Angela Santoro, Antonio Travaglino, Michele Valente, Damiano Arciuolo, Giulia Scaglione, Nicoletta D'Alessandris, Stefania Sfregola, Francesca Addante, Caterina Fulgione, Antonio Raffone, Angelo Minucci, Frediano Inzani, Gian Franco Zannoni
Pilomatrix-like high-grade endometrioid carcinoma (PiMHEC) has recently been described as an aggressive variant of endometrial carcinoma. Herein, we described a case of ovarian PiMHEC, comparing it to endometrial PiMHEC and assessing previously published cases of putative ovarian PiMHEC. A 65-year-old woman underwent hysterectomy for an ovarian tumor characterized by solid nests of basaloid cells with prominent ghost cell keratinization. Immunohistochemistry showed nuclear β-catenin and CDX2 expression and loss of estrogen and progesterone receptors and PAX8...
December 13, 2022: Diagnostics