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https://read.qxmd.com/read/30878125/early-colorectal-cancer-diagnosis-treatment-and-survivorship-care
#1
REVIEW
Gabriella Buccafusca, Ilaria Proserpio, Antonino Carmelo Tralongo, Sebastiano Rametta Giuliano, Paolo Tralongo
CRC is the third most commonly diagnosed malignancy and the fourth leading cause of cancer-related death in the world. With advances in treatment, colorectal cancer is being transformed from a deadly disease to an illness that is increasingly curable. With this transformation has come increased interest in the unique problems, risks, needs, and concerns of survivors who have completed treatment and are cancer-free. They often suffer late/long-term side effects of therapies that may compromise their QoL such as fatigue, sleep difficulty, fear of recurrence, anxiety, depression, negative body image, sensory neuropathy, gastrointestinal problems, urinary incontinence, and sexual dysfunction...
April 2019: Critical Reviews in Oncology/hematology
https://read.qxmd.com/read/30876496/utilizing-the-patient-reported-outcomes-measurement-information-system-promis%C3%A2-to-increase-referral-to-ancillary-support-services-for-severely-symptomatic-patients-with-gynecologic-cancer
#2
Gregory M Gressel, Shayan M Dioun, Michael Richley, David W Lounsbury, Bruce D Rapkin, Sara Isani, Nicole S Nevadunsky, D Y S Kuo, Akiva P Novetsky
OBJECTIVE: The Patient-Reported Outcomes Measurement Information System (PROMIS®) Network has developed a comprehensive repository of electronic patient reported outcomes measures (ePROs) of major symptom domains that have been validated in cancer patients. Their use for patients with gynecologic cancer has been understudied. Our objective was to establish feasibility and acceptability of PROMIS ePRO integration in a gynecologic oncology outpatient clinic and assess if it can help identify severely symptomatic patients and increase referral to supportive services...
March 2019: Gynecologic Oncology
https://read.qxmd.com/read/30875285/perplexity-of-penile-rehabilitation-following-radical-prostatectomy
#3
REVIEW
Jonathan Clavell-Hernandez, Bahadır Ermeç, Ateş Kadıoğlu, Run Wang
Radical prostatectomy has significantly improved prostate cancer survival rates but continues to have a negative impact on the patient's erectile function (EF). In attempts to improve erectile dysfunction (ED), clinicians have incorporated different treatment modalities to restore EF. Penile rehabilitation consists of understanding the mechanisms that affect post-prostatectomy EF and utilizing pharmacologic agents, devices, and interventions to promote the male sexual function. This article aims to summarize the available scientific research involving penile rehabilitation...
January 22, 2019: Turkish Journal of Urology
https://read.qxmd.com/read/30874977/sexual-behaviors-and-health-practices-among-student-service-members-and-veterans
#4
David L Albright, Antoinette A Landor, Justin T McDaniel, Kelli Godfrey, Kari L Fletcher, Kate H Thomas, Jessica Bertram
The purpose of the study was to determine whether veteran students and non-veteran students differed in their sexual behaviors and health practices and, furthermore, whether or not those differences were gender specific. Demographic characteristics of the study sample were explored by calculating frequencies and percentages by military service status. Research questions were explored with maximum likelihood multiple logistic regression. Results showed that student veterans were more likely than non-veteran students to have sex with multiple partners, with males and transgender students more likely than females to report multiple sexual partners...
March 11, 2019: Archives of Sexual Behavior
https://read.qxmd.com/read/30874326/beyond-the-responsibility-binary-analysing-maternal-responsibility-in-the-human-papillomavirus-vaccination-decision
#5
Katelin Albert
With the human papillomavirus (HPV) vaccine positioned as the "right tool" to protect girls' health and sexual health, public discourse positions parents as "responsible" if they vaccinate, "irresponsible" if they do not. The problem with this binary, however, is that it cannot account for the full spectrum of responsibilities and social norms that parents enact in vaccine decisions. In this paper, and in the context of low HPV vaccination rates, I confront this binary and encourage a fuller view of adolescent health and sexual health...
March 15, 2019: Sociology of Health & Illness
https://read.qxmd.com/read/30873091/couples-dealing-with-pediatric-blood-cancer-a-study-on-the-role-of-dyadic-coping
#6
Marieke Van Schoors, Tom Loeys, Liesbet Goubert, Geertrui Berghmans, Britt Ooms, Jurgen Lemiere, Koenraad Norga, Lesley Liliane Verhofstadt
Objective: Pediatric cancer is a life-threatening disease that poses significant challenges to the ill child and his/her parents. Among the studies investigating risk and protective factors for the individual and relationship adjustment of parents being confronted with pediatric cancer, couple factors - such as dyadic coping - gained little research attention. Therefore, the aim of the current study was to explore the association between dyadic coping and individual/relationship outcomes of parents in the context of pediatric cancer...
2019: Frontiers in Psychology
https://read.qxmd.com/read/30872561/bilateral-prophylactic-mastectomy-in-brca-mutation-carriers-what-surgeons-need-to-know
#7
EDITORIAL
Gianluca Franceschini, Alba Di Leone, Daniela Terribile, Martin Alessandro Sanchez, Riccardo Masetti
Aim of this paper is to allows to analyze a topic of great relevance and media interest such as the role of prophylactic mastectomy in healthy women with BRCA mutation proposing to the surgeons some useful informations for decision-making. Less than 15% of all breast cancers are associated with germline genetic mutations. The majority of hereditary breast tumors are due to mutations in BRCA1 and BRCA2 genes that are responsible for only one third of hereditary cases. The risk estimates are extremely heterogeneous with a mean cumulative lifetime breast cancer risk of approximately 72% in BRCA1 and 69% in BRCA2 by age 80...
2019: Annali Italiani di Chirurgia
https://read.qxmd.com/read/30871929/-we-are-muslims-and-these-diseases-don-t-happen-to-us-a-qualitative-study-of-the-views-of-young-somali-men-and-women-concerning-hpv-immunization
#8
Rebekah Pratt, Sharon W Njau, Channelle Ndagire, Nicole Chaisson, Sharondeep Toor, Nimo Ahmed, Saida Mohamed, Jay Dirks
BACKGROUND: Minnesota is home to the largest Somali immigrant population in the United States. Despite high rates of cervical cancer in this population, immunization rates for the human papillomavirus (HPV) are among the lowest in the nation. Targeting Somali young adults for catch-up vaccinations may be an important strategy for addressing these low rates. This study sought to understand the views of Somali young adults regarding HPV immunization. METHODS: Four focus groups (N = 34; 21 women) were conducted at an urban clinic in Minnesota...
March 11, 2019: Vaccine
https://read.qxmd.com/read/30871843/sexuality-and-menopause-unique-issues-in-gynecologic-cancer
#9
REVIEW
Melinda G Harris
OBJECTIVE: To provide current evidence on treatment- and disease-related sexual health concerns of women with gynecologic cancers. DATA SOURCES: Literature from 2006-2017 from MEDLINE, and PubMed databases. CONCLUSION: There are both physiologic and psychosocial sexual health sequelae among women treated for gynecologic cancer, including induced menopause. The management of symptoms requires communication between provider and patient because the effects can be long lasting and directly affect the patient's quality of life...
March 11, 2019: Seminars in Oncology Nursing
https://read.qxmd.com/read/30870844/hpv-vaccine-updates-and-highlights
#10
REVIEW
Cristina Mendes de Oliveira, José Humberto T G Fregnani, Luisa Lina Villa
HPV is the most common sexually transmitted biological agent and is the cause of many conditions in men and women, including precancer lesions and cancer. Three prophylactic HPV vaccines targeting high-risk HPV types are available in many countries worldwide: 2-, 4- and 9-valent vaccines. All the 3 vaccines use recombinant DNA technology and are prepared from the purified L1 protein that self-assembles to form HPV type-specific empty shells. This non-systematic review aims to summarize the HPV epidemiology and the vaccine development to review the landmark trials of HPV vaccine, to present to most remarkable results from clinical trials and the real world, and to stress the challenges and the barriers for HPV vaccine implementation...
March 14, 2019: Acta Cytologica
https://read.qxmd.com/read/30870497/factors-affecting-utilization-of-cervical-cancer-screening-services-among-women-attending-public-hospitals-in-tigray-region-ethiopia-2018-case-control-study
#11
Hirut Teame, Lemlem Gebremariam, Tsega Kahsay, Kidanemaryam Berhe, Gdiom Gebreheat, Gebrehiwot Gebremariam
BACKGROUND: Incidence and mortality of cervical cancer is the leading cancer among women in Ethiopia. Absence of effective detection methods and treatment strategies is a major reason for the sharply rising cervical cancer rates in developing countries. OBJECTIVE: To determine factors affecting utilization of cervical cancer screening services among women attending public hospitals in Tigray region in 2018. METHODS: Hospital based unmatched case control study was applied with sample size of 312 cases and 312 controls...
2019: PloS One
https://read.qxmd.com/read/30868975/prevalence-and-genotypes-of-anal-human-papillomavirus-infection-among-hiv-positive-vs-hiv-negative-men-in-taizhou-china
#12
X Liu, H Lin, X Chen, W Shen, X Ye, Y Lin, Z Lin, S Zhou, M Gao, Y Ding, N He
This study aims to investigate the prevalence and genotype distribution of anal human papillomavirus (HPV) infection among men with different sexual orientations with or without human immunodeficiency virus (HIV) in China. A cross-sectional study was conducted during 2016-2017 in Taizhou City, Zhejiang Province. Convenient sampling was used to recruit male participants from HIV voluntary counselling and testing clinics and Center for Disease Control and Prevention. A face-to-face questionnaire interview was administered and an anal-canal swab was collected for HPV genotyping...
January 2019: Epidemiology and Infection
https://read.qxmd.com/read/30866074/factors-related-to-self-rated-health-and-life-satisfaction-one-year-after-radical-prostatectomy-for-localised-prostate-cancer-a-cross-sectional-survey
#13
Anna-Maija Talvitie, Hanna Ojala, Teuvo Tammela, Anna-Maija Koivisto, Ilkka Pietilä
BACKGROUND: Localised prostate cancer affects patient's quality of life in many ways. The aim of this study was to explore factors related to self-rated health and life satisfaction for patients treated for prostate cancer, and to compare the results of these generic quality-of-life measures to the prostate cancer-specific quality-of-life measure (UCLA Prostate Cancer Index), which focuses on physical functioning. MATERIAL AND METHODS: This cross-sectional survey was carried out among 183 men who underwent radical prostatectomy in 2012-2015 at a university hospital in Finland and were seen 1 year postsurgery...
March 13, 2019: Scandinavian Journal of Caring Sciences
https://read.qxmd.com/read/30863974/hpv-vaccination-and-korean-american-college-women-cultural-factors-knowledge-and-attitudes-in-cervical-cancer-prevention
#14
Minjin Kim, Haeok Lee, Peter Kiang, Teri Aronowitz, Lisa Kennedy Sheldon, Ling Shi, Sun Kim, Jeroan Allison
Human papillomavirus (HPV) is the most prevalent sexually transmitted infection that leads to nearly all cervical cancers in the United States (U.S.), which could be prevented with the HPV vaccine. Korean American women experience a high burden of cervical cancer, but little is known about their awareness, knowledge, attitudes, sociocultural factors and social network/support related to intention to obtain the HPV vaccine. This study reports baseline characteristics of 104 Korean American college women aged 18-26 and who have not been previously vaccinated against HPV, as part of a pilot randomized controlled trial testing feasibility, acceptability, and preliminary effectiveness of an HPV storytelling intervention...
March 12, 2019: Journal of Community Health
https://read.qxmd.com/read/30863622/sexually-transmitted-infections-the-silent-partner-in-hiv-infected-women-in-zimbabwe
#15
Sara Lowe, Tinashe Mudzviti, Ardele Mandiriri, Tinei Shamu, Petronella Mudhokwani, Cleophas Chimbetete, Ruedi Luethy, Margaret Pascoe
Background: Coinfection rates of HIV and sexually transmitted infections (STIs) are not widely reported in Zimbabwe and no local guidelines regarding the screening of STIs in people living with HIV exist. Objectives: This cross-sectional study was conducted to determine the prevalence and associated risk factors for STI coinfection in a cohort of HIV-infected women. Methods: Between January and June 2016, 385 HIV-infected women presenting for routine cervical cancer screening were tested for five STIs: Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), Trichomonas vaginalis (TV), Herpes Simplex Virus (HSV) type 2 and Treponema pallidum (TP)...
2019: Southern African Journal of HIV Medicine
https://read.qxmd.com/read/30861021/high-fat-diet-induces-sex-specific-differential-gene-expression-in-drosophila-melanogaster
#16
Tsering Stobdan, Debashis Sahoo, Priti Azad, Iain Hartley, Erilynn Heinrichsen, Dan Zhou, Gabriel G Haddad
Currently about 2 billion adults globally are estimated to be overweight and ~13% of them are obese. High fat diet (HFD) is one of the major contributing factor to obesity, heart disease, diabetes and cancer. Recent findings on the role of HFD in inducing abnormalities in neurocognition and susceptibility to Alzheimer's disease are highly intriguing. Since fundamental molecular pathways are often conserved across species, studies involving Drosophila melanogaster as a model organism can provide insight into the molecular mechanisms involving human disease...
2019: PloS One
https://read.qxmd.com/read/30858829/psychosocial-issues-in-long-term-survivors-of-testicular-cancer
#17
REVIEW
Giuseppe Schepisi, Silvia De Padova, Delia De Lisi, Chiara Casadei, Elena Meggiolaro, Federica Ruffilli, Giovanni Rosti, Cristian Lolli, Giorgia Ravaglia, Vincenza Conteduca, Alberto Farolfi, Luigi Grassi, Ugo De Giorgi
Testicular cancer is the most frequent tumor in young males aged 15-39 years. As cure rates are currently around 90%, the prevalence of survivors is increasing. However, a disease-free condition does not necessarily correspond to a life free of physical and psychosocial health problems. The aim of this review was to explore psychosocial morbidity among testicular cancer survivors. A literature search was conducted in three electronic databases (PubMed, Medline, and Embase). The results of the search on cancer survivors were then combined with those of the search on psychosocial concerns and work performance...
2019: Frontiers in Endocrinology
https://read.qxmd.com/read/30858783/determinants-of-high-risk-human-papillomavirus-infection-in-anogenital-warts
#18
Goknur Ozaydin-Yavuz, Serap Gunes Bilgili, Huseyin Guducuoglu, Ibrahim Halil Yavuz, Sema Elibuyuk-Aksac, Ayse Serap Karadag
Introduction: Genital warts are benign epithelial tumours caused by human papilloma viruses (HPV), and are sexually transmitted. Genotyping of genital HPV bears great clinical significance in terms of treatment planning, follow-up, and prevention strategies. Aim: To evaluate the distribution of high-risk HPV infection types in patients diagnosed with anogenital warts. Material and methods: A total of 66 patients with anogenital warts were enrolled...
February 2019: Postȩpy Dermatologii i Alergologii
https://read.qxmd.com/read/30858073/late-onset-hypogonadism-and-testosterone-therapy-a-summary-of-guidelines-from-the-american-urological-association-and-the-european-association-of-urology
#19
Mikkel Fode, Andrea Salonia, Suks Minhas, Arthur L Burnett, Alan W Shindel
Men with low serum testosterone and symptoms of androgen deficiency may be diagnosed with testosterone deficiency. This condition is associated with metabolic syndrome and cardiovascular disease. The benefits (eg, improvement in sexual function) and risks (eg, prostate cancer and cardiovascular disease) of testosterone therapy are controversial. The American Urological Association and European Association of Urology guidelines on testosterone therapy differ on several points of management, likely reflecting the ambiguities surrounding testosterone therapy in practice...
March 8, 2019: European Urology Focus
https://read.qxmd.com/read/30857758/patient-reported-quality-of-life-following-stereotactic-body-radiotherapy-and-conventionally-fractionated-external-beam-radiotherapy-compared-with-active-surveillance-among-men-with-localized-prostate-cancer
#20
Dominic H Moon, Ram S Basak, Deborah S Usinger, Gregg A Dickerson, David E Morris, Mark Perman, Maili Lim, Turner Wibbelsman, Jerry Chang, Zachary Crawford, James R Broughman, Paul A Godly, Ronald C Chen
BACKGROUND: Evidence supporting the efficacy of stereotactic body radiotherapy (SBRT) for localized prostate cancer is accumulating, but comparative studies of patient-reported quality of life (QOL) following SBRT versus conventionally fractionated external beam radiotherapy (EBRT) or active surveillance (AS) are limited. OBJECTIVE: To compare QOL of patients pursuing SBRT and EBRT versus AS. DESIGN, SETTING, AND PARTICIPANTS: A population-based cohort of 680 men with newly diagnosed localized prostate cancer was prospectively enrolled from 2011 to 2013...
March 8, 2019: European Urology
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