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JOURNAL ARTICLE
Abdelhfeez Moshrif, Rasha Abdel Noor, Hany Aly, Mohamed Mortada, Ahmed Hafez
AIM: To investigate the prevalence and features of degenerative enthesopathic changes in a large cohort of healthy individuals by musculoskeletal ultrasound (MSUS) and their relation to age and other demographic features. METHODS: In this cross-sectional study, 147 healthy subjects (1470 entheses) were examined by MSUS according to the Outcome Measures in Rheumatology guidelines: Achilles tendon, plantar fascia, patellar, and quadriceps insertions of both lower limbs...
April 2022: International Journal of Rheumatic Diseases
#82
JOURNAL ARTICLE
Gianluca Smerilli, Edoardo Cipolletta, Giulia Maria Destro Castaniti, Andrea Di Matteo, Marco Di Carlo, Erica Moscioni, Francesca Francioso, Riccardo Mashadi Mirza, Walter Grassi, Emilio Filippucci
OBJECTIVE: To explore the association of the Outcome Measures in Rheumatology ultrasound (US) entheseal abnormalities with the presence of US joint bone erosions in psoriatic arthritis (PsA). METHODS: Consecutive patients with PsA were included in this cross-sectional study. Demographic and clinical variables were collected. A bilateral US assessment was carried out at the following entheses: plantar fascia, and the quadriceps, patellar (proximal and distal), and Achilles tendons...
February 1, 2022: Journal of Rheumatology
#83
JOURNAL ARTICLE
Antonio Marchesoni, Pierluigi Macchioni, Stefania Gasparini, Carlo Perricone, Fabio Massimo Perrotta, Rosa Daniela Grembiale, Ettore Silvagni, Roberta Ramonda, Luisa Costa, Alen Zabotti, Giacomo Curradi, Giuliana Gualberti, Francesca Marando, Carlo Salvarani
In psoriatic arthritis (PsA) patients with concomitant chronic widespread pain, the differential diagnosis with fibromyalgia syndrome (FMS) can be challenging. We evaluated whether ultrasound (US) examination of entheseal sites can distinguish pain from (PsA) enthesitis versus FMS. PsA and FMS patients underwent clinical evaluation and gray-scale (GS; B-mode) and power Doppler (PD) US examination of the entheses. At least one enthesis with GS- and PD-mode changes was found in 90% and 59.3% of PsA patients ( n = 140) and 62...
December 29, 2021: Journal of Clinical Medicine
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JOURNAL ARTICLE
Atlas Mashayekhi Sardoo, Agna Neto, Rita Pinheiro Torres, Santiago Rodrigues-Manica, Lúcia Domingues, Carolina Lage Crespo, João Lagoas-Gomes, Vasco Mascarenhas, César S Mendes, Antonio Galzerano, Sérgio Fernandes de Almeida, Alexandre Sepriano, Sofia Ramiro, Alfonse T Masi, Kalyani Nair, Julia Costa, Bruno Miguel Alexandre, Tatiana Vassilevskaia, Celso Vladimiro Cunha, Daniel Sobral, Jaime Cunha Branco, Patrícia Gomes-Alves, Fernando M Pimentel-Santos
BACKGROUND: Axial Spondyloarthritis (axSpA) is a chronic, inflammatory rheumatic disease that affects the axial skeleton, causing pain, stiffness, and fatigue. Genetics and environmental factors such as microbiota and microtrauma are known causes of disease susceptibility and progression. Murine models of axSpA found a decisive role for biomechanical stress as an inducer of enthesitis and new bone formation. Here, we hypothesize that muscle properties in axSpA patients are compromised and influenced by genetic background...
October 2021: Acta Reumatológica Portuguesa
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JOURNAL ARTICLE
Yiyi Wang, Lingyan Zhang, Min Yang, Yanze Cao, Mingxin Zheng, Yuanxia Gu, Hongxiang Hu, Hui Chen, Min Zhang, Jingyi Li, Li Qiu, Wei Li
INTRODUCTION: This study aimed to develop a predictive model based on ultrasound variables which can be used to screen patients with psoriasis who are prone to progress to psoriatic arthritis (PsA) in clinical practice. METHODS: This is a cross-sectional study conducted in a single center from October 2018 to November 2020. All subjects (non-PsA group, PsA group, and control group) underwent an ultrasound examination and their ultrasound abnormalities were recorded...
February 2022: Dermatology and Therapy
#86
JOURNAL ARTICLE
Z B Song, Y Geng, X R Deng, X H Zhang, Z L Zhang
OBJECTIVE: To explore the difference in phenotype recognition of PsA patients in two clinical scenarios, physical examination with and without ultrasound assessment. METHODS: PsA patients who visited the rheumatology and clinical immunology department of Peking University First Hospital between January 2010 and October 2020, with complete data of clinical and ultrasound assessment were enrolled. The phenotypes were first identified based on physical examination only, and then combined with enthesitis and dactylitis shown on power doppler and gray-scale ultrasound...
December 18, 2021: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
#87
JOURNAL ARTICLE
J K Schreiner, D Scheicht, P Karakostas, F Recker, J Ziob, C Behning, P Preuss, P Brossart, V S Schäfer
OBJECTIVE: The purpose of this study was to determine the prevalence of joint, enthesis, bursa, and tendon ultrasound findings in large and medium joints of young, healthy individuals. METHOD: Ultrasound assessment of large and medium joints, bursae, tendons, and entheses was performed in healthy individuals below the age of 30 years. Participants also underwent bioelectrical impedance analysis and conducted supervised weight training to determine maximum strength...
December 14, 2021: Scandinavian Journal of Rheumatology
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JOURNAL ARTICLE
Sayam Dubash, Oras A Alabas, Xabier Michelena, Leticia Garcia-Montoya, Richard J Wakefield, Philip S Helliwell, Paul Emery, Dennis G McGonagle, Ai Lyn Tan, Helena Marzo-Ortega
OBJECTIVE: To characterise the impact of dactylitis in disease-modifying antirheumatic drug (DMARD)-naive early psoriatic arthritis (PsA). METHODS: Patients with early PsA meeting the classification criteria for PsA (CASPAR) were recruited. Clinical outcomes were recorded, and ultrasonography was conducted to assess grey scale (GS) and power Doppler (PD) synovitis, periarticular cortical bone erosions and enthesitis. The cohort was dichotomised by the presence or absence of dactylitis...
April 2022: Annals of the Rheumatic Diseases
#89
JOURNAL ARTICLE
Ashley Elliott, Adrian Pendleton, Gary Wright, Madeleine Rooney
OBJECTIVE: Psoriatic nail disease is more common in PsA than in isolated skin psoriasis (PsO). The nail is closely integrated to the DIP joint entheses. US data have shown that those patients with nail disease in PsO are more likely to have systemic enthesitis. We examined whether there was a relationship between nail disease, DIP enthesitis and systemic enthesitis in established PsA. METHODS: Forty-six PsA participants with nail disease underwent US scanning of the nail unit and the DIP entheses along with peripheral entheseal sites according to the Madrid sonographic enthesitis index (MASEI)...
2021: Rheumatology Advances in Practice
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JOURNAL ARTICLE
Sara Kamp Felbo, Lene Terslev, Inge Juul Sørensen, Oliver Hendricks, Dorota Kuettel, Rasmus Lederballe Pedersen, Stavros Chrysidis, Anne Duer, Claus Zachariae, Lone Skov, Mikkel Østergaard
OBJECTIVE: To investigate and compare clinical features and US signs of inflammation in joints and entheses in patients with psoriasis with and without musculoskeletal pain, and the additional value of US in classification of PsA. Furthermore, to explore the association between such findings and patient-reported outcomes (PROs) and the performance of screening-questionnaires for identifying patients with PsA. METHODS: Patients with psoriasis (n = 126) recruited from a nationwide survey were evaluated at one of four rheumatology departments...
July 6, 2022: Rheumatology
#91
JOURNAL ARTICLE
Aimie Patience, Martijn P Steultjens, Gordon J Hendry
Objectives: The objectives were to evaluate the methodological and reporting quality of ultrasound (US) studies of Achilles enthesitis in people with psoriatic arthritis (PsA), to identify the definitions and scoring systems adopted and to estimate the prevalence of ultrasound features of Achilles enthesitis in this population. Methods: A systematic literature review was conducted using the AMED, CINAHL, MEDLINE, ProQuest and Web of Science databases. Eligible studies had to measure US features of Achilles enthesitis in people with PsA...
November 2021: Rheumatology Advances in Practice
#92
JOURNAL ARTICLE
Hang Zhou, Lanyan Qiu, Pengfei Sun, Xi Liu, Xiangdong Hu, Mojun Chen, Wei Wei, Letian Chen, Shuju Song, Ting Duan, Jian Zhao
OBJECTIVE: To investigate the clinical joints manifestations under musculoskeletal ultrasound (MSUS) and hematological findings in patients with psoriatic arthritis (PsA), which may provide a basis for improving the early diagnosis of PsA. METHODS: From September 2016 to February 2021, 328 patients with psoriasis visited the dermatological and rheumatic outpatient of the Beijing Friendship Hospital were enrolled in this retrospective study. Patients were enrolled according to a paired-design method...
April 2022: Clinical Rheumatology
#93
JOURNAL ARTICLE
Zhibo Song, Xuerong Deng, Wenhui Xie, Borui Li, Zhuoli Zhang
INTRODUCTION: The clinical features of psoriatic arthritis (PsA) varied in different studies from different countries, nevertheless rarely reported from China. We aimed to show the portraits of Chinese PsA patients. METHODS: Demographics as well as clinical and laboratory data at the first visit of a PsA cohort were collected. Joints and entheses were further assessed by imaging techniques. The correlation between psoriasis severity index (PASI) and disease activity in PsA (DAPSA) was analyzed...
December 2021: Rheumatology and Therapy
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JOURNAL ARTICLE
Maria Antonietta D'Agostino, Georg Schett, Alejandra López-Rdz, Ladislav Šenolt, Katalin Fazekas, Ruben Burgos-Vargas, Jose Maldonado-Cocco, Esperanza Naredo, Philippe Carron, Anne-Marie Duggan, Punit Goyanka, Maarten Boers, Corine Gaillez
OBJECTIVES: To investigate the dynamics of response of synovitis to interleukin (IL)-17A inhibition with secukinumab in patients with active psoriatic arthritis (PsA) using Power Doppler ultrasound. METHODS: The randomised, placebo-controlled, Phase III ULTIMATE study enrolled PsA patients with active ultrasound synovitis, and clinical synovitis and enthesitis having an inadequate response to conventional disease-modifying anti-rheumatic drugs (DMARDs) and naïve to biologic DMARDs...
September 16, 2021: Rheumatology
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JOURNAL ARTICLE
Plamen Todorov Todorov, Lili Mekenjan, Rodina Nestorova, Anastas Batalov
AIM: To describe the sonoanatomy of the long posterior sacroiliac ligament (LPSL) in healthy volunteers and to assess by ultrasound the LPSL in patients with noninflammatory sacroiliac joint pain (SIP). MATERIAL AND METHODS: We assessed 64 LPSLs of 32 healthy controls and 40 LPSLs of 40 patients with unilateral noninflammatory SIP and a positive Fortin finger test. LPSLs in both groups were assessed for the presence of alterations in their structure, continuity and echogenicity and their thickness was measured in three predefined points...
September 11, 2021: Medical Ultrasonography
#96
JOURNAL ARTICLE
Daniela Fodor, Sebastián C Rodriguez-Garcia, Vito Cantisani, Hilde B Hammer, Wolfgang Hartung, Andrea Klauser, Carlo Martinoli, Lene Terslev, Fernando Alfageme, David Bong, Angel Bueno, Paz Collado, Maria Antonietta D'Agostino, Javier de la Fuente, Gabriella Iohom, Jens Kessler, Manuela Lenghel, Clara Malattia, Peter Mandl, Dolores Mendoza-Cembranos, Mihaela Micu, Ingrid Möller, Aurelie Najm, Levent Özçakar, Riccardo Picasso, Athena Plagou, Xavier Sala-Blanch, Luca Maria Sconfienza, Oana Serban, Paolo Simoni, Iwona Sudoł-Szopińska, Christian Tesch, Plamen Todorov, Jacqueline Uson, Violeta Vlad, Federico Zaottini, Diana Bilous, Roxana Gutiu, Michael Pelea, Anamaria Marian, Esperanza Naredo
The first part of the guidelines and recommendations for musculoskeletal ultrasound, produced under the auspices of the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB), provides information about the use of musculoskeletal ultrasound for assessing extraarticular structures (muscles, tendons, entheses, ligaments, bones, bursae, fasciae, nerves, skin, subcutaneous tissues, and nails) and their pathologies. Clinical applications, practical points, limitations, and artifacts are described and discussed for every structure...
February 2022: Ultraschall in der Medizin
#97
REVIEW
Gianluca Smerilli, Andrea Di Matteo, Edoardo Cipolletta, Walter Grassi, Emilio Filippucci
PURPOSE OF REVIEW: To provide an overview of the ultrasound (US) studies focusing on enthesitis in psoriatic arthritis (PsA). RECENT FINDINGS: Last-generation US equipment has demonstrated the ability to detect subtle morphostructural and vascular abnormalities at entheseal level. US is able to identify pathologic changes in both "classical" (i.e., the site of attachment of tendons, ligaments, and joint capsules into the bone) and "functional" entheses (i.e., anatomical regions where tendons or ligaments wrap around bony pulleys)...
August 24, 2021: Current Rheumatology Reports
#98
JOURNAL ARTICLE
Juan Molina Collada, Lucía Mayordomo
BACKGROUND AND OBJECTIVE: Ultrasound has been included in the training of residents in rheumatology in recent years, as a result of its increased use in daily clinical practice. Our objective is to evaluate the perceived quality of ultrasound training of residents in rheumatology services in Spain. MATERIAL AND METHODS: Online survey aimed at rheumatologists who began their training in rheumatology between 2009 and 2019. RESULTS: One hundred thirty-nine rheumatologists participated in the survey, of which 97...
August 6, 2021: Reumatología clinica
#99
JOURNAL ARTICLE
Tsai-Hung Yen, Chih-Wei Tseng, Hsin-Hua Chen, Yi-Da Wu, Chung-Yang Yen, Chien-Shan Chiu, Chao-Kuei Juan, Kuo-Lung Lai
OBJECTIVES: The evolution of psoriasis (PsO) to psoriatic arthritis (PsA) has been proposed recently. There are three phases that occur in sequence prior to classifiable PsA: PsO patients, PsO patients with a positive imaging, and PsO patients with arthralgia not explained by other diagnosis. The purpose of this study was to compare the differences among preclinical phases using ultrasound and clinical assessment. METHODS: Patients with psoriasis were recruited...
August 5, 2021: Clinical and Experimental Rheumatology
#100
JOURNAL ARTICLE
Nelgin Gerenli, Betül Sözeri
BACKGROUND: Enthesitis is an extra-intestinal manifestation of inflammatory bowel disease (IBD) which often remains underdiagnosed in children. We aimed to evaluate the frequency of enthesitis in pediatric IBD patients using physical examination and ultrasound (US) assessment as the reference standard. METHODS: 31 children, 7 -18 years of age, diagnosed with IBD were recruited for a cross-sectional study. All subjects completed a study questionnaire and underwent both physical and US examination for the presence of the enthesitis...
2021: Turkish Journal of Pediatrics
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