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https://read.qxmd.com/read/30817410/driving-innovation-in-health-care-clinical-nurse-leader-role
#1
Kristen Noles, Rebekah Barber, David James, Nancy Wingo
BACKGROUND: The clinical nurse leader (CNL) role was developed as a strategy for redesigning care delivery to address quality and safety gaps in health care. However, innovation competencies have never been assessed in this group. PURPOSE: The purpose of this study was to determine whether CNLs have different perceptions of innovation and their own competence to lead it, compared with other nurse leaders. METHODS: A web-enabled concurrent mixed-method survey design was used to compare self-reported innovation competencies between nurses in a leadership role and certified CNLs at a large academic medical center...
February 25, 2019: Journal of Nursing Care Quality
https://read.qxmd.com/read/30710437/intersecting-policy-contexts-of-employment-related-geographical-mobility-of-healthcare-workers-the-case-of-nova-scotia-canada
#2
Shiva Nourpanah, Ivy Bourgeault, Lois Jackson, Sheri Price, Pauline Gardiner Barber, Michael P Leiter
Mobility and movement is an increasingly important part of work for many, however, Employment-Related Geographical Mobility (ERGM), defined as the extended movement of workers between places of permanent residence and employment, is relatively understudied among healthcare workers. It is critical to understand the policies that affect ERGM, and how they impact mobile healthcare workers. We outline four key intersecting policy contexts related to the ERGM of healthcare workers, focusing on the mobility of Registered Nurses (RNs), Licensed Practical Nurses (LPNs) and Continuing Care Assistants (CCAs) in Nova Scotia: international labour mobility and migration; interprovincial labour mobility; provincial credential recognition; and, workplace and occupational health and safety...
November 2018: Healthcare Policy
https://read.qxmd.com/read/30692242/home-use-of-day-and-night-hybrid-closed-loop-insulin-delivery-in-very-young-children-a-multicenter-3-week-randomized-trial
#3
Martin Tauschmann, Janet M Allen, Katrin Nagl, Maria Fritsch, James Yong, Emily Metcalfe, Dominique Schaeffer, Muriel Fichelle, Ulrike Schierloh, Alena G Thiele, Daniela Abt, Harald Kojzar, Julia K Mader, Sonja Slegtenhorst, Nicole Barber, Malgorzata E Wilinska, Charlotte Boughton, Gianluca Musolino, Judy Sibayan, Nathan Cohen, Craig Kollman, Sabine E Hofer, Elke Fröhlich-Reiterer, Thomas M Kapellen, Carlo L Acerini, Carine de Beaufort, Fiona Campbell, Birgit Rami-Merhar, Roman Hovorka
OBJECTIVE: We aimed to assess the feasibility and safety of hybrid closed loop insulin delivery in children with type 1 diabetes aged 1-7 years as well as evaluate the role of diluted insulin on glucose control. RESEARCH DESIGN AND METHODS: In an open-label, multicenter, multinational, randomized crossover study, 24 children with type 1 diabetes on insulin pump therapy (median age 5 years [interquartile range 3-6] and mean ± SD HbA1c 7.4 ± 0.7% [57 ± 8 mmol/mol] total insulin 13...
January 28, 2019: Diabetes Care
https://read.qxmd.com/read/30592662/sustainability-of-blood-pressure-reduction-in-black-barbershops
#4
Ronald G Victor, Ciantel A Blyler, Ning Li, Kathleen Lynch, Norma B Moy, Mohamad Rashid, L Cindy Chang, Joel Handler, Jeffrey Brettler, Florian Rader, Robert M Elashoff
BACKGROUND: We developed a new model of hypertension care for non-Hispanic black men that links health promotion by barbers to medication management by American Society of Hypertension-certified pharmacists and demonstrated efficacy in a 6-month cluster-randomized trial. The marked reduction in systolic blood pressure (BP) seen at 6 months warranted continuing the trial through 12 months to test sustainability, a necessary precondition for implementation research. METHODS: We enrolled a cohort of 319 black male patrons with systolic BP ≥140 mm Hg at baseline...
January 2, 2019: Circulation
https://read.qxmd.com/read/30570501/intraoperative-evaluation-of-urinary-tract-injuries-at-the-time-of-pelvic-surgery-a-systematic-review
#5
Lauren N Siff, Audra J Hill, Karl Jallad, Mary Pat Harnegie, Matthew D Barber
OBJECTIVE: The aim of this study was to determine the safety and efficacy of methods for intraoperative evaluation of urinary tract injury during pelvic surgery. METHODS: PubMed, EMBASE, CINAHL, Web of Science, Scopus, ProQuest, the Cochrane Library, and Clinicaltrials.gov were searched from 1947 to February 2018. Articles or abstracts describing the routine evaluation of urinary tract injuries during pelvic surgery in adults were included, surgical indications of urinary tract anomaly, stones, or malignancy were excluded...
December 19, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://read.qxmd.com/read/30552937/randomized-controlled-trial-of-aquablation-vs-transurethral-resection-of-the-prostate-in-benign-prostatic-hyperplasia-one-year-outcomes
#6
Peter Gilling, Neil Barber, Mohamed Bidair, Paul Anderson, Mark Sutton, Tev Aho, Eugene Kramolowsky, Andrew Thomas, Barrett Cowan, Claus Roehrborn
OBJECTIVE: To report 1-year safety and efficacy outcomes after either Aquablation or TURP for the treatment of lower urinary tract symptoms related to BPH. METHODS: This double-blinded, multicenter prospective randomized controlled trial assigned 181 patients with BPH-related moderate-to-severe lower urinary tract symptoms to either electrocautery-based prostate resection (TURP) or Aquablation. Efficacy endpoints included reduction in International Prostate Symptom Score and improvement in uroflow parameters...
December 12, 2018: Urology
https://read.qxmd.com/read/30507375/amisulpride-for-very-late-onset-schizophrenia-like-psychosis-the-atlas-three-arm-rct
#7
Robert Howard, Elizabeth Cort, Rosie Bradley, Emma Harper, Linda Kelly, Peter Bentham, Craig Ritchie, Suzanne Reeves, Waleed Fawzi, Gill Livingston, Andrew Sommerlad, Sabu Oomman, Ejaz Nazir, Ramin Nilforooshan, Robert Barber, Chris Fox, Ajay Macharouthu, Pranathi Ramachandra, Vivek Pattan, John Sykes, Valerie Curran, Cornelius Katona, Tom Dening, Martin Knapp, Renee Romeo, Richard Gray
BACKGROUND: Very late-onset (aged ≥ 60 years) schizophrenia-like psychosis (VLOSLP) occurs frequently but no placebo-controlled, randomised trials have assessed the efficacy or risks of antipsychotic treatment. Most patients are not prescribed treatment. OBJECTIVES: The study investigated whether or not low-dose amisulpride is superior to placebo in reducing psychosis symptoms over 12 weeks and if any benefit is maintained by continuing treatment thereafter...
November 2018: Health Technology Assessment: HTA
https://read.qxmd.com/read/30290000/omadacycline-enters-the-ring-a-new-antimicrobial-contender
#8
Katie E Barber, Alison M Bell, Mary Joyce B Wingler, Jamie L Wagner, Kayla R Stover
Omadacycline is a novel aminomethylcycline approved for the treatment of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections. This article reviews existing data pertaining to the biochemistry, mechanism of action, pharmacokinetics/pharmacodynamics, in vitro activity, and current progress with omadacycline in clinical trials. Omadacycline inhibits protein synthesis by binding to the 30S subunit of the bacterial ribosome at the tetracycline-binding site with an affinity similar to glycylcyclines...
December 2018: Pharmacotherapy
https://read.qxmd.com/read/30190234/a-comparison-of-safety-and-outcomes-with-cefazolin-versus-nafcillin-for-methicillin-susceptible-staphylococcus-aureus-bloodstream-infections
#9
Matthew A Miller, Douglas N Fish, Gerard R Barber, Michelle A Barron, Tiffany A Goolsby, Pierre Moine, Scott W Mueller
BACKGROUND: Methicillin-susceptible Staphylococcus aureus (MSSA) is a frequent cause of bloodstream infections (BSI). Treatment with nafcillin (NAF) has been preferred to cefazolin (CFZ). However, comparable outcomes have been found with CFZ with possibly lower risk for side-effects. This study compared safety and effectiveness of NAF versus CFZ for MSSA BSI. METHODS: This single center retrospective study evaluated adults admitted with MSSA BSI who received NAF or CFZ...
August 18, 2018: Journal of Microbiology Immunology and Infection
https://read.qxmd.com/read/29997314/the-relationship-of-safety-with-burnout-for-mobile-health-employees
#10
Michael P Leiter, Lois Jackson, Ivy Bourgeault, Sheri Price, Audrey Kruisselbrink, Pauline Gardiner Barber, Shiva Nourpanah
OBJECTIVE: The study examined the relationship of occupational safety with job burnout. DESIGN: The study used a cross-sectional survey design. SETTING: The setting was Nova Scotia, Canada. PARTICIPANTS: Mobile health employees ( N = 156) completed surveys on road safety, workload, burnout and supervisor incivility. MAIN OUTCOME MEASURE: The main outcome measure was the Maslach Burnout Inventory...
July 11, 2018: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/29982200/patient-safety-initiatives-in-obstetrics-a-rapid-review
#11
Jesmin Antony, Wasifa Zarin, Ba' Pham, Vera Nincic, Roberta Cardoso, John D Ivory, Marco Ghassemi, Sarah Louise Barber, Sharon E Straus, Andrea C Tricco
OBJECTIVES: This review was commissioned by WHO, South Africa-Country office because of an exponential increase in medical litigation claims related to patient safety in obstetrical care in the country. A rapid review was conducted to examine the effectiveness of quality improvement (QI) strategies on maternal and newborn patient safety outcomes, risk of litigation and burden of associated costs. DESIGN: A rapid review of the literature was conducted to provide decision-makers with timely evidence...
July 6, 2018: BMJ Open
https://read.qxmd.com/read/29934117/innovative-invasive-management-without-stent-implantation-guided-by-optical-coherence-tomography-in-acute-coronary-syndrome
#12
Geraud Souteyrand, Louis Viallard, Nicolas Combaret, Bruno Pereira, Guillaume Clerfond, Guilhem Malcles, Nicolas Barber Chamoux, Francesco Prati, Pascal Motreff
BACKGROUND: A two-step strategy of invasive management without stenting, guided by optical coherence tomography (OCT), in selected patients with acute coronary syndrome (ACS), might avoid systematic stent implantation and allow medical therapy alone. AIMS: To assess the feasibility and safety of such a procedure, and to define coronary imaging characteristics in a specific population. METHODS: This single-centre proof-of-concept study included all patients with ACS who benefited from a two-step revascularization procedure with optimal reperfusion during primary percutaneous coronary intervention followed by delayed angiography and OCT...
June 19, 2018: Archives of Cardiovascular Diseases
https://read.qxmd.com/read/29880238/antipsychotic-treatment-of-very-late-onset-schizophrenia-like-psychosis-atlas-a-randomised-controlled-double-blind-trial
#13
Robert Howard, Elizabeth Cort, Rosie Bradley, Emma Harper, Linda Kelly, Peter Bentham, Craig Ritchie, Suzanne Reeves, Waleed Fawzi, Gill Livingston, Andrew Sommerlad, Sabu Oomman, Ejaz Nazir, Ramin Nilforooshan, Robert Barber, Chris Fox, Ajay Verma Macharouthu, Pranathi Ramachandra, Vivek Pattan, John Sykes, Val Curran, Cornelius Katona, Tom Dening, Martin Knapp, Richard Gray
BACKGROUND: Very late (aged ≥60 years) onset schizophrenia-like psychosis occurs frequently but no placebo-controlled, randomised trials have assessed the efficacy and risks of antipsychotic treatment. We investigated whether low-dose amisulpride (100 mg daily) is superior to placebo in reducing psychosis symptoms over 12 weeks and whether any benefit is maintained by continuing treatment after 12 weeks. METHODS: The ATLAS double-blind controlled trial enrolled participants from 25 old age psychiatry services in the UK...
July 2018: Lancet Psychiatry
https://read.qxmd.com/read/29862630/symptom-relief-and-anejaculation-after-aquablation-or-transurethral-resection-of-the-prostate-subgroup-analysis-from-a-blinded-randomized-trial
#14
Mark Plante, Peter Gilling, Neil Barber, Mohamed Bidair, Paul Anderson, Mark Sutton, Tev Aho, Eugene Kramolowsky, Andrew Thomas, Barrett Cowan, Ronald P Kaufman, Andrew Trainer, Andrew Arther, Gopal Badlani, Mihir Desai, Leo Doumanian, Alexis E Te, Mark DeGuenther, Claus Roehrborn
OBJECTIVE: To test the hypothesis that benign prostatic hyperplasia (BPH) robotic surgery with aquablation would have a more pronounced benefit in certain patient subgroups, such as men with more challenging anatomies (e.g. large prostates, large middle lobes) and men with moderate BPH. METHODS: We conducted prespecified and post hoc exploratory subgroup analyses from a double-blind, multicentre prospective randomized controlled trial that compared transurethral resection of the prostate (TURP) using either standard electrocautery vs surgery using robotic waterjet (aquablation) to determine whether certain baseline factors predicted more marked responses after aquablation as compared with TURP...
June 4, 2018: BJU International
https://read.qxmd.com/read/29690924/the-effect-of-regularly-dosed-paracetamol-versus-no-paracetamol-on-renal-function-in-plasmodium-knowlesi-malaria-packnow-study-protocol-for-a-randomised-controlled-trial
#15
Daniel J Cooper, Katherine Plewes, Matthew J Grigg, Giri S Rajahram, Kim A Piera, Timothy William, Mark D Chatfield, Tsin Wen Yeo, Arjen M Dondorp, Nicholas M Anstey, Bridget E Barber
BACKGROUND: Plasmodium knowlesi is the most common cause of human malaria in Malaysia. Acute kidney injury (AKI) is a frequent complication. AKI of any cause can have long-term consequences, including increased risk of chronic kidney disease, adverse cardiovascular events and increased mortality. Additional management strategies are therefore needed to reduce the frequency and severity of AKI in malaria. In falciparum malaria, cell-free haemoglobin (CFHb)-mediated oxidative damage contributes to AKI...
April 24, 2018: Trials
https://read.qxmd.com/read/29519778/outcome-of-critically-ill-patients-undergoing-mandatory-insulin-therapy-compared-to-usual-care-insulin-therapy-protocol-for-a-pilot-randomized-controlled-trial
#16
Peter J Watkinson, Vicki S Barber, J Duncan Young
BACKGROUND: Observational and interventional studies in patients with both acute medical conditions and long-standing diabetes have shown that improved blood glucose control confers a survival advantage or reduces complication rates. Policies of "tight" glycaemic control were rapidly adopted by many general intensive care units (ICUs) worldwide in the mid 00's, even though the results of the studies were not generalizable to mixed medical/surgical ICUs with different intravenous feeding policies...
March 8, 2018: JMIR Research Protocols
https://read.qxmd.com/read/29360529/water-a-double-blind-randomized-controlled-trial-of-aquablation-%C3%A2-vs-transurethral-resection-of-the-prostate-in-benign-prostatic-hyperplasia
#17
Peter Gilling, Neil Barber, Mohamed Bidair, Paul Anderson, Mark Sutton, Tev Aho, Eugene Kramolowsky, Andrew Thomas, Barrett Cowan, Ronald P Kaufman, Andrew Trainer, Andrew Arther, Gopal Badlani, Mark Plante, Mihir Desai, Leo Doumanian, Alexis E Te, Mark DeGuenther, Claus Roehrborn
PURPOSE: We compared the safety and efficacy of Aquablation and transurethral prostate resection for the treatment of lower urinary tract symptoms related to benign prostatic hyperplasia. MATERIALS AND METHODS: In a double-blind, multicenter, prospective, randomized, controlled trial 181 patients with moderate to severe lower urinary tract symptoms related to benign prostatic hyperplasia underwent transurethral prostate resection or Aquablation. The primary efficacy end point was the reduction in International Prostate Symptom Score at 6 months...
May 2018: Journal of Urology
https://read.qxmd.com/read/29357947/overnight-auto-adjusting-continuous-airway-pressure-standard-care-compared-with-standard-care-alone-in-the-prevention-of-morbidity-in-sickle-cell-disease-phase-ii-poms2b-study-protocol-for-a-randomised-controlled-trial
#18
Jo Howard, April E Slee, Simon Skene, Baba Inusa, Jamie Kawadler, Michelle Downes, Johanna Gavlak, Melanie Koelbel, Hanne Stotesbury, Maria Chorozoglou, Susan Tebbs, Subarna Chakravorty, Moji Awogbade, David C Rees, Atul Gupta, Patrick B Murphy, Nicholas Hart, Sati Sahota, Carol Nwosu, Maureen Gwam, Dawn Saunders, Vivek Muthurangu, Nathaniel Barber, Emmanuel Ako, Swee Lay Thein, Melanie Marshall, Isabel C Reading, Man Ying Edith Cheng, Fenella J Kirkham, Christina Liossi
BACKGROUND: In addition to pain, sickle cell anaemia (HbSS) complications include neurocognitive difficulties in attention and processing speed associated with low daytime and night-time oxygen saturation compounded by obstructive sleep apnoea (OSA). In the general population OSA is treated with continuous positive airways pressure (CPAP). The aim of this single-blind, randomised, controlled phase II trial is to compare auto-adjusting CPAP (APAP) with standard care to standard care alone in individuals with HbSS to determine whether the intervention improves attention and processing speed, brain structure, pain and quality of life...
January 22, 2018: Trials
https://read.qxmd.com/read/29206902/managing-asbestos-containing-materials-in-the-built-environment-report-of-a-health-and-safety-executive-and-government-office-for-science-workshop
#19
Jo Bowen, Laurie Davies, Garry John Burdett, Christopher Michael Barber
The duty to manage asbestos in non-domestic premises is described in the Control of Asbestos Regulations 2012. Health and Safety Executive (HSE) policy and guidance on asbestos in the built environment in Great Britain is that asbestos-containing materials (ACMs) that are in good condition and unlikely to be disturbed can be managed in place. Where ACMs are in poor condition or likely to be disturbed they should be repaired, encapsulated or, if necessary, removed. HSE and Government Office for Science hosted a stakeholder workshop to consider evidence on the management of ACMs in public buildings...
January 1, 2017: Annals of Work Exposures and Health
https://read.qxmd.com/read/29191873/time-for-a-time-window-extension-insights-from-late-presenters-in-the-escape-trial
#20
J W Evans, B R Graham, P Pordeli, F S Al-Ajlan, R Willinsky, W J Montanera, J L Rempel, A Shuaib, P Brennan, D Williams, D Roy, A Y Poppe, T G Jovin, T Devlin, B W Baxter, T Krings, F L Silver, D F Frei, C Fanale, D Tampieri, J Teitelbaum, D Iancu, J Shankar, P A Barber, A M Demchuk, M Goyal, M D Hill, B K Menon
BACKGROUND AND PURPOSE: The safety and efficacy of endovascular therapy for large-artery stroke in the extended time window is not yet well-established. We performed a subgroup analysis on subjects enrolled within an extended time window in the Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke (ESCAPE) trial. MATERIALS AND METHODS: Fifty-nine of 315 subjects (33 in the intervention group and 26 in the control group) were randomized in the ESCAPE trial between 5...
January 2018: AJNR. American Journal of Neuroradiology
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