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JOURNAL ARTICLE
Buğra İlhan, Göksu Bozdereli Berikol, Halil Doğan, Attila Beştemir, Adnan Kaya
BACKGROUND: To evaluate the prognostic accuracy of the Get With The Guidelines-Heart Failure (GWTG-HF) score, Shock Index (SI), Modified Shock Index (MSI), and Age Shock Index (Age-SI) alone and with lactate in patients with acute symptomatic heart failure (HF). METHODS: A retrospective cohort study was conducted in the emergency department of a tertiary hospital between January 1, 2019, and December 31, 2019. Patients aged >18 years and diagnosed with acute symptomatic HF were consecutively included in the study...
April 17, 2024: Anatolian Journal of Cardiology
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JOURNAL ARTICLE
Young-Ji Seo, Nikhil Chervu, Peyman Benharash, James X Wu
BACKGROUND: Thyroid storm is a rare but potentially lethal manifestation of thyrotoxicosis. Guidelines recommend nonoperative management of thyroid storm, but thyroidectomy can be performed if patients fail medical therapy or need immediate resolution of the storm. Outcomes of thyroidectomy for management of thyroid storm remain ill-defined. METHODS: Using the National Inpatient Sample from 2016 to 2020, a retrospective analysis was conducted of patients admitted with thyroid storm...
April 17, 2024: American Surgeon
#63
REVIEW
Antonia Sambola, Sigrun Halvorsen, David Adlam, Christian Hassager, Susanna Price, Giuseppe Rosano, Francois Schiele, Lene Holmvang, Marta de Riva, Amina Rakisheva, Patrick Sulzgruber, Eva Swahn
Cardiac emergencies in women, such as acute coronary syndromes, acute heart failure, and cardiac arrest, are associated with a high risk of adverse outcomes and mortality. Although women historically have been significantly underrepresented in clinical studies of these diseases, the guideline-recommended treatment for these emergencies is generally the same for both sexes. Still, women are less likely to receive evidence-based treatment compared to men. Furthermore, specific diseases affecting predominantly or exclusively women, such as spontaneous coronary dissection, myocardial infarction with non-obstructive coronary arteries, takotsubo cardiomyopathy, and peripartum cardiomyopathy, require specialized attention in terms of both diagnosis and management...
March 2024: Eur Heart J Open
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JOURNAL ARTICLE
Rickesh B Karsan, Katie E O'Sullivan, Christopher J Lockhart, Christopher Austin
BACKGROUND: Infective endocarditis of the aortic valve can result in a wide range of destructive pathology beyond the valve leaflets and annulus which require careful surgical planning to provide appropriate debridement and reconstruction. Failure to do so can result in a failure of surgical treatment, recurrent infection and cardiac failure with concomitant high morbidity and mortality. CASE REPORT: We describe the case of a 45-year-old male with previous patch repair of a ventricular septal defect, who was diagnosed with sub-acute bacterial endocarditis of the native aortic valve and developed a new fistula from the aorta to the right ventricular outflow tract which...
April 16, 2024: Journal of Cardiothoracic Surgery
#65
MULTICENTER STUDY
Noemi Glarner, Christian Puelacher, Danielle M Gualandro, Mirjam Pargger, Gabrielle Huré, Silvia Maiorano, Ivo Strebel, Simona Fried, Daniel Bolliger, Luzius A Steiner, Andreas Lampart, Giovanna Lurati Buse, Edin Mujagic, Didier Lardinois, Christoph Kindler, Lorenz Guerke, Stefan Schaeren, Andreas Mueller, Martin Clauss, Andreas Buser, Angelika Hammerer-Lercher, Christian Mueller
INTRODUCTION: Cardiac complications after major noncardiac surgery are common and associated with high morbidity and mortality. How preoperative use of beta-blockers may impact perioperative cardiac complications remains unclear. METHODS: In a multicentre prospective cohort study, preoperative beta-blocker use was ascertained in consecutive patients at elevated cardiovascular risk undergoing major noncardiac surgery. Cardiac complications were prospectively monitored and centrally adjudicated by two independent experts...
June 2024: British Journal of Anaesthesia
#66
JOURNAL ARTICLE
Serdar Tütüncü, Manuel C Olma, Claudia Kunze, Joanna Dietzel, Johannes Schurig, Michael Rosenkranz, Robert Stingele, Matthias Maschke, Peter U Heuschmann, Paulus Kirchhof, Ulrich Laufs, Darius G Nabavi, Joachim Röther, Götz Thomalla, Roland Veltkamp, Matthias Endres, Karl Georg Haeusler
Heart failure (HF) is associated with poor outcome after stroke, but data from large prospective trials are sparse.We assessed the impact of HF on clinical endpoints in patients hospitalized with acute ischemic stroke or transient ischemic attack (TIA) enrolled in the prospective, multicenter Systematic Monitoring for Detection of Atrial Fibrillation in Patients with Acute Ischemic Stroke (MonDAFIS) trial. HF was defined as left ventricular ejection fraction (LVEF) < 55% or a history of HF on admission...
April 15, 2024: Internal and Emergency Medicine
#67
REVIEW
Goro Yoshioka, Atsushi Tanaka, Shinjo Sonoda, Tetsuya Kaneko, Hiroshi Hongo, Kensuke Yokoi, Masahiro Natsuaki, Koichi Node
Despite advances in multidisciplinary acute care for myocardial infarction (MI), the clinical need to manage heart failure and elevated mortality risks in the remote phase of MI remains unmet. Various prognostic models have been established using clinical indicators obtained during the acute phase of MI; however, most of these indicators also show chronic changes in the post-MI phase. Although relevant guidelines recommend follow-up assessments of some clinical indicators in the chronic phase, systematic reassessment has not yet been fully established and implemented in a real-world clinical setting...
April 14, 2024: Cardiovascular Intervention and Therapeutics
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JOURNAL ARTICLE
Anastasios Apostolos, Nikolaos Ktenopoulos, Dimitrios-David Chlorogiannis, Odysseas Katsaros, Konstantinos Konstantinou, Maria Drakopoulou, Sotirios Tsalamandris, Antonios Karanasos, Andreas Synetos, Georgios Latsios, Constantina Aggeli, Vasileios Panoulas, Costas Tsioufis, Konstantinos Toutouzas
Patients with severe aortic stenosis (AoS) often present with acute heart failure and compensation, frequently leading to cardiogenic shock. Transcatheter Aortic Valve Replacement (TAVR) has been recently performed as a bailout treatment in such patients. The aim of our meta-analysis is to compare urgent TAVR with elective procedures. We systematically screened three databases searching for studies comparing urgent vs elective TAVR. Primary endpoint is the 30-days mortality. Secondary endpoints included in-hospital mortality, device success, periprocedural vascular complications, 30-days stroke, 30-days acute kidney injury (AKI), permanent pacemaker implantation (PPM), moderate or severe paravalvular leakage, and 30-days bleeding...
April 13, 2024: Angiology
#69
JOURNAL ARTICLE
Ziv Dadon, Moshe Rav Acha, Amir Orlev, Shemy Carasso, Michael Glikson, Shmuel Gottlieb, Evan Avraham Alpert
INTRODUCTION: Point-of-care ultrasound has become a universal practice, employed by physicians across various disciplines, contributing to diagnostic processes and decision-making. AIM: To assess the association of reduced (<50%) left-ventricular ejection fraction (LVEF) based on prospective point-of-care ultrasound operated by medical students using an artificial intelligence (AI) tool and 1-year primary composite outcome, including mortality and readmission for cardiovascular-related causes...
April 4, 2024: Diagnostics
#70
JOURNAL ARTICLE
Malkiely Gal, Paran Maya, Kobo Ofer, Khan Mansoor, Abbou Benyamine, Kessel Boris
Background: Acute appendicitis (AA) in older individuals remains understudied. We aimed to assess AA characteristics in patients older than 60 years and evaluate the impact of comorbidities. Methods: This retrospective study analyzed data from the American National Inpatient Sample between 2016 and 2019 to compare AA characteristics in patients younger and older than 60 years. Results: Of the 538,400 patients included, 27.5% were older than 60 years. Younger patients had a higher appendectomy rate ( p < 0...
April 8, 2024: Journal of Clinical Medicine
#71
JOURNAL ARTICLE
Koray Durak, Katharina Nubbemeyer, Rashad Zayat, Jan Spillner, Slavena Dineva, Sebastian Kalverkamp, Alexander Kersten
Background : Abnormal liver function tests can identify severe cardiopulmonary failure. The aspartate transaminase/alanine transaminase (AST/ALT) ratio, or the De Ritis ratio, is commonly used to evaluate acute liver damage. However, its prognostic value in pulmonary embolism (PE) is unknown. Methods : Two cohorts, including patients with intermediate- and high-risk PEs, were established: one with an abnormal baseline AST/ALT ratio (>1) and another with a normal baseline AST/ALT ratio (<1). The primary outcome was a 60-day mortality...
April 4, 2024: Journal of Clinical Medicine
#72
JOURNAL ARTICLE
Leonardo Belfioretti, Matteo Francioni, Ilaria Battistoni, Luca Angelini, Maria Vittoria Matassini, Giulia Pongetti, Matilda Shkoza, Luca Piangerelli, Tommaso Piva, Elisa Nicolini, Alessandro Maolo, Andi Muçaj, Paolo Compagnucci, Christopher Munch, Antonio Dello Russo, Marco Di Eusanio, Marco Marini
Background: The management of cardiogenic shock (CS) after ACS has evolved over time, and the development of a multidisciplinary team-based approach has been shown to improve outcomes, although mortality remains high. Methods: All consecutive patients with ACS-CS admitted at our CICU from March 2012 to July 2021 were included in this single-center retrospective study. In 2019, we established a "shock team" consisting of a cardiac intensivist, an interventional cardiologist, an anesthetist, and a cardiac surgeon...
April 3, 2024: Journal of Clinical Medicine
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JOURNAL ARTICLE
Giulia Nardi, Enrico Marchi, Marco Allinovi, Gianmarco Lugli, Lucrezia Biagiotti, Francesca Maria Di Muro, Renato Valenti, Iacopo Muraca, Benedetta Tomberli, Niccolò Ciardetti, Brunetto Alterini, Francesco Meucci, Carlo Di Mario, Alessio Mattesini
(1) Background : This single-center retrospective study aimed to evaluate whether sodium-glucose cotransporter-2 inhibitors (SGLT2-i) therapy may have a nephroprotective effect to prevent contrast-induced acute kidney injury (CI-AKI) in patients with heart failure (HF) undergoing iodinated contrast medium (ICM) invasive procedures. (2) Methods : The population was stratified into SGLT2-i users and SGLT2-i non-users according to the chronic treatment with gliflozins. The primary endpoint was CI-AKI incidence during hospitalization...
April 1, 2024: Journal of Clinical Medicine
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JOURNAL ARTICLE
Mariarosaria Magaldi, Erika Nogue, Nicolas Molinari, Nicola De Luca, Anne-Marie Dupuy, Florence Leclercq, Jean-Luc Pasquie, Camille Roubille, Grégoire Mercier, Jean-Paul Cristol, François Roubille
Background : Acute heart failure (AHF) represents a leading cause of unscheduled hospital stays, frequent rehospitalisations, and mortality worldwide. The aim of our study was to develop a bedside prognostic tool, a multivariable predictive risk score, that is useful in daily practice, thus providing an early prognostic evaluation at admission and an accurate risk stratification after discharge in patients with AHF. Methods : This study is a subanalysis of the STADE HF study, which is a single-centre, prospective, randomised controlled trial enrolling 123 patients admitted to hospital for AHF...
March 30, 2024: Journal of Clinical Medicine
#75
JOURNAL ARTICLE
Roham Hadidchi, Stephen H Wang, David Rezko, Sonya Henry, Patricia K Coyle, Tim Q Duong
BACKGROUND: Although certain subsets patients with multiple sclerosis (MS), an immune-mediated disorder, are at higher risk of worse acute COVID-19 outcomes compared to the general population, it is not clear whether SARS-CoV-2 infection impacts long-term outcomes compared with MS patients without COVID-19 infection. OBJECTIVES: This study investigated MS disease activity and mortality 3.5 years post SARS-CoV-2 infection and compared with MS patients without COVID-19...
April 8, 2024: Multiple Sclerosis and related Disorders
#76
JOURNAL ARTICLE
Anton O Bilchenko, Olga V Gritsenko, Volodymir O Kolisnyk, Oleg I Rafalyuk, Andrii V Pyzhevskii, Yaroslav V Myzak, Dmytro I Besh, Victor M Salo, Sergii O Chaichuk, Mykhailo O Lehoida, Ihor V Danylchuk, Ihor V Polivenok
BACKGROUND: Data on the results and management strategies in patients with acute myocardial infarction complicated by cardiogenic shock (AMI-CS) in the Low and Lower-Middle Income Countries (LLMICs) are limited. This lack of understanding of the situation partially hinders the development of effective cardiogenic shock treatment programs in this part of the world. MATERIALS AND METHODS: The Ukrainian Multicentre Cardiogenic Shock Registry was analyzed, covering patient data from 2021 to 2022 in 6 major Ukrainian reperfusion centres from different parts of the country...
2024: Frontiers in Cardiovascular Medicine
#77
JOURNAL ARTICLE
Lei Zhang, Yiwu Sun, Xin Sui, Jian Zhang, Jingshun Zhao, Runfeng Zhou, Wenjia Xu, Chengke Yin, Zhaoyi He, Yufei Sun, Chang Liu, Ailing Song, Fei Han
AIMS: Both hypercapnia and hypocapnia are common in patients with acute heart failure (AHF), but the association between partial pressure of arterial carbon dioxide (PaCO2 ) and AHF prognosis remains unclear. The objective of this study was to investigate the connection between PaCO2 within 24 h after admission to the intensive care unit (ICU) and mortality during hospitalization and at 1 year in AHF patients. METHODS AND RESULTS: AHF patients were enrolled from the Medical Information Mart for Intensive Care IV database...
April 11, 2024: ESC Heart Failure
#78
REVIEW
Zi-Ling Cai, Liao-Yao Wang, Bing-Yue Zhang, Ai-Song Zhu
OBJECTIVE: This study aimed to evaluate the methodological quality of existing meta-analyses (MAs) and the quality of evidence for outcome indicators to in order to provide an updated overview of the evidence concerning the therapeutic efficacy of the Mediterranean diet (MD) for various types of Cardiovascular diseases (CVD). DESIGN: We conducted comprehensive searches of PubMed, Cochrane Library, and Embase databases. The quality of the MAs was assessed using the A Measurement Tool to Assess Systematic Reviews 2(AMSTAR 2) checklist, while the Grading of Recommendations Assessment, Development and Evaluation (GRADE) evidence evaluation system was employed to evaluate the quality of evidence for significant outcomes...
April 11, 2024: Public Health Nutrition
#79
JOURNAL ARTICLE
H Schuermann, R von Rennenberg, C Riegler, I Rangus, S Litmeier, J F Scheitz, W Doehner, H Audebert, T B Braemswig, C H Nolte
BACKGROUND: Stroke is a severe complication of infective endocarditis (IE), associated with high rates of mortality. Data on how IE patients with and without stroke differ may help to improve understanding contributing mechanisms. METHODS: All patients treated for IE between 2019 and 2021 with and without associated stroke were identified from the medical records of three academic tertiary care hospitals in Germany, all part of Charité - Universitätsmedizin Berlin, Germany...
April 11, 2024: Neurological research and practice
#80
MULTICENTER STUDY
Marianna Adamo, Giulio Russo, Matteo Pagnesi, Edoardo Pancaldi, Hannes Alessandrini, Martin Andreas, Luigi P Badano, Daniel Braun, Kim A Connelly, Paolo Denti, Rodrigo Estevez-Loureiro, Neil Fam, Mara Gavazzoni, Rebecca T Hahn, Claudia Harr, Joerg Hausleiter, Dominique Himbert, Daniel Kalbacher, Edwin Ho, Azeem Latib, Edith Lubos, Sebastian Ludwig, Laura Lupi, Philipp Lurz, Vanessa Monivas, Georg Nickenig, Daniela Pedicino, Giovanni Pedrazzini, Alberto Pozzoli, Denise Pires Marafon, Roberta Pastorino, Fabien Praz, Joseph Rodes-Cabau, Christian Besler, Anne Rebecca Schöber, Joachim Schofer, Andrea Scotti, Kerstin Piayda, Horst Sievert, Gilbert H L Tang, Alessandro Sticchi, David Messika-Zeitoun, Holger Thiele, Florian Schlotter, Ralph Stephan von Bardeleben, John Webb, Julien Dreyfus, Stephan Windecker, Martin Leon, Francesco Maisano, Marco Metra, Maurizio Taramasso
BACKGROUND: Data on the prognostic role of the TRI-SCORE in patients undergoing transcatheter tricuspid valve intervention (TTVI) are limited. OBJECTIVES: The aim of this study was to evaluate the performance of the TRI-SCORE in predicting outcomes of patients undergoing TTVI. METHODS: TriValve (Transcatheter Tricuspid Valve Therapies) is a large multicenter multinational registry including patients undergoing TTVI. The TRI-SCORE is a risk model recently proposed to predict in-hospital mortality after tricuspid valve surgery...
April 8, 2024: JACC. Cardiovascular Interventions
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