keyword
https://read.qxmd.com/read/38325187/detection-of-moderate-hepatic-steatosis-on-contrast-enhanced-dual-source-dual-energy-ct-role-and-accuracy-of-virtual-non-contrast-ct
#41
JOURNAL ARTICLE
Roberta Catania, Leo Jia, Maryam Haghshomar, Frank H Miller, Amir A Borhani
PURPOSE: To investigate diagnostic accuracy of virtual non contrast (VNC) images, based on dual-source dual-energy CT (dsDECT), for detection of at least moderate steatosis and to define a threshold value to make this diagnosis on VNC. METHODS: This single-institution retrospective study included patients who had multi-phasic protocol dsDECT. Regions of interests were placed in different segments of the liver and spleen on true non-contrast (TNC), VNC, and portal-venous phase (PVP) images...
March 2024: European Journal of Radiology
https://read.qxmd.com/read/38287718/type-2-diabetes-metabolomics-score-and-risk-of-progression-to-type-2-diabetes-among-women-with-a-history-of-gestational-diabetes-mellitus
#42
JOURNAL ARTICLE
Deirdre K Tobias, Rikuta Hamaya, Clary B Clish, Liming Liang, Amy Deik, Courtney Dennis, Kevin Bullock, Cuilin Zhang, Frank B Hu, JoAnn E Manson
BACKGROUND: Several metabolites are individually related to incident type 2 diabetes (T2D) risk. We prospectively evaluated a novel T2D-metabolite pattern with a risk of progression to T2D among high-risk women with a history of gestational diabetes mellitus (GDM). METHODS: The longitudinal Nurses' Health Study II cohort enroled 116,429 women in 1989 and collected blood samples from 1996 to 1999. We profiled plasma metabolites in 175 incident T2D cases and 175 age-matched controls, all with a history of GDM before the blood draw...
January 2024: Diabetes/metabolism Research and Reviews
https://read.qxmd.com/read/38277604/measurement-of-cp-violation-in-b-0-%C3%A2-%C3%AF-%C3%A2-%C3%A2-%C3%A2-k_-s-0-%C3%A2-%C3%AF-%C3%AF-decays
#43
JOURNAL ARTICLE
R Aaij, A S W Abdelmotteleb, C Abellan Beteta, F Abudinén, T Ackernley, B Adeva, M Adinolfi, P Adlarson, H Afsharnia, C Agapopoulou, C A Aidala, Z Ajaltouni, S Akar, K Akiba, P Albicocco, J Albrecht, F Alessio, M Alexander, A Alfonso Albero, Z Aliouche, P Alvarez Cartelle, R Amalric, S Amato, J L Amey, Y Amhis, L An, L Anderlini, M Andersson, A Andreianov, P Andreola, M Andreotti, D Andreou, D Ao, F Archilli, A Artamonov, M Artuso, E Aslanides, M Atzeni, B Audurier, D Bacher, I Bachiller Perea, S Bachmann, M Bachmayer, J J Back, A Bailly-Reyre, P Baladron Rodriguez, V Balagura, W Baldini, J Baptista de Souza Leite, M Barbetti, I R Barbosa, R J Barlow, S Barsuk, W Barter, M Bartolini, F Baryshnikov, J M Basels, G Bassi, B Batsukh, A Battig, A Bay, A Beck, M Becker, F Bedeschi, I B Bediaga, A Beiter, S Belin, V Bellee, K Belous, I Belov, I Belyaev, G Benane, G Bencivenni, E Ben-Haim, A Berezhnoy, R Bernet, S Bernet Andres, D Berninghoff, H C Bernstein, C Bertella, A Bertolin, C Betancourt, F Betti, J Bex, Ia Bezshyiko, J Bhom, L Bian, M S Bieker, N V Biesuz, P Billoir, A Biolchini, M Birch, F C R Bishop, A Bitadze, A Bizzeti, M P Blago, T Blake, F Blanc, J E Blank, S Blusk, D Bobulska, V Bocharnikov, J A Boelhauve, O Boente Garcia, T Boettcher, A Bohare, A Boldyrev, C S Bolognani, R Bolzonella, N Bondar, F Borgato, S Borghi, M Borsato, J T Borsuk, S A Bouchiba, T J V Bowcock, A Boyer, C Bozzi, M J Bradley, S Braun, A Brea Rodriguez, N Breer, J Brodzicka, A Brossa Gonzalo, J Brown, D Brundu, A Buonaura, L Buonincontri, A T Burke, C Burr, A Bursche, A Butkevich, J S Butter, J Buytaert, W Byczynski, S Cadeddu, H Cai, R Calabrese, L Calefice, S Cali, M Calvi, M Calvo Gomez, J Cambon Bouzas, P Campana, D H Campora Perez, A F Campoverde Quezada, S Capelli, L Capriotti, A Carbone, L Carcedo Salgado, R Cardinale, A Cardini, P Carniti, L Carus, A Casais Vidal, R Caspary, G Casse, M Cattaneo, G Cavallero, V Cavallini, S Celani, J Cerasoli, D Cervenkov, A J Chadwick, I Chahrour, M G Chapman, M Charles, Ph Charpentier, C A Chavez Barajas, M Chefdeville, C Chen, S Chen, A Chernov, S Chernyshenko, V Chobanova, S Cholak, M Chrzaszcz, A Chubykin, V Chulikov, P Ciambrone, M F Cicala, X Cid Vidal, G Ciezarek, P Cifra, P E L Clarke, M Clemencic, H V Cliff, J Closier, J L Cobbledick, C Cocha Toapaxi, V Coco, J Cogan, E Cogneras, L Cojocariu, P Collins, T Colombo, A Comerma-Montells, L Congedo, A Contu, N Cooke, I Corredoira, A Correia, G Corti, J J Cottee Meldrum, B Couturier, D C Craik, M Cruz Torres, R Currie, C L Da Silva, S Dadabaev, L Dai, X Dai, E Dall'Occo, J Dalseno, C D'Ambrosio, J Daniel, A Danilina, P d'Argent, A Davidson, J E Davies, A Davis, O De Aguiar Francisco, J de Boer, K De Bruyn, S De Capua, M De Cian, U De Freitas Carneiro Da Graca, E De Lucia, J M De Miranda, L De Paula, M De Serio, D De Simone, P De Simone, F De Vellis, J A de Vries, C T Dean, F Debernardis, D Decamp, V Dedu, L Del Buono, B Delaney, H-P Dembinski, V Denysenko, O Deschamps, F Dettori, B Dey, P Di Nezza, I Diachkov, S Didenko, S Ding, V Dobishuk, A D Docheva, A Dolmatov, C Dong, A M Donohoe, F Dordei, A C Dos Reis, L Douglas, A G Downes, W Duan, P Duda, M W Dudek, L Dufour, V Duk, P Durante, M M Duras, J M Durham, D Dutta, A Dziurda, A Dzyuba, S Easo, E Eckstein, U Egede, A Egorychev, V Egorychev, C Eirea Orro, S Eisenhardt, E Ejopu, S Ek-In, L Eklund, M Elashri, J Ellbracht, S Ely, A Ene, E Epple, S Escher, J Eschle, S Esen, T Evans, F Fabiano, L N Falcao, Y Fan, B Fang, L Fantini, M Faria, K Farmer, S Farry, D Fazzini, L Felkowski, M Feng, M Feo, M Fernandez Gomez, A D Fernez, F Ferrari, L Ferreira Lopes, F Ferreira Rodrigues, S Ferreres Sole, M Ferrillo, M Ferro-Luzzi, S Filippov, R A Fini, M Fiorini, M Firlej, K M Fischer, D S Fitzgerald, C Fitzpatrick, T Fiutowski, F Fleuret, M Fontana, F Fontanelli, L F Foreman, R Forty, D Foulds-Holt, M Franco Sevilla, M Frank, E Franzoso, G Frau, C Frei, D A Friday, L Frontini, J Fu, Q Fuehring, Y Fujii, T Fulghesu, E Gabriel, G Galati, M D Galati, A Gallas Torreira, D Galli, S Gambetta, M Gandelman, P Gandini, H Gao, R Gao, Y Gao, Y Gao, M Garau, L M Garcia Martin, P Garcia Moreno, J García Pardiñas, B Garcia Plana, F A Garcia Rosales, L Garrido, C Gaspar, R E Geertsema, L L Gerken, E Gersabeck, M Gersabeck, T Gershon, L Giambastiani, F I Giasemis, V Gibson, H K Giemza, A L Gilman, M Giovannetti, A Gioventù, P Gironella Gironell, C Giugliano, M A Giza, K Gizdov, E L Gkougkousis, F C Glaser, V V Gligorov, C Göbel, E Golobardes, D Golubkov, A Golutvin, A Gomes, S Gomez Fernandez, F Goncalves Abrantes, M Goncerz, G Gong, J A Gooding, I V Gorelov, C Gotti, J P Grabowski, L A Granado Cardoso, E Graugés, E Graverini, L Grazette, G Graziani, A T Grecu, L M Greeven, N A Grieser, L Grillo, S Gromov, C Gu, M Guarise, M Guittiere, V Guliaeva, P A Günther, A-K Guseinov, E Gushchin, Y Guz, T Gys, T Hadavizadeh, C Hadjivasiliou, G Haefeli, C Haen, J Haimberger, S C Haines, M Hajheidari, T Halewood-Leagas, M M Halvorsen, P M Hamilton, J Hammerich, Q Han, X Han, S Hansmann-Menzemer, L Hao, N Harnew, T Harrison, M Hartmann, C Hasse, M Hatch, J He, K Heijhoff, F Hemmer, C Henderson, R D L Henderson, A M Hennequin, K Hennessy, L Henry, J Herd, J Heuel, A Hicheur, D Hill, M Hilton, S E Hollitt, J Horswill, R Hou, Y Hou, N Howarth, J Hu, J Hu, W Hu, X Hu, W Huang, X Huang, W Hulsbergen, R J Hunter, M Hushchyn, D Hutchcroft, P Ibis, M Idzik, D Ilin, P Ilten, A Inglessi, A Iniukhin, A Ishteev, K Ivshin, R Jacobsson, H Jage, S J Jaimes Elles, S Jakobsen, E Jans, B K Jashal, A Jawahery, V Jevtic, E Jiang, X Jiang, Y Jiang, Y J Jiang, M John, D Johnson, C R Jones, T P Jones, S Joshi, B Jost, N Jurik, I Juszczak, D Kaminaris, S Kandybei, Y Kang, M Karacson, D Karpenkov, M Karpov, A M Kauniskangas, J W Kautz, F Keizer, D M Keller, M Kenzie, T Ketel, B Khanji, A Kharisova, S Kholodenko, G Khreich, T Kirn, V S Kirsebom, O Kitouni, S Klaver, N Kleijne, K Klimaszewski, M R Kmiec, S Koliiev, L Kolk, A Kondybayeva, A Konoplyannikov, P Kopciewicz, R Kopecna, P Koppenburg, M Korolev, I Kostiuk, O Kot, S Kotriakhova, A Kozachuk, P Kravchenko, L Kravchuk, M Kreps, S Kretzschmar, P Krokovny, W Krupa, W Krzemien, J Kubat, S Kubis, W Kucewicz, M Kucharczyk, V Kudryavtsev, E Kulikova, A Kupsc, B K Kutsenko, D Lacarrere, G Lafferty, A Lai, A Lampis, D Lancierini, C Landesa Gomez, J J Lane, R Lane, C Langenbruch, J Langer, O Lantwin, T Latham, F Lazzari, C Lazzeroni, R Le Gac, S H Lee, R Lefèvre, A Leflat, S Legotin, O Leroy, T Lesiak, B Leverington, A Li, H Li, K Li, L Li, P Li, P-R Li, S Li, T Li, T Li, Y Li, Z Li, Z Lian, X Liang, C Lin, T Lin, R Lindner, V Lisovskyi, R Litvinov, G Liu, H Liu, K Liu, Q Liu, S Liu, Y Liu, Y Liu, A Lobo Salvia, A Loi, J Lomba Castro, T Long, I Longstaff, J H Lopes, A Lopez Huertas, S López Soliño, G H Lovell, Y Lu, C Lucarelli, D Lucchesi, S Luchuk, M Lucio Martinez, V Lukashenko, Y Luo, A Lupato, E Luppi, K Lynch, X-R Lyu, R Ma, S Maccolini, F Machefert, F Maciuc, I Mackay, V Macko, L R Madhan Mohan, M M Madurai, A Maevskiy, D Magdalinski, D Maisuzenko, M W Majewski, J J Malczewski, S Malde, B Malecki, A Malinin, T Maltsev, G Manca, G Mancinelli, C Mancuso, R Manera Escalero, D Manuzzi, C A Manzari, D Marangotto, J F Marchand, U Marconi, S Mariani, C Marin Benito, J Marks, A M Marshall, P J Marshall, G Martelli, G Martellotti, L Martinazzoli, M Martinelli, D Martinez Santos, F Martinez Vidal, A Massafferri, M Materok, R Matev, A Mathad, V Matiunin, C Matteuzzi, K R Mattioli, A Mauri, E Maurice, J Mauricio, M Mazurek, M McCann, L Mcconnell, T H McGrath, N T McHugh, A McNab, R McNulty, B Meadows, G Meier, D Melnychuk, M Merk, A Merli, L Meyer Garcia, D Miao, H Miao, M Mikhasenko, D A Milanes, M Milovanovic, M-N Minard, A Minotti, E Minucci, T Miralles, S E Mitchell, B Mitreska, D S Mitzel, A Modak, A Mödden, R A Mohammed, R D Moise, S Mokhnenko, T Mombächer, M Monk, I A Monroy, S Monteil, A Morcillo Gomez, G Morello, M J Morello, M P Morgenthaler, J Moron, A B Morris, A G Morris, R Mountain, H Mu, Z M Mu, E Muhammad, F Muheim, M Mulder, K Müller, F Mũnoz-Rojas, D Murray, R Murta, P Naik, T Nakada, R Nandakumar, T Nanut, I Nasteva, M Needham, N Neri, S Neubert, N Neufeld, P Neustroev, R Newcombe, J Nicolini, D Nicotra, E M Niel, N Nikitin, P Nogga, N S Nolte, C Normand, J Novoa Fernandez, G Nowak, C Nunez, H N Nur, A Oblakowska-Mucha, V Obraztsov, T Oeser, S Okamura, R Oldeman, F Oliva, M Olocco, C J G Onderwater, R H O'Neil, J M Otalora Goicochea, T Ovsiannikova, P Owen, A Oyanguren, O Ozcelik, K O Padeken, B Pagare, P R Pais, T Pajero, A Palano, M Palutan, G Panshin, L Paolucci, A Papanestis, M Pappagallo, L L Pappalardo, C Pappenheimer, C Parkes, B Passalacqua, G Passaleva, A Pastore, M Patel, J Patoc, C Patrignani, C J Pawley, A Pellegrino, M Pepe Altarelli, S Perazzini, D Pereima, A Pereiro Castro, P Perret, A Perro, K Petridis, A Petrolini, S Petrucci, H Pham, A Philippov, L Pica, M Piccini, B Pietrzyk, G Pietrzyk, D Pinci, F Pisani, M Pizzichemi, V Placinta, M Plo Casasus, F Polci, M Poli Lener, A Poluektov, N Polukhina, I Polyakov, E Polycarpo, S Ponce, D Popov, S Poslavskii, K Prasanth, L Promberger, C Prouve, V Pugatch, V Puill, G Punzi, H R Qi, W Qian, N Qin, S Qu, R Quagliani, B Rachwal, J H Rademacker, R Rajagopalan, M Rama, M Ramírez García, M Ramos Pernas, M S Rangel, F Ratnikov, G Raven, M Rebollo De Miguel, F Redi, J Reich, F Reiss, Z Ren, P K Resmi, R Ribatti, G R Ricart, S Ricciardi, K Richardson, M Richardson-Slipper, K Rinnert, P Robbe, G Robertson, E Rodrigues, E Rodriguez Fernandez, J A Rodriguez Lopez, E Rodriguez Rodriguez, A Rogovskiy, D L Rolf, A Rollings, P Roloff, V Romanovskiy, M Romero Lamas, A Romero Vidal, F Ronchetti, M Rotondo, M S Rudolph, T Ruf, R A Ruiz Fernandez, J Ruiz Vidal, A Ryzhikov, J Ryzka, J J Saborido Silva, N Sagidova, N Sahoo, B Saitta, M Salomoni, C Sanchez Gras, I Sanderswood, R Santacesaria, C Santamarina Rios, M Santimaria, L Santoro, E Santovetti, D Saranin, G Sarpis, M Sarpis, A Sarti, C Satriano, A Satta, M Saur, D Savrina, H Sazak, L G Scantlebury Smead, A Scarabotto, S Schael, S Scherl, A M Schertz, M Schiller, H Schindler, M Schmelling, B Schmidt, S Schmitt, O Schneider, A Schopper, M Schubiger, N Schulte, S Schulte, M H Schune, R Schwemmer, G Schwering, B Sciascia, A Sciuccati, S Sellam, A Semennikov, M Senghi Soares, A Sergi, N Serra, L Sestini, A Seuthe, Y Shang, D M Shangase, M Shapkin, I Shchemerov, L Shchutska, T Shears, L Shekhtman, Z Shen, S Sheng, V Shevchenko, B Shi, E B Shields, Y Shimizu, E Shmanin, R Shorkin, J D Shupperd, B G Siddi, R Silva Coutinho, G Simi, S Simone, M Singla, N Skidmore, R Skuza, T Skwarnicki, M W Slater, J C Smallwood, J G Smeaton, E Smith, K Smith, M Smith, A Snoch, L Soares Lavra, M D Sokoloff, F J P Soler, A Solomin, A Solovev, I Solovyev, R Song, Y Song, Y Song, Y S Song, F L Souza De Almeida, B Souza De Paula, E Spadaro Norella, E Spedicato, J G Speer, E Spiridenkov, P Spradlin, V Sriskaran, F Stagni, M Stahl, S Stahl, S Stanislaus, E N Stein, O Steinkamp, O Stenyakin, H Stevens, D Strekalina, Y Su, F Suljik, J Sun, L Sun, Y Sun, P N Swallow, K Swientek, F Swystun, A Szabelski, T Szumlak, M Szymanski, Y Tan, S Taneja, M D Tat, A Terentev, F Teubert, E Thomas, D J D Thompson, H Tilquin, V Tisserand, S T'Jampens, M Tobin, L Tomassetti, G Tonani, X Tong, D Torres Machado, L Toscano, D Y Tou, C Trippl, G Tuci, N Tuning, A Ukleja, D J Unverzagt, E Ursov, A Usachov, A Ustyuzhanin, U Uwer, V Vagnoni, A Valassi, G Valenti, N Valls Canudas, M Van Dijk, H Van Hecke, E van Herwijnen, C B Van Hulse, R Van Laak, M van Veghel, R Vazquez Gomez, P Vazquez Regueiro, C Vázquez Sierra, S Vecchi, J J Velthuis, M Veltri, A Venkateswaran, M Vesterinen, D Vieira, M Vieites Diaz, X Vilasis-Cardona, E Vilella Figueras, A Villa, P Vincent, F C Volle, D Vom Bruch, V Vorobyev, N Voropaev, K Vos, C Vrahas, J Walsh, E J Walton, G Wan, C Wang, G Wang, J Wang, J Wang, J Wang, J Wang, M Wang, N W Wang, R Wang, X Wang, Y Wang, Z Wang, Z Wang, Z Wang, J A Ward, N K Watson, D Websdale, Y Wei, B D C Westhenry, D J White, M Whitehead, A R Wiederhold, D Wiedner, G Wilkinson, M K Wilkinson, I Williams, M Williams, M R J Williams, R Williams, F F Wilson, W Wislicki, M Witek, L Witola, C P Wong, G Wormser, S A Wotton, H Wu, J Wu, Y Wu, K Wyllie, S Xian, Z Xiang, Y Xie, A Xu, J Xu, L Xu, L Xu, M Xu, Z Xu, Z Xu, Z Xu, D Yang, S Yang, X Yang, Y Yang, Z Yang, Z Yang, V Yeroshenko, H Yeung, H Yin, C Y Yu, J Yu, X Yuan, E Zaffaroni, M Zavertyaev, M Zdybal, M Zeng, C Zhang, D Zhang, J Zhang, L Zhang, S Zhang, S Zhang, Y Zhang, Y Zhang, Y Zhao, A Zharkova, A Zhelezov, Y Zheng, T Zhou, X Zhou, Y Zhou, V Zhovkovska, L Z Zhu, X Zhu, X Zhu, Z Zhu, V Zhukov, J Zhuo, Q Zou, S Zucchelli, D Zuliani, G Zunica
A measurement of time-dependent CP violation in the decays of B^{0} and B[over ¯]^{0} mesons to the final states J/ψ(→μ^{+}μ^{-})K_{S}^{0}, ψ(2S)(→μ^{+}μ^{-})K_{S}^{0} and J/ψ(→e^{+}e^{-})K_{S}^{0} with K_{S}^{0}→π^{+}π^{-} is presented. The data correspond to an integrated luminosity of 6  fb^{-1} collected at a center-of-mass energy of sqrt[s]=13  TeV with the LHCb detector. The CP-violation parameters are measured to be S_{ψK_{S}^{0}}=0...
January 12, 2024: Physical Review Letters
https://read.qxmd.com/read/38272832/kinetics-controlled-perovskite-crystallization-for-high-performance-solar-cells
#44
JOURNAL ARTICLE
Jinghao Ge, Ran Chen, Yabin Ma, Yunfan Wang, Yingjie Hu, Lu Zhang, Fengzhu Li, Xiaokang Ma, Sai-Wing Tsang, Jiaxue You, Alex K Y Jen, Shengzhong Frank Liu
The power conversion efficiencies (PCEs) of perovskite solar cells have recently developed rapidly compared to crystalline silicon solar cells. To have an effective way to control the crystallization of perovskite thin films is the key for achieving good device performance. However, a paradox in perovskite crystallization is from the mismatch between nucleation and Oswald ripening. Usually, the large numbers of nucleation sites tend to weak Oswald ripening. Here, we proposed a new mechanism to promote the formation of nucleation sites by reducing surface energy from 44...
January 25, 2024: Angewandte Chemie
https://read.qxmd.com/read/38272606/association-of-glycaemic-index-and-glycaemic-load-with-type-2-diabetes-cardiovascular-disease-cancer-and-all-cause-mortality-a-meta-analysis-of-mega-cohorts-of-more-than-100%C3%A2-000-participants
#45
JOURNAL ARTICLE
David J A Jenkins, Walter C Willett, Salim Yusuf, Frank B Hu, Andrea J Glenn, Simin Liu, Andrew Mente, Victoria Miller, Shrikant I Bangdiwala, Hertzel C Gerstein, Sabina Sieri, Pietro Ferrari, Alpa V Patel, Marjorie L McCullough, Loïc Le Marchand, Neal D Freedman, Erikka Loftfield, Rashmi Sinha, Xiao-Ou Shu, Mathilde Touvier, Norie Sawada, Shoichiro Tsugane, Piet A van den Brandt, Kerem Shuval, Tauseef Ahmad Khan, Melanie Paquette, Sandhya Sahye-Pudaruth, Darshna Patel, Teenie Fei Yi Siu, Korbua Srichaikul, Cyril W C Kendall, John L Sievenpiper
BACKGROUND: There is debate over whether the glycaemic index of foods relates to chronic disease. We aimed to assess the associations between glycaemic index (GI) and glycaemic load (GL) and type 2 diabetes, cardiovascular disease, diabetes-related cancers, and all-cause mortality. METHODS: We did a meta-analysis of large cohorts (≥100 000 participants) identified from the Richard Doll Consortium. We searched the Cochrane Library, MEDLINE, PubMed, Embase, Web of Science, and Scopus for cohorts that prospectively examined associations between GI or GL and chronic disease outcomes published from database inception to Aug 4, 2023...
February 2024: Lancet Diabetes & Endocrinology
https://read.qxmd.com/read/38264362/plant-based-diets-and-the-incidence-of-cardiovascular-disease-the-million-veteran-program
#46
JOURNAL ARTICLE
Yanping Li, Dong D Wang, Xuan-Mai T Nguyen, Rebecca J Song, Yuk-Lam Ho, Frank B Hu, Walter C Willett, Peter W F Wilson, Kelly Cho, John Michael Gaziano, Luc Djousse
BACKGROUND: A healthful plant-based diet was associated with lower risks of coronary heart disease and type 2 diabetes, and a favourable profile of adiposity-associated biomarkers, while an unhealthful plant-based diet was associated with elevated risk of cardiometabolic disease in health professional populations. However, little is known about the associations between plant-based dietary patterns and risk of cardiovascular disease (CVD) in US veterans. METHODS: The study population consisted of 148 506 participants who were free of diabetes, CVD and cancer at baseline in the Veterans Affairs (VA) Million Veteran Program...
December 2023: BMJ nutrition, prevention & health
https://read.qxmd.com/read/38245716/plasma-metabolite-profile-of-legume-consumption-and-future-risk-of-type-2-diabetes-and-cardiovascular-disease
#47
JOURNAL ARTICLE
Hernando J Margara-Escudero, Indira Paz-Graniel, Jesús García-Gavilán, Miguel Ruiz-Canela, Qi Sun, Clary B Clish, Estefania Toledo, Dolores Corella, Ramón Estruch, Emilio Ros, Olga Castañer, Fernando Arós, Miquel Fiol, Marta Guasch-Ferré, José Lapetra, Cristina Razquin, Courtney Dennis, Amy Deik, Jun Li, Enrique Gómez-Gracia, Nancy Babio, Miguel A Martínez-González, Frank B Hu, Jordi Salas-Salvadó
BACKGROUND: Legume consumption has been linked to a reduced risk of type 2 diabetes (T2D) and cardiovascular disease (CVD), while the potential association between plasma metabolites associated with legume consumption and the risk of cardiometabolic diseases has never been explored. Therefore, we aimed to identify a metabolite signature of legume consumption, and subsequently investigate its potential association with the incidence of T2D and CVD. METHODS: The current cross-sectional and longitudinal analysis was conducted in 1833 PREDIMED study participants (mean age 67 years, 57...
January 20, 2024: Cardiovascular Diabetology
https://read.qxmd.com/read/38227336/consumption-of-100-fruit-juice-and-body-weight-in-children-and-adults-a-systematic-review-and-meta-analysis
#48
JOURNAL ARTICLE
Michelle Nguyen, Sarah E Jarvis, Laura Chiavaroli, Sonia Blanco Mejia, Andreea Zurbau, Tauseef A Khan, Deirdre K Tobias, Walter C Willett, Frank B Hu, Anthony J Hanley, Catherine S Birken, John L Sievenpiper, Vasanti S Malik
IMPORTANCE: Concerns have been raised that frequent consumption of 100% fruit juice may promote weight gain. Current evidence on fruit juice and weight gain has yielded mixed findings from both observational studies and clinical trials. OBJECTIVE: To synthesize the available evidence on 100% fruit juice consumption and body weight in children and adults. DATA SOURCES: MEDLINE, Embase, and Cochrane databases were searched through May 18, 2023...
March 1, 2024: JAMA Pediatrics
https://read.qxmd.com/read/38223529/a-mechanistic-biomarker-investigation-of-fialuridine-hepatotoxicity-using-the-chimeric-tk-nog-hu-liver-mouse-model-and-in-vitro-micropatterned-hepatocyte-cocultures
#49
JOURNAL ARTICLE
Amy G Aslamkhan, Laura Michna, Alexei Podtelezhnikov, Katerina Vlasakova, Hiroshi Suemizu, Yasuyuki Ohnishi, Liping Liu, Pamela Lane, Qiuwei Xu, Matthew C Kuhls, Zhibin Wang, Stephen Pacchione, Zoltan Erdos, Rodger William Tracy, Kenneth Koeplinger, Nagaraja Muniappa, John Valentine, Alema Galijatovic-Idrizbegovic, Warren E Glaab, Frank D Sistare, Jose Lebron
Fialuridine (FIAU) is a nucleoside-based drug that caused liver failure and deaths in a human clinical trial that were not predicted by nonclinical safety studies. A recent report concluded that a TK-NOG humanized liver (hu-liver) mouse model detected human-specific FIAU liver toxicity, and broader use of that model could improve drug safety testing. We further evaluated this model at similar dose levels to assess FIAU sensitivity and potential mechanistic biomarkers. Although we were unable to reproduce the marked acute liver toxicity with two separate studies (including one with a "sensitized" donor), we identified molecular biomarkers reflecting the early stages of FIAU mitochondrial toxicity, which were not seen with its stereoisomer (FIRU)...
February 2024: Toxicology Research
https://read.qxmd.com/read/38219955/scmr-expert-consensus-statement-for-cardiovascular-magnetic-resonance-of-patients-with-a-cardiac-implantable-electronic-device
#50
JOURNAL ARTICLE
Daniel Kim, Jeremy D Collins, James A White, Kate Hanneman, Daniel C Lee, Amit R Patel, Peng Hu, Harold Litt, Jonathan W Weinsaft, Rachel Davids, Kanae Mukai, Ming-Yen Ng, Julian A Luetkens, Ariel Roguin, Carlos E Rochitte, Pamela K Woodard, Charlotte Manisty, Karolina M Zareba, Lluis Mont, Frank Bogun, Daniel B Ennis, Saman Nazarian, Gregory Webster, Jadranka Stojanovska
Cardiovascular magnetic resonance (CMR) is a proven imaging modality for informing diagnosis and prognosis, guiding therapeutic decisions, and risk stratifying surgical intervention. Patients with a cardiac implantable electronic device (CIED) would be expected to derive particular benefit from CMR given high prevalence of cardiomyopathy and arrhythmia. While several guidelines have been published over the last 16 years, it is important to recognize that both the CIED and CMR technologies, as well as our knowledge in MR safety, have evolved rapidly during that period...
January 12, 2024: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/38199011/-i-don-t-have-a-telephone-to-the-fetus-clinicians-conceptions-of-fetal-patienthood-in-maternal-fetal-surgery-counseling
#51
JOURNAL ARTICLE
E Goldblatt Hyatt, Abigail Wilpers, Mert Ozan Bahtiyar, Yunzhe Hu, Daisy Leon-Martinez, Frank A Chervenak, Judith L M McCoyd
RATIONALE: Maternal fetal surgery (MFS) has developed rapidly since the 1960s and centers for fetal diagnosis and therapy (CFDT) have proliferated. As a result, CFDT clinicians have intervened with fetuses through pregnant bodies for decades, yet the patienthood status of the fetus and its implications for the pregnant person's autonomy have been relatively unexamined. OBJECTIVE: Our overall research aims were threefold: (1) to explore how clinicians train for and provide counseling for MFS; (2) to examine how clinicians assess fetal patienthood and its implications; and (3) to understand clinicians' professed needs and their recommendations for education and training for the provision of MFS counseling...
December 23, 2023: Social Science & Medicine
https://read.qxmd.com/read/38187603/human-induced-pluripotent-stem-cell-based-hepatic-modeling-of-lipid-metabolism-associated-tm6sf2-e167k-variant
#52
Lanuza Ap Faccioli, Yiyue Sun, Takashi Motomura, Zhenghao Liu, Takeshi Kurihara, Zhiping Hu, Zeliha Cetin, Jonathan Franks, Donna Stolz, Alina Ostrowska, Rodrigo M Florentino, Ira J Fox, Alejandro Soto-Gutierrez
BACKGROUND AND AIMS: TM6SF2 rs58542926 (E167K) is associated with an increase in the prevalence of Metabolic Disfunction-Associated Steatotic Liver Disease (MASLD). Despite all the investigation related to the role of this variant in lipid metabolism, conflicting results in mouse studies underscore the importance of creating a human model for understanding the TM6SF2 mechanism. Therefore, the aim of this study is to generate a reliable human in vitro model that mimic the effects of the TM6SF2 E167K mutation and can be used for future mechanism studies...
December 18, 2023: bioRxiv
https://read.qxmd.com/read/38185281/sugar-sweetened-or-artificially-sweetened-beverage-consumption-physical-activity-and-risk-of-cardiovascular-disease-in-adults-a-prospective-cohort-study
#53
JOURNAL ARTICLE
Lorena S Pacheco, Deirdre K Tobias, Yanping Li, Shilpa N Bhupathiraju, Walter C Willett, David S Ludwig, Cara B Ebbeling, Danielle E Haslam, Jean-Philippe Drouin-Chartier, Frank B Hu, Marta Guasch-Ferré
BACKGROUND: Whether physical activity could mitigate the adverse impacts of sugar-sweetened beverages (SSBs) or artificially sweetened beverages (ASBs) on incident cardiovascular disease (CVD) remains uncertain. OBJECTIVES: This study aimed to examine the independent and joint associations between SSB or ASB consumption and physical activity and risk of CVD, defined as fatal and nonfatal coronary artery disease and stroke, in adults from 2 United States-based prospective cohort studies...
January 6, 2024: American Journal of Clinical Nutrition
https://read.qxmd.com/read/38178231/correction-associations-between-plant-based-dietary-patterns-and-risks-of-type-2-diabetes-cardiovascular-disease-cancer-and-mortality-a-systematic-review-and-meta-analysis
#54
Yeli Wang, Binkai Liu, Han Han, Yang Hu, Lu Zhu, Eric B Rimm, Frank B Hu, Qi Sun
No abstract text is available yet for this article.
January 4, 2024: Nutrition Journal
https://read.qxmd.com/read/38169700/ambient-air-pollution-and-the-dynamic-transitions-of-stroke-and-dementia-a-population-based-cohort-study
#55
JOURNAL ARTICLE
Jiawei Wang, Xin Hu, Teng Yang, Jianbo Jin, Junwei Hao, Frank J Kelly, Jing Huang, Guoxing Li
BACKGROUND: Stroke and dementia are the leading causes of neurological disease burden. Detrimental effects of air pollution on both conditions are increasingly recognised, while the impacts on the dynamic transitions have not yet been explored, and whether critical time intervals exist is unknown. METHODS: This prospective study was conducted based on the UK Biobank. Annual average air pollution concentrations at baseline year 2010 estimated by land-use regression models were used as a proxy for long-term air pollution exposure...
January 2024: EClinicalMedicine
https://read.qxmd.com/read/38168307/exome-wide-tandem-repeats-confer-large-effects-on-subcortical-volumes-in-uk-biobank-participants
#56
Mary Anne Panoyan, Yuxin Shi, Cristina L Abbatangelo, Nina Adler, Ashley Moo-Choy, Esteban J Parra, Renato Polimanti, Pingzhao Hu, Frank R Wendt
The human subcortex is involved in memory and cognition. Structural and functional changes in subcortical regions is implicated in psychiatric conditions. We performed an association study of subcortical volumes using 15,941 tandem repeats (TRs) derived from whole exome sequencing (WES) data in 16,527 unrelated European ancestry participants. We identified 17 loci, most of which were associated with accumbens volume, and nine of which had fine-mapping probability supporting their causal effect on subcortical volume independent of surrounding variation...
December 11, 2023: medRxiv
https://read.qxmd.com/read/38163586/red-meat-intake-and-the-risk-of-cardiovascular-diseases-a-prospective-cohort-study-in-the-million-veteran-program
#57
JOURNAL ARTICLE
Dong D Wang, Yanping Li, Xuan-Mai Nguyen, Yuk-Lam Ho, Frank B Hu, Walter C Willett, Peter W F Wilson, Kelly Cho, J Michael Gaziano, Luc Djoussé
BACKGROUND: Red meat consumption was associated with increased risk of cardiovascular disease (CVD) in prospective cohort studies and a profile of biomarkers favoring high cardiovascular risk in short-term controlled trials. However, several recent systematic reviews and meta-analyses concluded with no or weak evidence for limiting red meat intake. OBJECTIVE: To prospectively examine the associations between red meat intake and incident CVD in an ongoing cohort study with diverse socioeconomic and racial/ethnic backgrounds...
December 30, 2023: Journal of Nutrition
https://read.qxmd.com/read/38154096/openmm-8-molecular-dynamics-simulation-with-machine-learning-potentials
#58
JOURNAL ARTICLE
Peter Eastman, Raimondas Galvelis, Raúl P Peláez, Charlles R A Abreu, Stephen E Farr, Emilio Gallicchio, Anton Gorenko, Michael M Henry, Frank Hu, Jing Huang, Andreas Krämer, Julien Michel, Joshua A Mitchell, Vijay S Pande, João Pglm Rodrigues, Jaime Rodriguez-Guerra, Andrew C Simmonett, Sukrit Singh, Jason Swails, Philip Turner, Yuanqing Wang, Ivy Zhang, John D Chodera, Gianni De Fabritiis, Thomas E Markland
Machine learning plays an important and growing role in molecular simulation. The newest version of the OpenMM molecular dynamics toolkit introduces new features to support the use of machine learning potentials. Arbitrary PyTorch models can be added to a simulation and used to compute forces and energy. A higher-level interface allows users to easily model their molecules of interest with general purpose, pretrained potential functions. A collection of optimized CUDA kernels and custom PyTorch operations greatly improves the speed of simulations...
December 28, 2023: Journal of Physical Chemistry. B
https://read.qxmd.com/read/38150249/low-carbohydrate-diet-macronutrient-quality-and-weight-change
#59
JOURNAL ARTICLE
Binkai Liu, Yang Hu, Sharan K Rai, Molin Wang, Frank B Hu, Qi Sun
IMPORTANCE: The associations of low-carbohydrate diets (LCDs) with long-term weight management remains unclear, and the source and quality of macronutrients within LCDs are less explored. OBJECTIVES: To prospectively examine associations between changes in LCD indices and weight change among US adults. DESIGN, SETTING, AND PARTICIPANTS: This prospective cohort study included initially healthy participants at baseline from the Nurses' Health Study (NHS; 1986-2010), Nurses' Health Study II (NHSII; 1991-2015), and Health Professionals Follow-up Study (HPFS; 1986-2018)...
December 1, 2023: JAMA Network Open
https://read.qxmd.com/read/38140605/tetherin-restricts-sars-cov-2-despite-the-presence-of-multiple-viral-antagonists
#60
JOURNAL ARTICLE
Elena Hagelauer, Rishikesh Lotke, Dorota Kmiec, Dan Hu, Mirjam Hohner, Sophie Stopper, Rayhane Nchioua, Frank Kirchhoff, Daniel Sauter, Michael Schindler
Coronavirus infection induces interferon-stimulated genes, one of which encodes Tetherin, a transmembrane protein inhibiting the release of various enveloped viruses from infected cells. Previous studies revealed that SARS-CoV encodes two Tetherin antagonists: the Spike protein (S), inducing lysosomal degradation of Tetherin, and ORF7a, altering its glycosylation. Similarly, SARS-CoV-2 has also been shown to use ORF7a and Spike to enhance virion release in the presence of Tetherin. Here, we directly compare the abilities and mechanisms of these two viral proteins to counteract Tetherin...
November 30, 2023: Viruses
keyword
keyword
169724
3
4
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.