad
Currently, cutoffs of quantitative [15 O]H2 O PET to detect fractional flow reserve (FFR)-defined coronary artery disease (CAD) were derived from a single cohort that included patients without prior CAD. However, prior CAD, sex, and age can influence myocardial blood flow (MBF). Therefore, the present study determined the influence of prior CAD, sex, and age on optimal cutoffs of hyperemic MBF (hMBF) and coronary flow reserve (CFR) and evaluated whether cutoff optimization enhanced diagnostic performance of quantitative [15 O]H2 O PET against an FFR reference standard...
May 9, 2024: Journal of Nuclear Medicine
#33
JOURNAL ARTICLE
Eileen O Dareng, Simon G Coetzee, Jonathan P Tyrer, Pei-Chen Peng, Will Rosenow, Stephanie Chen, Brian D Davis, Felipe Segato Dezem, Ji-Heui Seo, Robbin Nameki, Alberto L Reyes, Katja K H Aben, Hoda Anton-Culver, Natalia N Antonenkova, Gerasimos Aravantinos, Elisa V Bandera, Laura E Beane Freeman, Matthias W Beckmann, Alicia Beeghly-Fadiel, Javier Benitez, Marcus Q Bernardini, Line Bjorge, Amanda Black, Natalia V Bogdanova, Kelly L Bolton, James D Brenton, Agnieszka Budzilowska, Ralf Butzow, Hui Cai, Ian Campbell, Rikki Cannioto, Jenny Chang-Claude, Stephen J Chanock, Kexin Chen, Georgia Chenevix-Trench, Yoke-Eng Chiew, Linda S Cook, Anna DeFazio, Joe Dennis, Jennifer A Doherty, Thilo Dörk, Andreas du Bois, Matthias Dürst, Diana M Eccles, Gabrielle Ene, Peter A Fasching, James M Flanagan, Renée T Fortner, Florentia Fostira, Aleksandra Gentry-Maharaj, Graham G Giles, Marc T Goodman, Jacek Gronwald, Christopher A Haiman, Niclas Håkansson, Florian Heitz, Michelle A T Hildebrandt, Estrid Høgdall, Claus K Høgdall, Ruea-Yea Huang, Allan Jensen, Michael E Jones, Daehee Kang, Beth Y Karlan, Anthony N Karnezis, Linda E Kelemen, Catherine J Kennedy, Elza K Khusnutdinova, Lambertus A Kiemeney, Susanne K Kjaer, Jolanta Kupryjanczyk, Marilyne Labrie, Diether Lambrechts, Melissa C Larson, Nhu D Le, Jenny Lester, Lian Li, Jan Lubiński, Michael Lush, Jeffrey R Marks, Keitaro Matsuo, Taymaa May, John R McLaughlin, Iain A McNeish, Usha Menon, Stacey Missmer, Francesmary Modugno, Melissa Moffitt, Alvaro N Monteiro, Kirsten B Moysich, Steven A Narod, Tu Nguyen-Dumont, Kunle Odunsi, Håkan Olsson, N Charlotte Onland-Moret, Sue K Park, Tanja Pejovic, Jennifer B Permuth, Anna Piskorz, Darya Prokofyeva, Marjorie J Riggan, Harvey A Risch, Cristina Rodríguez-Antona, Mary Anne Rossing, Dale P Sandler, V Wendy Setiawan, Kang Shan, Honglin Song, Melissa C Southey, Helen Steed, Rebecca Sutphen, Anthony J Swerdlow, Soo Hwang Teo, Kathryn L Terry, Pamela J Thompson, Liv Cecilie Vestrheim Thomsen, Linda Titus, Britton Trabert, Ruth Travis, Shelley S Tworoger, Ellen Valen, Els Van Nieuwenhuysen, Digna Velez Edwards, Robert A Vierkant, Penelope M Webb, Clarice R Weinberg, Rayna Matsuno Weise, Nicolas Wentzensen, Emily White, Stacey J Winham, Alicja Wolk, Yin-Ling Woo, Anna H Wu, Li Yan, Drakoulis Yannoukakos, Nur Zeinomar, Wei Zheng, Argyrios Ziogas, Andrew Berchuck, Ellen L Goode, David G Huntsman, Celeste L Pearce, Susan J Ramus, Thomas A Sellers, Matthew L Freedman, Kate Lawrenson, Joellen M Schildkraut, Dennis Hazelett, Jasmine T Plummer, Siddhartha Kar, Michelle R Jones, Paul D P Pharoah, Simon A Gayther
To identify credible causal risk variants (CCVs) associated with different histotypes of epithelial ovarian cancer (EOC), we performed genome-wide association analysis for 470,825 genotyped and 10,163,797 imputed SNPs in 25,981 EOC cases and 105,724 controls of European origin. We identified five histotype-specific EOC risk regions (p value <5 × 10-8 ) and confirmed previously reported associations for 27 risk regions. Conditional analyses identified an additional 11 signals independent of the primary signal at six risk regions (p value <10-5 )...
May 7, 2024: American Journal of Human Genetics
#34
JOURNAL ARTICLE
Priya R Jadhav, Priyanka T Kolhe, Vipul S Ghemud, Pandit N Shelke, Shashikant P Patole, Sanjay D Dhole, Shailendra Satish Dahiwale
The tunability of the Transition Metal Dichalcogenide (TMD) properties has gained attention from numerous researchers due to their wide application in various fields including quantum technology. In the present work, WS2 has been deposited on fluorine doped tin oxide (FTO) substrate and its properties have been studied systematically. These samples were irradiated using gamma radiation for various doses, and the effect on structural, morphological, optical and electrical properties has been reported. The crystallinity of the material is observed to be decreased, and the results are well supported by X-ray diffraction, Raman spectroscopy techniques...
May 9, 2024: Nanotechnology
#35
REVIEW
Hussein O Badr, Michel W Barsoum
Metal oxide nanostructures have received an increasing attention owing to their unique chemical and physical properties along with their widespread applications in various fields. In this article, we provide an overview of our recent discovery - christened Hydroxides-Derived Nanostructures, or HDNs - in which we react hydroxide aqueous solutions (mostly tetramethylammonium hydroxide, TMAH) at temperatures < 100 °C and under atmospheric pressure with various metal-containing precursors to scalably prepare novel metal oxide nanostructures...
May 9, 2024: Advanced Materials
#36
JOURNAL ARTICLE
John W Stewart, Elena M Irons, Giovanna Osorio Abanto, Matthias Zeller, Curtis M Zaleski, Daniel P Predecki
Two 2,4,6-tri-methyl-aniline-based trifuloro-methane-sulfonate (tri-fluoro-methane-sulfonate) salts were synthesized and characterized by single-crystal X-ray diffraction. N ,2,4,6-Tetra-methyl-anilinium tri-fluoro-methane-sulfonate, [C10 H14 NH2 + ][CF3 O3 S- ] ( 1 ), was synthesized via methyl-ation of 2,4,6-tri-methyl-aniline. N -Iso-propyl-idene- N ,2,4,6-tetra-methyl-anilinium tri-fluoro-meth-ane-sulfonate, [C13 H20 N+ ][CF3 O3 S- ] ( 2 ), was synthesized in a two-step reaction where the imine, N -iso-propyl-idene-2,4,6-tri-methyl-aniline, was first prepared via a dehydration reaction to form the Schiff base, followed by methyl-ation using methyl tri-fluoro-methane-sulfonate to form the iminium ion...
April 1, 2024: Acta Crystallographica. Section E, Crystallographic Communications
#37
JOURNAL ARTICLE
Fabio Falcioni, Robert W Molt, Yi Jin, Jonathan P Waltho, Sam Hay, Nigel G J Richards, G Michael Blackburn
Arginine phosphorylation plays numerous roles throughout biology. Arginine kinase (AK) catalyzes the delivery of an anionic phosphoryl group (PO3 - ) from ATP to a planar, trigonal nitrogen in a guanidinium cation. Density functional theory (DFT) calculations have yielded a model of the transition state (TS) for the AK-catalyzed reaction. They reveal a network of over 50 hydrogen bonds that delivers unprecedented pyramidalization and out-of-plane polarization of the arginine guanidinium nitrogen (Nη2) and aligns the electron density on Nη2 with the scissile P-O bond, leading to in-line phosphoryl transfer via an associative mechanism...
May 3, 2024: ACS Catalysis
#38
JOURNAL ARTICLE
Robert J Dambrino, Gunther W Wong, Alan R Tang, Jacob Jo, Aaron M Yengo-Kahn, Nathan R Lindquist, Michael H Freeman, David S Haynes, Kareem O Tawfik, Lola B Chambless, Reid C Thompson, Peter J Morone
Introduction The middle fossa craniotomy (MFCs) is commonly utilized for spontaneous cerebrospinal fluid (CSF) leaks, encephaloceles, and superior semicircular canal dehiscence (SSCD). This study compares postoperative outcomes of MFCs with and without LD use. Methods A retrospective cohort study of adults over the age of 18 years presenting for the repair of nonneoplastic CSF leak, encephalocele, or SSCD via MFC from 2009 to 2021 was conducted. The main exposure of interest was the placement of an LD...
June 2024: Journal of Neurological Surgery. Part B, Skull Base
#39
JOURNAL ARTICLE
Anukul Ghimire, Samveg Shah, Utkarsh Chauhan, Kwaifa Salihu Ibrahim, Kailash Jindal, Rumeyza Kazancioglu, Valerie A Luyckx, Jennifer M MacRae, Timothy O Olanrewaju, Robert R Quinn, Pietro Ravani, Nikhil Shah, Stephanie Thompson, Somkanya Tungsanga, Tushar Vachharanjani, Silvia Arruebo, Fergus J Caskey, Sandrine Damster, Jo-Ann Donner, Vivekanand Jha, Adeera Levin, Charu Malik, Masaomi Nangaku, Syed Saad, Marcello Tonelli, Feng Ye, Ikechi G Okpechi, Aminu K Bello, David W Johnson
BACKGROUND: There is a lack of contemporary data describing global variations in vascular access for hemodialysis (HD). We used the third iteration of the International Society of Nephrology Global Kidney Health Atlas (ISN-GKHA) to highlight differences in funding and availability of hemodialysis accesses used for initiating HD across world regions. METHODS: Survey questions were directed at understanding the funding modules for obtaining vascular access and types of accesses used to initiate dialysis...
May 8, 2024: BMC Nephrology
#40
JOURNAL ARTICLE
Michael B Mahon, Alexandra Sack, O Alejandro Aleuy, Carly Barbera, Ethan Brown, Heather Buelow, David J Civitello, Jeremy M Cohen, Luz A de Wit, Meghan Forstchen, Fletcher W Halliday, Patrick Heffernan, Sarah A Knutie, Alexis Korotasz, Joanna G Larson, Samantha L Rumschlag, Emily Selland, Alexander Shepack, Nitin Vincent, Jason R Rohr
Anthropogenic change is contributing to the rise in emerging infectious diseases, which are significantly correlated with socioeconomic, environmental and ecological factors1 . Studies have shown that infectious disease risk is modified by changes to biodiversity2-6 , climate change7-11 , chemical pollution12-14 , landscape transformations15-20 and species introductions21 . However, it remains unclear which global change drivers most increase disease and under what contexts. Here we amassed a dataset from the literature that contains 2,938 observations of infectious disease responses to global change drivers across 1,497 host-parasite combinations, including plant, animal and human hosts...
May 8, 2024: Nature
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