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JOURNAL ARTICLE
Therese Karlsson, Lisa Tuomi, Caterina Finizia
PURPOSE: Laryngeal cancer treated by radiotherapy results in many patients being left with an abnormal voice long-term. This prospective study aims to report efficacy of voice rehabilitation 5years postradiotherapy completion. METHODS: Seventy-seven patients were randomized into an intervention group (n = 37) or a control group (n = 40). Voice rehabilitation was administered postradiotherapy. Patients were followed at baseline, 12- and 60-month postradiotherapy with voice recordings assessed using GRBAS protocol (Grade, Roughness, Breathiness, Asthenia, Strain)...
April 29, 2024: Journal of Voice
#2
JOURNAL ARTICLE
Steven A Kaplan, Jared L Moss, Sheldon J Freedman
BACKGROUND: Patient outcomes were assessed 2 years after treatment with the Optilume BPH Catheter System, a minimally invasive surgical therapy for the treatment of lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). METHODS: One-hundred forty-eight adult males with symptomatic BPH were enrolled and randomized in a 2:1 fashion to Optilume BPH or Sham (100 Optilume BPH; 48 Sham). Long-term measures include International Prostate Symptom Score (IPSS), peak urinary flow rate (Qmax), Post-Void Residual Urine (PVR), quality of life measures and sexual function...
April 29, 2024: Prostate Cancer and Prostatic Diseases
#3
RANDOMIZED CONTROLLED TRIAL
Jenna Nitkowski, Timothy J Ridolfi, Sarah J Lundeen, Anna R Giuliano, Elizabeth Y Chiao, Maria E Fernandez, Vanessa Schick, Jennifer S Smith, Bridgett Brzezinski, Alan G Nyitray
Background Anal cancer disproportionately affects sexual and gender minority individuals living with HIV. High-resolution anoscopy (HRA) is an in-clinic procedure to detect precancerous anal lesions and cancer, yet prospective data on factors associated with HRA attendance are lacking. We examined whether anal HPV sampling at home versus in a clinic impacts HRA uptake and assessed HRA acceptability. Methods Sexual and gender minority individuals were randomised to home-based self-sampling or clinical sampling...
April 2024: Sexual Health
#4
JOURNAL ARTICLE
Samuel Ask, Kristina Schildmeijer, Viktor Kaldo, Amanda Hellström
AIM: The aim of this systematic review and meta-analysis was to explore and evaluate the effect of psychosocial interventions in improving sexual health outcomes among post-treatment patients with pelvic cancer. METHODS: Inclusion and exclusion criteria were pelvic cancer survivors; psychosocial interventions; studies with a control group and measures of sexual health. Five databases were searched for literature along with an inspection of the included studies' reference lists to extend the search...
April 29, 2024: Acta Oncologica
#5
JOURNAL ARTICLE
Abdul Majid Khan, Muhammad Altaf, Tanveer Hussain, M Haroon Hamed, Umaira Safdar, Amina Ayub, Zaibun-Nisa Memon, Adnan Hafiz, Sana Ashraf, Muhammad Shoaib Amjad, Muhammad Majeed, Musheerul Hassan, Rainer W Bussmann, Arshad Mahmood Abbasi, Mohamed Al-Yafrsi, Hosam O Elansary, Eman A Mahmoud
INTRODUCTION: The utilization of fauna and fauna-based byproducts in ethnomedicinal usages has been a longstanding human activity, practiced across various cultures worldwide. This study focuses on investigating the utilization of animal-based traditional medicine by the people of Pakistan, specifically in the Gujranwala area. METHODS: Data collection took place from January to September 2019 through interviews with local communities. Ethnomedicinal applications of animal products were analyzed using several indices, including Relative Frequency of Citation (RFC), Relative Popularity Level (RPL), Folk Use Value (FL), and Relative Occurrence Percentage (ROP)...
2024: Frontiers in Veterinary Science
#6
JOURNAL ARTICLE
Azuka P Okwuraiwe, Ebere L Ogbonne, Anthony O Adeniyi, Patrick I Ihurhe, Blessing O Musa, Temilade R Abe, Opeoluwa O Shodipe, Rosemary A Audu
Introduction The World Health Organization states that almost all cervical cancer cases are linked to infection with high-risk human papillomaviruses transmitted through sexual contact. Implementing effective surveillance and preventive measures would enable the prevention of most cervical cancer cases, especially in HIV-infected women. Every year, about 12,000 women in Nigeria are diagnosed, with almost 8,000 deaths. HPV cervical cancer testing capacity is low in Nigeria. Testing scale-up and sensitization efforts across health facilities, including cervical tissue sample collection, are needed to reduce the cases of cervical cancer...
March 2024: Curēus
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JOURNAL ARTICLE
Atenchong Ngwibete, Olayinka Ogunbode, Laadi Terrumun Swende, Mangalu Mobhe Agbada, Akinyinka Omigbodun
INTRODUCTION: visual inspection is a low-cost screening strategy that can be used to prevent cervical cancer in women. These techniques can improve screening health outcomes for internally displaced women (IDW) who have poor sexual and reproductive health and rights' behaviors and outcomes. This study aimed to determine the prevalence of precancerous lesions and other clinical features using a visual inspection with acetic acid (VIA) technique during a cervical cancer screening campaign in two internally displaced people (IDP) camps in Benue State, Nigeria...
2024: Pan African Medical Journal
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JOURNAL ARTICLE
Andrea Cocci, Marta Pezzoli, Fernando Bianco, Franco Blefari, Pierluigi Bove, Francois Cornud, Gaetano De Rienzo, Paolo Destefanis, Danilo Di Trapani, Alessandro Giacobbe, Luca Giovanessi, Antonino Laganà, Giovanni Lughezzani, Guglielmo Manenti, Gianluca Muto, Gianluigi Patelli, Novello Pinzi, Stefano Regusci, Giorgio I Russo, Juan I M Salamanca, Matteo Salvi, Luigi Silvestri, Fabrizio Verweij, Eric Walser, Riccardo G Bertolo, Valerio Iacovelli, Alessandro Bertaccini, Debora Marchiori, Hugo Davila, Pasquale Ditonno, Paolo Gontero, Gennaro Iapicca, Theo M De Reijke, Vito Ricapito, Pierluca Pellegrini, Andrea Minervini, Sergio Serni, Francesco Sessa
OBJECTIVE: To evaluate transperineal laser ablation (TPLA) with Echolaser® (Echolaser® TPLA, Elesta S.p.A., Calenzano, Italy) as a treatment for benign prostatic hyperplasia (BPH) and prostate cancer (PCa) using the Delphi consensus method. METHODS: Italian and international experts on BPH and PCa participated in a collaborative consensus project. During two rounds, they expressed their opinions on Echolaser® TPLA for the treatment of BPH and PCa answering online questionnaires on indications, methodology, and potential complications of this technology...
April 2024: Asian Journal of Urology
#9
COMPARATIVE STUDY
Amru Sungkar, Kristanto Yuli Yarso, Didit Fajar Nugroho, Dian Ibnu Wahid, Chandra Analis Permatasari
INTRODUCTION: Breast cancer is a common disease that affects women globally and causes physical and emotional challenges. Breast reconstructive surgery aims to restore the shape of the breast after a mastectomy. Two common approaches used today are tissue-based or autologous and implant-based reconstruction. Autologous breast reconstruction has the advantage of being more affordable, but the resulting shape is less attractive. At the same time, the implant technique produces a more pleasing shape at a more expensive cost...
April 1, 2024: Asian Pacific Journal of Cancer Prevention: APJCP
#10
JOURNAL ARTICLE
H Çelik, H Aslan
BACKGROUND: Cancer patients have high supportive care needs related to the nature of the disease and treatment methods. To meet these needs or reduce symptoms, patients can be expected to resort to alternative treatment methods. AIM: To examine the relationship between the supportive care needs of cancer patients and their attitudes toward complementary and alternative medicine (CAM). METHODS: This was a cross-sectional study involving 289 cancer patients at the Oncology Hospital in east of Turkey...
April 1, 2024: Nigerian Journal of Clinical Practice
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REVIEW
Inês N R Mota, Setareh Satari, Inês Soares Marques, Joana M O Santos, Rui Medeiros
Cancer-associated cachexia (CAC) is a complex multiple organ syndrome that significantly contributes to reduced quality of life and increased mortality among many cancer patients. Its multifactorial nature makes its early diagnosis and effective therapeutic interventions challenging. Adipose tissue is particularly impacted by cachexia, typically through increased lipolysis, browning and thermogenesis, mainly at the onset of the disease. These processes lead to depletion of fat mass and contribute to the dysfunction of other organs...
April 26, 2024: Biochimica et Biophysica Acta. Reviews on Cancer
#12
JOURNAL ARTICLE
Arnold Hagens, Albertus Constantijn Sloof, Roksana Janghorban
This study aimed to determine the cost-effectiveness of vaccination against HPV. An age-sex structured dynamic disease transmission model was created to estimate the spread of HPV and the HPV-related incidence of cervical cancer (CC) in Iran. Sixteen age groups of men and women were incorporated to reflect the differences in sexual preferences, vaccination uptake, and disease-related outcomes. Three scenarios were evaluated by using an Incremental Cost-Effectiveness Ratio (ICER) with gained quality-adjusted life years (QALYs)...
April 18, 2024: Vaccines
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JOURNAL ARTICLE
Marte Pettersen Mikalsen, Gunnar Skov Simonsen, Sveinung Wergeland Sørbye
BACKGROUND: Human papillomavirus (HPV), the most prevalent sexually transmitted infection globally, is a key risk factor for high-grade cervical lesions and cervical cancer. Since 2009, HPV vaccination has been part of the national immunization program for girls in 7th grade in Norway (women born 1997 and later). This study aimed to assess the impact of HPV vaccination on the incidence of high-grade cervical precursors (CIN2+) among women aged 20-25 in Troms and Finnmark over a 15-year period...
April 16, 2024: Vaccines
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JOURNAL ARTICLE
E Marshall Brooks, Kendall Fugate-Laus, Ben Webel, Shillpa Naavaal
Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States; yet, despite the availability of safe and effective HPV vaccines, only half of eligible adolescents have completed the vaccine series. School-entry requirements are one proven strategy to increase vaccination rates among children and youth and reduce the burden of HPV-related cancer. This study investigated community perceptions of an HPV vaccine school-entry mandate in Virginia and the consequences of a low threshold exemption option included in the legislation...
April 10, 2024: Vaccines
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REVIEW
Jihye Choi, Efrat K Gabay, Paula M Cuccaro
School nurses are uniquely positioned to educate students about immunizations, including human papillomavirus (HPV) vaccination, but schools are often without a nurse for different reasons. In lieu of nurses, teachers who closely interact with students and are traditionally well-trusted by parents may be able to communicate about HPV vaccination, alleviating parental vaccine hesitancy. This systematic review explores school teachers' perspectives on adolescent HPV vaccination and factors influencing their willingness to make vaccine recommendations...
March 27, 2024: Vaccines
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REVIEW
Massimiliano Raffo, Angelo Di Naro, Luigi Napolitano, Achille Aveta, Simone Cilio, Savio Domenico Pandolfo, Celeste Manfredi, Chiara Lonati, Nazareno Roberto Suardi
The incidence of testicular cancer (TC) has been rapidly increasing over the past years. Diagnosis and early treatment have shown good oncological control, guaranteeing the patient different treatment approaches according to histology and tumor stage. Currently, physicians usually prioritize oncological outcomes over sexual outcomes and quality of life, considering as a first aim the overall survival of the patients; however, differently from other neoplasms, quality of life is still strongly affected among TC patients, and sexual outcomes are frequently compromised after each TC treatment...
March 31, 2024: Medicina
#17
JOURNAL ARTICLE
Junkyu Park, Sujin Shin, Youngmin Bu, Ho-Young Choi, Kyungjin Lee
Cnidium monnieri (L.) Cusson, a member of the Apiaceae family, is rich in coumarins, such as imperatorin and osthole. Cnidium monnieri fruit (CM) has a broad range of therapeutic potential that can be used in anti-bacterial, anti-cancer, and sexual dysfunction treatments. However, its efficacy in lowering blood pressure through vasodilation remains unknown. This study aimed to assess the potential therapeutic effect of CM 50% ethanol extract (CME) on hypertension and the mechanism of its vasorelaxant effect...
April 11, 2024: International Journal of Molecular Sciences
#18
JOURNAL ARTICLE
Lauren V Ghazal, Hailey Johnston, Elisabeth Dodd, Yasmine Ramachandra, Nicholas Giallourakis, Kayla Fulginiti, Charles Kamen
Sexual and gender diverse (SGD) adolescent and young adult (AYA) cancer survivors are an increasing and vulnerable group with unique needs that often remain unmet in the healthcare system. This paper describes the conceptualization and development of a community-based organization dedicated to serving SGD AYAs, in addition to reporting on the results of a community-led needs assessment. A total of 56 SGD AYA community members completed the online survey. Most participants were between the ages of 26 to 33, identified as white, cisgender, bisexual women, and had hematologic malignancies...
March 30, 2024: International Journal of Environmental Research and Public Health
#19
REVIEW
Erica Silvestris, Stella D'Oronzo, Easter Anna Petracca, Claudia D'Addario, Gennaro Cormio, Vera Loizzi, Stefano Canosa, Giacomo Corrado
In recent years, immuno-oncology has revolutionized the cancer treatment field by harnessing the immune system's power to counteract cancer cells. While this innovative approach holds great promise for improving cancer outcomes, it also raises important considerations related to fertility and reproductive toxicity. In fact, most young females receiving gonadotoxic anti-cancer treatments undergo iatrogenic ovarian exhaustion, resulting in a permanent illness that precludes the vocation of motherhood as a natural female sexual identity...
April 19, 2024: Journal of Personalized Medicine
#20
Dominika Januś, Monika Kujdowicz, Konrad Kaleta, Kamil Możdżeń, Jan Radliński, Anna Taczanowska-Niemczuk, Aleksandra Kiszka-Wiłkojć, Marcin Maślanka, Wojciech Górecki, Jerzy B Starzyk
BACKGROUND: DICER1, a cancer predisposition syndrome (CPS), seems to escape timely diagnosis in pediatric patients. Case report 1: A 16-year-old female patient was referred to the endocrinology ward due to a large goiter. Her medical history indicated normal sexual maturation, with menarche occurring at 13.5 years. Over the past 2.5 years, she had developed pronounced androgenic symptoms, including a deepened male voice; facial, back, and neckline acne; hirsutism; and menstrual irregularities leading to secondary amenorrhea...
March 28, 2024: Children
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