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Subarachnoid bleed

Nazife Dinc, Sae-Yeon Won, Johanna Quick-Weller, Joachim Berkefeld, Volker Seifert, Gerhard Marquardt
Subarachnoid hemorrhage as bleeding pattern occurs rarely in ruptured arteriovenous malformations (AVM). The aim of the present study is to evaluate different bleeding patterns in hemorrhages due to an AVM and their impact on outcome in terms of risk and treatment stratification. We evaluated 158 patients with ruptured AVMs who were admitted to our neurosurgical department from 2002 to 2017. We compared different bleeding patterns, such as intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), or both (ICH + SAH) and evaluated predictive variables for outcome in the last follow-up...
March 5, 2019: Neurosurgical Review
Motohisa Koga, Takachika Aoki, Tetsuya Negoto, Takehiro Makizono, Keisuke Sugi, Kana Fujimori, Sosho Kajiwara, Satoru Komaki, Munetake Yoshitomi, Yasuo Sugita, Motohiro Morioka
BACKGROUND: Several possible mechanisms exist for the spread of a primary tumor to the leptomeninges in leptomeningeal carcinomatosis. This report describes a case caused by direct bleeding in the subarachnoid space from a neoplastic cerebral aneurysm rupture. CASE DESCRIPTION: A 48-year-old Japanese woman, who was diagnosed with breast carcinoma (pT3 pN2 M0) at the age of 45 years and underwent mastectomy and chemotherapy, was admitted in a coma following a sudden-onset severe headache...
February 26, 2019: World Neurosurgery
Morgan J Bressington, Gulam Zilani, Dmitri Shastin, Chirag Patel
Spinal arachnoid cysts (SAC) are rare in isolation and the exact aetiology is still debated. Primary (congenital) cysts are caused by structural abnormalities in the arachnoid layer and largely affect the thoracic region. Secondary cysts are induced by a multitude of factors, infection, trauma or iatrogenic response, and can affect any level of the spinal cord. While subarachnoid haemorrhage (SAH) is a relatively common condition with significant repercussions, it is extremely uncommonly associated with SAC...
February 27, 2019: BMJ Case Reports
Hideki Kanamaru, Hidenori Suzuki
Aneurysmal subarachnoid hemorrhage remains serious hemorrhagic stroke with high morbidities and mortalities. Aneurysm rupture causes arterial bleeding-induced mechanical brain tissue injuries and elevated intracranial pressure, followed by global cerebral ischemia. Post-subarachnoid hemorrhage ischemia, tissue injuries as well as extravasated blood components and the breakdown products activate microglia, astrocytes and Toll-like receptor 4, and disrupt blood-brain barrier associated with the induction of many inflammatory and other cascades...
July 2019: Neural Regeneration Research
Pietro Panni, Elisa Colombo, Carmine Antonio Donofrio, Lina Raffaella Barzaghi, Luigi Albano, Claudio Righi, Francesco Scomazzoni, Franco Simionato, Pietro Mortini, Andrea Falini, Nicoletta Anzalone
BACKGROUND: Volumetric assessment of aneurysmal bleeding has been evaluated in few studies and emerged as a promising outcome predictor. There is a lack of studies evaluating its impact in the poor-grade population. METHODS: Retrospective review of 63 consecutive poor-grade aneurysmal subarachnoid hemorrhage (aSAH) patients, defined as grade IV and V according to the World Federation of Neurological Surgeons (WFNS) classifications. Global intracranial bleeding volume was calculated with its subarachnoid, intracerebral (ICH), and intraventricular (IVH) portions by means of analytical software...
February 21, 2019: Acta Neurochirurgica
Sung-Min Cho, Nader Moazami, Stuart Katz, Randall Starling, Jennifer A Frontera
BACKGROUND: Little data exists regarding reversal and resumption of antithrombotics following left ventricular assist device (LVAD)-associated intracranial hemorrhage (ICH). METHODS: Prospectively collected data of LVAD patients with ICH was reviewed. Coagulopathy reversal agents, antithrombotic regimens and thrombotic (venous thromboembolism, ischemic stroke, myocardial infarction) and hemorrhagic (recurrent ICH, gastrointestinal bleed, anemia requiring transfusion) complications were recorded...
February 11, 2019: Annals of Thoracic Surgery
Lucrecia Bandeo, Astrid Rausch, Miguel Saucedo, Anibal Chertcoff, Luciana Leon Cejas, Claudia Uribe Roca, Sol Pacha, Manuel Fernandez Pardal, Ricardo Reisin, Pablo Bonardo
The TNF-α antagonists are the drugs used for the treatment of ulcerative colitis (UC). Nontraumatic convexity subarachnoid hemorrhage is an infrequent nonaneurysmal subtype of subarachnoid bleeding caused mainly by reversible cerebral vasoconstriction syndrome (RCVS), cerebral amyloid angiopathy, and posterior reversible encephalopathy syndrome (PRES). We present a 26-year-old female patient with a diagnosis of UC taking Adalimumab. She received her last doses the same day she was admitted to our hospital for an acute severe UC exacerbation...
November 2018: Journal of Vascular and Interventional Neurology
Andreas Nørgaard Glud, Steen Jakobsen, Anne M Landau, Aage Kristian Olsen Alstrup, Jens Christian Hedemann Sørensen
BACKGROUND: Intrathecal (IT) delivery is useful in both basic research and clinical treatments. Here we aim to test a new minimally invasive distribution route to the subarachnoid space (SAS) and the flow of IT administrations. We placed a radioligand into SAS during positron emission tomography (PET) scanning as a proof of concept. NEW METHOD: We injected a 11 C-labeled PET-tracer using a surgically placed catheter in the cisterna magna of anesthetized female pigs...
February 7, 2019: Journal of Neuroscience Methods
Kevin Akeret, Menno Germans, Wenhua Sun, Zsolt Kulcsar, Luca Regli
BACKGROUND: and Importance: Cerebral arteriovenous malformations (CAVM) are characterized by altered hemodynamics and associated with angioanatomical changes, such as aneuryms. We encountered a patient with a CAVM-associated dissection of the medial trunk of the posterior inferior cerebellar artery (PICA) instead of an aneurysm. CLINICAL PRESENTATION: We report the case of a 56-year old male patient with spontaneous subarachnoid hemorrhage within the cisterna magna and fourth ventricle...
February 2, 2019: World Neurosurgery
Tomaz Velnar, Tilen Zele, Roman Bosnjak
The number of invasive procedures in medicine is increasing, as is the employment of new technological achievements. In the era of information-communication technology, one such achievement is also the telemedicine network. In Slovenia, it is known as the Telekap (TeleStroke) network, which was primarily designed for fast and efficient management of stroke patients. In the neurosurgical community, the system is frequently used also for conveying vital information regarding subarachnoid haemorrhage and trauma...
January 18, 2019: World Journal of Methodology
Faris Haddadin, Alba Munoz Estrella, Eyal Herzog
Hypertensive crisis is a serious medical condition defined as severely elevated blood pressure; typically the systolic blood pressure is above 180 mmHg, and/or the diastolic blood pressure is above 120 mmHg. Hypertensive crises are divided into two categories: hypertensive urgency and hypertensive emergency. Hypertensive urgency is asymptomatic while hypertensive emergency presents with end-organ damage requiring more aggressive blood-pressure lowering. The common presentations for neurological end-organ dysfunction in conjunction with hypertensive emergency include ischemic strokes, intracranial hemorrhage, subarachnoid hemorrhage, head trauma, and hypertensive encephalopathy...
January 2019: Journal of Cardiology Cases
Marvin Darkwah Oppong, Kathrin Buffen, Daniela Pierscianek, Annika Herten, Yahya Ahmadipour, Philipp Dammann, Laurèl Rauschenbach, Michael Forsting, Ulrich Sure, Ramazan Jabbarli
OBJECTIVEClinical data on secondary hemorrhagic complications (SHCs) in patients with aneurysmal subarachnoid hemorrhage (SAH) are sparse and mostly limited to ventriculostomy-associated SHCs. This study aimed to elucidate the incidence, risk factors, and impact on outcome of SHCs in a large cohort of SAH patients.METHODSAll consecutive patients with ruptured aneurysms treated between January 2003 and June 2016 were eligible for this study. Patients' charts were reviewed for clinical data, and imaging studies were reviewed for radiographic data...
January 25, 2019: Journal of Neurosurgery
Nuno Ferreira Monteiro, Patrícia Cipriano, Elga Freire
INTRODUCTION: Acute neurological illness often results in severe disability. Five-year life expectancy is around 40%; half the survivors become completely dependent on outside help. OBJECTIVE: Evaluate the symptoms of patients admitted to a Hospital ward with a diagnosis of stroke, subarachnoid hemorrhage or subdural hematoma, and analyze the role of an In-Hospital Palliative Care Support Team. MATERIAL AND METHODS: Retrospective, observational study with a sample consisting of all patients admitted with acute neurological illness and with a guidance request made to the In-Hospital Palliative Care Support Team of a tertiary Hospital, over 5 years (2012-2016)...
September 2018: Revista da Associação Médica Brasileira
Jianfeng Zheng, Rui Xu, Zongduo Guo, Xiaochuan Sun
OBJECTIVE: The risk of hemorrhagic events in small ruptured aneurysms remains unclear. Due to less arterial wall, small ruptured aneurysms may be correlated with massive bleeding and rebleeding. Therefore, it may contribute to treatment to evaluate the amount of bleeding and the risk of rebleeding in small ruptured aneurysms. METHODS: A retrospective cohort study of all consecutive patients with intracranial aneurysms admitted to our hospital from February 2013 to December 2017 was carried out...
January 13, 2019: Neurological Research
M Hollingworth, A A B Jamjoom, D Bulters, H C Patel
BACKGROUND: Delayed cerebral ischemia (DCI) is an independent predictor of an unfavorable outcome after aneurysmal subarachnoid hemorrhage (aSAH). Many centers, but not all, use transcranial Doppler (TCD) to screen for vasospasm to help predict DCI. We used the United Kingdom and Ireland Subarachnoid Haemorrhage (UKISAH) Registry to see if outcomes were better in centers that used TCD to identify vasospasm compared to those that did not. METHODS: TCD screening practices were ascertained by national survey in 13 participating centers of the UKISAH...
January 12, 2019: Acta Neurochirurgica
Katherine Z Isoardi, Sarah F Ayles, Keith Harris, Clare J Finch, Colin B Page
OBJECTIVE: There is little recent published data characterising methamphetamine intoxication. The present study aims to describe the clinical effects, management, complications and disposition of patients with methamphetamine exposure. METHODS: This is a retrospective review of patients presenting with methamphetamine intoxication to an ED in 2016. All presentations were extracted from a relational database and each medical record reviewed. Demographics, clinical features, complications and disposition were extracted...
December 28, 2018: Emergency Medicine Australasia: EMA
Rahul Raj, Riitta Rautio, Johanna Pekkola, Melissa Rahi, Mikko Sillanpää, Jussi Numminen
BACKGROUND: The Woven EndoBridge (WEB) device is a new treatment modality developed for broad-necked unruptured intracranial aneurysms (IA) but shows potential for the treatment of ruptured IAs as well. Our aim was to describe 6-month aneurysm obliteration rates, clinical outcomes and procedure related complications after WEB treatment for ruptured IAs from two academic centers. METHODS: We conducted a retrospective observational study, including all consecutive patients treated with the WEB device (WEB Single Layer [SL] and Single-Layer Sphere [SLS]) for a ruptured IA causing acute subarachnoid hemorrhage (SAH) between 2014 (start of use) and 2017...
December 18, 2018: World Neurosurgery
Jun Yup Kim, Kyusik Kang, Jihoon Kang, Jaseong Koo, Dae-Hyun Kim, Beom Joon Kim, Wook-Joo Kim, Eung-Gyu Kim, Jae Guk Kim, Jeong-Min Kim, Joon-Tae Kim, Chulho Kim, Hyun-Wook Nah, Kwang-Yeol Park, Moo-Seok Park, Jong-Moo Park, Jong-Ho Park, Tai Hwan Park, Hong-Kyun Park, Woo-Keun Seo, Jung Hwa Seo, Tae-Jin Song, Seong Hwan Ahn, Mi-Sun Oh, Hyung Geun Oh, Sungwook Yu, Keon-Joo Lee, Kyung Bok Lee, Kijeong Lee, Sang-Hwa Lee, Soo Joo Lee, Min Uk Jang, Jong-Won Chung, Yong-Jin Cho, Kang-Ho Choi, Jay Chol Choi, Keun-Sik Hong, Yang-Ha Hwang, Seong-Eun Kim, Ji Sung Lee, Jimi Choi, Min Sun Kim, Ye Jin Kim, Jinmi Seok, Sujung Jang, Seokwan Han, Hee Won Han, Jin Hyuk Hong, Hyori Yun, Juneyoung Lee, Hee-Joon Bae
Despite the great socioeconomic burden of stroke, there have been few reports of stroke statistics in Korea. In this scenario, the Epidemiologic Research Council of the Korean Stroke Society launched the "Stroke Statistics in Korea" project, aimed at writing a contemporary, comprehensive, and representative report on stroke epidemiology in Korea. This report contains general statistics of stroke, prevalence of behavioral and vascular risk factors, stroke characteristics, pre-hospital system of care, hospital management, quality of stroke care, and outcomes...
December 18, 2018: Journal of Stroke
Marvin Darkwah Oppong, Oliver Gembruch, Daniela Pierscianek, Martin Köhrmann, Christoph Kleinschnitz, Cornelius Deuschl, Christoph Mönninghoff, Klaus Kaier, Michael Forsting, Ulrich Sure, Ramazan Jabbarli
BACKGROUND: Delayed cerebral ischemia (DCI) has a strong impact on outcome of patients with aneurysmal subarachnoid hemorrhage (SAH). Positive effect of antiplatelet therapy on DCI rates has been supposed upon smaller SAH series. OBJECTIVE: To analyze the benefit/risk profile of antiplatelet use in SAH patients. METHODS: This retrospective case-control study was based on institutional observational cohort with 994 SAH patients treated between January 2003 and June 2016...
December 13, 2018: Neurosurgery
Tobechi Mbadugha, Toshihiro Ogiwara, Alhusain Nagm, Takatoshi Hasegawa, Keisuke Kamiya, Samuel Ohaegbulam, Kazuhiro Hongo
Superficial siderosis (SS) associated with craniopharyngioma is an extremely rare occurrence. To our knowledge, only three cases have been reported in literature. Two of the cases occurred following resection of the tumor. Similar to the present case, one of the cases was discovered prior to surgical intervention, 'pure tumor-related' SS. The clinical presentation, diagnosis, management and outcome are discussed in this article. A 50-year-old man presented with an 11-month history of left-sided tinnitus, hearing impairment and a 2-month history of visual disturbance...
December 6, 2018: World Neurosurgery
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