Xin Wang, Qi Ding, Robin R Groleau, Luling Wu, Yuantao Mao, Feida Che, Oxana Kotova, Eoin M Scanlan, Simon E Lewis, Ping Li, Bo Tang, Tony D James, Thorfinnur Gunnlaugsson
The identification and detection of disease-related biomarkers is essential for early clinical diagnosis, evaluating disease progression, and for the development of therapeutics. Possessing the advantages of high sensitivity and selectivity, fluorescent probes have become effective tools for monitoring disease-related active molecules at the cellular level and in vivo . In this review, we describe current fluorescent probes designed for the detection and quantification of key bioactive molecules associated with common diseases, such as organ damage, inflammation, cancers, cardiovascular diseases, and brain disorders...
May 17, 2024: Chemical Reviews