Ocílio Ribeiro Gonçalves, Vitor E A Ribeiro, Maria T L Galvão, Raquel Oliveira de Sousa Silva, Milene V S Sobral, Giovana S A Kojima, João L R Freitas, Victor G Soares, Benjamim B de Azevedo, Caroline Baima de Melo
Certain guidelines recommend a second-generation H1-antihistamine (AH) as first-line treatment for patients with chronic urticaria (CU). However, some patients show insufficient response to a standard dose of this therapy and might benefit from adding leukotriene receptor antagonists (LTA). Therefore, we aimed to perform a systematic review and meta-analysis comparing LTA plus antihistamines with antihistamines alone. We performed a systematic review and meta-analysis, searching PubMed, EMBASE, and Cochrane Central for randomized clinical trial (RCT) data comparing LTA plus AH treatment to AH alone in patients with CU...
April 22, 2024: International Journal of Dermatology