A E Naas, L M Solden, A D Norbeck, H Brewer, L H Hagen, I M Heggenes, A C McHardy, R I Mackie, L Paša-Tolić, M Ø Arntzen, V G H Eijsink, N M Koropatkin, M Hess, K C Wrighton, P B Pope
BACKGROUND: In nature, obligate herbivorous ruminants have a close symbiotic relationship with their gastrointestinal microbiome, which proficiently deconstructs plant biomass. Despite decades of research, lignocellulose degradation in the rumen has thus far been attributed to a limited number of culturable microorganisms. Here, we combine meta-omics and enzymology to identify and describe a novel Bacteroidetes family ("Candidatus MH11") composed entirely of uncultivated strains that are predominant in ruminants and only distantly related to previously characterized taxa...
March 1, 2018: Microbiome